Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation

eLife

Volumn 5, Issue APRIL2016, 2016, Pages

  Ishimura, Ryuta ^a   Nagy, Gabor ^a   Dotu, Ivan ^b   Chuang, Jeffrey H ^c,d   Ackerman, Susan L ^a,e,f  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c JACKSON LABORATORY   (United States)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NEUROBIOLOGY SECTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ARGININE TRANSFER RNA; ATF4 PROTEIN, MOUSE; EIF2AK4 PROTEIN, MOUSE; GTPBP2 PROTEIN, MOUSE; GUANINE NUCLEOTIDE BINDING PROTEIN; INITIATION FACTOR 2; PROTEIN SERINE THREONINE KINASE;

AMINOACYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FRAGILE X SYNDROME; GENE MUTATION; GENE ONTOLOGY; GENE OVEREXPRESSION; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; MALE; MICROARRAY ANALYSIS; MOUSE; NERVE DEGENERATION; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION ELONGATION; TRANSLATION INITIATION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DEFICIENCY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; RIBOSOME; TRANSLATION ELONGATION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION PROFILING; GTP-BINDING PROTEINS; MICE, INBRED C57BL; NEURONS; PEPTIDE CHAIN ELONGATION, TRANSLATIONAL; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMES; RNA, TRANSFER, ARG;

EID: 84979583000     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.14295     Document Type: Article

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