TNF-alpha and IL-8: Serum levels and gene polymorphisms (-308G>A and -251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia

Cytokine

Volumn 56, Issue 2, 2011, Pages 312-317

  Cajado, C ^a   Cerqueira, B A V ^a   Couto, F D ^a   Moura Neto, J P ^a   Vilas Boas, W ^a   Dorea, M J ^a   Lyra, I M ^c   Barbosa, C G ^a   Reis, M G ^a   Goncalves, M S ^a,b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^c Fundação de Hematologia e Hemoterapia do Estado da Bahia HEMOBA Salvador   (Brazil)

Author keywords

Alpha2 Thalassemia; Beta S globin Gene haplotypes; IL 8; Sickle cell anemia; TNF alpha

Indexed keywords

BETA GLOBIN; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGE; ALLELE; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GENE; GENE DELETION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; HAPLOTYPE; HUMAN; HUMAN CELL; IL8 GENE; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTECTION; PROTEIN BLOOD LEVEL; SCHOOL CHILD; SICKLE CELL ANEMIA; SPLENOMEGALY; TNF ALPHA GENE;

ADOLESCENT; ADULT; ALLELES; ANEMIA, SICKLE CELL; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HAPLOTYPES; HUMANS; INTERLEUKIN-8; MEDICAL HISTORY TAKING; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053329221     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2011.07.002     Document Type: Article

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