Effects of RANTES and MBL2 gene polymorphisms in sickle cell disease clinical outcomes: Association of the g.In1.1T>C RANTES variant with protection against infections

American Journal of Hematology

Volumn 84, Issue 6, 2009, Pages 378-380

  Dossou Yovo, Omer Placide ^a,b,c,d   Zaccaria, Isabelle ^d   Benkerrou, Malika ^a,d   Hauchecorne, Michelle ^a,c   Alberti, Corinne ^d   Rahimy, Mohamed Chérif ^b   Elion, Jacques ^a,c   Lapoumeroulie, Claudine ^a,c  

^a INSERM   (France)

^b UNIVERSITY OF ABOMEY CALAVI   (Benin)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; MANNOSE BINDING LECTIN 2; RANTES;

ADOLESCENT; ARTICLE; BACTERIAL INFECTION; CHILD; DNA POLYMORPHISM; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; MORPHOLOGICAL TRAIT; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN VARIANT; RECURRENT INFECTION; SCHOOL CHILD; SICKLE CELL ANEMIA;

ANEMIA, SICKLE CELL; BACTEREMIA; CHEMOKINE CCL5; CHILD, PRESCHOOL; COHORT STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; INFANT, NEWBORN; MANNOSE-BINDING LECTIN; POLYMORPHISM, GENETIC; PROGNOSIS;

EID: 66949125341     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21411     Document Type: Article

References (30)

1. Serjeant GR, Serjeant BE. Sickle Cell Disease, 3rd ed. Oxford: Oxford University Press; 2001.
2. Embury SH, Dozy AM, Miller J, et al. Concurrent sickle-cell anemia and alpha-thalassemia: Effect on severity of anemia. N Engl J Med 1982;306:270-274. (Pubitemid 12165028)
3. Labie D, Pagnier J, Lapoumeroulie C, et al. Common haplotype dependency of high G gamma-globin gene expression and high Hb F levels in beta-thalassemia and sickle cell anemia patients. Proc Natl Acad Sci USA 1985;82:2111-2114. (Pubitemid 15056478)
4. Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 1994;330:1639-1644. (Pubitemid 124005049)
5. Steinberg MH, Adewoye AH. Modifier genes and sickle cell anemia. Curr Opin Hematol 2006;13:131-136. (Pubitemid 43755850)
6. Carpenter SL, Lieff S, Howard TA, et al. UGT1A1 promoter polymorphisms and the development of hyperbilirubinemia and gallbladder disease in children with sickle cell anemia. Am J Hematol 2008;83:800-803.
7. Darbari DS, van Schaik RH, Capparelli EV, et al. UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease. Am J Hematol 2008;83:200-202. (Pubitemid 351303943)
8. Nolan VG, Ma Q, Cohen HT, et al. Estimated glomerular filtration rate in sickle cell anemia is associated with polymorphisms of bone morphogenetic protein receptor 1B. Am J Hematol 2007;82:179-184. (Pubitemid 46363782)
9. Neonato MG, Lu CY, Guilloud-Bataille M, et al. Genetic polymorphism of the mannose-binding protein gene in children with sickle cell disease: Identification of three new variant alleles and relationship to infections. Eur J Hum Genet 1999;7:679-686. (Pubitemid 29424059)
10. Summerfield JA, Ryder S, Sumiya M, et al. Mannose binding protein gene mutations associated with unusual and severe infections in adults. Lancet 1995;345:886-889.
11. Dossou-Yovo OP, Lapoumeroulie C, Hauchecorne M, et al. Variants of the mannose-binding lectin gene in the benin population: Heterozygosity for the p.G57E allele may confer a selective advantage. Hum Biol 2008;79:687-698.
12. Cavaillon JM, Adib-Conquy M, Fitting C, et al. Cytokine cascade insepsis. Scand J infect Dis 2003;35:535-544.
13. Al-Sharif FM, Makki RF, Ollier WE, et al. A new microsatellite marker within the promoter region of the MIP-1A gene. Immunogenetics 1999;49:740-741. (Pubitemid 29278469)
14. Liu H, Chao D, Nakayama EE, et al. Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression. Proc Natl Acad Sci USA 1999;96:4581-4585. (Pubitemid 29190379)
15. An P, Nelson GW, Wang L, et al. Modulating influence on HIV/AIDS by interacting RANTES gene variants. Proc Natl Acad Sci USA 2002;99:10002-10007.
16. Reiche EM, Bonametti AM, Voltarelli JC, et al. Genetic polymorphisms in the chemokine and chemokine receptors: Impact on clinical course and therapy of the human immunodefiency virus type 1 infection (HIV-1). Curr Med Chem 2007;14:1325-1334. (Pubitemid 46746363)
17. Appay V, Rowland-Jones SL. RANTES: A versatile and controversial chemokine. Trends Immunol 2001;22:83-87. (Pubitemid 32667526)
18. Cooke GS, Tosh K, Ramaley PA, et al. A polymorphism that reduces RANTES expression is associated with protection from death in HIV-seropositive Ugandans with advanced disease. J Infect Dis 2006;194:666-669. (Pubitemid 44297853)
19. Nakajima K, Tanaka Y, Nomiyama T, et al. RANTES promoter genotype is associated with diabetic nephropathy in type 2 diabetic subjects. Diabetes Care 2003;26:892-898. (Pubitemid 36929361)
20. Ng MW, Zhou G, Chong WP, et al. The association of RANTES polymorphism withsevere acute respiratory syndrome in Hong Kong and Beijing Chinese. BMC Infect Dis 2007;7:50. (Pubitemid 47018667)
21. Rahimy MC, Gangbo A, Ahouignan G, et al. Effect of a comprehensive clinical care program on disease course in severely ill children with sickle cell anemia in a sub-Saharan African setting. Blood 2003;102:834-838. (Pubitemid 36917772)
22. Fournier C, Benkerrou M, Vilmer E, et al. [Development of care activities for children with sickle cell disease at the Robert-Debre Hospital (Paris), between 1992 and 1996]. Arch Pediatr 2000;7:465-473.
23. Ezekowitz RA. Genetic heterogeneity of mannose-binding proteins: The Jekyll and Hyde of innate immunity? Am J Hum Genet 1998;62:6-9.
24. Adewoye AH, Nolan VG, Ma Q, et al. Association of polymorphisms of IGF1R and genes in the transforming growth factor-beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia. Clin Infect Dis 2006;43:593-598. (Pubitemid 44267118)
25. Schall TJ. Biology of the RANTES/SIS cytokine family. Cytokine 1991;3:165-183.
26. Gonzalez E, Dhanda R, Bamshad M, et al. Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: Impact on the epidemiology of the HIV-1 pandemic. Proc Natl Acad Sci USA. 2001;98:5199-5204.
27. Sarfo BY, Singh S, Lilliard JW, et al. The cerebral-malaria-associated expression of RANTES, CCR3 and CCR5 in post-mortem tissue samples. Ann Trop Med Parasitol 2004;98:297-303.
28. John CC, Opika-Opoka R, Byarugaba J, et al. Low levels of RANTES are associated with mortality in children with cerebral malaria. J Infect Dis 2006;194:837-845. (Pubitemid 44344133)
29. Rivera A, Jarolim P, Bugnara C. Modulation of Gardos channel activity by cytokines in sickle erythrocytes. Blood 2002;99:357-603. (Pubitemid 34533004)
30. Nickel RG, Casolaro V, Wahn U, et al. Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES. J Immunol 2000;164:1612-1616. (Pubitemid 30067281)