Genetic determinants of jaundice and gallstones in haemoglobin E β thalassaemia

Lancet

Volumn 357, Issue 9272, 2001, Pages 1945-1946

  Premawardhena, A ^b   Fisher, C A ^b   Fathiu, F ^a   De Silva, S ^a   Perera, W ^a   Peto, T E A ^b   Olivieri, N F ^c   Weatherall, D J ^b  

^a GENERAL HOSPITAL   (Sri Lanka)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; HEMOGLOBIN E;

ARTICLE; BETA THALASSEMIA; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GALLSTONE FORMATION; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HUMAN; JAUNDICE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; SRI LANKA;

EID: 0035897912     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)05082-0     Document Type: Article

References (5)

1. Thalassemia in Sri Lanka: Implications for the future health burden of Asian populations
2. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
3. Molecular pathology of Crigler-Najjar type I and II and Gilbert's syndromes
4. Coinheritance of Gilbert syndrome increases the risk for developing gallstones in patients with hereditary spherocytosis
5. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?