Crystal structures of GCN2 protein kinase C-terminal domains suggest regulatory differences in yeast and mammals

Journal of Biological Chemistry

Volumn 289, Issue 21, 2014, Pages 15023-15034

  He, Hongzhen ^a   Singh, Isha ^a   Wek, Sheree A ^a   Dey, Souvik ^a   Baird, Thomas D ^a   Wek, Ronald C ^a   Georgiadis, Millie M ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CRYSTAL STRUCTURE; ENZYMES; MAMMALS; PLANTS (BOTANY); PROTEINS; RNA;

AMINO ACID STARVATIONS; C-TERMINAL DOMAINS; DOUBLE-STRANDED RNA; GENERAL TRANSLATION; HIGH RESOLUTION CRYSTAL STRUCTURE; MULTIDOMAIN PROTEINS; NUTRIENT LIMITATIONS; STRUCTURAL DIFFERENCES;

YEAST;

DOUBLE STRANDED RNA; INITIATION FACTOR 2; PROTEIN GCN2; PROTEIN KINASE C; SINGLE STRANDED RNA; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIMERIZATION; ENZYME ANALYSIS; ENZYME REGULATION; ENZYME STRUCTURE; MOLECULAR STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN RNA BINDING; RIBOSOME; SEQUENCE HOMOLOGY; TRANSLATION REGULATION; YEAST;

C-TERMINAL DOMAIN; CRYSTAL STRUCTURE; EIF2 KINASE; GCN2; PROTEIN DOMAINS; PROTEIN-NUCLEIC ACID INTERACTION; STRESS; TRANSLATION REGULATION;

ANIMALS; CELLS, CULTURED; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; EMBRYO, MAMMALIAN; FIBROBLASTS; IMMUNOBLOTTING; MICE; MICE, KNOCKOUT; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RNA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84901393610     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.560789     Document Type: Article

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