Revealing an outward-facing open conformational state in a CLC CL-/H+ exchange transporter

eLife

Volumn 5, Issue JANUARY2016, 2016, Pages

  Khantwal, Chandra M ^a   Abraham, Sherwin J ^a   Han, Wei ^b,c   Jiang, Tao ^b,c   Chavan, Tanmay S ^a   Cheng, Ricky C ^a   Elvington, Shelley M ^a   Liu, Corey W ^a   Mathews, Irimpan I ^d   Stein, Richard A ^e   McHaourab, Hassane S ^e   Tajkhorshid, Emad ^b,c   Maduke, Merritt ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL PROTON CHLORIDE EXCHANGE TRANSPORTER; MEMBRANE PROTEIN; TEMPOL; UNCLASSIFIED DRUG; CHLORIDE CHANNEL; CLC PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; DISULFIDE BOND; FLUORINE NUCLEAR MAGNETIC RESONANCE; GENE MUTATION; ISOTHERMAL TITRATION CALORIMETRY; MEMBRANE PERMEABILITY; MOLECULAR DYNAMICS; PH; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; SIZE EXCLUSION CHROMATOGRAPHY; STOICHIOMETRY; CHEMISTRY; ELECTRON SPIN RESONANCE; METABOLISM; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

CHLORIDE CHANNELS; CRYSTALLOGRAPHY, X-RAY; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION;

EID: 84979547129     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11189     Document Type: Article

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