Mutations in Krüppel-like factor 1 cause transfusion-dependent hemolytic anemia and persistence of embryonic globin gene expression

Blood

Volumn 123, Issue 10, 2014, Pages 1586-1595

  Viprakasit, Vip ^a   Ekwattanakit, Supachai ^a,b   Riolueang, Suchada ^a   Chalaow, Nipon ^a   Fisher, Chris ^c   Lower, Karen ^d   Kanno, Hitoshi ^e   Tachavanich, Kalaya ^a   Bejrachandra, Sasithorn ^a   Saipin, Jariya ^a   Juntharaniyom, Monthana ^f   Sanpakit, Kleebsabai ^a   Tanphaichitr, Voravarn S ^a   Songdej, Duantida ^c   Babbs, Christian ^c   Gibbons, Richard J ^c   Philipsen, Sjaak ^g   Higgs, Douglas R ^c  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d FLINDERS UNIVERSITY   (Australia)

^e TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^f KHON KAEN HOSPITAL   (Thailand)

^g ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HEMOGLOBIN; HEMOGLOBIN F; HERMES ANTIGEN; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 1; PYRUVATE KINASE; RNA; TRANS ACTING FACTOR; UNCLASSIFIED DRUG; ERYTHROID KRUPPEL LIKE FACTOR; ERYTHROID KRUPPEL-LIKE FACTOR; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN BETA CHAIN;

ADULT; ARTICLE; BLOOD TRANSFUSION; CHILD; CLINICAL ARTICLE; DISEASE SEVERITY; ERYTHROCYTE; ERYTHROCYTE MEMBRANE; ERYTHROCYTE SHAPE; ERYTHROID CELL; FEMALE; GENE EXPRESSION; GENE MUTATION; GLOBIN GENE; GLOBIN SYNTHESIS; HEMOGLOBIN SYNTHESIS; HEMOLYTIC ANEMIA; HETEROZYGOTE; HUMAN; HUMAN CELL; INFANT; MALE; MICROCYTOSIS; MIDDLE AGED; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA ANALYSIS; SCHOOL CHILD; YOUNG ADULT; ADOLESCENT; AMINO ACID SEQUENCE; BLOOD; CHEMISTRY; GENE EXPRESSION REGULATION; GENE ORDER; GENETICS; MEAN CORPUSCULAR VOLUME; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DOMAIN; SEQUENCE ALIGNMENT;

ADOLESCENT; ADULT; ALPHA-GLOBINS; AMINO ACID SEQUENCE; ANEMIA, HEMOLYTIC; BETA-GLOBINS; BLOOD TRANSFUSION; CHILD; CHILD, PRESCHOOL; CONSERVED SEQUENCE; ERYTHROCYTE INDICES; ERYTHROCYTES; FEMALE; FETAL HEMOGLOBIN; GENE EXPRESSION REGULATION; GENE ORDER; HUMANS; INFANT; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; SEQUENCE ALIGNMENT; YOUNG ADULT;

EID: 84897515773     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-09-526087     Document Type: Article

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