Deletion of the eIF2α Kinase GCN2 Fails to Rescue the Memory Decline Associated with Alzheimer's Disease

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Devi, Latha ^a   Ohno, Masuo ^a,b  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; AMYLOID BETA PROTEIN; BETA SECRETASE 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GENERAL CONTROL NONDEREPRESSIBLE 2 KINASE; INITIATION FACTOR 2ALPHA; PKR ENDOPLASMIC RETICULUM RELATED KINASE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; KNOCKOUT MOUSE; MEMORY DISORDER; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE;

ACTIVATING TRANSCRIPTION FACTOR 4; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DISEASE MODELS, ANIMAL; EIF-2 KINASE; GENE DELETION; GENOTYPE; HUMANS; MEMORY DISORDERS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 84885398154     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077335     Document Type: Article

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