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Volumn 7, Issue 5, 2016, Pages 702-722

Function and evolution of the long noncoding RNA circuitry orchestrating X-chromosome inactivation in mammals

Author keywords

[No Author keywords available]

Indexed keywords

LONG UNTRANSLATED RNA;

EID: 84985972745     PISSN: 17577004     EISSN: 17577012     Source Type: Journal    
DOI: 10.1002/wrna.1359     Document Type: Article
Times cited : (41)

References (139)
  • 1
    • 84879249750 scopus 로고    scopus 로고
    • Different flavors of X-chromosome inactivation in mammals
    • Dupont C, Gribnau J. Different flavors of X-chromosome inactivation in mammals. Curr Opin Cell Biol 2013, 25:314–321.
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 314-321
    • Dupont, C.1    Gribnau, J.2
  • 2
    • 0025961771 scopus 로고
    • A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
    • Brown CJ, Ballabio A, Rupert JL, Lafreniere RG, Grompe M, Tonlorenzi R, Willard HF. A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 1991, 349:38–44.
    • (1991) Nature , vol.349 , pp. 38-44
    • Brown, C.J.1    Ballabio, A.2    Rupert, J.L.3    Lafreniere, R.G.4    Grompe, M.5    Tonlorenzi, R.6    Willard, H.F.7
  • 5
    • 0026489906 scopus 로고
    • The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus
    • Brockdorff N, Ashworth A, Kay GF, McCabe VM, Norris DP, Cooper PJ, Swift S, Rastan S. The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 1992, 71:515–526.
    • (1992) Cell , vol.71 , pp. 515-526
    • Brockdorff, N.1    Ashworth, A.2    Kay, G.F.3    McCabe, V.M.4    Norris, D.P.5    Cooper, P.J.6    Swift, S.7    Rastan, S.8
  • 6
    • 0026456701 scopus 로고
    • The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
    • Brown CJ, Hendrich BD, Rupert JL, Lafrenière RG, Xing Y, Lawrence RG, Willard HF. The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell 1992, 71:527–542.
    • (1992) Cell , vol.71 , pp. 527-542
    • Brown, C.J.1    Hendrich, B.D.2    Rupert, J.L.3    Lafrenière, R.G.4    Xing, Y.5    Lawrence, R.G.6    Willard, H.F.7
  • 7
    • 0030034051 scopus 로고    scopus 로고
    • XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure
    • Clemson CM, Mc Neil JA, Willard HF, Lawrence JB. XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J Cell Biol 1996, 132:259–275.
    • (1996) J Cell Biol , vol.132 , pp. 259-275
    • Clemson, C.M.1    Mc Neil, J.A.2    Willard, H.F.3    Lawrence, J.B.4
  • 9
    • 0027207244 scopus 로고
    • Evolutionary conservation of possible functional domains of the human and murine XIST genes
    • Hendrich BD, Brown CJ, Willard HF. Evolutionary conservation of possible functional domains of the human and murine XIST genes. Hum Mol Genet 1993, 2:663–672.
    • (1993) Hum Mol Genet , vol.2 , pp. 663-672
    • Hendrich, B.D.1    Brown, C.J.2    Willard, H.F.3
  • 11
    • 33745125901 scopus 로고    scopus 로고
    • The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene
    • Duret L, Chureau C, Samain S, Weissenbach J, Avner P. The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene. Science 2006, 312:1653–1655.
    • (2006) Science , vol.312 , pp. 1653-1655
    • Duret, L.1    Chureau, C.2    Samain, S.3    Weissenbach, J.4    Avner, P.5
  • 12
    • 80052413006 scopus 로고    scopus 로고
    • Chromatin structure and nuclear organization dynamics during X-chromosome inactivation
    • Nora E, Heard E. Chromatin structure and nuclear organization dynamics during X-chromosome inactivation. Cold Spring Harb Symp Quant Biol 2010, 75:333–344.
    • (2010) Cold Spring Harb Symp Quant Biol , vol.75 , pp. 333-344
    • Nora, E.1    Heard, E.2
  • 13
    • 0027450207 scopus 로고
    • Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation
    • Kay GF, Penny GD, Patel D, Ashworth A, Brockdorff N, Rastan S. Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell 1993, 72:171–182.
    • (1993) Cell , vol.72 , pp. 171-182
    • Kay, G.F.1    Penny, G.D.2    Patel, D.3    Ashworth, A.4    Brockdorff, N.5    Rastan, S.6
  • 14
    • 85052429967 scopus 로고    scopus 로고
    • Combined immunofluorescence, RNA fluorescent in situ hybridization, and DNA fluorescent in situ hybridization to study chromatin changes, transcriptional activity, nuclear organization, and X-chromosome inactivation
    • Chaumeil J, Augui S, Chow JC, Heard E. Combined immunofluorescence, RNA fluorescent in situ hybridization, and DNA fluorescent in situ hybridization to study chromatin changes, transcriptional activity, nuclear organization, and X-chromosome inactivation. Methods Mol Biol 2008, 463:297–308.
    • (2008) Methods Mol Biol , vol.463 , pp. 297-308
    • Chaumeil, J.1    Augui, S.2    Chow, J.C.3    Heard, E.4
  • 15
    • 0031044166 scopus 로고    scopus 로고
    • Xist-deficient mice are defective in dosage compensation but not spermatogenesis
    • Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R. Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev 1997, 11:156–166.
    • (1997) Genes Dev , vol.11 , pp. 156-166
    • Marahrens, Y.1    Panning, B.2    Dausman, J.3    Strauss, W.4    Jaenisch, R.5
  • 17
    • 0033637110 scopus 로고    scopus 로고
    • A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation
    • Wutz A, Jaenisch R. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol Cell 2000, 5:695–705.
    • (2000) Mol Cell , vol.5 , pp. 695-705
    • Wutz, A.1    Jaenisch, R.2
  • 19
    • 0030581152 scopus 로고    scopus 로고
    • A 450 kb transgene displays properties of the mammalian X-inactivation center
    • Lee JT, Strauss WM, Dausman JA, Jaenisch R. A 450 kb transgene displays properties of the mammalian X-inactivation center. Cell 1996, 86:83–94.
    • (1996) Cell , vol.86 , pp. 83-94
    • Lee, J.T.1    Strauss, W.M.2    Dausman, J.A.3    Jaenisch, R.4
  • 20
    • 0032958104 scopus 로고    scopus 로고
    • Xist yeast artificial chromosome transgenes function as X-inactivation centers only in multicopy arrays and not as single copies
    • Heard E, Mongelard F, Arnaud D, Avner P. Xist yeast artificial chromosome transgenes function as X-inactivation centers only in multicopy arrays and not as single copies. Mol Cell Biol 1999, 19:3156–3166.
    • (1999) Mol Cell Biol , vol.19 , pp. 3156-3166
    • Heard, E.1    Mongelard, F.2    Arnaud, D.3    Avner, P.4
  • 21
    • 0037173064 scopus 로고    scopus 로고
    • An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells
    • Hall LL, Byron M, Sakai K, Carrel L, Willard HF, Lawrence JB. An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells. Proc Natl Acad Sci U S A 2002, 99:8677–8682.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8677-8682
    • Hall, L.L.1    Byron, M.2    Sakai, K.3    Carrel, L.4    Willard, H.F.5    Lawrence, J.B.6
  • 22
    • 0033536067 scopus 로고    scopus 로고
    • Human XIST yeast artificial chromosome transgenes show partial X inactivation center function in mouse embryonic stem cells
    • Heard E, Mongelard F, Arnaud D, Chureau C, Vourc'h C, Avner P. Human XIST yeast artificial chromosome transgenes show partial X inactivation center function in mouse embryonic stem cells. Proc Natl Acad Sci U S A 1999, 96:6841–6846.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6841-6846
    • Heard, E.1    Mongelard, F.2    Arnaud, D.3    Chureau, C.4    Vourc'h, C.5    Avner, P.6
  • 24
    • 0036479009 scopus 로고    scopus 로고
    • Chromosomal silencing and localization are mediated by different domains of Xist RNA
    • Wutz A, Rasmussen TP, Jaenisch R. Chromosomal silencing and localization are mediated by different domains of Xist RNA. Nat Genet 2002, 30:167–174.
    • (2002) Nat Genet , vol.30 , pp. 167-174
    • Wutz, A.1    Rasmussen, T.P.2    Jaenisch, R.3
  • 25
    • 78650675579 scopus 로고    scopus 로고
    • Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome
    • Sarma K, Levasseur P, Aristarkhov A, Lee JT. Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome. Proc Natl Acad Sci U S A 2010, 107:22196–22201.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 22196-22201
    • Sarma, K.1    Levasseur, P.2    Aristarkhov, A.3    Lee, J.T.4
  • 27
    • 79959948197 scopus 로고    scopus 로고
    • YY1 tethers Xist RNA to the inactive X nucleation center
    • Jeon Y, Lee JT. YY1 tethers Xist RNA to the inactive X nucleation center. Cell 2011, 146:119–133.
    • (2011) Cell , vol.146 , pp. 119-133
    • Jeon, Y.1    Lee, J.T.2
  • 30
    • 84937960975 scopus 로고    scopus 로고
    • A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation
    • aab2276, (Epub ahead of Print; June 18, 2015).
    • Minajigi A, Froberg JE, Wei C, Sunwoo H, Kesner B, Colognori D, Lessing D, Payer B, Boukhali M, Haas W, et al. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation. Science 2015, 349. pii: aab2276. doi: 10.1126/science.aab2276. (Epub ahead of Print; June 18, 2015).
    • (2015) Science , vol.349
    • Minajigi, A.1    Froberg, J.E.2    Wei, C.3    Sunwoo, H.4    Kesner, B.5    Colognori, D.6    Lessing, D.7    Payer, B.8    Boukhali, M.9    Haas, W.10
  • 32
    • 84940758356 scopus 로고    scopus 로고
    • Xist Exon 7 contributes to the stable localization of Xist RNA on the inactive X-chromosome
    • Yamada N, Hasegawa Y, Yue M, Hamada T, Nakagawa S, Ogawa Y. Xist Exon 7 contributes to the stable localization of Xist RNA on the inactive X-chromosome. PLoS Genet 2015, 11:e1005430.
    • (2015) PLoS Genet , vol.11
    • Yamada, N.1    Hasegawa, Y.2    Yue, M.3    Hamada, T.4    Nakagawa, S.5    Ogawa, Y.6
  • 33
    • 12544256562 scopus 로고    scopus 로고
    • A stable proteinaceous structure in the territory of inactive X chromosomes
    • Fackelmayer FO. A stable proteinaceous structure in the territory of inactive X chromosomes. J Biol Chem 2005, 280:1720–1723.
    • (2005) J Biol Chem , vol.280 , pp. 1720-1723
    • Fackelmayer, F.O.1
  • 34
    • 77956607961 scopus 로고    scopus 로고
    • The matrix protein hnRNP U is required for chromosomal localization of Xist RNA
    • Hasegawa Y, Brockdorff N, Kawano S, Tsutui K, Tsutui K, Nakagawa S. The matrix protein hnRNP U is required for chromosomal localization of Xist RNA. Dev Cell 2010, 19:469–476.
    • (2010) Dev Cell , vol.19 , pp. 469-476
    • Hasegawa, Y.1    Brockdorff, N.2    Kawano, S.3    Tsutui, K.4    Tsutui, K.5    Nakagawa, S.6
  • 35
    • 77950354829 scopus 로고    scopus 로고
    • The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation
    • Pullirsch D, Hartel R, Kishimoto H, Leeb M, Steiner G, Wutz A. The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation. Development 2010, 137:935–943.
    • (2010) Development , vol.137 , pp. 935-943
    • Pullirsch, D.1    Hartel, R.2    Kishimoto, H.3    Leeb, M.4    Steiner, G.5    Wutz, A.6
  • 36
    • 84900824181 scopus 로고    scopus 로고
    • Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci
    • Smeets D, Markaki Y, Schmid VJ, Kraus F, Tattermusch A, Cerase A, Sterr M, Fiedler S, Demmerle J, Popken J, et al. Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci. Epigenetics Chromatin 2014, 7:8.
    • (2014) Epigenetics Chromatin , vol.7 , pp. 8
    • Smeets, D.1    Markaki, Y.2    Schmid, V.J.3    Kraus, F.4    Tattermusch, A.5    Cerase, A.6    Sterr, M.7    Fiedler, S.8    Demmerle, J.9    Popken, J.10
  • 37
    • 0020987354 scopus 로고
    • Mammalian X-chromosome inactivation
    • Gartler SM, Riggs AD. Mammalian X-chromosome inactivation. Annu Rev Genet 1983, 17:155–190.
    • (1983) Annu Rev Genet , vol.17 , pp. 155-190
    • Gartler, S.M.1    Riggs, A.D.2
  • 38
    • 0030895047 scopus 로고    scopus 로고
    • Long-range cis effects of ectopic X-inactivation centres on a mouse autosome
    • Lee JT, Jaenisch R. Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nature 1997, 386:275–278.
    • (1997) Nature , vol.386 , pp. 275-278
    • Lee, J.T.1    Jaenisch, R.2
  • 39
    • 0016299216 scopus 로고
    • Position effect variegation in the mouse
    • Cattanach BM. Position effect variegation in the mouse. Genet Res 1974, 23:291–306.
    • (1974) Genet Res , vol.23 , pp. 291-306
    • Cattanach, B.M.1
  • 41
    • 0031820331 scopus 로고    scopus 로고
    • X-chromosome inactivation: a repeat hypothesis
    • Lyon MF. X-chromosome inactivation: a repeat hypothesis. Cytogenet Cell Genet 1998, 80:133–137.
    • (1998) Cytogenet Cell Genet , vol.80 , pp. 133-137
    • Lyon, M.F.1
  • 42
    • 33746076412 scopus 로고    scopus 로고
    • A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced
    • Chaumeil J, Le Baccon P, Wutz A, Heard E. A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev 2006, 20:2223–2237.
    • (2006) Genes Dev , vol.20 , pp. 2223-2237
    • Chaumeil, J.1    Le Baccon, P.2    Wutz, A.3    Heard, E.4
  • 43
    • 33646743365 scopus 로고    scopus 로고
    • The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences
    • Clemson CM, Hall LL, Byron M, McNeil J, Lawrence JB. The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences. Proc Natl Acad Sci U S A 2006, 103:7688–7693.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7688-7693
    • Clemson, C.M.1    Hall, L.L.2    Byron, M.3    McNeil, J.4    Lawrence, J.B.5
  • 44
    • 84894101635 scopus 로고    scopus 로고
    • DNA methylation profiling in X; autosome translocations supports a role for L1 repeats in the spread of X chromosome inactivation
    • Bala Tannan N, Brahmachary M, Garg P, Borel C, Alnefaie R, Watson CT, Thomas NS, Sharp AJ. DNA methylation profiling in X; autosome translocations supports a role for L1 repeats in the spread of X chromosome inactivation. Hum Mol Genet 2014, 23:1224–1236.
    • (2014) Hum Mol Genet , vol.23 , pp. 1224-1236
    • Bala Tannan, N.1    Brahmachary, M.2    Garg, P.3    Borel, C.4    Alnefaie, R.5    Watson, C.T.6    Thomas, N.S.7    Sharp, A.J.8
  • 52
    • 80054719512 scopus 로고    scopus 로고
    • The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization
    • Duszczyk MM, Wutz A, Rybin V, Sattler M. The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization. RNA 2011, 17:1973–1982.
    • (2011) RNA , vol.17 , pp. 1973-1982
    • Duszczyk, M.M.1    Wutz, A.2    Rybin, V.3    Sattler, M.4
  • 54
    • 55349109963 scopus 로고    scopus 로고
    • Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
    • Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science 2008, 322:750–756.
    • (2008) Science , vol.322 , pp. 750-756
    • Zhao, J.1    Sun, B.K.2    Erwin, J.A.3    Song, J.J.4    Lee, J.T.5
  • 57
    • 0035861875 scopus 로고    scopus 로고
    • Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation
    • Heard E, Rougeulle C, Arnaud D, Avner P, Allis CD, Spector DL. Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation. Cell 2001, 107:727–738.
    • (2001) Cell , vol.107 , pp. 727-738
    • Heard, E.1    Rougeulle, C.2    Arnaud, D.3    Avner, P.4    Allis, C.D.5    Spector, D.L.6
  • 58
    • 33646942973 scopus 로고    scopus 로고
    • The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation
    • Kalantry S, Magnuson T. The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. PLoS Genet 2006, 2:e66.
    • (2006) PLoS Genet , vol.2
    • Kalantry, S.1    Magnuson, T.2
  • 61
    • 79955441928 scopus 로고    scopus 로고
    • Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells
    • Casanova M, Preissner T, Cerase A, Poot R, Yamada D, Li X, Appanah R, Bezstarosti K, Demmers J, Koseki H, et al. Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells. Development 2011, 138:1471–1482.
    • (2011) Development , vol.138 , pp. 1471-1482
    • Casanova, M.1    Preissner, T.2    Cerase, A.3    Poot, R.4    Yamada, D.5    Li, X.6    Appanah, R.7    Bezstarosti, K.8    Demmers, J.9    Koseki, H.10
  • 63
    • 84947018503 scopus 로고    scopus 로고
    • Identification of Spen as a crucial factor for Xist function through forward genetic screening in haploid embryonic stem cells
    • Monfort A, Di Minin G, Postlmayr A, Freimann R, Arieti F, Thore S, Wutz A. Identification of Spen as a crucial factor for Xist function through forward genetic screening in haploid embryonic stem cells. Cell Rep 2015, 12:554–561.
    • (2015) Cell Rep , vol.12 , pp. 554-561
    • Monfort, A.1    Di Minin, G.2    Postlmayr, A.3    Freimann, R.4    Arieti, F.5    Thore, S.6    Wutz, A.7
  • 64
    • 33749177531 scopus 로고    scopus 로고
    • Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation
    • Savarese F, Flahndorfer K, Jaenisch R, Busslinger M, Wutz A. Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol 2006, 26:7167–7177.
    • (2006) Mol Cell Biol , vol.26 , pp. 7167-7177
    • Savarese, F.1    Flahndorfer, K.2    Jaenisch, R.3    Busslinger, M.4    Wutz, A.5
  • 66
    • 84867672345 scopus 로고    scopus 로고
    • Satb1 and Satb2 are dispensable for X chromosome inactivation in mice
    • Nechanitzky R, Davila A, Savarese F, Fietze S, Grosschedl R. Satb1 and Satb2 are dispensable for X chromosome inactivation in mice. Dev Cell 2012, 23:866–871.
    • (2012) Dev Cell , vol.23 , pp. 866-871
    • Nechanitzky, R.1    Davila, A.2    Savarese, F.3    Fietze, S.4    Grosschedl, R.5
  • 67
    • 0028212159 scopus 로고
    • The human X-inactivation centre is not required for maintenance of X-chromosome inactivation
    • Brown CJ, Willard HF. The human X-inactivation centre is not required for maintenance of X-chromosome inactivation. Nature 1994, 368:154–156.
    • (1994) Nature , vol.368 , pp. 154-156
    • Brown, C.J.1    Willard, H.F.2
  • 68
    • 0032805149 scopus 로고    scopus 로고
    • Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation [letter]
    • Csankovszki G, Panning B, Bates B, Pehrson JR, Jaenisch R. Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation [letter]. Nat Genet 1999, 22:323–324.
    • (1999) Nat Genet , vol.22 , pp. 323-324
    • Csankovszki, G.1    Panning, B.2    Bates, B.3    Pehrson, J.R.4    Jaenisch, R.5
  • 69
    • 34249006523 scopus 로고    scopus 로고
    • Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing
    • Zhang LF, Huynh KD, Lee JT. Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing. Cell 2007, 129:693–706.
    • (2007) Cell , vol.129 , pp. 693-706
    • Zhang, L.F.1    Huynh, K.D.2    Lee, J.T.3
  • 71
    • 0035858882 scopus 로고    scopus 로고
    • Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation
    • Csankovszki G, Nagy A, Jaenisch R. Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol 2001, 153:773–784.
    • (2001) J Cell Biol , vol.153 , pp. 773-784
    • Csankovszki, G.1    Nagy, A.2    Jaenisch, R.3
  • 73
    • 0022544604 scopus 로고
    • The relative intranuclear positions of Barr bodies in XXX non-transformed human fibroblasts
    • Belmont AS, Bignone F, Ts'o PO. The relative intranuclear positions of Barr bodies in XXX non-transformed human fibroblasts. Exp Cell Res 1986, 165:165–179.
    • (1986) Exp Cell Res , vol.165 , pp. 165-179
    • Belmont, A.S.1    Bignone, F.2    Ts'o, P.O.3
  • 77
    • 0942268864 scopus 로고    scopus 로고
    • Epigenetic dynamics of imprinted X inactivation during early mouse development
    • Okamoto I, Otte AP, Allis CD, Reinberg D, Heard E. Epigenetic dynamics of imprinted X inactivation during early mouse development. Science 2004, 303:644–649.
    • (2004) Science , vol.303 , pp. 644-649
    • Okamoto, I.1    Otte, A.P.2    Allis, C.D.3    Reinberg, D.4    Heard, E.5
  • 78
    • 0030880815 scopus 로고    scopus 로고
    • X chromosome inactivation is mediated by Xist RNA stabilization
    • Panning B, Dausman J, Jaenisch R. X chromosome inactivation is mediated by Xist RNA stabilization. Cell 1997, 90:907–916.
    • (1997) Cell , vol.90 , pp. 907-916
    • Panning, B.1    Dausman, J.2    Jaenisch, R.3
  • 81
    • 0030856414 scopus 로고    scopus 로고
    • XIST expression from the maternal X chromosome in human male preimplantation embryos at the blastocyst stage
    • Ray PF, Winston RM, Handyside AH. XIST expression from the maternal X chromosome in human male preimplantation embryos at the blastocyst stage. Hum Mol Genet 1997, 6:1323–1327.
    • (1997) Hum Mol Genet , vol.6 , pp. 1323-1327
    • Ray, P.F.1    Winston, R.M.2    Handyside, A.H.3
  • 83
    • 84930613787 scopus 로고    scopus 로고
    • X-chromosome inactivation: new insights into cis and trans regulation
    • Galupa R, Heard E. X-chromosome inactivation: new insights into cis and trans regulation. Curr Opin Genet Dev 2015, 31:57–66.
    • (2015) Curr Opin Genet Dev , vol.31 , pp. 57-66
    • Galupa, R.1    Heard, E.2
  • 85
    • 80053994141 scopus 로고    scopus 로고
    • A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation
    • Spencer RJ, del Rosario BC, Pinter SF, Lessing D, Sadreyev RI, Lee JT. A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation. Genetics 2011, 189:441–454.
    • (2011) Genetics , vol.189 , pp. 441-454
    • Spencer, R.J.1    del Rosario, B.C.2    Pinter, S.F.3    Lessing, D.4    Sadreyev, R.I.5    Lee, J.T.6
  • 90
    • 0036993322 scopus 로고    scopus 로고
    • Enox, a novel gene that maps 10 kb upstream of Xist and partially escapes X inactivation
    • Johnston CM, Newall AE, Brockdorff N, Nesterova TB. Enox, a novel gene that maps 10 kb upstream of Xist and partially escapes X inactivation. Genomics 2002, 80:236–244.
    • (2002) Genomics , vol.80 , pp. 236-244
    • Johnston, C.M.1    Newall, A.E.2    Brockdorff, N.3    Nesterova, T.B.4
  • 91
    • 77958472025 scopus 로고    scopus 로고
    • The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation
    • Tian D, Sun S, Lee JT. The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. Cell 2010, 143:390–403.
    • (2010) Cell , vol.143 , pp. 390-403
    • Tian, D.1    Sun, S.2    Lee, J.T.3
  • 93
    • 78751698195 scopus 로고    scopus 로고
    • Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region
    • Chureau C, Chantalat S, Romito A, Galvani A, Duret L, Avner P, Rougeulle C. Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. Hum Mol Genet 2011, 20:705–718.
    • (2011) Hum Mol Genet , vol.20 , pp. 705-718
    • Chureau, C.1    Chantalat, S.2    Romito, A.3    Galvani, A.4    Duret, L.5    Avner, P.6    Rougeulle, C.7
  • 95
    • 84902094525 scopus 로고    scopus 로고
    • Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos
    • Soma M, Fujihara Y, Okabe M, Ishino F, Kobayashi S. Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos. Sci Rep 2014, 4:5181.
    • (2014) Sci Rep , vol.4 , pp. 5181
    • Soma, M.1    Fujihara, Y.2    Okabe, M.3    Ishino, F.4    Kobayashi, S.5
  • 96
    • 84896403930 scopus 로고    scopus 로고
    • The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing
    • Barakat TS, Loos F, van Staveren S, Myronova E, Ghazvini M, Grootegoed JA, Gribnau J. The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing. Mol Cell 2014, 53:965–978.
    • (2014) Mol Cell , vol.53 , pp. 965-978
    • Barakat, T.S.1    Loos, F.2    van Staveren, S.3    Myronova, E.4    Ghazvini, M.5    Grootegoed, J.A.6    Gribnau, J.7
  • 100
    • 0031832579 scopus 로고    scopus 로고
    • Role of the region 3′ to Xist exon 6 in the counting process of X-chromosome inactivation
    • Clerc P, Avner P. Role of the region 3′ to Xist exon 6 in the counting process of X-chromosome inactivation. Nat Genet 1998, 19:249–253.
    • (1998) Nat Genet , vol.19 , pp. 249-253
    • Clerc, P.1    Avner, P.2
  • 101
    • 0035875043 scopus 로고    scopus 로고
    • Tsix-mediated repression of Xist accumulation is not sufficient for normal random X inactivation
    • Morey C, Arnaud D, Avner P, Clerc P. Tsix-mediated repression of Xist accumulation is not sufficient for normal random X inactivation. Hum Mol Genet 2001, 10:1403–1411.
    • (2001) Hum Mol Genet , vol.10 , pp. 1403-1411
    • Morey, C.1    Arnaud, D.2    Avner, P.3    Clerc, P.4
  • 102
    • 0032932528 scopus 로고    scopus 로고
    • Tsix, a gene antisense to Xist at the X-inactivation centre
    • Lee JT, Davidow LS, Warshawsky D. Tsix, a gene antisense to Xist at the X-inactivation centre. Nat Genet 1999, 21:400–404.
    • (1999) Nat Genet , vol.21 , pp. 400-404
    • Lee, J.T.1    Davidow, L.S.2    Warshawsky, D.3
  • 103
    • 0034730332 scopus 로고    scopus 로고
    • Disruption of imprinted X inactivation by parent-of-origin effects at Tsix
    • Lee JT. Disruption of imprinted X inactivation by parent-of-origin effects at Tsix. Cell 2000, 103:17–27.
    • (2000) Cell , vol.103 , pp. 17-27
    • Lee, J.T.1
  • 104
    • 0033214928 scopus 로고    scopus 로고
    • Targeted mutagenesis of Tsix leads to nonrandom X inactivation
    • Lee JT, Lu N. Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell 1999, 99:47–57.
    • (1999) Cell , vol.99 , pp. 47-57
    • Lee, J.T.1    Lu, N.2
  • 105
    • 0035197920 scopus 로고    scopus 로고
    • Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells
    • Luikenhuis S, Wutz A, Jaenisch R. Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells. Mol Cell Biol 2001, 21:8512–8520.
    • (2001) Mol Cell Biol , vol.21 , pp. 8512-8520
    • Luikenhuis, S.1    Wutz, A.2    Jaenisch, R.3
  • 106
    • 0035964420 scopus 로고    scopus 로고
    • A functional role for Tsix transcription in blocking Xist RNA accumulation but not in X-chromosome choice
    • Stavropoulos N, Lu N, Lee JT. A functional role for Tsix transcription in blocking Xist RNA accumulation but not in X-chromosome choice. Proc Natl Acad Sci 2001, 98:10232–10237.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 10232-10237
    • Stavropoulos, N.1    Lu, N.2    Lee, J.T.3
  • 107
    • 84929951270 scopus 로고    scopus 로고
    • A primary role for the Tsix lncRNA in maintaining random x-chromosome inactivation
    • Gayen S, Maclary E, Buttigieg E, Hinten M, Kalantry S. A primary role for the Tsix lncRNA in maintaining random x-chromosome inactivation. Cell Rep 2015, 11:1251–1265.
    • (2015) Cell Rep , vol.11 , pp. 1251-1265
    • Gayen, S.1    Maclary, E.2    Buttigieg, E.3    Hinten, M.4    Kalantry, S.5
  • 108
    • 0035030004 scopus 로고    scopus 로고
    • Regulation of imprinted X-chromosome inactivation in mice by Tsix
    • Sado T, Wang Z, Sasaki H, Li E. Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development 2001, 128:1275–1286.
    • (2001) Development , vol.128 , pp. 1275-1286
    • Sado, T.1    Wang, Z.2    Sasaki, H.3    Li, E.4
  • 111
    • 33751114695 scopus 로고    scopus 로고
    • Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xist promoter determines the Xist transcription program
    • Navarro P, Page DR, Avner P, Rougeulle C. Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xist promoter determines the Xist transcription program. Genes Dev 2006, 20:2787–2792.
    • (2006) Genes Dev , vol.20 , pp. 2787-2792
    • Navarro, P.1    Page, D.R.2    Avner, P.3    Rougeulle, C.4
  • 112
    • 22344451854 scopus 로고    scopus 로고
    • Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation
    • Navarro P, Pichard S, Ciaudo C, Avner P, Rougeulle C. Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation. Genes Dev 2005, 19:1474–1484.
    • (2005) Genes Dev , vol.19 , pp. 1474-1484
    • Navarro, P.1    Pichard, S.2    Ciaudo, C.3    Avner, P.4    Rougeulle, C.5
  • 113
    • 21344460496 scopus 로고    scopus 로고
    • Tsix silences Xist through modification of chromatin structure
    • Sado T, Hoki Y, Sasaki H. Tsix silences Xist through modification of chromatin structure. Dev Cell 2005, 9:159–165.
    • (2005) Dev Cell , vol.9 , pp. 159-165
    • Sado, T.1    Hoki, Y.2    Sasaki, H.3
  • 114
    • 45549098196 scopus 로고    scopus 로고
    • Intersection of the RNA interference and X-inactivation pathways
    • Ogawa Y, Sun BK, Lee JT. Intersection of the RNA interference and X-inactivation pathways. Science 2008, 320:1336–1341.
    • (2008) Science , vol.320 , pp. 1336-1341
    • Ogawa, Y.1    Sun, B.K.2    Lee, J.T.3
  • 117
    • 0037439284 scopus 로고    scopus 로고
    • Characterization and quantitation of differential Tsix transcripts: implications for Tsix function
    • Shibata S, Lee JT. Characterization and quantitation of differential Tsix transcripts: implications for Tsix function. Hum Mol Genet 2003, 12:125–136.
    • (2003) Hum Mol Genet , vol.12 , pp. 125-136
    • Shibata, S.1    Lee, J.T.2
  • 118
    • 38949194937 scopus 로고    scopus 로고
    • Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification
    • Ohhata T, Hoki Y, Sasaki H, Sado T. Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification. Development 2008, 135:227–235.
    • (2008) Development , vol.135 , pp. 227-235
    • Ohhata, T.1    Hoki, Y.2    Sasaki, H.3    Sado, T.4
  • 119
    • 4644223587 scopus 로고    scopus 로고
    • Tsix transcription-versus RNA-based mechanisms in Xist repression and epigenetic choice
    • Shibata S, Lee JT. Tsix transcription-versus RNA-based mechanisms in Xist repression and epigenetic choice. Curr Biol 2004, 14:1747–1754.
    • (2004) Curr Biol , vol.14 , pp. 1747-1754
    • Shibata, S.1    Lee, J.T.2
  • 121
    • 0037349309 scopus 로고    scopus 로고
    • Xite, X-inactivation intergenic transcription elements that regulate the probability of choice
    • Ogawa Y, Lee JT. Xite, X-inactivation intergenic transcription elements that regulate the probability of choice. Mol Cell 2003, 11:731–743.
    • (2003) Mol Cell , vol.11 , pp. 731-743
    • Ogawa, Y.1    Lee, J.T.2
  • 122
    • 84455206362 scopus 로고    scopus 로고
    • Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
    • Ulitsky I, Shkumatava A, Jan CH, Sive H, Bartel DP. Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell 2011, 147:1537–1550.
    • (2011) Cell , vol.147 , pp. 1537-1550
    • Ulitsky, I.1    Shkumatava, A.2    Jan, C.H.3    Sive, H.4    Bartel, D.P.5
  • 123
    • 81155159786 scopus 로고    scopus 로고
    • Origin and evolution of the long non-coding genes in the X-inactivation center
    • Romito A, Rougeulle C. Origin and evolution of the long non-coding genes in the X-inactivation center. Biochimie 2011, 93:1935–1942.
    • (2011) Biochimie , vol.93 , pp. 1935-1942
    • Romito, A.1    Rougeulle, C.2
  • 124
    • 0034757204 scopus 로고    scopus 로고
    • Identification of TSIX, encoding an RNA antisense to human XIST, reveals differences from its murine counterpart: implications for X inactivation
    • Migeon BR, Chowdhury AK, Dunston JA, McIntosh I. Identification of TSIX, encoding an RNA antisense to human XIST, reveals differences from its murine counterpart: implications for X inactivation. Am J Hum Genet 2001, 69:951–960.
    • (2001) Am J Hum Genet , vol.69 , pp. 951-960
    • Migeon, B.R.1    Chowdhury, A.K.2    Dunston, J.A.3    McIntosh, I.4
  • 125
    • 0036073860 scopus 로고    scopus 로고
    • Species differences in TSIX/Tsix reveal the roles of these genes in X-chromosome inactivation
    • Migeon BR, Lee CH, Chowdhury AK, Carpenter H. Species differences in TSIX/Tsix reveal the roles of these genes in X-chromosome inactivation. Am J Hum Genet 2002, 71:286–293.
    • (2002) Am J Hum Genet , vol.71 , pp. 286-293
    • Migeon, B.R.1    Lee, C.H.2    Chowdhury, A.K.3    Carpenter, H.4
  • 126
    • 80053444842 scopus 로고    scopus 로고
    • Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain
    • Anguera MC, Ma W, Clift D, Namekawa S, Kelleher RJ 3rd, Lee JT. Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain. PLoS Genet 2011, 7:e1002248.
    • (2011) PLoS Genet , vol.7
    • Anguera, M.C.1    Ma, W.2    Clift, D.3    Namekawa, S.4    Kelleher, R.J.5    Lee, J.T.6
  • 127
    • 0032534876 scopus 로고    scopus 로고
    • The mouse Tsx gene is expressed in Sertoli cells of the adult testis and transiently in premeiotic germ cells during puberty
    • Cunningham DB, Segretain D, Arnaud D, Rogner UC, Avner P. The mouse Tsx gene is expressed in Sertoli cells of the adult testis and transiently in premeiotic germ cells during puberty. Dev Biol 1998, 204:345–360.
    • (1998) Dev Biol , vol.204 , pp. 345-360
    • Cunningham, D.B.1    Segretain, D.2    Arnaud, D.3    Rogner, U.C.4    Avner, P.5
  • 129
    • 84861095603 scopus 로고    scopus 로고
    • Topological domains in mammalian genomes identified by analysis of chromatin interactions
    • Dixon JR, Selvaraj S, Yue F, Kim A, Li Y, Shen Y, Hu M, Liu JS, Ren B. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 2012, 485:376–380.
    • (2012) Nature , vol.485 , pp. 376-380
    • Dixon, J.R.1    Selvaraj, S.2    Yue, F.3    Kim, A.4    Li, Y.5    Shen, Y.6    Hu, M.7    Liu, J.S.8    Ren, B.9
  • 133
    • 0015240843 scopus 로고
    • Late DNA replication in the paternally derived X chromosome of female kangaroos
    • Sharman GB. Late DNA replication in the paternally derived X chromosome of female kangaroos. Nature 1971, 230:231–232.
    • (1971) Nature , vol.230 , pp. 231-232
    • Sharman, G.B.1
  • 134
    • 0023408235 scopus 로고
    • DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation
    • Kaslow DC, Migeon BR. DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation. Proc Natl Acad Sci U S A 1987, 84:6210–6214.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 6210-6214
    • Kaslow, D.C.1    Migeon, B.R.2
  • 135
    • 79955567395 scopus 로고    scopus 로고
    • Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals
    • Chaumeil J, Waters PD, Koina E, Gilbert C, Robinson TJ, Graves JA. Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals. PLoS One 2011, 6:e19040.
    • (2011) PLoS One , vol.6
    • Chaumeil, J.1    Waters, P.D.2    Koina, E.3    Gilbert, C.4    Robinson, T.J.5    Graves, J.A.6
  • 139
    • 84891706153 scopus 로고    scopus 로고
    • Chromosome-wide profiling of X-chromosome inactivation and epigenetic states in fetal brain and placenta of the opossum, Monodelphis domestica
    • Wang X, Douglas KC, Vandeberg JL, Clark AG, Samollow PB. Chromosome-wide profiling of X-chromosome inactivation and epigenetic states in fetal brain and placenta of the opossum, Monodelphis domestica. Genome Res 2014, 24:70–83.
    • (2014) Genome Res , vol.24 , pp. 70-83
    • Wang, X.1    Douglas, K.C.2    Vandeberg, J.L.3    Clark, A.G.4    Samollow, P.B.5


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