Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathies

Molecular and Cellular Biology

Volumn 34, Issue 19, 2014, Pages 3560-3569

  Suzuki, Mikiko ^a   Yamamoto, Masayuki ^a,b   Engel, James Douglas ^c  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN GAMMA CHAIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR GATA 1; HEMOGLOBIN F; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

BETA GLOBINOPATHY; CHROMATIN; FETAL GLOBIN GENE; GENE EXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; GLOBIN GENE; HEMATOLOGIC DISEASE; HUMAN; MOLECULARLY TARGETED THERAPY; NONHUMAN; REPRESSOR GENE; SHORT SURVEY; SICKLE CELL ANEMIA; THALASSEMIA MAJOR; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; HEMOGLOBINOPATHY; METABOLISM; MUTATION; PATHOLOGY; REVIEW;

FETAL HEMOGLOBIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HEMOGLOBINOPATHIES; HUMANS; MOLECULAR TARGETED THERAPY; MUTATION; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84906956364     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00714-14     Document Type: Short Survey

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