Erosion of dosage compensation impacts human iPSC disease modeling

Cell Stem Cell

Volumn 10, Issue 5, 2012, Pages 595-609

  Mekhoubad, Shila ^a,b   Bock, Christoph ^a,c,d   De Boer, A Sophie ^a,b,e   Kiskinis, Evangelos ^a,b   Meissner, Alexander ^a,c   Eggan, Kevin ^a,b  

^a Harvard University   (United States)

^b HARVARD UNIVERSITY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d MAX PLANCK INSTITUTE FOR INFORMATICS   (Germany)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CULTURE; CHROMOSOME INACTIVATION; CONTROLLED STUDY; DISEASE MODEL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LESCH NYHAN SYNDROME; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SOMATIC CELL; X CHROMOSOME;

CELLS, CULTURED; CHROMOSOMES, HUMAN, X; DNA METHYLATION; DOSAGE COMPENSATION, GENETIC; FEMALE; GENOMIC INSTABILITY; HISTONES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LESCH-NYHAN SYNDROME; MODELS, BIOLOGICAL; RNA, UNTRANSLATED;

EID: 84860640679     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.02.014     Document Type: Article

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