Cholelithiasis and Gilbert's syndrome in homozygous β-thalassaemia

British Journal of Haematology

Volumn 115, Issue 4, 2001, Pages 926-928

  Galanello, R ^a,b   Piras, S ^a   Barella, S ^a   Leoni, G B ^a   Cipollina, M D ^a   Perseu, L ^a   Cao, A ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b Osp Regionale per le Microcitemie   (Italy)

Author keywords

thalassaemia; Cholelithiasis; Gilbert's syndrome; Hyperbilirubinaemia; UGT1 A1

Indexed keywords

BILIRUBIN; GLUCURONOSYLTRANSFERASE;

ADOLESCENT; ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; CHILD; CHOLELITHIASIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; DNA SEQUENCE; FEMALE; GALLSTONE; GENOTYPE; GILBERT DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRIORITY JOURNAL; PROMOTER REGION; RISK FACTOR; SEQUENCE ANALYSIS; THALASSEMIA MAJOR;

ADOLESCENT; ADULT; BETA-THALASSEMIA; CHILD; CHOLELITHIASIS; FEMALE; GENOTYPE; GILBERT DISEASE; GLUCURONOSYLTRANSFERASE; HOMOZYGOTE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROMOTER REGIONS (GENETICS); RISK FACTORS; TATA BOX;

EID: 0035676442     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.03200.x     Document Type: Article

References (11)

1. Cholelithiasis in children with thalassemia major: An ultrasonographic study
2. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
3. Cholelithiasis in thalassemia major
4. Possible role of a defect in hepatic bilirubin glucuronidation in the initiation of cholesterol gallstones
5. Hyperbilirubinaemia in heterozygous β-thalassaemia is related to co-inherited Gilbert's syndrome
6. Co-inherited Gilbert's syndrome: A factor determining hyperbilirubinemia in homozygous β-thalassemia
7. High incidence of cholelithiasis in older patients with homozygous beta-thalassemia
8. The incidence of gallbladder stones and gallbladder function in beta-thalassemic children
9. Coinheritance of Gilbert's syndrome increases the risk for developing gallstones in patients with hereditary spherocytosis
10. The incidence of biliary calculosis in β-thalassemia syndrome
11. Monoconjugated bilirubin is a major component of hemolysis-induced gallstones in mice