-
1
-
-
0032474692
-
Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial doppler ultrasonography
-
Adams RJ, Mc Kie VC, Hsu L et al (1998) Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial doppler ultrasonography. N Engl J Med 339(1):5-11
-
(1998)
N Engl J Med
, vol.339
, Issue.1
, pp. 5-11
-
-
Adams, R.J.1
Mc, V.C.2
Hsu, L.3
-
2
-
-
33747586761
-
Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia
-
Adewoye AH, Nolan VG, Ma Q et al (2006) Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia. Clin Infect Dis 43(5):593-598
-
(2006)
Clin Infect Dis
, vol.43
, Issue.5
, pp. 593-598
-
-
Adewoye, A.H.1
Nolan, V.G.2
Ma, Q.3
-
3
-
-
0036884534
-
Priapism in sickle-cell disease; incidence, risk factors and complications - An international multicentre study
-
Adeyoju AB, Olujohungbe AB, Morris J et al (2002) Priapism in sickle-cell disease; incidence, risk factors and complications - an international multicentre study. BJU Int 90(9):898-902
-
(2002)
BJU Int
, vol.90
, Issue.9
, pp. 898-902
-
-
Adeyoju, A.B.1
Olujohungbe, A.B.2
Morris, J.3
-
4
-
-
4143132048
-
Are there clinical phenotypes of homozygous sickle cell disease?
-
Alexander N, Higgs D, Dover G, Serjeant GR (2004) Are there clinical phenotypes of homozygous sickle cell disease? Br J Haematol 126(4):606-611
-
(2004)
Br J Haematol
, vol.126
, Issue.4
, pp. 606-611
-
-
Alexander, N.1
Higgs, D.2
Dover, G.3
Serjeant, G.R.4
-
5
-
-
84867458482
-
The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease
-
Al-Habboubi HH, Mahdi N, Abu-Hijleh TM et al (2012) The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease. Eur J Haematol 89(5):403-409
-
(2012)
Eur J Haematol
, vol.89
, Issue.5
, pp. 403-409
-
-
Al-Habboubi, H.H.1
Mahdi, N.2
Abu-Hijleh, T.M.3
-
6
-
-
42149175072
-
Evidence for HLA class II susceptible and protective haplotypes for osteomyelitis in pediatric patients with sickle cell anemia
-
Al-Ola K, Mahdi N, Al-Subaie AM et al (2008) Evidence for HLA class II susceptible and protective haplotypes for osteomyelitis in pediatric patients with sickle cell anemia. Tissue Antigens 71(5):453-457
-
(2008)
Tissue Antigens
, vol.71
, Issue.5
, pp. 453-457
-
-
Al-Ola, K.1
Mahdi, N.2
Al-Subaie, A.M.3
-
7
-
-
79952505965
-
The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease
-
Alves Jacob M, da Cunha Bastos C, Regina Bonini-Domingos C (2011) The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease. Arch Med Sci 7(1):97-101
-
(2011)
Arch Med Sci
, vol.7
, Issue.1
, pp. 97-101
-
-
Alves Jacob, M.1
Da Cunha Bastos, C.2
Regina Bonini-Domingos, C.3
-
8
-
-
0025781654
-
Monozygotic twins with sickle cell anemia and discordant clinical courses: Clinical and laboratory studies
-
Amin BR, Bauersachs RM, Meiselman HJ et al (1991) Monozygotic twins with sickle cell anemia and discordant clinical courses: clinical and laboratory studies. Hemoglobin 15(4): 247-256
-
(1991)
Hemoglobin
, vol.15
, Issue.4
, pp. 247-256
-
-
Amin, B.R.1
Bauersachs, R.M.2
Meiselman, H.J.3
-
9
-
-
0031825212
-
Prothrombin mutant, factor V Leiden, and thermolabile variant of methylenetetrahydrofolate reductase among patients with sickle cell disease in Brazil
-
Andrade FL, Annichino-Bizzacchi JM, Saad ST, Costa FF, Arruda VR (1998) Prothrombin mutant, factor V Leiden, and thermolabile variant of methylenetetrahydrofolate reductase among patients with sickle cell disease in Brazil. Am J Hematol 59(1):46-50
-
(1998)
Am J Hematol
, vol.59
, Issue.1
, pp. 46-50
-
-
Andrade, F.L.1
Annichino-Bizzacchi, J.M.2
Saad, S.T.3
Costa, F.F.4
Arruda, V.R.5
-
10
-
-
47049113837
-
Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease
-
Ashley-Koch AE, Elliott L, Kail ME et al (2008) Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease. Blood 111(12):5721-5726
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5721-5726
-
-
Ashley-Koch, A.E.1
Elliott, L.2
Kail, M.E.3
-
11
-
-
80053981734
-
MYH9 and APOL1 are both associated with sickle cell disease nephropathy
-
Ashley-Koch AE, Okocha EC, Garrett ME et al (2011) MYH9 and APOL1 are both associated with sickle cell disease nephropathy. Br J Haematol 155(3):386-394
-
(2011)
Br J Haematol
, vol.155
, Issue.3
, pp. 386-394
-
-
Ashley-Koch, A.E.1
Okocha, E.C.2
Garrett, M.E.3
-
12
-
-
84876206111
-
Outcome of cholelithiasis in Sudanese children with Sickle Cell Anaemia (SCA) after 13 years follow-up
-
Attalla BA, Karrar ZA, Ibnouf G et al (2013) Outcome of cholelithiasis in Sudanese children with Sickle Cell Anaemia (SCA) after 13 years follow-up. Afr Health Sci 13(1):154-159
-
(2013)
Afr Health Sci
, vol.13
, Issue.1
, pp. 154-159
-
-
Attalla, B.A.1
Karrar, Z.A.2
Ibnouf, G.3
-
13
-
-
80355125807
-
Variants in genetic modifiers of beta-thalassemia can help to predict the major or intermedia type of the disease
-
Badens C, Joly P, Agouti I et al (2011) Variants in genetic modifiers of beta-thalassemia can help to predict the major or intermedia type of the disease. Haematologica 96(11):1712-1714
-
(2011)
Haematologica
, vol.96
, Issue.11
, pp. 1712-1714
-
-
Badens, C.1
Joly, P.2
Agouti, I.3
-
14
-
-
84865714645
-
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans
-
Bae HT, Baldwin CT, Sebastiani P et al (2012) Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. Blood 120(9):1961-1962
-
(2012)
Blood
, vol.120
, Issue.9
, pp. 1961-1962
-
-
Bae, H.T.1
Baldwin, C.T.2
Sebastiani, P.3
-
15
-
-
22044456541
-
Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis
-
Baldwin C, Nolan VG, Wyszynski DF et al (2005) Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis. Blood 106(1):372-375
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 372-375
-
-
Baldwin, C.1
Nolan, V.G.2
Wyszynski, D.F.3
-
16
-
-
0035087188
-
Effect of alpha-globin genotype on the pathophysiology of sickle cell disease
-
Ballas SK (2001) Effect of alpha-globin genotype on the pathophysiology of sickle cell disease. Pediatr Pathol Mol Med 20(2):107-121
-
(2001)
Pediatr Pathol Mol Med
, vol.20
, Issue.2
, pp. 107-121
-
-
Ballas, S.K.1
-
17
-
-
45349085790
-
Current issues in sickle cell pain and its management
-
Ballas SK (2007) Current issues in sickle cell pain and its management. Hematology Am Soc Hematol Educ Program 97-105
-
(2007)
Hematology am Soc Hematol Educ Program
, pp. 97-105
-
-
Ballas, S.K.1
-
18
-
-
84864988793
-
Beyond the definitions of the phenotypic complications of sickle cell disease: An update on management
-
Ballas SK, Kesen MR, Goldberg MF et al (2012) Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management. ScientificWorldJournal 2012:949535
-
(2012)
Scientificworldjournal
, pp. 2012
-
-
Ballas, S.K.1
Kesen, M.R.2
Goldberg, M.F.3
-
19
-
-
80054746492
-
Exome sequencing as a tool for Mendelian disease gene discovery
-
Bamshad MJ, Ng SB, Bigham AW et al (2011) Exome sequencing as a tool for Mendelian disease gene discovery. Nat Rev Genet 12(11):745-755
-
(2011)
Nat Rev Genet
, vol.12
, Issue.11
, pp. 745-755
-
-
Bamshad, M.J.1
Ng, S.B.2
Bigham, A.W.3
-
20
-
-
84885620722
-
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
-
Bauer DE, Kamran SC, Lessard S et al (2013) An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science 342(6155):253-257
-
(2013)
Science
, vol.342
, Issue.6155
, pp. 253-257
-
-
Bauer, D.E.1
Kamran, S.C.2
Lessard, S.3
-
21
-
-
84868583137
-
Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease
-
Bean CJ, Boulet SL, Ellingsen D et al (2012) Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease. Blood 120(18):3822-3828
-
(2012)
Blood
, vol.120
, Issue.18
, pp. 3822-3828
-
-
Bean, C.J.1
Boulet, S.L.2
Ellingsen, D.3
-
22
-
-
77954423200
-
Prevalence and clinical correlates of microalbuminuria in children with sickle cell disease
-
Becton LJ, Kalpatthi RV, Rackoff E et al (2010) Prevalence and clinical correlates of microalbuminuria in children with sickle cell disease. Pediatr Nephrol 25(8):1505-1511
-
(2010)
Pediatr Nephrol
, vol.25
, Issue.8
, pp. 1505-1511
-
-
Becton, L.J.1
Kalpatthi, R.V.2
Rackoff, E.3
-
23
-
-
84926675673
-
Association of alpha-thalassemia, TNF-alpha (-308G>A) and VCAM-1 (c.1238G>C) gene polymorphisms with cerebrovascular disease in a newborn cohort of 411 children with sickle cell anemia
-
Belisario AR, Nogueira FL, Rodrigues RS et al (2015) Association of alpha-thalassemia, TNF-alpha (-308G>A) and VCAM-1 (c.1238G>C) gene polymorphisms with cerebrovascular disease in a newborn cohort of 411 children with sickle cell anemia. Blood Cells Mol Dis 54(1):44-50
-
(2015)
Blood Cells Mol Dis
, vol.54
, Issue.1
, pp. 44-50
-
-
Belisario, A.R.1
Nogueira, F.L.2
Rodrigues, R.S.3
-
24
-
-
58149143300
-
G6PD deficiency, absence of alpha-thalassemia, and hemolytic rate at baseline are significant independent risk factors for abnormally high cerebral velocities in patients with sickle cell anemia
-
Bernaudin F, Verlhac S, Chevret S et al (2008) G6PD deficiency, absence of alpha-thalassemia, and hemolytic rate at baseline are significant independent risk factors for abnormally high cerebral velocities in patients with sickle cell anemia. Blood 112(10):4314-4317
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4314-4317
-
-
Bernaudin, F.1
Verlhac, S.2
Chevret, S.3
-
25
-
-
79955518530
-
Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients
-
Bhatnagar P, Purvis S, Barron-Casella E et al (2011) Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients. J Hum Genet 56(4):316-323
-
(2011)
J Hum Genet
, vol.56
, Issue.4
, pp. 316-323
-
-
Bhatnagar, P.1
Purvis, S.2
Barron-Casella, E.3
-
26
-
-
78649452404
-
C-Myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression
-
Bianchi E, Zini R, Salati S et al (2010) c-Myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression. Blood 116(22):e99-e110
-
(2010)
Blood
, vol.116
, Issue.22
-
-
Bianchi, E.1
Zini, R.2
Salati, S.3
-
27
-
-
77956533115
-
Screening student athletes for sickle cell trait--a social and clinical experiment
-
Bonham VL, Dover GJ, Brody LC (2010) Screening student athletes for sickle cell trait--a social and clinical experiment. N Engl J Med 363(11):997-999
-
(2010)
N Engl J Med
, vol.363
, Issue.11
, pp. 997-999
-
-
Bonham, V.L.1
Dover, G.J.2
Brody, L.C.3
-
28
-
-
77956622584
-
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin
-
Borg J, Papadopoulos P, Georgitsi M et al (2010) Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet 42(9):801-805
-
(2010)
Nat Genet
, vol.42
, Issue.9
, pp. 801-805
-
-
Borg, J.1
Papadopoulos, P.2
Georgitsi, M.3
-
29
-
-
79955732301
-
Erythroid phenotypes associated with KLF1 mutations
-
Borg J, Patrinos GP, Felice AE, Philipsen S (2011) Erythroid phenotypes associated with KLF1 mutations. Haematologica 96(5):635-638
-
(2011)
Haematologica
, vol.96
, Issue.5
, pp. 635-638
-
-
Borg, J.1
Patrinos, G.P.2
Felice, A.E.3
Philipsen, S.4
-
30
-
-
0031878782
-
Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Congo
-
Bouanga JC, Mouele R, Prehu C et al (1998) Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Congo. Hum Hered 48(4):192-197
-
(1998)
Hum Hered
, vol.48
, Issue.4
, pp. 192-197
-
-
Bouanga, J.C.1
Mouele, R.2
Prehu, C.3
-
32
-
-
80053329221
-
TNF-alpha and IL-8: Serum levels and gene polymorphisms (-308G>A and -251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia
-
Cajado C, Cerqueira BA, Couto FD et al (2011) TNF-alpha and IL-8: serum levels and gene polymorphisms (-308G>A and -251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia. Cytokine 56(2):312-317
-
(2011)
Cytokine
, vol.56
, Issue.2
, pp. 312-317
-
-
Cajado, C.1
Cerqueira, B.A.2
Couto, F.D.3
-
33
-
-
0037186459
-
Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5)
-
Callahan JF, Burgess JL, Fornwald JA et al (2002) Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5). J Med Chem 45(5): 999-1001
-
(2002)
J Med Chem
, vol.45
, Issue.5
, pp. 999-1001
-
-
Callahan, J.F.1
Burgess, J.L.2
Fornwald, J.A.3
-
34
-
-
4644252441
-
Polymorphism of the human platelet antigen-5 system is a risk factor for occlusive vascular complications in patients with sickle cell anemia
-
Castro V, Alberto FL, Costa RN et al (2004) Polymorphism of the human platelet antigen-5 system is a risk factor for occlusive vascular complications in patients with sickle cell anemia. Vox Sang 87(2):118-123
-
(2004)
Vox Sang
, vol.87
, Issue.2
, pp. 118-123
-
-
Castro, V.1
Alberto, F.L.2
Costa, R.N.3
-
35
-
-
70349337710
-
HLA-G polymorphism influences the susceptibility to HCV infection in sickle cell disease patients
-
Cordero EA, Veit TD, da Silva MA et al (2009) HLA-G polymorphism influences the susceptibility to HCV infection in sickle cell disease patients. Tissue Antigens 74(4):308-313
-
(2009)
Tissue Antigens
, vol.74
, Issue.4
, pp. 308-313
-
-
Cordero, E.A.1
Veit, T.D.2
Da Silva, M.A.3
-
36
-
-
22544481795
-
Association of the G-463A myeloperoxidase polymorphism with infection in sickle cell anemia
-
Costa RN, Conran N, Albuquerque DM et al (2005) Association of the G-463A myeloperoxidase polymorphism with infection in sickle cell anemia. Haematologica 90(7):977-979
-
(2005)
Haematologica
, vol.90
, Issue.7
, pp. 977-979
-
-
Costa, R.N.1
Conran, N.2
Albuquerque, D.M.3
-
37
-
-
84900469368
-
Haptoglobin, alpha-thalassaemia and glucose-6-phosphate dehydrogenase polymorphisms and risk of abnormal transcranial Doppler among patients with sickle cell anaemia in Tanzania
-
Cox SE, Makani J, Soka D et al (2014) Haptoglobin, alpha-thalassaemia and glucose-6-phosphate dehydrogenase polymorphisms and risk of abnormal transcranial Doppler among patients with sickle cell anaemia in Tanzania. Br J Haematol 165(5):699-706
-
(2014)
Br J Haematol
, vol.165
, Issue.5
, pp. 699-706
-
-
Cox, S.E.1
Makani, J.2
Soka, D.3
-
38
-
-
0030065604
-
Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach
-
Craig JE, Rochette J, Fisher CA et al (1996) Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach. Nat Genet 12(1):58-64
-
(1996)
Nat Genet
, vol.12
, Issue.1
, pp. 58-64
-
-
Craig, J.E.1
Rochette, J.2
Fisher, C.A.3
-
39
-
-
33845916950
-
Asymptomatic cholelithiasis in children with sickle cell disease: Early or delayed cholecystectomy?
-
Curro G, Meo A, Ippolito D, Pusiol A, Cucinotta E (2007) Asymptomatic cholelithiasis in children with sickle cell disease: early or delayed cholecystectomy? Ann Surg 245(1):126-129
-
(2007)
Ann Surg
, vol.245
, Issue.1
, pp. 126-129
-
-
Curro, G.1
Meo, A.2
Ippolito, D.3
Pusiol, A.4
Cucinotta, E.5
-
40
-
-
6944253454
-
Physical and cognitive-behavioral activities used in the home management of sickle pain: A daily diary study in children and adolescents
-
Dampier C, Ely E, Eggleston B, Brodecki D, O’Neal P (2004) Physical and cognitive-behavioral activities used in the home management of sickle pain: a daily diary study in children and adolescents. Pediatr Blood Cancer 43(6):674-678
-
(2004)
Pediatr Blood Cancer
, vol.43
, Issue.6
, pp. 674-678
-
-
Dampier, C.1
Ely, E.2
Eggleston, B.3
Brodecki, D.4
O’ Neal, P.5
-
41
-
-
84856503066
-
Association between hemolysis and albuminuria in adults with sickle cell anemia
-
Day TG, Drasar ER, Fulford T, Sharpe CC, Thein SL (2012) Association between hemolysis and albuminuria in adults with sickle cell anemia. Haematologica 97(2):201-205
-
(2012)
Haematologica
, vol.97
, Issue.2
, pp. 201-205
-
-
Day, T.G.1
Drasar, E.R.2
Fulford, T.3
Sharpe, C.C.4
Thein, S.L.5
-
42
-
-
0008435402
-
Coinheritance of Gilbert syndrome increases the risk for developing gallstones in patients with hereditary spherocytosis
-
del Giudice EM, Perrotta S, Nobili B et al (1999) Coinheritance of Gilbert syndrome increases the risk for developing gallstones in patients with hereditary spherocytosis. Blood 94(7): 2259-2262
-
(1999)
Blood
, vol.94
, Issue.7
, pp. 2259-2262
-
-
Del Giudice, E.M.1
Perrotta, S.2
Nobili, B.3
-
43
-
-
66949125341
-
Effects of RANTES and MBL2 gene polymorphisms in sickle cell disease clinical outcomes: Association of the g.In1.1T>C RANTES variant with protection against infections
-
Dossou-Yovo OP, Zaccaria I, Benkerrou M et al (2009) Effects of RANTES and MBL2 gene polymorphisms in sickle cell disease clinical outcomes: association of the g.In1.1T>C RANTES variant with protection against infections. Am J Hematol 84(6):378-380
-
(2009)
Am J Hematol
, vol.84
, Issue.6
, pp. 378-380
-
-
Dossou-Yovo, O.P.1
Zaccaria, I.2
Benkerrou, M.3
-
44
-
-
84880969948
-
The effect of Duffy antigen receptor for chemo-kines on severity in sickle cell disease
-
Drasar ER, Menzel S, Fulford T, Thein SL (2013) The effect of Duffy antigen receptor for chemo-kines on severity in sickle cell disease. Haematologica 98(8):e87-e89
-
(2013)
Haematologica
, vol.98
, Issue.8
, pp. e87-e89
-
-
Drasar, E.R.1
Menzel, S.2
Fulford, T.3
Thein, S.L.4
-
45
-
-
0037443399
-
Stroke risk in siblings with sickle cell anemia
-
Driscoll MC, Hurlet A, Styles L et al (2003) Stroke risk in siblings with sickle cell anemia. Blood 101(6):2401-2404
-
(2003)
Blood
, vol.101
, Issue.6
, pp. 2401-2404
-
-
Driscoll, M.C.1
Hurlet, A.2
Styles, L.3
-
46
-
-
0026643316
-
Clinical and haematological diversity of sickle cell disease in Saudi children
-
El-Hazmi MA (1992) Clinical and haematological diversity of sickle cell disease in Saudi children. J Trop Pediatr 38(3):106-112
-
(1992)
J Trop Pediatr
, vol.38
, Issue.3
, pp. 106-112
-
-
El-Hazmi, M.A.1
-
47
-
-
34047205100
-
Genetic polymorphisms associated with priapism in sickle cell disease
-
Elliott L, Ashley-Koch AE, De Castro L et al (2007) Genetic polymorphisms associated with priapism in sickle cell disease. Br J Haematol 137(3):262-267
-
(2007)
Br J Haematol
, vol.137
, Issue.3
, pp. 262-267
-
-
Elliott, L.1
Ashley-Koch, A.E.2
De Castro, L.3
-
48
-
-
0020081165
-
Concurrent sickle-cell anemia and alpha-thalassemia: Effect on severity of anemia
-
Embury SH, Dozy AM, Miller J et al (1982) Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia. N Engl J Med 306(5):270-274
-
(1982)
N Engl J Med
, vol.306
, Issue.5
, pp. 270-274
-
-
Embury, S.H.1
Dozy, A.M.2
Miller, J.3
-
50
-
-
84878383486
-
Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice
-
Esteghamat F, Gillemans N, Bilic I et al (2013) Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood 121(13):2553-2562
-
(2013)
Blood
, vol.121
, Issue.13
, pp. 2553-2562
-
-
Esteghamat, F.1
Gillemans, N.2
Bilic, I.3
-
51
-
-
79955977896
-
A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression
-
Farrell JJ, Sherva RM, Chen ZY et al (2011) A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood 117(18):4935-4945
-
(2011)
Blood
, vol.117
, Issue.18
, pp. 4935-4945
-
-
Farrell, J.J.1
Sherva, R.M.2
Chen, Z.Y.3
-
52
-
-
0043133530
-
UDP-glucuronosyltransferase 1 gene promoter polymorphism is associated with increased serum bilirubin levels and cholecystectomy in patients with sickle cell anemia
-
Fertrin KY, Melo MB, Assis AM, Saad ST, Costa FF (2003) UDP-glucuronosyltransferase 1 gene promoter polymorphism is associated with increased serum bilirubin levels and cholecystectomy in patients with sickle cell anemia. Clin Genet 64(2):160-162
-
(2003)
Clin Genet
, vol.64
, Issue.2
, pp. 160-162
-
-
Fertrin, K.Y.1
Melo, M.B.2
Assis, A.M.3
Saad, S.T.4
Costa, F.F.5
-
53
-
-
0029861312
-
Effect of alpha-thalassemia and beta-globin gene cluster haplotypes on the hematological and clinical features of sickle-cell anemia in Brazil
-
Figueiredo MS, Kerbauy J, Goncalves MS et al (1996) Effect of alpha-thalassemia and beta-globin gene cluster haplotypes on the hematological and clinical features of sickle-cell anemia in Brazil. Am J Hematol 53(2):72-76
-
(1996)
Am J Hematol
, vol.53
, Issue.2
, pp. 72-76
-
-
Figueiredo, M.S.1
Kerbauy, J.2
Goncalves, M.S.3
-
54
-
-
79959278268
-
Genetic predictors for stroke in children with sickle cell anemia
-
Flanagan JM, Frohlich DM, Howard TA et al (2011) Genetic predictors for stroke in children with sickle cell anemia. Blood 117(24):6681-6684
-
(2011)
Blood
, vol.117
, Issue.24
, pp. 6681-6684
-
-
Flanagan, J.M.1
Frohlich, D.M.2
Howard, T.A.3
-
55
-
-
84879130688
-
Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia
-
Flanagan JM, Sheehan V, Linder H et al (2013) Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia. Blood 121(16):3237-3245
-
(2013)
Blood
, vol.121
, Issue.16
, pp. 3237-3245
-
-
Flanagan, J.M.1
Sheehan, V.2
Linder, H.3
-
56
-
-
0035676442
-
Cholelithiasis and Gilbert’s syndrome in homozygous beta-thalassaemia
-
Galanello R, Piras S, Barella S et al (2001) Cholelithiasis and Gilbert’s syndrome in homozygous beta-thalassaemia. Br J Haematol 115(4):926-928
-
(2001)
Br J Haematol
, vol.115
, Issue.4
, pp. 926-928
-
-
Galanello, R.1
Piras, S.2
Barella, S.3
-
57
-
-
70449719115
-
Amelioration of Sardinian beta-zero thalassemia by genetic modifiers
-
Galanello R, Sanna S, Perseu L et al (2009) Amelioration of Sardinian beta-zero thalassemia by genetic modifiers. Blood 114(18):3935-3937
-
(2009)
Blood
, vol.114
, Issue.18
, pp. 3935-3937
-
-
Galanello, R.1
Sanna, S.2
Perseu, L.3
-
58
-
-
78649469071
-
Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation
-
Galarneau G, Palmer CD, Sankaran VG et al (2010) Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation. Nat Genet 40(12):1049-1051
-
(2010)
Nat Genet
, vol.40
, Issue.12
, pp. 1049-1051
-
-
Galarneau, G.1
Palmer, C.D.2
Sankaran, V.G.3
-
59
-
-
84884621782
-
Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients
-
Galarneau G, Coady S, Garrett ME et al (2013) Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients. Blood 122(3):434-442
-
(2013)
Blood
, vol.122
, Issue.3
, pp. 434-442
-
-
Galarneau, G.1
Coady, S.2
Garrett, M.E.3
-
60
-
-
0033966370
-
Genetic influences on F cells and other hematologic variables: A twin heritability study
-
Garner C, Tatu T, Reittie JE et al (2000) Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood 95(1):342-346
-
(2000)
Blood
, vol.95
, Issue.1
, pp. 342-346
-
-
Garner, C.1
Tatu, T.2
Reittie, J.E.3
-
61
-
-
77955646179
-
Association of trypanolytic ApoL1 variants with kidney disease in African Americans
-
Genovese G, Friedman DJ, Ross MD et al (2010) Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science 329(5993):841-845
-
(2010)
Science
, vol.329
, Issue.5993
, pp. 841-845
-
-
Genovese, G.1
Friedman, D.J.2
Ross, M.D.3
-
62
-
-
10744233940
-
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
-
Gladwin MT, Sachdev V, Jison ML et al (2004) Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 350(9):886-895
-
(2004)
N Engl J Med
, vol.350
, Issue.9
, pp. 886-895
-
-
Gladwin, M.T.1
Sachdev, V.2
Jison, M.L.3
-
63
-
-
0004964584
-
The structure of human hemoglobin. VI. The sequence of amino acids in the tryptic peptides of the beta chain
-
Goldstein J, Konigsberg W, Hill RJ (1963) The structure of human hemoglobin. VI. The sequence of amino acids in the tryptic peptides of the beta chain. J Biol Chem 238:2016-2027
-
(1963)
J Biol Chem
, vol.238
, pp. 2016-2027
-
-
Goldstein, J.1
Konigsberg, W.2
Hill, R.J.3
-
64
-
-
84873589744
-
Candidate sequence variants and fetal hemoglobin in children with sickle cell disease treated with hydroxyurea
-
Green NS, Ender KL, Pashankar F et al (2013) Candidate sequence variants and fetal hemoglobin in children with sickle cell disease treated with hydroxyurea. PLoS One 8(2):e55709
-
(2013)
Plos One
, vol.8
, Issue.2
-
-
Green, N.S.1
Ender, K.L.2
Pashankar, F.3
-
65
-
-
0037388172
-
UGT1A promoter polymorphisms influence bilirubin response to hydroxyurea therapy in sickle cell anemia
-
Heeney MM, Howard TA, Zimmerman SA, Ware RE (2003) UGT1A promoter polymorphisms influence bilirubin response to hydroxyurea therapy in sickle cell anemia. J Lab Clin Med 141(4):279-282
-
(2003)
J Lab Clin Med
, vol.141
, Issue.4
, pp. 279-282
-
-
Heeney, M.M.1
Howard, T.A.2
Zimmerman, S.A.3
Ware, R.E.4
-
66
-
-
13144306071
-
Genome-wide association studies for common diseases and complex traits
-
Hirschhorn JN, Daly MJ (2005) Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 6(2):95-108
-
(2005)
Nat Rev Genet
, vol.6
, Issue.2
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
67
-
-
0038107362
-
Distinct HLA associations by stroke subtype in children with sickle cell anemia
-
Hoppe C, Klitz W, Noble J et al (2003) Distinct HLA associations by stroke subtype in children with sickle cell anemia. Blood 101(7):2865-2869
-
(2003)
Blood
, vol.101
, Issue.7
, pp. 2865-2869
-
-
Hoppe, C.1
Klitz, W.2
Noble, J.3
-
68
-
-
1542283710
-
Gene interactions and stroke risk in children with sickle cell anemia
-
Hoppe C, Klitz W, Cheng S et al (2004) Gene interactions and stroke risk in children with sickle cell anemia. Blood 103(6):2391-2396
-
(2004)
Blood
, vol.103
, Issue.6
, pp. 2391-2396
-
-
Hoppe, C.1
Klitz, W.2
Cheng, S.3
-
70
-
-
1842337282
-
Gene mutations in human haemoglobin: The chemical difference between normal and sickle cell haemoglobin
-
Ingram VM (1957) Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature 180(4581):326-328
-
(1957)
Nature
, vol.180
, Issue.4581
, pp. 326-328
-
-
Ingram, V.M.1
-
71
-
-
77955271206
-
Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus
-
Jawaid K, Wahlberg K, Thein SL, Best S (2010) Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus. Blood Cells Mol Dis 45(2):140-146
-
(2010)
Blood Cells Mol Dis
, vol.45
, Issue.2
, pp. 140-146
-
-
Jawaid, K.1
Wahlberg, K.2
Thein, S.L.3
Best, S.4
-
72
-
-
33746632097
-
CMYB is involved in the regulation of fetal hemoglobin production in adults
-
Jiang J, Best S, Menzel S et al (2006) cMYB is involved in the regulation of fetal hemoglobin production in adults. Blood 108(3):1077-1083
-
(2006)
Blood
, vol.108
, Issue.3
, pp. 1077-1083
-
-
Jiang, J.1
Best, S.2
Menzel, S.3
-
73
-
-
0017253381
-
Sickle b-thalassemia: Identical twins differing in severity implicate nongenetic factors influencing course
-
Joishy SK, Griner PF, Rowley PT (1976) Sickle b-thalassemia: identical twins differing in severity implicate nongenetic factors influencing course. Am J Hematol 1(1):23-33
-
(1976)
Am J Hematol
, vol.1
, Issue.1
, pp. 23-33
-
-
Joishy, S.K.1
Griner, P.F.2
Rowley, P.T.3
-
74
-
-
0034944343
-
The methylene tetrahydrofolate reductase (C677T) mutation as a potential risk factor for avascular necrosis in sickle cell disease
-
Kutlar A, Kutlar F, Turker I, Tural C (2001) The methylene tetrahydrofolate reductase (C677T) mutation as a potential risk factor for avascular necrosis in sickle cell disease. Hemoglobin 25(2):213-217
-
(2001)
Hemoglobin
, vol.25
, Issue.2
, pp. 213-217
-
-
Kutlar, A.1
Kutlar, F.2
Turker, I.3
Tural, C.4
-
75
-
-
0346497365
-
Common haplotype dependency of high G gamma-globin gene expression and high Hb F levels in beta-thalassemia and sickle cell anemia patients
-
Labie D, Pagnier J, Lapoumeroulie C et al (1985) Common haplotype dependency of high G gamma-globin gene expression and high Hb F levels in beta-thalassemia and sickle cell anemia patients. Proc Natl Acad Sci U S A 82(7):2111-2114
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, Issue.7
, pp. 2111-2114
-
-
Labie, D.1
Pagnier, J.2
Lapoumeroulie, C.3
-
76
-
-
50149117726
-
DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
-
Lettre G, Sankaran VG, Bezerra MA et al (2008) DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Proc Natl Acad Sci U S A 105(33):11869-11874
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.33
, pp. 11869-11874
-
-
Lettre, G.1
Sankaran, V.G.2
Bezerra, M.A.3
-
77
-
-
0035163071
-
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
-
Machado RD, Pauciulo MW, Thomson JR et al (2001) BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet 68(1):92-102
-
(2001)
Am J Hum Genet
, vol.68
, Issue.1
, pp. 92-102
-
-
Machado, R.D.1
Pauciulo, M.W.2
Thomson, J.R.3
-
78
-
-
84927663453
-
KLF1 null neonates display hydrops fetalis and a deranged erythroid transcriptome
-
Magor GW, Tallack MR, Gillinder KR et al (2015) KLF1 null neonates display hydrops fetalis and a deranged erythroid transcriptome. Blood 125:2405-2417
-
(2015)
Blood
, vol.125
, pp. 2405-2417
-
-
Magor, G.W.1
Tallack, M.R.2
Gillinder, K.R.3
-
79
-
-
78649444537
-
Strong association between a new marker of hemolysis and glomerulopathy in sickle cell anemia
-
Maier-Redelsperger M, Levy P, Lionnet F et al (2010) Strong association between a new marker of hemolysis and glomerulopathy in sickle cell anemia. Blood Cells Mol Dis 45(4):289-292
-
(2010)
Blood Cells Mol Dis
, vol.45
, Issue.4
, pp. 289-292
-
-
Maier-Redelsperger, M.1
Levy, P.2
Lionnet, F.3
-
80
-
-
79251553442
-
Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia
-
Makani J, Menzel S, Nkya S et al (2011) Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia. Blood 117(4):1390-1392
-
(2011)
Blood
, vol.117
, Issue.4
, pp. 1390-1392
-
-
Makani, J.1
Menzel, S.2
Nkya, S.3
-
81
-
-
84880920122
-
Bringing genome-wide association findings into clinical use
-
Manolio TA (2013) Bringing genome-wide association findings into clinical use. Nat Rev Genet 14(8):549-558
-
(2013)
Nat Rev Genet
, vol.14
, Issue.8
, pp. 549-558
-
-
Manolio, T.A.1
-
82
-
-
77950300877
-
Association of variant alleles of MBL2 gene with vasoocclusive crisis in children with sickle cell anemia
-
Mendonga TF, Oliveira MC, Vasconcelos LR et al (2010) Association of variant alleles of MBL2 gene with vasoocclusive crisis in children with sickle cell anemia. Blood Cells Mol Dis 44(4): 224-228
-
(2010)
Blood Cells Mol Dis
, vol.44
, Issue.4
, pp. 224-228
-
-
Mendonga, T.F.1
Oliveira, M.C.2
Vasconcelos, L.R.3
-
83
-
-
34748864128
-
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15
-
Menzel S, Garner C, Gut I et al (2007a) A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15. Nat Genet 39(10):1197-1199
-
(2007)
Nat Genet
, vol.39
, Issue.10
, pp. 1197-1199
-
-
Menzel, S.1
Garner, C.2
Gut, I.3
-
84
-
-
36348999843
-
The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans
-
Menzel S, Jiang J, Silver N et al (2007b) The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans. Blood 110(10): 3624-3626
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3624-3626
-
-
Menzel, S.1
Jiang, J.2
Silver, N.3
-
85
-
-
84870857735
-
HbA2 levels in normal adults are influenced by two distinct genetic mechanisms
-
Menzel S, Garner C, Rooks H, Spector TD, Thein SL (2013) HbA2 levels in normal adults are influenced by two distinct genetic mechanisms. Br J Haematol 160(1):101-105
-
(2013)
Br J Haematol
, vol.160
, Issue.1
, pp. 101-105
-
-
Menzel, S.1
Garner, C.2
Rooks, H.3
Spector, T.D.4
Thein, S.L.5
-
86
-
-
84908256845
-
Global genetic architecture of an erythroid quantitative trait locus, HMIP-2
-
Menzel S, Rooks H, Zelenika D et al (2014) Global genetic architecture of an erythroid quantitative trait locus, HMIP-2. Ann Hum Genet 78:434-451
-
(2014)
Ann Hum Genet
, vol.78
, pp. 434-451
-
-
Menzel, S.1
Rooks, H.2
Zelenika, D.3
-
87
-
-
0027211845
-
A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the KrUppel family of nuclear proteins
-
Miller IJ, Bieker JJ (1993) A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the KrUppel family of nuclear proteins. Mol Cell Biol 13(5):2776-2786
-
(1993)
Mol Cell Biol
, vol.13
, Issue.5
, pp. 2776-2786
-
-
Miller, I.J.1
Bieker, J.J.2
-
88
-
-
0034642592
-
Prediction of adverse outcomes in children with sickle cell disease
-
Miller ST, Sleeper LA, Pegelow CH et al (2000) Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med 342(2):83-89
-
(2000)
N Engl J Med
, vol.342
, Issue.2
, pp. 83-89
-
-
Miller, S.T.1
Sleeper, L.A.2
Pegelow, C.H.3
-
89
-
-
84860458015
-
A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia
-
Milton JN, Sebastiani P, Solovieff N et al (2012) A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. PLoS One 7(4):e34741
-
(2012)
Plos One
, vol.7
, Issue.4
-
-
Milton, J.N.1
Sebastiani, P.2
Solovieff, N.3
-
90
-
-
84910681449
-
Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania
-
Mtatiro SN, Singh T, Rooks H et al (2014) Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania. PLoS One 9(11):e111464
-
(2014)
Plos One
, vol.9
, Issue.11
-
-
Mtatiro, S.N.1
Singh, T.2
Rooks, H.3
-
91
-
-
0022001839
-
Hematologically and genetically distinct forms of sickle cell anemia in Africa. The Senegal type and the Benin type
-
Nagel RL, Fabry ME, Pagnier J et al (1985) Hematologically and genetically distinct forms of sickle cell anemia in Africa. The Senegal type and the Benin type. N Engl J Med 312(14):880-884
-
(1985)
N Engl J Med
, vol.312
, Issue.14
, pp. 880-884
-
-
Nagel, R.L.1
Fabry, M.E.2
Pagnier, J.3
-
92
-
-
0023265737
-
The hematologic characteristics of sickle cell anemia bearing the Bantu haplotype: The relationship between Gg and Hb F level
-
Gg and Hb F level. Blood 69:1026-1030
-
(1987)
Blood
, vol.69
, pp. 1026-1030
-
-
Nagel, R.L.1
Rao, S.K.2
Dunda-Belkhodja, O.3
-
93
-
-
0025729733
-
The Senegal DNA haplotype is associated with the amelioration of anemia in African-American sickle cell anemia patients
-
Nagel RL, Erlingsson S, Fabry ME et al (1991) The Senegal DNA haplotype is associated with the amelioration of anemia in African-American sickle cell anemia patients. Blood 77: 1371-1375
-
(1991)
Blood
, vol.77
, pp. 1371-1375
-
-
Nagel, R.L.1
Erlingsson, S.2
Fabry, M.E.3
-
94
-
-
84923776133
-
Sickle cell disease: Renal manifestations and mechanisms
-
Nath KA, Hebbel RP (2015) Sickle cell disease: renal manifestations and mechanisms. Nat Rev Nephrol 11(3):161-171
-
(2015)
Nat Rev Nephrol
, vol.11
, Issue.3
, pp. 161-171
-
-
Nath, K.A.1
Hebbel, R.P.2
-
95
-
-
84920841482
-
-
NIH Expert Panel Report
-
National Institutes of Health: National Heart Lung and Blood Institute (2014) Evidence-based management of sickle cell disease NIH Expert Panel Report
-
(2014)
Evidence-Based Management of Sickle Cell Disease
-
-
-
96
-
-
77955282543
-
Alpha-thalassemia is associated with a decreased occurrence and a delayed age-at-onset of albuminuria in sickle cell anemia patients
-
Nebor D, Broquere C, Brudey K et al (2010a) Alpha-thalassemia is associated with a decreased occurrence and a delayed age-at-onset of albuminuria in sickle cell anemia patients. Blood Cells Mol Dis 45(2):154-158
-
(2010)
Blood Cells Mol Dis
, vol.45
, Issue.2
, pp. 154-158
-
-
Nebor, D.1
Broquere, C.2
Brudey, K.3
-
97
-
-
77953290928
-
Association between Duffy antigen receptor for chemokines expression and levels of inflammation markers in sickle cell anemia patients
-
Nebor D, Durpes MC, Mougenel D et al (2010b) Association between Duffy antigen receptor for chemokines expression and levels of inflammation markers in sickle cell anemia patients. Clin Immunol 136(1):116-122
-
(2010)
Clin Immunol
, vol.136
, Issue.1
, pp. 116-122
-
-
Nebor, D.1
Durpes, M.C.2
Mougenel, D.3
-
98
-
-
0032829849
-
Genetic polymorphism of the mannose-binding protein gene in children with sickle cell disease: Identification of three new variant alleles and relationship to infections
-
Neonato MG, Lu CY, Guilloud-Bataille M et al (1999) Genetic polymorphism of the mannose-binding protein gene in children with sickle cell disease: identification of three new variant alleles and relationship to infections. Eur J Hum Genet 7(6):679-686
-
(1999)
Eur J Hum Genet
, vol.7
, Issue.6
, pp. 679-686
-
-
Neonato, M.G.1
Lu, C.Y.2
Guilloud-Bataille, M.3
-
99
-
-
84890907794
-
Endothelial nitric oxide synthase gene polymorphism is associated with sickle cell disease patients in India
-
Nishank SS, Singh MP, Yadav R et al (2013) Endothelial nitric oxide synthase gene polymorphism is associated with sickle cell disease patients in India. J Hum Genet 58(12):775-779
-
(2013)
J Hum Genet
, vol.58
, Issue.12
, pp. 775-779
-
-
Nishank, S.S.1
Singh, M.P.2
Yadav, R.3
-
100
-
-
0021045875
-
Intracellular polymerization of sickle hemoglobin. Effects of cell heterogeneity
-
Noguchi CT, Torchia DA, Schechter AN (1983) Intracellular polymerization of sickle hemoglobin. Effects of cell heterogeneity. J Clin Invest 72(3):846-852
-
(1983)
J Clin Invest
, vol.72
, Issue.3
, pp. 846-852
-
-
Noguchi, C.T.1
Torchia, D.A.2
Schechter, A.N.3
-
101
-
-
0023859033
-
Levels of fetal hemoglobin necessary for treatment of sickle cell disease
-
Noguchi CT, Rodgers GP, Serjeant G, Schechter AN (1988) Levels of fetal hemoglobin necessary for treatment of sickle cell disease. N Engl J Med 318(2):96-99
-
(1988)
N Engl J Med
, vol.318
, Issue.2
, pp. 96-99
-
-
Noguchi, C.T.1
Rodgers, G.P.2
Serjeant, G.3
Schechter, A.N.4
-
102
-
-
19944430732
-
Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia
-
Nolan VG, Baldwin C, Ma Q et al (2005) Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol 128(2):266-272
-
(2005)
Br J Haematol
, vol.128
, Issue.2
, pp. 266-272
-
-
Nolan, V.G.1
Baldwin, C.2
Ma, Q.3
-
103
-
-
33646271370
-
Sickle cell leg ulcers: Associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway
-
Nolan VG, Adewoye A, Baldwin C et al (2006) Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol 133(5):570-578
-
(2006)
Br J Haematol
, vol.133
, Issue.5
, pp. 570-578
-
-
Nolan, V.G.1
Adewoye, A.2
Baldwin, C.3
-
104
-
-
0035206893
-
Nucleotide variation regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region
-
Ofori-Acquah SF, Lalloz MR, Layton DM (2001) Nucleotide variation regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region. Blood Cells Mol Dis 27(5):803-811
-
(2001)
Blood Cells Mol Dis
, vol.27
, Issue.5
, pp. 803-811
-
-
Ofori-Acquah, S.F.1
Lalloz, M.R.2
Layton, D.M.3
-
105
-
-
66049157967
-
Association of the MBL2 gene EXON1 polymorphism and vasoocclusive crisis in patients with sickle cell anemia
-
Oliveira MC, Mendonca TF, Vasconcelos LR et al (2009) Association of the MBL2 gene EXON1 polymorphism and vasoocclusive crisis in patients with sickle cell anemia. Acta Haematol 121(4):212-215
-
(2009)
Acta Haematol
, vol.121
, Issue.4
, pp. 212-215
-
-
Oliveira, M.C.1
Mendonca, T.F.2
Vasconcelos, L.R.3
-
106
-
-
0034760144
-
Influence of bilirubin uridine diphosphate-glucuronosyltransferase 1A promoter polymorphisms on serum bilirubin levels and cholelithiasis in children with sickle cell anemia
-
Passon RG, Howard TA, Zimmerman SA, Schultz WH, Ware RE (2001) Influence of bilirubin uridine diphosphate-glucuronosyltransferase 1A promoter polymorphisms on serum bilirubin levels and cholelithiasis in children with sickle cell anemia. J Pediatr Hematol Oncol 23(7):448-451
-
(2001)
J Pediatr Hematol Oncol
, vol.23
, Issue.7
, pp. 448-451
-
-
Passon, R.G.1
Howard, T.A.2
Zimmerman, S.A.3
Schultz, W.H.4
Ware, R.E.5
-
107
-
-
2342458084
-
Sickle cell anemia, a molecular disease
-
Pauling L, Itano HA et al (1949) Sickle cell anemia, a molecular disease. Science 109(2835):443
-
(1949)
Science
, vol.109
, Issue.2835
, pp. 443
-
-
Pauling, L.1
Itano, H.A.2
-
108
-
-
0025770390
-
Pain in sickle cell disease: Rates and risk factors
-
Platt OS, Thorington BD, Brambilla DJ et al (1991) Pain in sickle cell disease: rates and risk factors. N Engl J Med 325(1):11-16
-
(1991)
N Engl J Med
, vol.325
, Issue.1
, pp. 11-16
-
-
Platt, O.S.1
Thorington, B.D.2
Brambilla, D.J.3
-
109
-
-
0028291736
-
Mortality in sickle cell disease: Life expectancy and risk factors for early death
-
Platt OS, Brambilla DJ, Rosse WF et al (1994) Mortality in sickle cell disease: life expectancy and risk factors for early death. N Engl J Med 330(23):1639-1644
-
(1994)
N Engl J Med
, vol.330
, Issue.23
, pp. 1639-1644
-
-
Platt, O.S.1
Brambilla, D.J.2
Rosse, W.F.3
-
110
-
-
0025756644
-
Beta s-gene-cluster haplotypes in sickle cell anemia. Clinical and hematologic features
-
Powars DR (1991) Beta s-gene-cluster haplotypes in sickle cell anemia. Clinical and hematologic features. Hematol Oncol Clin North Am 5(3):475-493
-
(1991)
Hematol Oncol Clin North Am
, vol.5
, Issue.3
, pp. 475-493
-
-
Powars, D.R.1
-
111
-
-
0035897912
-
Genetic determinants of jaundice and gallstones in haemoglobin
-
Premawardhena A, Fisher CA, Fathiu F et al (2001) Genetic determinants of jaundice and gallstones in haemoglobin E beta thalassaemia. Lancet 357(9272):1945-1946
-
(2001)
E Beta Thalassaemia. Lancet
, vol.357
, Issue.9272
, pp. 1945-1946
-
-
Premawardhena, A.1
Fisher, C.A.2
Fathiu, F.3
-
112
-
-
70149123073
-
Glucose 6 phosphate dehydrogenase deficiency is not associated with cerebrovascular disease in children with sickle cell anemia
-
author reply 743-744
-
Rees DC, Lambert C, Cooper E et al (2009) Glucose 6 phosphate dehydrogenase deficiency is not associated with cerebrovascular disease in children with sickle cell anemia. Blood 114(3):742-743, author reply 743-744
-
(2009)
Blood
, vol.114
, Issue.3
, pp. 742-743
-
-
Rees, D.C.1
Lambert, C.2
Cooper, E.3
-
114
-
-
57849083996
-
Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A
-
Sankaran VG, Menne TF, Xu J et al (2008) Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science 322(5909):1839-1842
-
(2008)
Science
, vol.322
, Issue.5909
, pp. 1839-1842
-
-
Sankaran, V.G.1
Menne, T.F.2
Xu, J.3
-
115
-
-
77949846880
-
Advances in the understanding of haemoglobin switching
-
Sankaran VG, Xu J, Orkin SH (2010) Advances in the understanding of haemoglobin switching. Br J Haematol 149(2):181-194
-
(2010)
Br J Haematol
, vol.149
, Issue.2
, pp. 181-194
-
-
Sankaran, V.G.1
Xu, J.2
Orkin, S.H.3
-
116
-
-
79952169016
-
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13
-
Sankaran VG, Menne TF, Scepanovic D et al (2011) MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. Proc Natl Acad Sci U S A 108(4):1519-1524
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.4
, pp. 1519-1524
-
-
Sankaran, V.G.1
Menne, T.F.2
Scepanovic, D.3
-
117
-
-
84892885498
-
Rare complete loss of function provides insight into a pleiotropic genome-wide association study locus
-
Sankaran VG, Joshi M, Agrawal A et al (2013) Rare complete loss of function provides insight into a pleiotropic genome-wide association study locus. Blood 122(23):3845-3847
-
(2013)
Blood
, vol.122
, Issue.23
, pp. 3845-3847
-
-
Sankaran, V.G.1
Joshi, M.2
Agrawal, A.3
-
118
-
-
34948867270
-
A network model to predict the risk of death in sickle cell disease
-
Sebastiani P, Nolan VG, Baldwin CT et al (2007) A network model to predict the risk of death in sickle cell disease. Blood 110(7):2727-2735
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2727-2735
-
-
Sebastiani, P.1
Nolan, V.G.2
Baldwin, C.T.3
-
119
-
-
74049109698
-
Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study
-
Sebastiani P, Solovieff N, Hartley SW et al (2010) Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. Am J Hematol 85(1):29-35
-
(2010)
Am J Hematol
, vol.85
, Issue.1
, pp. 29-35
-
-
Sebastiani, P.1
Solovieff, N.2
Hartley, S.W.3
-
121
-
-
33846881560
-
Elderly survivors with homozygous sickle cell disease
-
Serjeant GR, Higgs DR, Hambleton IR (2007) Elderly survivors with homozygous sickle cell disease. N Engl J Med 356(6):642-643
-
(2007)
N Engl J Med
, vol.356
, Issue.6
, pp. 642-643
-
-
Serjeant, G.R.1
Higgs, D.R.2
Hambleton, I.R.3
-
122
-
-
1642458091
-
Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease
-
Sharan K, Surrey S, Ballas S et al (2004) Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease. Br J Haematol 124(2):240-243
-
(2004)
Br J Haematol
, vol.124
, Issue.2
, pp. 240-243
-
-
Sharan, K.1
Surrey, S.2
Ballas, S.3
-
123
-
-
84902598265
-
How I treat renal complications in sickle cell disease
-
Sharpe CC, Thein SL (2014) How I treat renal complications in sickle cell disease. Blood 123(24):3720-3726
-
(2014)
Blood
, vol.123
, Issue.24
, pp. 3720-3726
-
-
Sharpe, C.C.1
Thein, S.L.2
-
124
-
-
84908031073
-
Glutathione S-transferase gene polymorphisms (GSTM1, GSTT1, and GSTP1) in Egyptian pediatric patients with sickle cell disease
-
Shiba HF, El-Ghamrawy MK, Shaheen IA, Ali RA, Mousa SM (2014) Glutathione S-transferase gene polymorphisms (GSTM1, GSTT1, and GSTP1) in Egyptian pediatric patients with sickle cell disease. Pediatr Dev Pathol 17(4):265-270
-
(2014)
Pediatr Dev Pathol
, vol.17
, Issue.4
, pp. 265-270
-
-
Shiba, H.F.1
El-Ghamrawy, M.K.2
Shaheen, I.A.3
Ali, R.A.4
Mousa, S.M.5
-
125
-
-
80052153840
-
The multifunctional role of EKLF/KLF1 during erythropoiesis
-
Siatecka M, Bieker JJ (2011) The multifunctional role of EKLF/KLF1 during erythropoiesis. Blood 118(8):2044-2054
-
(2011)
Blood
, vol.118
, Issue.8
, pp. 2044-2054
-
-
Siatecka, M.1
Bieker, J.J.2
-
126
-
-
84967584839
-
Sickle cell disease: A phenotypic patchwork
-
Pace BS, 1st edn, Imperial College Press, London
-
Smith-Whitley K, Pace BS (2007) Sickle cell disease: a phenotypic patchwork. In: Pace BS (ed) Renaissance of sickle cell disease research in the genome era, 1st edn. Imperial College Press, London, pp 45-67
-
(2007)
Renaissance of Sickle Cell Disease Research in the Genome Era
, pp. 45-67
-
-
Smith-Whitley, K.1
Pace, B.S.2
-
127
-
-
70350644759
-
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
-
Soranzo N, Spector TD, Mangino M et al (2009) A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet 41(11):1182-1190
-
(2009)
Nat Genet
, vol.41
, Issue.11
, pp. 1182-1190
-
-
Soranzo, N.1
Spector, T.D.2
Mangino, M.3
-
128
-
-
84857051019
-
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development
-
Stadhouders R, Thongjuea S, Andrieu-Soler C et al (2012) Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. EMBO J 31(4): 986-999
-
(2012)
EMBO J
, vol.31
, Issue.4
, pp. 986-999
-
-
Stadhouders, R.1
Thongjuea, S.2
Rieu-Soler, C.3
-
129
-
-
84897568562
-
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers
-
Stadhouders R, Aktuna S, Thongjuea S et al (2014) HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. J Clin Invest 124(4):1699-1710
-
(2014)
J Clin Invest
, vol.124
, Issue.4
, pp. 1699-1710
-
-
Stadhouders, R.1
Aktuna, S.2
Thongjuea, S.3
-
130
-
-
13844318521
-
Control of globin gene expression during development and ery-throid differentiation
-
Stamatoyannopoulos G (2005) Control of globin gene expression during development and ery-throid differentiation. Exp Hematol 33(3):259-271
-
(2005)
Exp Hematol
, vol.33
, Issue.3
, pp. 259-271
-
-
Stamatoyannopoulos, G.1
-
131
-
-
65549111723
-
Genetic etiologies for phenotypic diversity in sickle cell anemia
-
Steinberg MH (2009) Genetic etiologies for phenotypic diversity in sickle cell anemia. ScientificWorldJournal 9:46-67
-
(2009)
Scientificworldjournal
, vol.9
, pp. 46-67
-
-
Steinberg, M.H.1
-
132
-
-
0022808364
-
Alpha-thalassemia in blacks: Genetic and clinical aspects and interactions with the sickle hemoglobin gene
-
Steinberg MH, Embury SH (1986) Alpha-thalassemia in blacks: genetic and clinical aspects and interactions with the sickle hemoglobin gene. Blood 68(5):985-990
-
(1986)
Blood
, vol.68
, Issue.5
, pp. 985-990
-
-
Steinberg, M.H.1
Embury, S.H.2
-
133
-
-
84864016792
-
Genetic modifiers of sickle cell disease
-
Steinberg MH, Sebastiani P (2012) Genetic modifiers of sickle cell disease. Am J Hematol 87(8):795-803
-
(2012)
Am J Hematol
, vol.87
, Issue.8
, pp. 795-803
-
-
Steinberg, M.H.1
Sebastiani, P.2
-
134
-
-
0023898154
-
Effects of glucose-6-phosphate dehydrogenase deficiency upon sickle cell anemia
-
Steinberg MH, West MS, Gallagher D, Mentzer W (1988) Effects of glucose-6-phosphate dehydrogenase deficiency upon sickle cell anemia. Blood 71(3):748-752
-
(1988)
Blood
, vol.71
, Issue.3
, pp. 748-752
-
-
Steinberg, M.H.1
West, M.S.2
Gallagher, D.3
Mentzer, W.4
-
135
-
-
0030893396
-
Fetal hemoglobin in sickle cell anemia: Determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea
-
Steinberg MH, Lu ZH, Barton FB et al (1997) Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea. Blood 89(3):1078-1088
-
(1997)
Blood
, vol.89
, Issue.3
, pp. 1078-1088
-
-
Steinberg, M.H.1
Lu, Z.H.2
Barton, F.B.3
-
136
-
-
0034210945
-
Evidence for HLA-related susceptibility for stroke in children with sickle cell disease
-
Styles LA, Hoppe C, Klitz W et al (2000) Evidence for HLA-related susceptibility for stroke in children with sickle cell disease. Blood 95(11):3562-3567
-
(2000)
Blood
, vol.95
, Issue.11
, pp. 3562-3567
-
-
Styles, L.A.1
Hoppe, C.2
Klitz, W.3
-
137
-
-
0037114210
-
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome
-
Sullivan KJ, Kissoon N, Duckworth LJ et al (2001) Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome. Am J Respir Crit Care Med 164(12):2186-2190
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.12
, pp. 2186-2190
-
-
Sullivan, K.J.1
Kissoon, N.2
Duckworth, L.J.3
-
138
-
-
84876336589
-
Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model
-
Suzuki M, Yamazaki H, Mukai HY et al (2013) Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model. Mol Cell Biol 33(8):1687-1695
-
(2013)
Mol Cell Biol
, vol.33
, Issue.8
, pp. 1687-1695
-
-
Suzuki, M.1
Yamazaki, H.2
Mukai, H.Y.3
-
139
-
-
84906956364
-
Fetal globin gene repressors as drug targets for molecular therapies to treat the beta-globinopathies
-
Suzuki M, Yamamoto M, Engel JD (2014) Fetal globin gene repressors as drug targets for molecular therapies to treat the beta-globinopathies. Mol Cell Biol 34(19):3560-3569
-
(2014)
Mol Cell Biol
, vol.34
, Issue.19
, pp. 3560-3569
-
-
Suzuki, M.1
Yamamoto, M.2
Engel, J.D.3
-
140
-
-
84876298874
-
Three fingers on the switch: Kruppel-like factor 1 regulation of gamma-globin to beta-globin gene switching
-
Tallack MR, Perkins AC (2013) Three fingers on the switch: Kruppel-like factor 1 regulation of gamma-globin to beta-globin gene switching. Curr Opin Hematol 20(3):193-200
-
(2013)
Curr Opin Hematol
, vol.20
, Issue.3
, pp. 193-200
-
-
Tallack, M.R.1
Perkins, A.C.2
-
141
-
-
0036129580
-
Infectious complications in sickle cell disease are influenced by HLA class II alleles
-
Tamouza R, Neonato MG, Busson M et al (2002) Infectious complications in sickle cell disease are influenced by HLA class II alleles. Hum Immunol 63(3):194-199
-
(2002)
Hum Immunol
, vol.63
, Issue.3
, pp. 194-199
-
-
Tamouza, R.1
Neonato, M.G.2
Busson, M.3
-
142
-
-
35348987704
-
HLA-E*0101 allele in homozygous state favors severe bacterial infections in sickle cell anemia
-
Tamouza R, Busson M, Fortier C et al (2007) HLA-E*0101 allele in homozygous state favors severe bacterial infections in sickle cell anemia. Hum Immunol 68(10):849-853
-
(2007)
Hum Immunol
, vol.68
, Issue.10
, pp. 849-853
-
-
Tamouza, R.1
Busson, M.2
Fortier, C.3
-
143
-
-
0034776219
-
Polymorphisms within the angiotensinogen gene (GT-repeat) and the risk of stroke in pediatric patients with sickle cell disease: A case-control study
-
Tang DC, Prauner R, Liu W et al (2001) Polymorphisms within the angiotensinogen gene (GT-repeat) and the risk of stroke in pediatric patients with sickle cell disease: a case-control study. Am J Hematol 68(3):164-169
-
(2001)
Am J Hematol
, vol.68
, Issue.3
, pp. 164-169
-
-
Tang, D.C.1
Prauner, R.2
Liu, W.3
-
144
-
-
84921361762
-
Endothelial nitric oxide synthase gene intron 4 VNTR polymorphism in sickle cell disease: Relation to vasculopathy and disease severity
-
Tantawy AA, Adly AA, Ismail EA, Aly SH (2015) Endothelial nitric oxide synthase gene intron 4 VNTR polymorphism in sickle cell disease: relation to vasculopathy and disease severity. Pediatr Blood Cancer 62(3):389-394
-
(2015)
Pediatr Blood Cancer
, vol.62
, Issue.3
, pp. 389-394
-
-
Tantawy, A.A.1
Adly, A.A.2
Ismail, E.A.3
Aly, S.H.4
-
145
-
-
0037114628
-
Variants in the VCAM1 gene and risk for symptomatic stroke in sickle cell disease
-
Taylor JG, Tang DC, Savage SA et al (2002) Variants in the VCAM1 gene and risk for symptomatic stroke in sickle cell disease. Blood 100(13):4303-4309
-
(2002)
Blood
, vol.100
, Issue.13
, pp. 4303-4309
-
-
Taylor, J.G.1
Tang, D.C.2
Savage, S.A.3
-
146
-
-
47749090563
-
Chronic hyper-hemolysis in sickle cell anemia: Association of vascular complications and mortality with less frequent vasoocclusive pain
-
Taylor JG, Nolan VG, Mendelsohn L et al (2008) Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain. PLoS One 3(5):e2095
-
(2008)
Plos One
, vol.3
, Issue.5
-
-
Taylor, J.G.1
Nolan, V.G.2
Mendelsohn, L.3
-
147
-
-
84867463377
-
Magnetic resonance angiography-defined intracranial vasculopathy is associated with silent cerebral infarcts and glucose-6-phosphate dehydrogenase mutation in children with sickle cell anaemia
-
Thangarajh M, Yang G, Fuchs D et al (2012) Magnetic resonance angiography-defined intracranial vasculopathy is associated with silent cerebral infarcts and glucose-6-phosphate dehydrogenase mutation in children with sickle cell anaemia. Br J Haematol 159(3):352-359
-
(2012)
Br J Haematol
, vol.159
, Issue.3
, pp. 352-359
-
-
Thangarajh, M.1
Yang, G.2
Fuchs, D.3
-
148
-
-
81055147553
-
Genetic modifiers of sickle cell disease
-
Thein SL (2011) Genetic modifiers of sickle cell disease. Hemoglobin 35(5-6):589-606
-
(2011)
Hemoglobin
, vol.35
, Issue.5-6
, pp. 589-606
-
-
Thein, S.L.1
-
149
-
-
0032406849
-
Genetics of Hb F/F cell variance in adults and heterocellular hereditary persistence of fetal hemoglobin
-
Thein SL, Craig JE (1998) Genetics of Hb F/F cell variance in adults and heterocellular hereditary persistence of fetal hemoglobin. Hemoglobin 22:401-414
-
(1998)
Hemoglobin
, vol.22
, pp. 401-414
-
-
Thein, S.L.1
Craig, J.E.2
-
150
-
-
65349107708
-
Discovering the genetics underlying foetal haemoglobin production in adults
-
Thein SL, Menzel S (2009) Discovering the genetics underlying foetal haemoglobin production in adults. Br J Haematol 145(4):455-467
-
(2009)
Br J Haematol
, vol.145
, Issue.4
, pp. 455-467
-
-
Thein, S.L.1
Menzel, S.2
-
151
-
-
34547450531
-
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults
-
Thein SL, Menzel S, Peng X et al (2007) Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults. Proc Natl Acad Sci U S A 104(27):11346-11351
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.27
, pp. 11346-11351
-
-
Thein, S.L.1
Menzel, S.2
Peng, X.3
-
152
-
-
77949807007
-
Control of fetal hemoglobin: New insights emerging from genomics and clinical implications
-
Thein SL, Menzel S, Lathrop M, Garner C (2009) Control of fetal hemoglobin: new insights emerging from genomics and clinical implications. Hum Mol Genet 18(R2):R216-R223
-
(2009)
Hum Mol Genet
, vol.18
, Issue.R2
, pp. R216-R223
-
-
Thein, S.L.1
Menzel, S.2
Lathrop, M.3
Garner, C.4
-
153
-
-
0030890407
-
Benign clinical course in homozygous sickle cell disease: A search for predictors
-
Thomas PW, Higgs DR, Serjeant GR (1997) Benign clinical course in homozygous sickle cell disease: a search for predictors. J Clin Epidemiol 50(2):121-126
-
(1997)
J Clin Epidemiol
, vol.50
, Issue.2
, pp. 121-126
-
-
Thomas, P.W.1
Higgs, D.R.2
Serjeant, G.R.3
-
154
-
-
40349092939
-
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia
-
Uda M, Galanello R, Sanna S et al (2008) Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proc Natl Acad Sci U S A 105(5):1620-1625
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.5
, pp. 1620-1625
-
-
Uda, M.1
Galanello, R.2
Sanna, S.3
-
155
-
-
67649392384
-
Association of sickle avascular necrosis with bone morphogenic protein 6
-
Ulug P, Vasavda N, Awogbade M et al (2009) Association of sickle avascular necrosis with bone morphogenic protein 6. Ann Hematol 88(8):803-805
-
(2009)
Ann Hematol
, vol.88
, Issue.8
, pp. 803-805
-
-
Ulug, P.1
Vasavda, N.2
Awogbade, M.3
-
156
-
-
84871464519
-
Seventy-five genetic loci influencing the human red blood cell
-
van der Harst P, Zhang W, Mateo Leach I et al (2012) Seventy-five genetic loci influencing the human red blood cell. Nature 492(7429):369-375
-
(2012)
Nature
, vol.492
, Issue.7429
, pp. 369-375
-
-
Van Der Harst, P.1
Zhang, W.2
Mateo Leach, I.3
-
157
-
-
34250846041
-
The linear effects of alpha-thalassaemia, the UGT1A1 and HMOX1 polymorphisms on cholelithiasis in sickle cell disease
-
Vasavda N, Menzel S, Kondaveeti S et al (2007) The linear effects of alpha-thalassaemia, the UGT1A1 and HMOX1 polymorphisms on cholelithiasis in sickle cell disease. Br J Haematol 138(2):263-270
-
(2007)
Br J Haematol
, vol.138
, Issue.2
, pp. 263-270
-
-
Vasavda, N.1
Menzel, S.2
Kondaveeti, S.3
-
158
-
-
54849433162
-
The presence of alpha-thalassaemia trait blunts the response to hydroxycarbamide in patients with sickle cell disease
-
Vasavda N, Badiger S, Rees D et al (2008) The presence of alpha-thalassaemia trait blunts the response to hydroxycarbamide in patients with sickle cell disease. Br J Haematol 143(4): 589-592
-
(2008)
Br J Haematol
, vol.143
, Issue.4
, pp. 589-592
-
-
Vasavda, N.1
Badiger, S.2
Rees, D.3
-
159
-
-
84923948302
-
Interleukin-1beta and interleukin-6 gene polymorphisms are associated with manifestations of sickle cell anemia
-
Vicari P, Adegoke SA, Mazzotti DR et al (2015) Interleukin-1beta and interleukin-6 gene polymorphisms are associated with manifestations of sickle cell anemia. Blood Cells Mol Dis 54(3): 244-249
-
(2015)
Blood Cells Mol Dis
, vol.54
, Issue.3
, pp. 244-249
-
-
Vicari, P.1
Adegoke, S.A.2
Mazzotti, D.R.3
-
160
-
-
84897515773
-
Mutations in Kruppel-like factor 1 cause transfusion-dependent hemolytic anemia and persistence of embryonic globin gene expression
-
Viprakasit V, Ekwattanakit S, Riolueang S et al (2014) Mutations in Kruppel-like factor 1 cause transfusion-dependent hemolytic anemia and persistence of embryonic globin gene expression. Blood 123:1586-1595
-
(2014)
Blood
, vol.123
, pp. 1586-1595
-
-
Viprakasit, V.1
Ekwattanakit, S.2
Riolueang, S.3
-
161
-
-
52249110610
-
MRI abnormalities of the brain in one-year-old children with sickle cell anemia
-
Wang WC, Pavlakis SG, Helton KJ et al (2008) MRI abnormalities of the brain in one-year-old children with sickle cell anemia. Pediatr Blood Cancer 51(5):643-646
-
(2008)
Pediatr Blood Cancer
, vol.51
, Issue.5
, pp. 643-646
-
-
Wang, W.C.1
Pavlakis, S.G.2
Helton, K.J.3
-
162
-
-
77955905049
-
How I use hydroxyurea to treat young patients with sickle cell anemia
-
Ware RE (2010) How I use hydroxyurea to treat young patients with sickle cell anemia. Blood 115(26):5300-5311
-
(2010)
Blood
, vol.115
, Issue.26
, pp. 5300-5311
-
-
Ware, R.E.1
-
163
-
-
0036096085
-
Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy
-
Ware RE, Eggleston B, Redding-Lallinger R et al (2002) Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy. Blood 99(1):10-14
-
(2002)
Blood
, vol.99
, Issue.1
, pp. 10-14
-
-
Ware, R.E.1
Eggleston, B.2
Redding-Lallinger, R.3
-
164
-
-
28944452708
-
Phenotype/genotype relationships in sickle cell disease: A pilot twin study
-
Weatherall MW, Higgs DR, Weiss H, Weatherall DJ, Serjeant GR (2005) Phenotype/genotype relationships in sickle cell disease: a pilot twin study. Clin Lab Haematol 27(6): 384-390
-
(2005)
Clin Lab Haematol
, vol.27
, Issue.6
, pp. 384-390
-
-
Weatherall, M.W.1
Higgs, D.R.2
Weiss, H.3
Weatherall, D.J.4
Serjeant, G.R.5
-
165
-
-
8644228649
-
Global regulation of erythroid gene expression by transcription factor GATA-1
-
Welch JJ, Watts JA, Vakoc CR et al (2004) Global regulation of erythroid gene expression by transcription factor GATA-1. Blood 104(10):3136-3147
-
(2004)
Blood
, vol.104
, Issue.10
, pp. 3136-3147
-
-
Welch, J.J.1
Watts, J.A.2
Vakoc, C.R.3
-
166
-
-
79954568538
-
Transcriptional regulation of fetal to adult hemoglobin switching: New therapeutic opportunities
-
Wilber A, Nienhuis AW, Persons DA (2011) Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities. Blood 117(15):3945-3953
-
(2011)
Blood
, vol.117
, Issue.15
, pp. 3945-3953
-
-
Wilber, A.1
Nienhuis, A.W.2
Persons, D.A.3
-
167
-
-
84899893333
-
Association of variants at BCL11A and HBS1L-MYB with hemoglobin F and hospitalization rates among sickle cell patients in Cameroon
-
Wonkam A, Ngo Bitoungui VJ, Vorster AA et al (2014) Association of variants at BCL11A and HBS1L-MYB with hemoglobin F and hospitalization rates among sickle cell patients in Cameroon. PLoS One 9(3):e92506
-
(2014)
Plos One
, vol.9
, Issue.3
-
-
Wonkam, A.1
Ngo Bitoungui, V.J.2
Vorster, A.A.3
-
168
-
-
77950930726
-
Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6
-
Xu J, Sankaran VG, Ni M et al (2010) Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6. Genes Dev 24(8):783-798
-
(2010)
Genes Dev
, vol.24
, Issue.8
, pp. 783-798
-
-
Xu, J.1
Sankaran, V.G.2
Ni, M.3
-
169
-
-
81555205756
-
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing
-
Xu J, Peng C, Sankaran VG et al (2011) Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Science 334(6058):993-996
-
(2011)
Science
, vol.334
, Issue.6058
, pp. 993-996
-
-
Xu, J.1
Peng, C.2
Sankaran, V.G.3
-
170
-
-
84876239967
-
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A
-
Xu J, Bauer DE, Kerenyi MA et al (2013) Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A. Proc Natl Acad Sci U S A 110(16):6518-6523
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.16
, pp. 6518-6523
-
-
Xu, J.1
Bauer, D.E.2
Kerenyi, M.A.3
-
171
-
-
84907016412
-
Management of sickle cell disease: Summary of the 2014 evidence-based report by expert panel members
-
Yawn BP, Buchanan GR, Afenyi-Annan AN et al (2014) Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members. JAMA 312(10):1033-1048
-
(2014)
JAMA
, vol.312
, Issue.10
, pp. 1033-1048
-
-
Yawn, B.P.1
Buchanan, G.R.2
Afenyi-Annan, A.N.3
-
172
-
-
84899473094
-
Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease
-
Zhang X, Zhang W, Ma SF et al (2014) Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease. Circulation 129(16):1650-1658
-
(2014)
Circulation
, vol.129
, Issue.16
, pp. 1650-1658
-
-
Zhang, X.1
Zhang, W.2
Ma, S.F.3
-
173
-
-
77956630402
-
KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching
-
Zhou D, Liu K, Sun CW, Pawlik KM, Townes TM (2010) KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching. Nat Genet 42(9):742-744
-
(2010)
Nat Genet
, vol.42
, Issue.9
, pp. 742-744
-
-
Zhou, D.1
Liu, K.2
Sun, C.W.3
Pawlik, K.M.4
Townes, T.M.5
-
174
-
-
0031724415
-
Inherited DNA mutations contributing to thrombotic complications in patients with sickle cell disease
-
Zimmerman SA, Ware RE (1998) Inherited DNA mutations contributing to thrombotic complications in patients with sickle cell disease. Am J Hematol 59(4):267-272
-
(1998)
Am J Hematol
, vol.59
, Issue.4
, pp. 267-272
-
-
Zimmerman, S.A.1
Ware, R.E.2
|