-
1
-
-
0014029736
-
Simple allosteric model for membrane pumps
-
Jardetzky, O. Simple allosteric model for membrane pumps. Nature 211, 969-970 (1966).
-
(1966)
Nature
, vol.211
, pp. 969-970
-
-
Jardetzky, O.1
-
2
-
-
0024534816
-
Structure and function of the red blood cell anion transport protein
-
Jennings, M.L. Structure and function of the red blood cell anion transport protein. Annu. Rev. Biophys. Biophys. Chem. 18, 397-430 (1989).
-
(1989)
Annu. Rev. Biophys. Biophys. Chem.
, vol.18
, pp. 397-430
-
-
Jennings, M.L.1
-
3
-
-
34547902820
-
Mechanism of Na +H+ antiporting
-
Arkin, I.T. et al. Mechanism of Na +H+ antiporting. Science 317, 799-803 (2007).
-
(2007)
Science
, vol.317
, pp. 799-803
-
-
Arkin, I.T.1
-
4
-
-
60549097035
-
Alternating access in maltose transporter mediated by rigid-body rotations
-
Khare, D., Oldham, M.L., Orelle, C., Davidson, A.L. & Chen, J. Alternating access in maltose transporter mediated by rigid-body rotations. Mol. Cell 33, 528-536 (2009).
-
(2009)
Mol. Cell
, vol.33
, pp. 528-536
-
-
Khare, D.1
Oldham, M.L.2
Orelle, C.3
Davidson, A.L.4
Chen, J.5
-
5
-
-
77951585158
-
Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1
-
Shimamura, T. et al. Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1. Science 328, 470-473 (2010).
-
(2010)
Science
, vol.328
, pp. 470-473
-
-
Shimamura, T.1
-
6
-
-
79955662093
-
The alternating access transport mechanism in LacY
-
Kaback, H.R., Smirnova, I., Kasho, V., Nie, Y. & Zhou, Y. The alternating access transport mechanism in LacY. J. Membr. Biol. 239, 85-93 (2011).
-
(2011)
J. Membr. Biol.
, vol.239
, pp. 85-93
-
-
Kaback, H.R.1
Smirnova, I.2
Kasho, V.3
Nie, Y.4
Zhou, Y.5
-
7
-
-
79952738070
-
The alternating-access mechanism of MFS transporters arises from inverted-topology repeats
-
Radestock, S. & Forrest, L.R. The alternating-access mechanism of MFS transporters arises from inverted-topology repeats. J. Mol. Biol. 407, 698-715 (2011).
-
(2011)
J. Mol. Biol.
, vol.407
, pp. 698-715
-
-
Radestock, S.1
Forrest, L.R.2
-
8
-
-
0026653443
-
Ferret red cells: Na/Ca exchange and Na-K-Cl cotransport
-
Milanick, M.A. Ferret red cells: Na/Ca exchange and Na-K-Cl cotransport. Comp. Biochem. Physiol. Comp. Physiol. 102, 619-624 (1992).
-
(1992)
Comp. Biochem. Physiol. Comp. Physiol.
, vol.102
, pp. 619-624
-
-
Milanick, M.A.1
-
9
-
-
0028882542
-
A conserved glutamate is responsible for ion selectivity and pH dependence of the mammalian anion exchangers AE1 and AE2
-
Sekler, I., Lo, R.S. & Kopito, R.R. A conserved glutamate is responsible for ion selectivity and pH dependence of the mammalian anion exchangers AE1 and AE2. J. Biol. Chem. 270, 28751-28758 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28751-28758
-
-
Sekler, I.1
Lo, R.S.2
Kopito, R.R.3
-
10
-
-
60549109436
-
The squid axon Na +Ca2+ exchanger shows ping-pong kinetics only when the Cai-regulatory site is saturated
-
Beaugé, L. & DiPolo, R. The squid axon Na +Ca2+ exchanger shows ping-pong kinetics only when the Cai-regulatory site is saturated. Cell. Physiol. Biochem. 23, 37-42 (2009).
-
(2009)
Cell. Physiol. Biochem.
, vol.23
, pp. 37-42
-
-
Beaugé, L.1
Dipolo, R.2
-
11
-
-
36749095723
-
The fast release of sticky protons: Kinetics of substrate binding and proton release in a multidrug transporter
-
Adam, Y., Tayer, N., Rotem, D., Schreiber, G. & Schuldiner, S. The fast release of sticky protons: kinetics of substrate binding and proton release in a multidrug transporter. Proc. Natl. Acad. Sci. USA 104, 17989-17994 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17989-17994
-
-
Adam, Y.1
Tayer, N.2
Rotem, D.3
Schreiber, G.4
Schuldiner, S.5
-
12
-
-
0026496916
-
A novel method to differentiate between ping-pong and simultaneous exchange kinetics and its application to the anion exchanger of the HL60 cell
-
Restrepo, D., Cronise, B.L., Snyder, R.B. & Knauf, P.A. A novel method to differentiate between ping-pong and simultaneous exchange kinetics and its application to the anion exchanger of the HL60 cell. J. Gen. Physiol. 100, 825-846 (1992).
-
(1992)
J. Gen. Physiol.
, vol.100
, pp. 825-846
-
-
Restrepo, D.1
Cronise, B.L.2
Snyder, R.B.3
Knauf, P.A.4
-
13
-
-
17244376557
-
Evidence for simultaneous 1Na+:1Mg2+ and ping-pong 2Na+:1Mg2+ exchangers in rat thymocyte
-
Contreras-Jurado, C., Sanchez-Morito, N., Ruiz-Contreras, A., Gonzalez-Martinez, M.T. & Soler-Diaz, A. Evidence for simultaneous 1Na+:1Mg2+ and ping-pong 2Na+:1Mg2+ exchangers in rat thymocyte. Front. Biosci. 10, 1693-1706 (2005).
-
(2005)
Front. Biosci.
, vol.10
, pp. 1693-1706
-
-
Contreras-Jurado, C.1
Sanchez-Morito, N.2
Ruiz-Contreras, A.3
Gonzalez-Martinez, M.T.4
Soler-Diaz, A.5
-
14
-
-
0037122805
-
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
-
Dutzler, R., Campbell, E.B., Cadene, M., Chait, B.T. & MacKinnon, R. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity. Nature 415, 287-294 (2002).
-
(2002)
Nature
, vol.415
, pp. 287-294
-
-
Dutzler, R.1
Campbell, E.B.2
Cadene, M.3
Chait, B.T.4
MacKinnon, R.5
-
15
-
-
0041353145
-
Structure and mechanism of the lactose permease of Escherichia coli
-
Abramson, J. et al. Structure and mechanism of the lactose permease of Escherichia coli. Science 301, 610-615 (2003).
-
(2003)
Science
, vol.301
, pp. 610-615
-
-
Abramson, J.1
-
16
-
-
7244254186
-
Structure of a glutamate transporter homolog from Pyrococcus horikoshii
-
Yernool, D., Boudker, O., Jin, Y. & Gouaux, E. Structure of a glutamate transporter homolog from Pyrococcus horikoshii. Nature 431, 811-818 (2004).
-
(2004)
Nature
, vol.431
, pp. 811-818
-
-
Yernool, D.1
Boudker, O.2
Jin, Y.3
Gouaux, E.4
-
18
-
-
37249088547
-
Crystal structure of the sodium-potassium pump
-
Morth, J.P. et al. Crystal structure of the sodium-potassium pump. Nature 450, 1043-1049 (2007).
-
(2007)
Nature
, vol.450
, pp. 1043-1049
-
-
Morth, J.P.1
-
19
-
-
37249043376
-
The structural basis of calcium transport by the calcium pump
-
Olesen, C. et al. The structural basis of calcium transport by the calcium pump. Nature 450, 1036-1042 (2007).
-
(2007)
Nature
, vol.450
, pp. 1036-1042
-
-
Olesen, C.1
-
20
-
-
69249220125
-
Structure of a prokaryotic virtual proton pump at 3.2-Å resolution
-
Fang, Y. et al. Structure of a prokaryotic virtual proton pump at 3.2-Å resolution. Nature 460, 1040-1043 (2009).
-
(2009)
Nature
, vol.460
, pp. 1040-1043
-
-
Fang, Y.1
-
23
-
-
22944479662
-
Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins
-
Scheel, O., Zdebik, A.A., Lourdel, S. & Jentsch, T.J. Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature 436, 424-427 (2005).
-
(2005)
Nature
, vol.436
, pp. 424-427
-
-
Scheel, O.1
Zdebik, A.A.2
Lourdel, S.3
Jentsch, T.J.4
-
24
-
-
22944475536
-
Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5
-
Picollo, A. & Pusch, M. Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5. Nature 436, 420-423 (2005).
-
(2005)
Nature
, vol.436
, pp. 420-423
-
-
Picollo, A.1
Pusch, M.2
-
25
-
-
33747858034
-
The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles
-
De Angeli, A. et al. The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles. Nature 442, 939-942 (2006).
-
(2006)
Nature
, vol.442
, pp. 939-942
-
-
De Angeli, A.1
-
26
-
-
44849107047
-
+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes
-
+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes. Nature 453, 788 (2008).
-
(2008)
Nature
, vol.453
, pp. 788
-
-
Graves, A.R.1
Curran, P.2
Smith, C.3
Mindell, J.4
-
27
-
-
38349134206
-
Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent
-
Matsuda, J.J. et al. Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent. Am. J. Physiol. Cell Physiol. 294, C251-262 (2008).
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.294
-
-
Matsuda, J.J.1
-
29
-
-
78049362741
-
Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle
-
Feng, L., Campbell, E.B., Hsiung, Y. & MacKinnon, R. Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle. Science 330, 635-641 (2010).
-
(2010)
Science
, vol.330
, pp. 635-641
-
-
Feng, L.1
Campbell, E.B.2
Hsiung, Y.3
MacKinnon, R.4
-
30
-
-
39849105844
-
Determinants of anion-proton coupling in mammalian endosomal CLC proteins
-
Zdebik, A.A. et al. Determinants of anion-proton coupling in mammalian endosomal CLC proteins. J. Biol. Chem. 283, 4219-4227 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4219-4227
-
-
Zdebik, A.A.1
-
31
-
-
0037418859
-
Gating the selectivity filter in ClC chloride channels
-
Dutzler, R., Campbell, E.B. & MacKinnon, R. Gating the selectivity filter in ClC chloride channels. Science 300, 108-112 (2003).
-
(2003)
Science
, vol.300
, pp. 108-112
-
-
Dutzler, R.1
Campbell, E.B.2
MacKinnon, R.3
-
32
-
-
77953808359
-
CLC channels and transporters: Proteins with borderline personalities
-
Accardi, A. & Picollo, A. CLC channels and transporters: proteins with borderline personalities. Biochim. Biophys. Acta 1798, 1457-1464 (2010).
-
(2010)
Biochim. Biophys. Acta
, vol.1798
, pp. 1457-1464
-
-
Accardi, A.1
Picollo, A.2
-
33
-
-
77953555147
-
Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis
-
Novarino, G., Weinert, S., Rickheit, G. & Jentsch, T.J. Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis. Science 328, 1398-1401 (2010).
-
(2010)
Science
, vol.328
, pp. 1398-1401
-
-
Novarino, G.1
Weinert, S.2
Rickheit, G.3
Jentsch, T.J.4
-
34
-
-
0029832524
-
Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry
-
Baker, B.M. & Murphy, K.P. Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry. Biophys. J. 71, 2049-2055 (1996).
-
(1996)
Biophys. J.
, vol.71
, pp. 2049-2055
-
-
Baker, B.M.1
Murphy, K.P.2
-
35
-
-
0033997038
-
Contribution of proton linkage to the thermodynamic stability of the major cold-shock protein of Escherichia coli CspA
-
Petrosian, S.A. & Makhatadze, G.I. Contribution of proton linkage to the thermodynamic stability of the major cold-shock protein of Escherichia coli CspA. Protein Sci. 9, 387-394 (2000).
-
(2000)
Protein Sci.
, vol.9
, pp. 387-394
-
-
Petrosian, S.A.1
Makhatadze, G.I.2
-
36
-
-
0033815251
-
Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor
-
Velazquez-Campoy, A. et al. Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor. Protein Sci. 9, 1801-1809 (2000).
-
(2000)
Protein Sci.
, vol.9
, pp. 1801-1809
-
-
Velazquez-Campoy, A.1
-
37
-
-
71449123048
-
Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters
-
Picollo, A., Malvezzi, M., Houtman, J. & Accardi, A. Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters. Nat. Struct. Mol. Biol. 16, 1294-1301 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1294-1301
-
-
Picollo, A.1
Malvezzi, M.2
Houtman, J.3
Accardi, A.4
-
38
-
-
33748798473
-
Synergism between halide binding and proton transport in a CLC-type exchanger
-
Accardi, A., Lobet, S., Williams, C., Miller, C. & Dutzler, R. Synergism between halide binding and proton transport in a CLC-type exchanger. J. Mol. Biol. 362, 691-699 (2006).
-
(2006)
J. Mol. Biol.
, vol.362
, pp. 691-699
-
-
Accardi, A.1
Lobet, S.2
Williams, C.3
Miller, C.4
Dutzler, R.5
-
39
-
-
33947720910
-
+ exchange transporter
-
+ exchange transporter. J. Gen. Physiol. 129, 317-329 (2007).
-
(2007)
J. Gen. Physiol.
, vol.129
, pp. 317-329
-
-
Walden, M.1
-
40
-
-
0037126294
-
A biological role for prokaryotic ClC chloride channels
-
Iyer, R., Iverson, T.M., Accardi, A. & Miller, C. A biological role for prokaryotic ClC chloride channels. Nature 419, 715-718 (2002).
-
(2002)
Nature
, vol.419
, pp. 715-718
-
-
Iyer, R.1
Iverson, T.M.2
Accardi, A.3
Miller, C.4
-
42
-
-
33748310543
-
+ exchange transporter by polyatomic anions
-
+ exchange transporter by polyatomic anions. J. Mol. Biol. 362, 682-690 (2006).
-
(2006)
J. Mol. Biol.
, vol.362
, pp. 682-690
-
-
Nguitragool, W.1
Miller, C.2
-
43
-
-
30444442312
-
Ion-binding properties of the ClC chloride selectivity filter
-
Lobet, S. & Dutzler, R. Ion-binding properties of the ClC chloride selectivity filter. EMBO J. 25, 24-33 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 24-33
-
-
Lobet, S.1
Dutzler, R.2
-
45
-
-
59649097040
-
+ antiporter by a single point mutation
-
+ antiporter by a single point mutation. EMBO J. 28, 175-182 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 175-182
-
-
Zifarelli, G.1
Pusch, M.2
-
46
-
-
0025270712
-
Steady-state coupling of ion-channel conformations to a transmembrane ion gradient
-
Richard, E.A. & Miller, C. Steady-state coupling of ion-channel conformations to a transmembrane ion gradient. Science 247, 1208-1210 (1990).
-
(1990)
Science
, vol.247
, pp. 1208-1210
-
-
Richard, E.A.1
Miller, C.2
-
48
-
-
0042377364
-
Side-chain charge effects and conductance determinants in the pore of ClC-0 chloride channels
-
Chen, M.F. & Chen, T.Y. Side-chain charge effects and conductance determinants in the pore of ClC-0 chloride channels. J. Gen. Physiol. 122, 133-145 (2003).
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 133-145
-
-
Chen, M.F.1
Chen, T.Y.2
-
51
-
-
0031670461
-
Enthalpy and heat capacity changes for the proton dissociation of various buffer components in 0.1 M potassium chloride
-
Fukada, H. & Takahashi, K. Enthalpy and heat capacity changes for the proton dissociation of various buffer components in 0.1 M potassium chloride. Proteins 33, 159-166 (1998).
-
(1998)
Proteins
, vol.33
, pp. 159-166
-
-
Fukada, H.1
Takahashi, K.2
-
52
-
-
0032692857
-
High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel
-
Maduke, M., Pheasant, D.J. & Miller, C. High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel. J. Gen. Physiol. 114, 713-722 (1999).
-
(1999)
J. Gen. Physiol.
, vol.114
, pp. 713-722
-
-
Maduke, M.1
Pheasant, D.J.2
Miller, C.3
-
53
-
-
47149096704
-
CHARMM-GUI: A web-based graphical user interface for CHARMM
-
Jo, S., Kim, T., Iyer, V.G. & Im, W. CHARMM-GUI: a web-based graphical user interface for CHARMM. J. Comput. Chem. 29, 1859-1865 (2008).
-
(2008)
J. Comput. Chem.
, vol.29
, pp. 1859-1865
-
-
Jo, S.1
Kim, T.2
Iyer, V.G.3
Im, W.4
-
54
-
-
67650500988
-
CHARMM: The biomolecular simulation program
-
Brooks, B.R. et al. CHARMM: the biomolecular simulation program. J. Comput. Chem. 30, 1545-1614 (2009).
-
(2009)
J. Comput. Chem.
, vol.30
, pp. 1545-1614
-
-
Brooks, B.R.1
-
55
-
-
0041784950
-
All-atom empirical potential for molecular modeling and dynamics studies of proteins
-
MacKerell, A.D. Jr. et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. J. Phys. Chem. B 102, 3586-3616 (1998).
-
(1998)
J. Phys. Chem. B
, vol.102
, pp. 3586-3616
-
-
MacKerell Jr., A.D.1
-
56
-
-
78651250118
-
Absence of ion-binding affinity in the putatively inactivated low-[K+] structure of the KcsA potassium channel
-
Boiteux, C. & Bernèche, S. Absence of ion-binding affinity in the putatively inactivated low-[K+] structure of the KcsA potassium channel. Structure 19, 70-79 (2011).
-
(2011)
Structure
, vol.19
, pp. 70-79
-
-
Boiteux, C.1
Bernèche, S.2
-
57
-
-
0035277126
-
Extension to the weighted histogram analysis method: Combining umbrella sampling with free energy calculations
-
Souaille, M. & Roux, B. Extension to the weighted histogram analysis method: combining umbrella sampling with free energy calculations. Comput. Phys. Commun. 135, 40-57 (2001).
-
(2001)
Comput. Phys. Commun.
, vol.135
, pp. 40-57
-
-
Souaille, M.1
Roux, B.2
-
58
-
-
52949088587
-
Statistically optimal analysis of samples from multiple equilibrium states
-
Shirts, M.R. & Chodera, J.D. Statistically optimal analysis of samples from multiple equilibrium states. J. Chem. Phys. 129, 124105 (2008).
-
(2008)
J. Chem. Phys.
, vol.129
, pp. 124105
-
-
Shirts, M.R.1
Chodera, J.D.2
-
59
-
-
77955577540
-
Good practices in free-energy calculations
-
Pohorille, A., Jarzynski, C. & Chipot, C. Good practices in free-energy calculations. J. Phys. Chem. B 114, 10235-10253 (2010).
-
(2010)
J. Phys. Chem. B
, vol.114
, pp. 10235-10253
-
-
Pohorille, A.1
Jarzynski, C.2
Chipot, C.3
-
60
-
-
2542437774
-
Electrostatics of ion stabilization in a ClC chloride channel homolog from Escherichia coli
-
Faraldo-Gómez, J.D. & Roux, B. Electrostatics of ion stabilization in a ClC chloride channel homolog from Escherichia coli. J. Mol. Biol. 339, 981-1000 (2004).
-
(2004)
J. Mol. Biol.
, vol.339
, pp. 981-1000
-
-
Faraldo-Gómez, J.D.1
Roux, B.2
|