Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels

Nature

Volumn 427, Issue 6977, 2004, Pages 803-807

  Accardi, Alessio ^a   Miller, Christopher ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; MOLECULAR DYNAMICS; MUSCLE; NEGATIVE IONS; TRANSPORT PROPERTIES;

ANION CONDUCTANCE; PROKARYOTIC HOMOLOGUES;

CHLORINE COMPOUNDS;

ANTIPORTER; CHLORIDE; CHLORIDE CHANNEL; COTRANSPORTER; ESCHERICHIA COLI PROTEIN; PROTON;

BIOLOGY;

ACIDIFICATION; ACTIVE TRANSPORT; ANIMAL; ANION TRANSPORT; ARTICLE; BIOLOGICAL MODEL; CHANNEL GATING; CHEMICAL STRUCTURE; CHEMISTRY; CHLORIDE TRANSPORT; ELECTRIC CONDUCTIVITY; ENDOSOME; ESCHERICHIA COLI; EUKARYOTE; GENETICS; ION CONDUCTANCE; ION TRANSPORT; METABOLISM; MISSENSE MUTATION; PRIORITY JOURNAL; PROKARYOSIS; PROKARYOTE; PROTEIN CONFORMATION; PROTON TRANSPORT; SEQUENCE HOMOLOGY; SKELETAL MUSCLE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CHLORIDE CHANNELS; CHLORIDES; ELECTRIC CONDUCTIVITY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; ION TRANSPORT; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION, MISSENSE; PROKARYOTIC CELLS; PROTEIN CONFORMATION; PROTONS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; PROKARYOTA;

EID: 1542288949     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02314     Document Type: Article

References (35)

1. - channels. J. Gen. Physiol. 123, 109-119 (2004).
2. Iyer, R., Iverson, T. M., Accardi, A. & Miller, C. A biological role for prokaryotic ClC chloride channels. Nature 419, 715-718 (2002).
3. Maduke, M., Pheasant, D. J. & Miller, C. High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel. J. Gen. Physiol. 114, 713-722 (1999).
4. Foster, D. L., Garcia, M. L., Newmam, M. J., Patel, L. & Kaback, H. R. Lactose-proton symport by purified lac carrier protein. Biochemistry 21, 5634-5638 (1982).
5. 2+ exchange carrier from rat brain. Biochim. Biophys. Acta 690,133-144 (1982).
6. + exchanger. J. Membr. Biol. 101, 1-9 (1988).
7. Dutzler, R., Campbell, E. B., Cadene, M., Chait, B. T. & MacKinnon, R. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity. Nature 415, 287-294 (2002).
8. Dutzler, R., Campbell, E. B. & MacKinnon, R. Gating the selectivity filter in ClC chloride channels. Science 300, 108-112 (2003).
9. Miller, C. Open-state substructure of single chloride channels from Torpedo electroplax. Phil. Trans. R. Soc. B 299, 401-411 (1982).
10. Pusch, M., Steinmeyer, K. & Jentsch, T. J. Low single channel conductance of the major skeletal muscle chloride channel, ClC-1. Biophys. J. 66, 149-152 (1994).
11. Weinreich, F. & Jentsch, T. J. Pores formed by single subunits in mixed dimers of different CLC chloride channels. J. Biol. Chem. 276, 2347-2353 (2001).
12. + channel-Fab complex at 2.0 Å resolution. Nature 414, 43-48 (2001).
13. +)-ATPase characterized with a simple manual assay. Biochim. Biophys. Acta 904, 13-21 (1987).
14. Toyoshima, C. & Nomura, H. Structural changes in the calcium pump accompanying the dissociation of calcium. Mature 418, 605-611 (2002).
15. Hirai, T. et al. Three-dimensional structure of a bacterial oxalate transporter. Nature Struct. Biol. 9, 597-600 (2002).
16. Huang, Y., Lemieux, M. J., Song, J., Auer, M. & Wang, D. N. Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Science 301, 616-620 (2003).
17. Abramson, J. et al. Structure and mechanism of the lactose permease of Escherichia coli. Science 301, 610-615 (2003).
18. Lin, C. W. & Chen, T. Y. Probing the pore of ClC-0 by substituted cysteine accessibility method using methane thiosulfonate reagents. J. Gen. Physiol. 122, 147-159 (2003).
19. Chen, M. F. & Chen, T. Y. Side-chain charge effects and conductance determinants in the pore of ClC-0 chloride channels. J. Gen. Physiol. 122, 133-145 (2003).
20. Estevez, R., Schroeder, B. C., Accardi, A., Jentsch, T. J. & Pusch, M. Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron 38, 47-59 (2003).
21. Traverso, S., Elia, L. & Pusch, M. Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic inhibitor. J. Gen. Physiol. 122, 295-306 (2003).
22. Davidson, A. L. Mechanism of coupling of transport to hydrolysis in bacterial ATP-binding cassette transporters. J. Bacteriol. 184, 1225-1233 (2002).
23. - channel gating to an ATP hydrolysis cycle. Neuron 12, 473-482 (1994).
24. +-pump ligands modulate gating of palytoxin-induced ion channels. Proc. Natl Acad. Sci. USA 100, 501-505 (2003).
25. Mager, S. et al. Conducting states of a mammalian serotonin transporter. Neuron 12, 845-859 (1994).
26. Fairman, W. A., Vandenberg, R. J., Arriza, J. L., Kavanaugh, M. P. & Amara, S. G. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375, 599-603 (1995).
27. Adams, S. V. & DeFelice, L. J. Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis. Biophys. J. 85, 1548-1559 (2003).
28. Richard, E. A. & Miller, C. Steady-state coupling of ion-channel conformations to a transmembrane ion gradient. Science 247, 1208-1210 (1990).
29. - channel. J. Gen. Physiol. 108, 237-250 (1996).
30. Pusch, M., Ludewig, U., Rehfeldt, A. & Jentsch, T. J. Gating of the voltage-dependent chloride channel ClC-0 by the permeant anion. Nature 373, 527-531 (1995).
31. Biwersi, J., Tulk, B. & Verkman, A. S. Long-wavelength chloride-sensitive fluorescent indicators. Anal. Biochem. 219, 139-143 (1994),
32. Mitchell, P. & Moyle, J. Stoichiometry of proton translocation through the respiratory chain and adenosine triphosphatase systems of rat liver mitochondria. Nature 208, 147-151 (1965).
33. Hille, B. Ion Channels of Excitable Membranes (Sinauer, Sunderland, MA, 2001).
34. Robinson, R. A. & Stokes, R. H. Electrolyte Solutions (Butterworths, London, 1965).
35. Humphrey, W., Dalke, A. & Schulten, K. VMD: visual molecular dynamics. J. Mol. Graph, 14, 27-28, 33-38 (1996).