Glucose 6 phosphate dehydrogenase deficiency is not associated with cerebrovascular disease in children with sickle cell anemia

Blood

Volumn 114, Issue 3, 2009, Pages 742-743

  Rees, David C ^a   Lambert, Christopher ^a   Cooper, Elaine ^a   Bartram, Jack ^a   Goss, David ^a   Deane, Colin ^a   Thein, Swee Lay ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

ALPHA THALASSEMIA; CEREBROVASCULAR DISEASE; DATA ANALYSIS; DISEASE ASSOCIATION; DOPPLER ECHOGRAPHY; GENOTYPE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMOLYSIS; HUMAN; LETTER; MAGNETIC RESONANCE ANGIOGRAPHY; PRIORITY JOURNAL; SICKLE CELL ANEMIA; CHILD; ECHOGRAPHY; FEMALE; GLYCOGEN STORAGE DISEASE TYPE 1; MALE; NOTE; RETROSPECTIVE STUDY;

ANEMIA, SICKLE CELL; CEREBROVASCULAR DISORDERS; CHILD; FEMALE; GLYCOGEN STORAGE DISEASE TYPE I; HUMANS; MALE; RETROSPECTIVE STUDIES; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 70149123073     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-04-216861     Document Type: Letter

References (7)

1. Ohene-Frempong K, Weiner SJ, Sleeper LA, et al. Cooperative study of sickle cell disease: cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91:288-294.
2. Reiter CD, Wang X, Tanus-Santos JE, et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med. 2002;8:1383-1389. (Pubitemid 36019423)
3. O'Driscoll S, Height SE, Dick MC, Rees DC. Serum lactate dehydrogenase activity as a biomarker in children with sickle cell disease. Br J Haematol. 2008; 140:206-209. (Pubitemid 350265040)
4. Bernaudin F, Verlhac S, Chevret S, et al. G6PD deficiency, absence of alphathalassaemia, and hemolytic rate at baseline are significant independent risk factors for abnormally high cerebral velocities in patients with sickle cell anemia. Blood. 2008;112:4314-4317.
5. Rees DC, Dick MC, Height SE, et al. A simple index using age, hemoglobin, and aspartate transaminase predicts increased intracerebral blood velocity as measured by transcranial Doppler scanning in children with sickle cell anemia. Pediatrics. 2008;121:e1628-e1632.
6. Stevens MC, Maude GH, Beckford M, et al. Alpha thalassemia and the hematology of homozygous sickle cell disease in childhood. Blood. 1986;67: 411-414. (Pubitemid 16164657)
7. Adams R, McKie V, Nichols F, et al. The use of transcranial ultrasonography to predict stroke in sickle cell disease. N Engl J Med. 1992;326:605-610.