Variants in genetic modifiers of β-Thalassemia can help to predict the major or intermedia type of the disease

Haematologica

Volumn 96, Issue 11, 2011, Pages 1712-1714

  Badens, Catherine ^a,b   Joly, Philippe ^b,c   Agouti, Imane ^a   Thuret, Isabelle ^a,b   Gonnet, Katia ^a   Fattoum, Synda ^a   Francina, Alain ^c   Simeoni, Marie Claude ^d   Loundou, Anderson ^d   Pissard, Serge ^e  

^a TIMONE HOSPITAL   (France)

^b HÔpital d'Enfants de la Timone AP HM   (France)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

^e HENRI MONDOR HOSPITAL   (France)

Author keywords

thalassemia; Genetic modifiers; Intermedia; Major

Indexed keywords

HYDROXYUREA;

ACCURACY; ADOLESCENT; ADULT; ALPHA THALASSEMIA; ARTICLE; BCL11A GENE; BETA THALASSEMIA; BLOOD TRANSFUSION; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; EXON; GENE; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HBSB1L GENE; HUMAN; MAJOR CLINICAL STUDY; ONCOGENE C MYB; PHENOTYPE; PREDICTION; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SPLENECTOMY; THALASSEMIA MAJOR;

ADOLESCENT; ADULT; BETA-THALASSEMIA; CARRIER PROTEINS; CHILD; COHORT STUDIES; FEMALE; FRANCE; HUMANS; MALE; MIDDLE AGED; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-MYB; REGISTRIES;

EID: 80355125807     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.046748     Document Type: Article

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