Species differences in TSIX/Tsix reveal the roles of these genes in X-chromosome inactivation

American Journal of Human Genetics

Volumn 71, Issue 2, 2002, Pages 286-293

  Migeon, Barbara R ^a   Lee, Catherine H ^a   Chowdhury, Ashis K ^a   Carpenter, Heather ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CELL PROTECTION; EMBRYO DEVELOPMENT; GENE REPRESSION; GENE SILENCING; GENETIC ANALYSIS; GENOME IMPRINTING; HUMAN; HUMAN CELL; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE; TRANSCRIPTION REGULATION; X CHROMOSOME INACTIVATION;

MURINAE;

EID: 0036073860     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/341605     Document Type: Article

References (35)

1. PNA interference mapping demonstrates functional domains in the noncoding RNA Xist
2. Forty years of decoding the silence in X-chromosome inactivation
3. The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus
4. The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
5. CTCF, a candidate trans-acting factor for X-inactivation
6. RNA paints the inactive X chromosome at interphase: Evidence for a novel RNA involved in nuclear/chromosome structure
7. Functional analysis of the DXPas34 locus, a 3′ regulator of Xist expression
8. Late replicating X chromosomes in human triploidy
9. Studies of X-chromosome inactivation in trisomies
10. Mechanisms of origin of complete hydatidiform moles
11. The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation
12. Disruption of imprinted X inactivation by parent-of-origin-effects at Tsix
13. Tsix, a gene antisense to Xist at the X-inactivation centre
14. Targeted Mutagenesis of Tsix leads to nonrandom inactivation
15. A 450 kb transgene displays properties of the mammalian X-inactivation center
16. Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells
17. Sex chromatin and gene action in the mammalian X-chromosome
18. Possible mechanisms of X chromosome inactivation
19. Xist-deficient mice are defective in dosage compensation but not spermatogenesis
20. X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro
21. Identification of TSIX encoding an RNA antisense to human XIST, reveals differences from its murine counterpart: Implications for X inactivation
22. In search of non-random X inactivation: Studies of fetal membranes heterozygous for glucose-6-phosphate dehydrogenase
23. Human X inactivation center induces random X inactivation in male transgenic mice
24. Stability of the "two active X" phenotype in triploid cells
25. Incomplete X dosage compensation in chorionic villi of human placenta
26. Tsix-mediated repression of Xist accumulation is not sufficient for normal random X inactivation
27. Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain
28. Requirements for Xist in X chromosome inactivation
29. Regulation of imprinted X-chromosome inactivation in mice by Tsix
30. Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro
31. A functional role for Tsix transcription in blocking RNA accumulation but not in X-chromosomal choice
32. Detrimental effects of two active X chromosomes on early mouse development
33. Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse
34. Evidence for two active X chromosomes in a human XXY triploid
35. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation