A 450 kb transgene displays properties of the mammalian X-inactivation center

Cell

Volumn 86, Issue 1, 1996, Pages 83-94

  Lee, Jeannie T ^a,b   Strauss, William M ^b   Dausman, Jessica A ^a   Jaenisch, Rudolf ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; AUTOSOME; CELL DEATH; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE EXPRESSION REGULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; X CHROMOSOME INACTIVATION;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0030581152     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80079-3     Document Type: Article

References (42)

1. Assaad, F.F., Tucker, K.L., and Signer, E.R (1993). Epigenetic repeat-induced gene silencing (RIGS) in Arabidopsis. Plant Mol. Biol. 22, 1067-1085.
2. Barr, M.L., and Carr, D.H. (1962). Correlations between sex chromatin and sex chromosomes. Acta Cytol. 6, 34-45.
3. Beard, C., Li, E., and Jaenisch, J. (1995). Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev. 9, 2325-2334.
4. Belmont, A.S., Bignone, F., and Ts'o, P.O.P. (1986). The relative intranuclear positions of Barr bodies in XXX non-transformed human fibroblasts. Exp. Cell Res. 165, 165-179.
5. Borsani, G., Tonlorenzi, R., Simmler, M.C., Dandolo, L., Arnaud, D., Capra, V., Grompe, M., Pizzuti, A., Muzny, D., Lawrence, C., Willard, H.F., Avner, P., and Ballabio, A. (1991). Characterization of a murine gene expressed from the inactive X chromosome. Nature 351, 325-328.
6. Brockdorff, N., Ashworth, A., Kay, G.F., Cooper, P., Smith, S., McCabe, V.M., Morris, D.P., Penny, G.D., Patel, D., and Rastan, S. (1991). Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 351, 329-331.
7. Brown, C.J., Ballabio, A., Rupert, J.L., Lafreniere, R.G., Grompe, M., Tonlorenzi, R., and Willard, H. (1991). A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 349, 38-44.
8. Cattanach, B.M. (1974). Position effect variegation in the mouse. Genet. Res. 23, 291-306.
9. Chuang, P.-T., Albertson, D.G., and Meyer, B.J. (1994). DPY-27: a chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome. Cell 79, 459-474.
10. Clemson, C.M., McNeil, J.A., Willard, H., and Lawrence, J.B. (1996). XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J. Cell Biol. 132, 1-17.
11. Cooper, P., Keer, J.T., McCabe, V.M., Hamvas, R.M.J., Brown, S.D.M., Rastan, S., and Brockdorff, N. (1993). Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus. Genomics 15, 570-575.
12. Coucouvanis, E., and Martin, G.R. (1995). Signals for death and survival: a two-step mechanism for cavitation in the vertebrate embryo. Cell 83, 279-287.
13. Courtier, B., Heard, E., and Avner, P. (1995). Xce haplotypes show modified methylation in a region of the active X-chromosome lying 3′ to Xist. Proc. Natl. Acad. Sci. USA 92, 3531-3535.
14. Dorer, D.R., and Henikoff, S. (1994). Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila. Cell 77, 993-1002.
15. Friedrich, G., and Soriano, P. (1991). Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5, 1513-1523.
16. Gardner, H., Kreidberg, J., Koteliansky, V., and Jaenisch, R. (1996). Deletion of integrin α1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. Dev. Biol., 175, 301-313.
17. Graves, J.A.M., and Gartler, S.M. (1986). Mammalian X chromosome inactivation: testing the hypothesis of transcriptional control. Somat. Cell Mol. Genet. 12, 275-280.
18. Heard, E., Simmler, M.-C., Larin, Z., Rougeulle, C., Courtier, B., Lehrach, H., and Avner, P. (1993). Physical mapping and YAC contig analysis of the region surrounding Xist on the mouse X chromosome. Genomics 15, 559-569.
19. Heard, E., Kress, C., Mongelard, F., Courtier, B., Rougeulle, C., Ashworth, A., Vourch, C., Babinet, C., and Avner, P. (1996). Transgenic mice carrying an Xist-containing YAC. Hum. Mol. Genet. 5, 441-450.
20. Jat, P.S., Cepko, C.L., Mulligan, R.C., and Sharp, P.A. (1986). Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Mol. Cell. Biol. 6, 1204-1217.
21. Kay, G.F., Penny, G.D., Patel, D., Ashworth, A., Brockdorff, N., and Rastan, S. (1993). Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell 72, 171-182.
22. Kelley, R.L., and Kuroda, M.I. (1995). Equality of X chromosomes. Science 270, 1607-1610.
23. Kusumi, K., Smith, J.S., Segre, J.A., Koos, D.S., and Lander, E.S. (1993). Construction of a large-insert yeast artificial chromosome library of the mouse genome. Mamm. Genome 4, 391-392.
24. Lawrence, J.B., Singer, R.H., and Marselle, L.M. (1989). Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization. Cell 57, 493-502.
25. Lee, J.T., Murgia, A., Sosnoski, D.M., Olivos, I.M., and Nussbaum, R.L. (1992). Construction and characterization of a yeast artificial chromosome library for Xpter-Xq27.3: a systematic determination of cocloning rate and X-chromosome representation. Genomics 12, 526-533.
26. Leppig, K.A., Brown, C.J., Bressler, S.L., Gustashaw, K., Pagon, R.A., Willard, H., and Disteche, C. (1993). Mapping of the distal boundary of the X-inactivation center in a rearranged X chromosome from a female expressing XIST. Hum. Mol. Genet. 2, 883-887.
27. Li, E., Bestor, T.H., and Jaenisch, R. (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
28. Lyon, M.F. (1961). Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature 190, 372-373.
29. Martin, G.R., and Evans, M.J. (1975). Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. Proc. Natl. Acad. Sci. USA 72, 1441-1445.
30. Martin, G.R., Epstein, C.J., Travis, B., Tucker, G., Yatziv, S., David, J., Martin, W., Clift, S., and Cohen, S. (1978). X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro. Nature 277, 329-333.
31. Matsuura, S., Episkopou, V., Hamvas, R., and Brown, S.D.M. (1996). Xist expression from an Xist YAC transgene carried on the mouse Y chromosome. Hum. Mol. Genet. 5, 451-459.
32. McGahon, A.J., Martin, S.J., Bissonnette, R.P., Mahboubi, A., Shi, Y., Mogil, R.J., Nishioka, W.K., and Green, D.R. (1995). The end of the (cell) line: methods for the study of apoptosis in vitro. In Cell Death, L.M. Schwartz and B.A. Osborne, eds. (San Diego, California: Academic Press), pp. 153-185.
33. Migeon, B.R. (1994). X-chromosome inactivation: molecular mechanisms and genetic consequences. Trends Genet. 10, 230-235.
34. Parkhurst, S.M., and Meneely, P.M. (1994). Sex determination and dosage compensation: lessons from flies and worms. Science 264, 924-932.
35. Penny, G.D., Kay, G.F., Sheardown, S.A., Rastan, S., and Brockdorff, N. (1996). Requirement for Xist in X chromosome inactivation. Nature 379, 131-137.
36. Rastan, S., and Brown, S.D.M. (1990). The search for the mouse X-chromosome inactivation centre. Genet. Res. 56, 99-106.
37. Rastan, S., and Robertson, E.J. (1985). X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation. J. Embryol. Exp. Morphol. 90, 379-388.
38. Russell, L.B. (1963). Mammalian X-chromosome action: inactivation limited in spread and in region of origin. Science 140, 976-978.
39. Simmler, M.-C., Cattanach, B.M., Rasberry, C., Rougeulle, C., and Avner, P. (1993). Mapping the murine Xce locus with (CA)n repeats. Mamm. Genome 4, 523-530.
40. Strauss, W.M., Dausman, J., Beard, G., Johnson, C., Lawrence, J., and Jaenisch, R. (1993). Germ line transmission of a yeast artificial chromosome spanning the murine α1(I) collagen locus. Science 259, 1904-1907.
41. Tai, H.H., Gordon, J., and McBurney, M.W. (1994). Xist is expressed in female embryonal carcinoma cells with two active X chromosomes. Somat. Cell Mol. Genet. 20, 171-182.
42. Trask, B.J. (1991). Fluorescence in situ hybridization. Trends Genet. 7, 149-154.