-
1
-
-
34848847286
-
Derivatives of the multiple keten group
-
Collie, J.N. Derivatives of the multiple keten group. J. Chem. Soc. Trans. 1907, 91, 1806-1813.
-
(1907)
J. Chem. Soc. Trans.
, vol.91
, pp. 1806-1813
-
-
Collie, J.N.1
-
2
-
-
0034887171
-
Polyketide biosynthesis: A millennium review
-
Staunton, J.; Weissman, K.J. Polyketide biosynthesis: A millennium review. Nat. Prod. Rep. 2001, 18, 380-416.
-
(2001)
Nat. Prod. Rep.
, vol.18
, pp. 380-416
-
-
Staunton, J.1
Weissman, K.J.2
-
3
-
-
0024976525
-
Rapamycin for immunosuppression in organ allografting
-
Calne, R.Y.; Collier, D.S.; Lim, S.; Pollard, S.G.; Samaan, A.; White, D.J.; Thiru, S. Rapamycin for immunosuppression in organ allografting. Lancet 1989, 2, 227.
-
(1989)
Lancet
, vol.2
, pp. 227
-
-
Calne, R.Y.1
Collier, D.S.2
Lim, S.3
Pollard, S.G.4
Samaan, A.5
White, D.J.6
Thiru, S.7
-
4
-
-
0018939225
-
Mevinolin - A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme a reductase and a cholesterol-lowering agent
-
Alberts, A.W.; Chen, J.; Kuron, G.; Hunt, J.; Huff, J.; Hoffman, C.; Rothrock, J.; Lopez, M.; Joshua, H.; Harris, E.; et al. Mevinolin - A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme a reductase and a cholesterol-lowering agent. Proc. Natl. Acad. Sci. USA 1980, 77, 3957-3961.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 3957-3961
-
-
Alberts, A.W.1
Chen, J.2
Kuron, G.3
Hunt, J.4
Huff, J.5
Hoffman, C.6
Rothrock, J.7
Lopez, M.8
Joshua, H.9
Harris, E.10
-
5
-
-
0017193382
-
Actinorhodin is a chromosomally-determined antibiotic in Streptomyces coelicolor A3(2)
-
Wright, L.F.; Hopwood, D.A. Actinorhodin is a chromosomally-determined antibiotic in Streptomyces coelicolor A3(2). J. Gen. Microbiol. 1976, 96, 289-297.
-
(1976)
J. Gen. Microbiol.
, vol.96
, pp. 289-297
-
-
Wright, L.F.1
Hopwood, D.A.2
-
6
-
-
84878138385
-
Mitonuclear protein imbalance as a conserved longevity mechanism
-
Houtkooper, R.H.; Mouchiroud, L.; Ryu, D.; Moullan, N.; Katsyuba, E.; Knott, G.; Williams, R.W.; Auwerx, J. Mitonuclear protein imbalance as a conserved longevity mechanism. Nature 2013, 497, 451-457.
-
(2013)
Nature
, vol.497
, pp. 451-457
-
-
Houtkooper, R.H.1
Mouchiroud, L.2
Ryu, D.3
Moullan, N.4
Katsyuba, E.5
Knott, G.6
Williams, R.W.7
Auwerx, J.8
-
7
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 2012, 75, 311-335.
-
(2012)
J. Nat. Prod.
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
8
-
-
33748546592
-
Total syntheses of polyketide-derived bioactive natural products
-
Tatsuta, K.; Hosokawa, S. Total syntheses of polyketide-derived bioactive natural products. Chem. Rec. 2006, 6, 217-233.
-
(2006)
Chem. Rec.
, vol.6
, pp. 217-233
-
-
Tatsuta, K.1
Hosokawa, S.2
-
9
-
-
84970600565
-
Studies in relation to biosynthesis. I. Some possible routes to derivatives of orcinol and phloroglucinol
-
Birch, A.J.; Donovan, F.W. Studies in relation to biosynthesis. I. Some possible routes to derivatives of orcinol and phloroglucinol. Aust. J. Chem. 1953, 6, 360-368.
-
(1953)
Aust. J. Chem.
, vol.6
, pp. 360-368
-
-
Birch, A.J.1
Donovan, F.W.2
-
10
-
-
84891396350
-
Engineering the acyltransferase substrate specificity of assembly line polyketide synthases
-
Dunn, B.J.; Khosla, C. Engineering the acyltransferase substrate specificity of assembly line polyketide synthases. J. R. Soc. Interface R. Soc. 2013, 10, 20130297.
-
(2013)
J. R. Soc. Interface R. Soc.
, vol.10
-
-
Dunn, B.J.1
Khosla, C.2
-
11
-
-
84859637416
-
Novel applications of plant polyketide synthases
-
Abe, I. Novel applications of plant polyketide synthases. Curr. Opin. Chem. Biol. 2012, 16, 179-185.
-
(2012)
Curr. Opin. Chem. Biol.
, vol.16
, pp. 179-185
-
-
Abe, I.1
-
12
-
-
84898545355
-
Progress challenges and opportunities for the re-engineering of trans-at polyketide synthases
-
Till, M.; Race, P.R. Progress challenges and opportunities for the re-engineering of trans-at polyketide synthases. Biotechnol. Lett. 2014, 36, 877-888.
-
(2014)
Biotechnol. Lett.
, vol.36
, pp. 877-888
-
-
Till, M.1
Race, P.R.2
-
13
-
-
0037398774
-
Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms
-
Shen, B. Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms. Curr. Opin. Chem. Biol. 2003, 7, 285-295.
-
(2003)
Curr. Opin. Chem. Biol.
, vol.7
, pp. 285-295
-
-
Shen, B.1
-
14
-
-
34250790717
-
Polyketides, proteins and genes in fungi: Programmed nano-machines begin to reveal their secrets
-
Cox, R.J. Polyketides, proteins and genes in fungi: Programmed nano-machines begin to reveal their secrets. Org. Biomol. Chem. 2007, 5, 2010-2026.
-
(2007)
Org. Biomol. Chem.
, vol.5
, pp. 2010-2026
-
-
Cox, R.J.1
-
15
-
-
84878999846
-
Confluence of structural and chemical biology: Plant polyketide synthases as biocatalysts for a bio-based future
-
Stewart, C., Jr.; Vickery, C.R.; Burkart, M.D.; Noel, J.P. Confluence of structural and chemical biology: Plant polyketide synthases as biocatalysts for a bio-based future. Curr. Opin. Plant Biol. 2013, 16, 365-372.
-
(2013)
Curr. Opin. Plant Biol.
, vol.16
, pp. 365-372
-
-
Stewart, C.1
Vickery, C.R.2
Burkart, M.D.3
Noel, J.P.4
-
16
-
-
0033606986
-
A new pathway for polyketide synthesis in microorganisms
-
Funa, N.; Ohnishi, Y.; Fujii, I.; Shibuya, M.; Ebizuka, Y.; Horinouchi, S. A new pathway for polyketide synthesis in microorganisms. Nature 1999, 400, 897-899.
-
(1999)
Nature
, vol.400
, pp. 897-899
-
-
Funa, N.1
Ohnishi, Y.2
Fujii, I.3
Shibuya, M.4
Ebizuka, Y.5
Horinouchi, S.6
-
17
-
-
0032912472
-
Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2,4-diacetylphloroglucinol from Pseudomonas fluorescens Q2-87
-
Bangera, M.G.; Thomashow, L.S. Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2,4-diacetylphloroglucinol from Pseudomonas fluorescens Q2-87. J. Bacteriol. 1999, 181, 3155-3163.
-
(1999)
J. Bacteriol.
, vol.181
, pp. 3155-3163
-
-
Bangera, M.G.1
Thomashow, L.S.2
-
18
-
-
0035914455
-
A polyketide synthase in glycopeptide biosynthesis: The biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine
-
Pfeifer, V.; Nicholson, G.J.; Ries, J.; Recktenwald, J.; Schefer, A.B.; Shawky, R.M.; Schroder, J.; Wohlleben, W.; Pelzer, S. A polyketide synthase in glycopeptide biosynthesis: The biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine. J. Biol. Chem. 2001, 276, 38370-38377.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38370-38377
-
-
Pfeifer, V.1
Nicholson, G.J.2
Ries, J.3
Recktenwald, J.4
Schefer, A.B.5
Shawky, R.M.6
Schroder, J.7
Wohlleben, W.8
Pelzer, S.9
-
19
-
-
17444429231
-
Discovery of a novel superfamily of type III polyketide synthases in Aspergillus oryzae
-
Seshime, Y.; Juvvadi, P.R.; Fujii, I.; Kitamoto, K. Discovery of a novel superfamily of type III polyketide synthases in Aspergillus oryzae. Biochem. Biophys. Res. Commun. 2005, 331, 253-260.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.331
, pp. 253-260
-
-
Seshime, Y.1
Juvvadi, P.R.2
Fujii, I.3
Kitamoto, K.4
-
20
-
-
34347255733
-
Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa
-
Funa, N.; Awakawa, T.; Horinouchi, S. Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa. J. Biol. Chem. 2007, 282, 14476-14481.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14476-14481
-
-
Funa, N.1
Awakawa, T.2
Horinouchi, S.3
-
21
-
-
80052960391
-
Cloning and characterization of a type III polyketide synthase from Aspergillus niger
-
Li, J.; Luo, Y.; Lee, J.K.; Zhao, H. Cloning and characterization of a type III polyketide synthase from Aspergillus niger. Bioorg. Med. Chem. Lett. 2011, 21, 6085-6089.
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 6085-6089
-
-
Li, J.1
Luo, Y.2
Lee, J.K.3
Zhao, H.4
-
22
-
-
0021099645
-
Substrate specificity of chalcone synthase from petroselinum hortense
-
Schuz, R.; Heller, W.; Hahlbrock, K. Substrate specificity of chalcone synthase from petroselinum hortense. J. Biol. Chem. 1983, 258, 6730-6734.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 6730-6734
-
-
Schuz, R.1
Heller, W.2
Hahlbrock, K.3
-
23
-
-
0032805888
-
Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis
-
Ferrer, J.L.; Jez, J.M.; Bowman, M.E.; Dixon, R.A.; Noel, J.P. Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis. Nat. Struct. Biol. 1999, 6, 775-784.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 775-784
-
-
Ferrer, J.L.1
Jez, J.M.2
Bowman, M.E.3
Dixon, R.A.4
Noel, J.P.5
-
24
-
-
0037319699
-
The chalcone synthase superfamily of type III polyketide synthases
-
Austin, M.B.; Noel, J.P. The chalcone synthase superfamily of type III polyketide synthases. Nat. Prod. Rep. 2003, 20, 79-110.
-
(2003)
Nat. Prod. Rep.
, vol.20
, pp. 79-110
-
-
Austin, M.B.1
Noel, J.P.2
-
25
-
-
0034620559
-
Dissection of malonyl-coenzyme a decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase
-
Jez, J.M.; Ferrer, J.L.; Bowman, M.E.; Dixon, R.A.; Noel, J.P. Dissection of malonyl-coenzyme a decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry 2000, 39, 890-902.
-
(2000)
Biochemistry
, vol.39
, pp. 890-902
-
-
Jez, J.M.1
Ferrer, J.L.2
Bowman, M.E.3
Dixon, R.A.4
Noel, J.P.5
-
26
-
-
4644270018
-
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases
-
Austin, M.B.; Bowman, M.E.; Ferrer, J.L.; Schroder, J.; Noel, J.P. An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases. Chem. Biol. 2004, 11, 1179-1194.
-
(2004)
Chem. Biol.
, vol.11
, pp. 1179-1194
-
-
Austin, M.B.1
Bowman, M.E.2
Ferrer, J.L.3
Schroder, J.4
Noel, J.P.5
-
27
-
-
77953053139
-
Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases
-
Abe, I.; Morita, H. Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases. Nat. Prod. Rep. 2010, 27, 809-838.
-
(2010)
Nat. Prod. Rep.
, vol.27
, pp. 809-838
-
-
Abe, I.1
Morita, H.2
-
28
-
-
84946150258
-
Synthetic polyketide enzymology: Platform for biosynthesis of antimicrobial polyketides
-
Go, M.K.; Wongsantichon, J.; Cheung, V.W.N.; Chow, J.Y.; Robinson, R.C.; Yew, W.S. Synthetic polyketide enzymology: Platform for biosynthesis of antimicrobial polyketides. ACS Catal. 2015, 5, 4033-4042.
-
(2015)
ACS Catal.
, vol.5
, pp. 4033-4042
-
-
Go, M.K.1
Wongsantichon, J.2
Cheung, V.W.N.3
Chow, J.Y.4
Robinson, R.C.5
Yew, W.S.6
-
29
-
-
0028321623
-
Evidence that stilbene synthases have developed from chalcone synthases several times in the course of evolution
-
Tropf, S.; Lanz, T.; Rensing, S.A.; Schroder, J.; Schroder, G. Evidence that stilbene synthases have developed from chalcone synthases several times in the course of evolution. J. Mol. Evol. 1994, 38, 610-618.
-
(1994)
J. Mol. Evol.
, vol.38
, pp. 610-618
-
-
Tropf, S.1
Lanz, T.2
Rensing, S.A.3
Schroder, J.4
Schroder, G.5
-
30
-
-
0032748084
-
Cross-reaction of chalcone synthase and stilbene synthase overexpressed in Escherichia coli
-
Yamaguchi, T.; Kurosaki, F.; Suh, D.Y.; Sankawa, U.; Nishioka, M.; Akiyama, T.; Shibuya, M.; Ebizuka, Y. Cross-reaction of chalcone synthase and stilbene synthase overexpressed in Escherichia coli. FEBS Lett. 1999, 460, 457-461.
-
(1999)
FEBS Lett.
, vol.460
, pp. 457-461
-
-
Yamaguchi, T.1
Kurosaki, F.2
Suh, D.Y.3
Sankawa, U.4
Nishioka, M.5
Akiyama, T.6
Shibuya, M.7
Ebizuka, Y.8
-
31
-
-
24644435453
-
Crystal structure of stilbene synthase from Arachis hypogaea
-
Shomura, Y.; Torayama, I.; Suh, D.Y.; Xiang, T.; Kita, A.; Sankawa, U.; Miki, K. Crystal structure of stilbene synthase from Arachis hypogaea. Proteins 2005, 60, 803-806.
-
(2005)
Proteins
, vol.60
, pp. 803-806
-
-
Shomura, Y.1
Torayama, I.2
Suh, D.Y.3
Xiang, T.4
Kita, A.5
Sankawa, U.6
Miki, K.7
-
32
-
-
4644298885
-
Biogenetically modeled synthesis of β-resorcylic acids
-
Harris, T.M.; Carney, R.L. Biogenetically modeled synthesis of β-resorcylic acids. J. Am. Chem. Soc. 1966, 88, 2053-2054.
-
(1966)
J. Am. Chem. Soc.
, vol.88
, pp. 2053-2054
-
-
Harris, T.M.1
Carney, R.L.2
-
33
-
-
0029278107
-
Chalcone synthase-like genes active during corolla development are differentially expressed and encode enzymes with different catalytic properties in Gerbera hybrida (asteraceae)
-
Helariutta, Y.; Elomaa, P.; Kotilainen, M.; Griesbach, R.J.; Schroder, J.; Teeri, T.H. Chalcone synthase-like genes active during corolla development are differentially expressed and encode enzymes with different catalytic properties in Gerbera hybrida (asteraceae). Plant Mol. Biol. 1995, 28, 47-60.
-
(1995)
Plant Mol. Biol.
, vol.28
, pp. 47-60
-
-
Helariutta, Y.1
Elomaa, P.2
Kotilainen, M.3
Griesbach, R.J.4
Schroder, J.5
Teeri, T.H.6
-
34
-
-
0032569804
-
New pathway to polyketides in plants
-
Eckermann, S.; Schroder, G.; Schmidt, J.; Strack, D.; Edrada, R.A.; Helariutta, Y.; Elomaa, P.; Kotilainen, M.; Kilpelainen, I.; Proksch, P.; et al. New pathway to polyketides in plants. Nature 1998, 396, 387-390.
-
(1998)
Nature
, vol.396
, pp. 387-390
-
-
Eckermann, S.1
Schroder, G.2
Schmidt, J.3
Strack, D.4
Edrada, R.A.5
Helariutta, Y.6
Elomaa, P.7
Kotilainen, M.8
Kilpelainen, I.9
Proksch, P.10
-
35
-
-
0034526571
-
Structural control of polyketide formation in plant-specific polyketide synthases
-
Jez, J.M.; Austin, M.B.; Ferrer, J.L.; Bowman, M.E.; Schroder, J.; Noel, J.P. Structural control of polyketide formation in plant-specific polyketide synthases. Chem. Biol. 2000, 7, 919-930.
-
(2000)
Chem. Biol.
, vol.7
, pp. 919-930
-
-
Jez, J.M.1
Austin, M.B.2
Ferrer, J.L.3
Bowman, M.E.4
Schroder, J.5
Noel, J.P.6
-
36
-
-
1642299704
-
The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide
-
Abe, I.; Utsumi, Y.; Oguro, S.; Noguchi, H. The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide. FEBS Lett. 2004, 562, 171-176.
-
(2004)
FEBS Lett.
, vol.562
, pp. 171-176
-
-
Abe, I.1
Utsumi, Y.2
Oguro, S.3
Noguchi, H.4
-
37
-
-
32644440102
-
Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase
-
Abe, I.; Watanabe, T.; Lou, W.; Noguchi, H. Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase. FEBS J. 2006, 273, 208-218.
-
(2006)
FEBS J.
, vol.273
, pp. 208-218
-
-
Abe, I.1
Watanabe, T.2
Lou, W.3
Noguchi, H.4
-
38
-
-
34247239393
-
Structural insight into chain-length control and product specificity of pentaketide chromone synthase from Aloe arborescens
-
Morita, H.; Kondo, S.; Oguro, S.; Noguchi, H.; Sugio, S.; Abe, I.; Kohno, T. Structural insight into chain-length control and product specificity of pentaketide chromone synthase from Aloe arborescens. Chem. Biol. 2007, 14, 359-369.
-
(2007)
Chem. Biol.
, vol.14
, pp. 359-369
-
-
Morita, H.1
Kondo, S.2
Oguro, S.3
Noguchi, H.4
Sugio, S.5
Abe, I.6
Kohno, T.7
-
39
-
-
63049114865
-
Novel type III polyketide synthases from Aloe arborescens
-
Mizuuchi, Y.; Shi, S.-P.; Wanibuchi, K.; Kojima, A.; Morita, H.; Noguchi, H.; Abe, I. Novel type III polyketide synthases from Aloe arborescens. FEBS J. 2009, 276, 2391-2401.
-
(2009)
FEBS J.
, vol.276
, pp. 2391-2401
-
-
Mizuuchi, Y.1
Shi, S.-P.2
Wanibuchi, K.3
Kojima, A.4
Morita, H.5
Noguchi, H.6
Abe, I.7
-
40
-
-
24744454823
-
Engineered biosynthesis of plant polyketides: Chain length control in an octaketide-producing plant type III polyketide synthase
-
Abe, I.; Oguro, S.; Utsumi, Y.; Sano, Y.; Noguchi, H. Engineered biosynthesis of plant polyketides: Chain length control in an octaketide-producing plant type III polyketide synthase. J. Am. Chem. Soc. 2005, 127, 12709-12716.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 12709-12716
-
-
Abe, I.1
Oguro, S.2
Utsumi, Y.3
Sano, Y.4
Noguchi, H.5
-
41
-
-
0001544701
-
P-coumaroyltriacetic acid synthase, a new homologue of chalcone synthase, from Hydrangea macrophylla var. thunbergii
-
Akiyama, T.; Shibuya, M.; Liu, H.M.; Ebizuka, Y. P-coumaroyltriacetic acid synthase, a new homologue of chalcone synthase, from Hydrangea macrophylla var. thunbergii. Eur. J. Biochem. 1999, 263, 834-839.
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 834-839
-
-
Akiyama, T.1
Shibuya, M.2
Liu, H.M.3
Ebizuka, Y.4
-
42
-
-
0037308046
-
Stilbenecarboxylate biosynthesis: A new function in the family of chalcone synthase-related proteins
-
Eckermann, C.; Schroder, G.; Eckermann, S.; Strack, D.; Schmidt, J.; Schneider, B.; Schroder, J. Stilbenecarboxylate biosynthesis: A new function in the family of chalcone synthase-related proteins. Phytochemistry 2003, 62, 271-286.
-
(2003)
Phytochemistry
, vol.62
, pp. 271-286
-
-
Eckermann, C.1
Schroder, G.2
Eckermann, S.3
Strack, D.4
Schmidt, J.5
Schneider, B.6
Schroder, J.7
-
43
-
-
0028919709
-
The inducible 9,10-dihydrophenanthrene pathway: Characterization and expression of bibenzyl synthase and s-adenosylhomocysteine hydrolase
-
Preisig-Muller, R.; Gnau, P.; Kindl, H. The inducible 9,10-dihydrophenanthrene pathway: Characterization and expression of bibenzyl synthase and s-adenosylhomocysteine hydrolase. Arch. Biochem. Biophys. 1995, 317, 201-207.
-
(1995)
Arch. Biochem. Biophys.
, vol.317
, pp. 201-207
-
-
Preisig-Muller, R.1
Gnau, P.2
Kindl, H.3
-
44
-
-
0034845768
-
Benzalacetone synthase. A novel polyketide synthase that plays a crucial role in the biosynthesis of phenylbutanones in Rheum palmatum
-
Abe, I.; Takahashi, H.; Morita, H.; Noguchi, H. Benzalacetone synthase. A novel polyketide synthase that plays a crucial role in the biosynthesis of phenylbutanones in Rheum palmatum. Eur. J. Biochem. 2001, 268, 3354-3359.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 3354-3359
-
-
Abe, I.1
Takahashi, H.2
Morita, H.3
Noguchi, H.4
-
45
-
-
76249110808
-
A structure-based mechanism for benzalacetone synthase from Rheum palmatum
-
Morita, H.; Shimokawa, Y.; Tanio, M.; Kato, R.; Noguchi, H.; Sugio, S.; Kohno, T.; Abe, I. A structure-based mechanism for benzalacetone synthase from Rheum palmatum. Proc. Natl. Acad. Sci. USA 2010, 107, 669-673.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 669-673
-
-
Morita, H.1
Shimokawa, Y.2
Tanio, M.3
Kato, R.4
Noguchi, H.5
Sugio, S.6
Kohno, T.7
Abe, I.8
-
46
-
-
77955661054
-
Structure-based engineering of benzalacetone synthase
-
Shimokawa, Y.; Morita, H.; Abe, I. Structure-based engineering of benzalacetone synthase. Bioorg. Med. Chem. Lett. 2010, 20, 5099-5103.
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 5099-5103
-
-
Shimokawa, Y.1
Morita, H.2
Abe, I.3
-
47
-
-
84881170598
-
Protein preparation, crystallization and preliminary X-ray analysis of Polygonum cuspidatum bifunctional chalcone synthase/benzalacetone synthase
-
Lu, H.; Yang, M.; Liu, C.; Lu, P.; Cang, H.; Ma, L. Protein preparation, crystallization and preliminary X-ray analysis of Polygonum cuspidatum bifunctional chalcone synthase/benzalacetone synthase. Acta Crystallogr. Sec. F Struct. Biol. Cryst. Commun. 2013, 69, 871-875.
-
(2013)
Acta Crystallogr. Sec. F Struct. Biol. Cryst. Commun.
, vol.69
, pp. 871-875
-
-
Lu, H.1
Yang, M.2
Liu, C.3
Lu, P.4
Cang, H.5
Ma, L.6
-
48
-
-
66449118206
-
Curcuminoid biosynthesis by two type III polyketide synthases in the herb curcuma longa
-
Katsuyama, Y.; Kita, T.; Funa, N.; Horinouchi, S. Curcuminoid biosynthesis by two type III polyketide synthases in the herb curcuma longa. J. Biol. Chem. 2009, 284, 11160-11170.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11160-11170
-
-
Katsuyama, Y.1
Kita, T.2
Funa, N.3
Horinouchi, S.4
-
49
-
-
78650544821
-
Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from oryza sativa
-
Morita, H.; Wanibuchi, K.; Nii, H.; Kato, R.; Sugio, S.; Abe, I. Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from oryza sativa. Proc. Natl. Acad. Sci. USA 2010, 107, 19778-19783.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 19778-19783
-
-
Morita, H.1
Wanibuchi, K.2
Nii, H.3
Kato, R.4
Sugio, S.5
Abe, I.6
-
50
-
-
71049132718
-
Biosynthesis of biphenyls and benzophenones - Evolution of benzoic acid-specific type III polyketide synthases in plants
-
Beerhues, L.; Liu, B. Biosynthesis of biphenyls and benzophenones - evolution of benzoic acid-specific type III polyketide synthases in plants. Phytochemistry 2009, 70, 1719-1727.
-
(2009)
Phytochemistry
, vol.70
, pp. 1719-1727
-
-
Beerhues, L.1
Liu, B.2
-
51
-
-
0037742330
-
Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: Cdna cloning, functional expression, and site-directed mutagenesis of two polyketide synthases
-
Liu, B.; Falkenstein-Paul, H.; Schmidt, W.; Beerhues, L. Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: Cdna cloning, functional expression, and site-directed mutagenesis of two polyketide synthases. Plant J. 2003, 34, 847-855.
-
(2003)
Plant J.
, vol.34
, pp. 847-855
-
-
Liu, B.1
Falkenstein-Paul, H.2
Schmidt, W.3
Beerhues, L.4
-
52
-
-
84859158491
-
Benzophenone synthase from garcinia mangostana l. Pericarps
-
Nualkaew, N.; Morita, H.; Shimokawa, Y.; Kinjo, K.; Kushiro, T.; De-Eknamkul, W.; Ebizuka, Y.; Abe, I. Benzophenone synthase from garcinia mangostana l. Pericarps. Phytochemistry 2012, 77, 60-69.
-
(2012)
Phytochemistry
, vol.77
, pp. 60-69
-
-
Nualkaew, N.1
Morita, H.2
Shimokawa, Y.3
Kinjo, K.4
Kushiro, T.5
De-Eknamkul, W.6
Ebizuka, Y.7
Abe, I.8
-
53
-
-
0029960196
-
Benzophenone synthase from cultured cells of Centaurium erythraea
-
Beerhues, L. Benzophenone synthase from cultured cells of Centaurium erythraea. FEBS Lett. 1996, 383, 264-266.
-
(1996)
FEBS Lett.
, vol.383
, pp. 264-266
-
-
Beerhues, L.1
-
54
-
-
34247350408
-
Biphenyl synthase, a novel type III polyketide synthase
-
Liu, B.; Raeth, T.; Beuerle, T.; Beerhues, L. Biphenyl synthase, a novel type III polyketide synthase. Planta 2007, 225, 1495-1503.
-
(2007)
Planta
, vol.225
, pp. 1495-1503
-
-
Liu, B.1
Raeth, T.2
Beuerle, T.3
Beerhues, L.4
-
55
-
-
0028087040
-
Purification and properties of acridone synthase from cell suspension cultures of Ruta graveolens L.
-
Baumert, A.; Maier, W.; Groger, D.; Deutzmann, R. Purification and properties of acridone synthase from cell suspension cultures of Ruta graveolens L. Z. Naturforsch. C 1994, 49, 26-32.
-
(1994)
Z. Naturforsch. C
, vol.49
, pp. 26-32
-
-
Baumert, A.1
Maier, W.2
Groger, D.3
Deutzmann, R.4
-
56
-
-
0033773791
-
Specifities of functionally expressed chalcone and acridone synthases from Ruta graveolens
-
Springob, K.; Lukacin, R.; Ernwein, C.; Groning, I.; Matern, U. Specifities of functionally expressed chalcone and acridone synthases from Ruta graveolens. Eur. J. Biochem. 2000, 267, 6552-6559.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6552-6559
-
-
Springob, K.1
Lukacin, R.2
Ernwein, C.3
Groning, I.4
Matern, U.5
-
57
-
-
84874915198
-
Identification and characterization of a type III polyketide synthase involved in quinolone alkaloid biosynthesis from Aegle marmelos correa
-
Resmi, M.S.; Verma, P.; Gokhale, R.S.; Soniya, E.V. Identification and characterization of a type III polyketide synthase involved in quinolone alkaloid biosynthesis from Aegle marmelos correa. J. Biol. Chem. 2013, 288, 7271-7281.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 7271-7281
-
-
Resmi, M.S.1
Verma, P.2
Gokhale, R.S.3
Soniya, E.V.4
-
58
-
-
0035940995
-
Transformation of acridone synthase to chalcone synthase
-
Lukacin, R.; Schreiner, S.; Matern, U. Transformation of acridone synthase to chalcone synthase. FEBS Lett. 2001, 508, 413-417.
-
(2001)
FEBS Lett.
, vol.508
, pp. 413-417
-
-
Lukacin, R.1
Schreiner, S.2
Matern, U.3
-
59
-
-
84885111664
-
Cloning and structure-function analyses of quinolone- and acridone-producing novel type III polyketide synthases from Citrus microcarpa
-
Mori, T.; Shimokawa, Y.; Matsui, T.; Kinjo, K.; Kato, R.; Noguchi, H.; Sugio, S.; Morita, H.; Abe, I. Cloning and structure-function analyses of quinolone- and acridone-producing novel type III polyketide synthases from Citrus microcarpa. J. Biol. Chem. 2013, 288, 28845-28858.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 28845-28858
-
-
Mori, T.1
Shimokawa, Y.2
Matsui, T.3
Kinjo, K.4
Kato, R.5
Noguchi, H.6
Sugio, S.7
Morita, H.8
Abe, I.9
-
60
-
-
84884692338
-
Structure/function analysis of a type III polyketide synthase in the brown alga ectocarpus siliculosus reveals a biochemical pathway in phlorotannin monomer biosynthesis
-
Meslet-Cladiere, L.; Delage, L.; Leroux, C.J.; Goulitquer, S.; Leblanc, C.; Creis, E.; Gall, E.A.; Stiger-Pouvreau, V.; Czjzek, M.; Potin, P. Structure/function analysis of a type III polyketide synthase in the brown alga ectocarpus siliculosus reveals a biochemical pathway in phlorotannin monomer biosynthesis. Plant Cell 2013, 25, 3089-3103.
-
(2013)
Plant Cell
, vol.25
, pp. 3089-3103
-
-
Meslet-Cladiere, L.1
Delage, L.2
Leroux, C.J.3
Goulitquer, S.4
Leblanc, C.5
Creis, E.6
Gall, E.A.7
Stiger-Pouvreau, V.8
Czjzek, M.9
Potin, P.10
-
61
-
-
68549104290
-
Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases
-
Miyanaga, A.; Horinouchi, S. Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases. J. Antibiot. 2009, 62, 371-376.
-
(2009)
J. Antibiot.
, vol.62
, pp. 371-376
-
-
Miyanaga, A.1
Horinouchi, S.2
-
62
-
-
79551617015
-
LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana
-
Kim, S.S.; Grienenberger, E.; Lallemand, B.; Colpitts, C.C.; Kim, S.Y.; Souza Cde, A.; Geoffroy, P.; Heintz, D.; Krahn, D.; Kaiser, M.; et al. LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana. Plant Cell 2010, 22, 4045-4066.
-
(2010)
Plant Cell
, vol.22
, pp. 4045-4066
-
-
Kim, S.S.1
Grienenberger, E.2
Lallemand, B.3
Colpitts, C.C.4
Kim, S.Y.5
Souza Cde, A.6
Geoffroy, P.7
Heintz, D.8
Krahn, D.9
Kaiser, M.10
-
63
-
-
81055156965
-
Ppascl, a moss ortholog of anther-specific chalcone synthase-like enzymes, is a hydroxyalkylpyrone synthase involved in an evolutionarily conserved sporopollenin biosynthesis pathway
-
Colpitts, C.C.; Kim, S.S.; Posehn, S.E.; Jepson, C.; Kim, S.Y.; Wiedemann, G.; Reski, R.; Wee, A.G.; Douglas, C.J.; Suh, D.Y. Ppascl, a moss ortholog of anther-specific chalcone synthase-like enzymes, is a hydroxyalkylpyrone synthase involved in an evolutionarily conserved sporopollenin biosynthesis pathway. New Phytol. 2011, 192, 855-868.
-
(2011)
New Phytol.
, vol.192
, pp. 855-868
-
-
Colpitts, C.C.1
Kim, S.S.2
Posehn, S.E.3
Jepson, C.4
Kim, S.Y.5
Wiedemann, G.6
Reski, R.7
Wee, A.G.8
Douglas, C.J.9
Suh, D.Y.10
-
64
-
-
0037085447
-
Properties and substrate specificity of rppa, a chalcone synthase-related polyketide synthase in Streptomyces griseus
-
Funa, N.; Ohnishi, Y.; Ebizuka, Y.; Horinouchi, S. Properties and substrate specificity of rppa, a chalcone synthase-related polyketide synthase in Streptomyces griseus. J. Biol. Chem. 2002, 277, 4628-4635.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4628-4635
-
-
Funa, N.1
Ohnishi, Y.2
Ebizuka, Y.3
Horinouchi, S.4
-
65
-
-
0141483081
-
Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2)
-
Izumikawa, M.; Shipley, P.R.; Hopke, J.N.; O'Hare, T.; Xiang, L.; Noel, J.P.; Moore, B.S. Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2). J. Ind. Microbiol. Biotechnol. 2003, 30, 510-515.
-
(2003)
J. Ind. Microbiol. Biotechnol.
, vol.30
, pp. 510-515
-
-
Izumikawa, M.1
Shipley, P.R.2
Hopke, J.N.3
O'Hare, T.4
Xiang, L.5
Noel, J.P.6
Moore, B.S.7
-
66
-
-
7244239181
-
Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates
-
Austin, M.B.; Izumikawa, M.; Bowman, M.E.; Udwary, D.W.; Ferrer, J.L.; Moore, B.S.; Noel, J.P. Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates. J. Biol. Chem. 2004, 279, 45162-45174.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45162-45174
-
-
Austin, M.B.1
Izumikawa, M.2
Bowman, M.E.3
Udwary, D.W.4
Ferrer, J.L.5
Moore, B.S.6
Noel, J.P.7
-
67
-
-
17644390561
-
Biosynthesis of phloroglucinol
-
Achkar, J.; Xian, M.; Zhao, H.; Frost, J.W. Biosynthesis of phloroglucinol. J. Am. Chem. Soc. 2005, 127, 5332-5333.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 5332-5333
-
-
Achkar, J.1
Xian, M.2
Zhao, H.3
Frost, J.W.4
-
68
-
-
33845968510
-
Characterization of the substrate specificity of phld, a type III polyketide synthase from Pseudomonas fluorescens
-
Zha, W.; Rubin-Pitel, S.B.; Zhao, H. Characterization of the substrate specificity of phld, a type III polyketide synthase from Pseudomonas fluorescens. J. Biol. Chem. 2006, 281, 32036-32047.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 32036-32047
-
-
Zha, W.1
Rubin-Pitel, S.B.2
Zhao, H.3
-
69
-
-
0942268922
-
Role of the active site cysteine of dpga, a bacterial type III polyketide synthase
-
Tseng, C.C.; McLoughlin, S.M.; Kelleher, N.L.; Walsh, C.T. Role of the active site cysteine of dpga, a bacterial type III polyketide synthase. Biochemistry 2004, 43, 970-980.
-
(2004)
Biochemistry
, vol.43
, pp. 970-980
-
-
Tseng, C.C.1
McLoughlin, S.M.2
Kelleher, N.L.3
Walsh, C.T.4
-
70
-
-
84859599611
-
Chain elongation and cyclization in type III pks dpga
-
Wu, H.-C.; Li, Y.-S.; Liu, Y.-C.; Lyu, S.-Y.; Wu, C.-J.; Li, T.-L. Chain elongation and cyclization in type III pks dpga. ChemBioChem Eur. J. Chem. Biol. 2012, 13, 862-871.
-
(2012)
ChemBioChem Eur. J. Chem. Biol.
, vol.13
, pp. 862-871
-
-
Wu, H.-C.1
Li, Y.-S.2
Liu, Y.-C.3
Lyu, S.-Y.4
Wu, C.-J.5
Li, T.-L.6
-
71
-
-
0242666130
-
A new family of type III polyketide synthases in Mycobacterium tuberculosis
-
Saxena, P.; Yadav, G.; Mohanty, D.; Gokhale, R.S. A new family of type III polyketide synthases in Mycobacterium tuberculosis. J. Biol. Chem. 2003, 278, 44780-44790.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44780-44790
-
-
Saxena, P.1
Yadav, G.2
Mohanty, D.3
Gokhale, R.S.4
-
72
-
-
4344585355
-
A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites
-
Sankaranarayanan, R.; Saxena, P.; Marathe, U.B.; Gokhale, R.S.; Shanmugam, V.M.; Rukmini, R. A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites. Nat. Struct. Mol. Biol. 2004, 11, 894-900.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 894-900
-
-
Sankaranarayanan, R.1
Saxena, P.2
Marathe, U.B.3
Gokhale, R.S.4
Shanmugam, V.M.5
Rukmini, R.6
-
73
-
-
84878756904
-
Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (pks11) reveals intermediates in the synthesis of methyl-branched alkylpyrones
-
Gokulan, K.; O'Leary, S.E.; Russell, W.K.; Russell, D.H.; Lalgondar, M.; Begley, T.P.; Ioerger, T.R.; Sacchettini, J.C. Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (pks11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. J. Biol. Chem. 2013, 288, 16484-16494.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 16484-16494
-
-
Gokulan, K.1
O'Leary, S.E.2
Russell, W.K.3
Russell, D.H.4
Lalgondar, M.5
Begley, T.P.6
Ioerger, T.R.7
Sacchettini, J.C.8
-
74
-
-
33845212858
-
Type III polyketide synthase beta-ketoacyl-acp starter unit and ethylmalonyl-coa extender unit selectivity discovered by Streptomyces coelicolor genome mining
-
Song, L.; Barona-Gomez, F.; Corre, C.; Xiang, L.; Udwary, D.W.; Austin, M.B.; Noel, J.P.; Moore, B.S.; Challis, G.L. Type III polyketide synthase beta-ketoacyl-acp starter unit and ethylmalonyl-coa extender unit selectivity discovered by Streptomyces coelicolor genome mining. J. Am. Chem. Soc. 2006, 128, 14754-14755.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 14754-14755
-
-
Song, L.1
Barona-Gomez, F.2
Corre, C.3
Xiang, L.4
Udwary, D.W.5
Austin, M.B.6
Noel, J.P.7
Moore, B.S.8
Challis, G.L.9
-
75
-
-
34447521692
-
Substrate profile analysis and acp-mediated acyl transfer in Streptomyces coelicolor type III polyketide synthases
-
Gruschow, S.; Buchholz, T.J.; Seufert, W.; Dordick, J.S.; Sherman, D.H. Substrate profile analysis and acp-mediated acyl transfer in Streptomyces coelicolor type III polyketide synthases. ChemBioChem Eur. J. Chem. Biol. 2007, 8, 863-868.
-
(2007)
ChemBioChem Eur. J. Chem. Biol.
, vol.8
, pp. 863-868
-
-
Gruschow, S.1
Buchholz, T.J.2
Seufert, W.3
Dordick, J.S.4
Sherman, D.H.5
-
76
-
-
84860810079
-
Biochemical and structural characterization of germicidin synthase: Analysis of a type III polyketide synthase that employs acyl-acp as a starter unit donor
-
Chemler, J.A.; Buchholz, T.J.; Geders, T.W.; Akey, D.L.; Rath, C.M.; Chlipala, G.E.; Smith, J.L.; Sherman, D.H. Biochemical and structural characterization of germicidin synthase: Analysis of a type III polyketide synthase that employs acyl-acp as a starter unit donor. J. Am. Chem. Soc. 2012, 134, 7359-7366.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 7359-7366
-
-
Chemler, J.A.1
Buchholz, T.J.2
Geders, T.W.3
Akey, D.L.4
Rath, C.M.5
Chlipala, G.E.6
Smith, J.L.7
Sherman, D.H.8
-
77
-
-
84868136536
-
A type III polyketide synthase from Rhizobium etli condenses malonyl coas to a heptaketide pyrone with unusually high catalytic efficiency
-
Jeya, M.; Kim, T.S.; Tiwari, M.K.; Li, J.; Zhao, H.; Lee, J.K. A type III polyketide synthase from Rhizobium etli condenses malonyl coas to a heptaketide pyrone with unusually high catalytic efficiency. Mol. BioSyst. 2012, 8, 3103-3106.
-
(2012)
Mol. BioSyst.
, vol.8
, pp. 3103-3106
-
-
Jeya, M.1
Kim, T.S.2
Tiwari, M.K.3
Li, J.4
Zhao, H.5
Lee, J.K.6
-
78
-
-
33646557702
-
Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandii
-
Funa, N.; Ozawa, H.; Hirata, A.; Horinouchi, S. Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandii. Proc. Natl. Acad. Sci. USA 2006, 103, 6356-6361.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6356-6361
-
-
Funa, N.1
Ozawa, H.2
Hirata, A.3
Horinouchi, S.4
-
79
-
-
38949095007
-
Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis
-
Miyanaga, A.; Funa, N.; Awakawa, T.; Horinouchi, S. Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis. Proc. Natl. Acad. Sci. USA 2008, 105, 871-876.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 871-876
-
-
Miyanaga, A.1
Funa, N.2
Awakawa, T.3
Horinouchi, S.4
-
80
-
-
84888332550
-
Structural basis for cyclization specificity of two azotobacter type III polyketide synthases: A single amino acid substitution reverses their cyclization specificity
-
Satou, R.; Miyanaga, A.; Ozawa, H.; Funa, N.; Katsuyama, Y.; Miyazono, K.; Tanokura, M.; Ohnishi, Y.; Horinouchi, S. Structural basis for cyclization specificity of two azotobacter type III polyketide synthases: A single amino acid substitution reverses their cyclization specificity. J. Biol. Chem. 2013, 288, 34146-34157.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 34146-34157
-
-
Satou, R.1
Miyanaga, A.2
Ozawa, H.3
Funa, N.4
Katsuyama, Y.5
Miyazono, K.6
Tanokura, M.7
Ohnishi, Y.8
Horinouchi, S.9
-
81
-
-
84878012494
-
4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum
-
Awakawa, T.; Sugai, Y.; Otsutomo, K.; Ren, S.; Masuda, S.; Katsuyama, Y.; Horinouchi, S.; Ohnishi, Y. 4-hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. ChemBioChem Eur. J. Chem. Biol. 2013, 14, 1006-1013.
-
(2013)
ChemBioChem Eur. J. Chem. Biol.
, vol.14
, pp. 1006-1013
-
-
Awakawa, T.1
Sugai, Y.2
Otsutomo, K.3
Ren, S.4
Masuda, S.5
Katsuyama, Y.6
Horinouchi, S.7
Ohnishi, Y.8
-
82
-
-
77950557137
-
Type III polyketide synthases in lichen mycobionts
-
Muggia, L.; Grube, M. Type III polyketide synthases in lichen mycobionts. Fungal Biol. 2010, 114, 379-385.
-
(2010)
Fungal Biol.
, vol.114
, pp. 379-385
-
-
Muggia, L.1
Grube, M.2
-
83
-
-
44549087965
-
Structural insights into biosynthesis of resorcinolic lipids by a type III polyketide synthase in Neurospora crassa
-
Goyal, A.; Saxena, P.; Rahman, A.; Singh, P.K.; Kasbekar, D.P.; Gokhale, R.S.; Sankaranarayanan, R. Structural insights into biosynthesis of resorcinolic lipids by a type III polyketide synthase in Neurospora crassa. J. Struct. Biol. 2008, 162, 411-421.
-
(2008)
J. Struct. Biol.
, vol.162
, pp. 411-421
-
-
Goyal, A.1
Saxena, P.2
Rahman, A.3
Singh, P.K.4
Kasbekar, D.P.5
Gokhale, R.S.6
Sankaranarayanan, R.7
-
84
-
-
53649092534
-
Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa
-
Rubin-Pitel, S.B.; Zhang, H.; Vu, T.; Brunzelle, J.S.; Zhao, H.; Nair, S.K. Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa. Chem. Biol. 2008, 15, 1079-1090.
-
(2008)
Chem. Biol.
, vol.15
, pp. 1079-1090
-
-
Rubin-Pitel, S.B.1
Zhang, H.2
Vu, T.3
Brunzelle, J.S.4
Zhao, H.5
Nair, S.K.6
-
85
-
-
84907152022
-
Fungal type III polyketide synthases
-
Hashimoto, M.; Nonaka, T.; Fujii, I. Fungal type III polyketide synthases. Nat. Prod. Rep. 2014, 31, 1306-1317.
-
(2014)
Nat. Prod. Rep.
, vol.31
, pp. 1306-1317
-
-
Hashimoto, M.1
Nonaka, T.2
Fujii, I.3
-
86
-
-
84904490513
-
Aspergillus oryzae csyb catalyzes the condensation of two beta-ketoacyl-coas to form 3-acetyl-4-hydroxy-6-alkyl-alpha-pyrone
-
Hashimoto, M.; Koen, T.; Takahashi, H.; Suda, C.; Kitamoto, K.; Fujii, I. Aspergillus oryzae csyb catalyzes the condensation of two beta-ketoacyl-coas to form 3-acetyl-4-hydroxy-6-alkyl-alpha-pyrone. J. Biol. Chem. 2014, 289, 19976-19984.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 19976-19984
-
-
Hashimoto, M.1
Koen, T.2
Takahashi, H.3
Suda, C.4
Kitamoto, K.5
Fujii, I.6
-
87
-
-
84867388800
-
The Botrytis cinerea type III polyketide synthase shows unprecedented high catalytic efficiency toward long chain acyl-coas
-
Jeya, M.; Kim, T.S.; Tiwari, M.K.; Li, J.; Zhao, H.; Lee, J.K. The Botrytis cinerea type III polyketide synthase shows unprecedented high catalytic efficiency toward long chain acyl-coas. Mol. BioSyst. 2012, 8, 2864-2867.
-
(2012)
Mol. BioSyst.
, vol.8
, pp. 2864-2867
-
-
Jeya, M.1
Kim, T.S.2
Tiwari, M.K.3
Li, J.4
Zhao, H.5
Lee, J.K.6
-
88
-
-
84928485394
-
Allantopyrone a, an α-pyrone metabolite from an endophytic fungus, inhibits the tumor necrosis factor α-induced nuclear factor kappab signaling pathway
-
Yokoigawa, J.; Morimoto, K.; Shiono, Y.; Uesugi, S.; Kimura, K.I.; Kataoka, T. Allantopyrone a, an α-pyrone metabolite from an endophytic fungus, inhibits the tumor necrosis factor α-induced nuclear factor kappab signaling pathway. J. Antibiot. 2015, 68, 71-75.
-
(2015)
J. Antibiot.
, vol.68
, pp. 71-75
-
-
Yokoigawa, J.1
Morimoto, K.2
Shiono, Y.3
Uesugi, S.4
Kimura, K.I.5
Kataoka, T.6
-
89
-
-
84901487802
-
Antibacterial α-pyrone derivatives from a mangrove-derived fungus Stemphylium sp. 33231 from the south China sea
-
Zhou, X.M.; Zheng, C.J.; Song, X.P.; Han, C.R.; Chen, W.H.; Chen, G.Y. Antibacterial α-pyrone derivatives from a mangrove-derived fungus Stemphylium sp. 33231 from the south China sea. J. Antibiot. 2014, 67, 401-403.
-
(2014)
J. Antibiot.
, vol.67
, pp. 401-403
-
-
Zhou, X.M.1
Zheng, C.J.2
Song, X.P.3
Han, C.R.4
Chen, W.H.5
Chen, G.Y.6
-
90
-
-
0038004465
-
Enzymatic formation of unnatural novel polyketides from alternate starter and nonphysiological extension substrate by chalcone synthase
-
Abe, I.; Takahashi, Y.; Lou, W.; Noguchi, H. Enzymatic formation of unnatural novel polyketides from alternate starter and nonphysiological extension substrate by chalcone synthase. Org. Lett. 2003, 5, 1277-1280.
-
(2003)
Org. Lett.
, vol.5
, pp. 1277-1280
-
-
Abe, I.1
Takahashi, Y.2
Lou, W.3
Noguchi, H.4
-
91
-
-
0036834321
-
Molecular characterization of root-specific chalcone synthases from Cassia alata
-
Samappito, S.; Page, J.; Schmidt, J.; De-Eknamkul, W.; Kutchan, T.M. Molecular characterization of root-specific chalcone synthases from Cassia alata. Planta 2002, 216, 64-71.
-
(2002)
Planta
, vol.216
, pp. 64-71
-
-
Samappito, S.1
Page, J.2
Schmidt, J.3
De-Eknamkul, W.4
Kutchan, T.M.5
-
92
-
-
0034819358
-
Novel polyketides synthesized with a higher plant stilbene synthase
-
Morita, H.; Noguchi, H.; Schroder, J.; Abe, I. Novel polyketides synthesized with a higher plant stilbene synthase. Eur. J. Biochem. 2001, 268, 3759-3766.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 3759-3766
-
-
Morita, H.1
Noguchi, H.2
Schroder, J.3
Abe, I.4
-
93
-
-
65549136582
-
Identification of a pentaketide stilbene produced by a type III polyketide synthase from pinus sylvestris and characterisation of free coenzyme a intermediates
-
Li, T.L.; Spiteller, D.; Spencer, J.B. Identification of a pentaketide stilbene produced by a type III polyketide synthase from pinus sylvestris and characterisation of free coenzyme a intermediates. ChemBioChem Eur. J. Chem. Biol. 2009, 10, 896-901.
-
(2009)
ChemBioChem Eur. J. Chem. Biol.
, vol.10
, pp. 896-901
-
-
Li, T.L.1
Spiteller, D.2
Spencer, J.B.3
-
94
-
-
60849085462
-
Enzymatic formation of unnatural novel chalcone, stilbene, and benzophenone scaffolds by plant type III polyketide synthase
-
Shi, S.-P.; Wanibuchi, K.; Morita, H.; Endo, K.; Noguchi, H.; Abe, I. Enzymatic formation of unnatural novel chalcone, stilbene, and benzophenone scaffolds by plant type III polyketide synthase. Org. Lett. 2009, 11, 551-554.
-
(2009)
Org. Lett.
, vol.11
, pp. 551-554
-
-
Shi, S.-P.1
Wanibuchi, K.2
Morita, H.3
Endo, K.4
Noguchi, H.5
Abe, I.6
-
95
-
-
49349090382
-
Octaketide-producing type III polyketide synthase from hypericum perforatum is expressed in dark glands accumulating hypericins
-
Karppinen, K.; Hokkanen, J.; Mattila, S.; Neubauer, P.; Hohtola, A. Octaketide-producing type III polyketide synthase from hypericum perforatum is expressed in dark glands accumulating hypericins. FEBS J. 2008, 275, 4329-4342.
-
(2008)
FEBS J.
, vol.275
, pp. 4329-4342
-
-
Karppinen, K.1
Hokkanen, J.2
Mattila, S.3
Neubauer, P.4
Hohtola, A.5
-
96
-
-
33846120941
-
Enzymatic formation of quinolone alkaloids by a plant type III polyketide synthase
-
Abe, I.; Abe, T.; Wanibuchi, K.; Noguchi, H. Enzymatic formation of quinolone alkaloids by a plant type III polyketide synthase. Org. Lett. 2006, 8, 6063-6065.
-
(2006)
Org. Lett.
, vol.8
, pp. 6063-6065
-
-
Abe, I.1
Abe, T.2
Wanibuchi, K.3
Noguchi, H.4
-
97
-
-
79953855889
-
Cytotoxic tetramic acid derivative produced by a plant type-III polyketide synthase
-
Wakimoto, T.; Mori, T.; Morita, H.; Abe, I. Cytotoxic tetramic acid derivative produced by a plant type-III polyketide synthase. J. Am. Chem. Soc. 2011, 133, 4746-4749.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 4746-4749
-
-
Wakimoto, T.1
Mori, T.2
Morita, H.3
Abe, I.4
-
98
-
-
84861905297
-
Establishing a toolkit for precursor-directed polyketide biosynthesis: Exploring substrate promiscuities of acid-coa ligases
-
Go, M.K.; Chow, J.Y.; Cheung, V.W.; Lim, Y.P.; Yew, W.S. Establishing a toolkit for precursor-directed polyketide biosynthesis: Exploring substrate promiscuities of acid-coa ligases. Biochemistry 2012, 51, 4568-4579.
-
(2012)
Biochemistry
, vol.51
, pp. 4568-4579
-
-
Go, M.K.1
Chow, J.Y.2
Cheung, V.W.3
Lim, Y.P.4
Yew, W.S.5
-
99
-
-
71449089781
-
A single amino acid substitution converts benzophenone synthase into phenylpyrone synthase
-
Klundt, T.; Bocola, M.; Lutge, M.; Beuerle, T.; Liu, B.; Beerhues, L. A single amino acid substitution converts benzophenone synthase into phenylpyrone synthase. J. Biol. Chem. 2009, 284, 30957-30964.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30957-30964
-
-
Klundt, T.1
Bocola, M.2
Lutge, M.3
Beuerle, T.4
Liu, B.5
Beerhues, L.6
-
100
-
-
0037117475
-
Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity
-
Jez, J.M.; Bowman, M.E.; Noel, J.P. Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity. Proc. Natl. Acad. Sci. USA 2002, 99, 5319-5324.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5319-5324
-
-
Jez, J.M.1
Bowman, M.E.2
Noel, J.P.3
-
101
-
-
32644439876
-
Engineered biosynthesis of plant polyketides - Manipulation of chalcone synthase
-
Abe, I.; Watanabe, T.; Morita, H.; Kohno, T.; Noguchi, H. Engineered biosynthesis of plant polyketides - Manipulation of chalcone synthase. Org. Lett. 2006, 8, 499-502.
-
(2006)
Org. Lett.
, vol.8
, pp. 499-502
-
-
Abe, I.1
Watanabe, T.2
Morita, H.3
Kohno, T.4
Noguchi, H.5
-
102
-
-
34248526212
-
Structure-based engineering of a plant type III polyketide synthase: Formation of an unnatural nonaketide naphthopyrone
-
Abe, I.; Morita, H.; Oguro, S.; Noma, H.; Wanibuchi, K.; Kawahara, N.; Goda, Y.; Noguchi, H.; Kohno, T. Structure-based engineering of a plant type III polyketide synthase: Formation of an unnatural nonaketide naphthopyrone. J. Am. Chem. Soc. 2007, 129, 5976-5980.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 5976-5980
-
-
Abe, I.1
Morita, H.2
Oguro, S.3
Noma, H.4
Wanibuchi, K.5
Kawahara, N.6
Goda, Y.7
Noguchi, H.8
Kohno, T.9
-
103
-
-
78649358322
-
Engineered biosynthesis of plant polyketides: Structure-based and precursor-directed approach
-
Abe, I. Engineered biosynthesis of plant polyketides: Structure-based and precursor-directed approach. Top. Curr. Chem. 2010, 297, 45-66.
-
(2010)
Top. Curr. Chem.
, vol.297
, pp. 45-66
-
-
Abe, I.1
-
104
-
-
79952490291
-
Enzymatic formation of an aromatic dodecaketide by engineered plant polyketide synthase
-
Wanibuchi, K.; Morita, H.; Noguchi, H.; Abe, I. Enzymatic formation of an aromatic dodecaketide by engineered plant polyketide synthase. Bioorg. Med. Chem. Lett. 2011, 21, 2083-2086.
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 2083-2086
-
-
Wanibuchi, K.1
Morita, H.2
Noguchi, H.3
Abe, I.4
-
105
-
-
80051986672
-
Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase
-
Morita, H.; Yamashita, M.; Shi, S.P.; Wakimoto, T.; Kondo, S.; Kato, R.; Sugio, S.; Kohno, T.; Abe, I. Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase. Proc. Natl. Acad. Sci. USA 2011, 108, 13504-13509.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 13504-13509
-
-
Morita, H.1
Yamashita, M.2
Shi, S.P.3
Wakimoto, T.4
Kondo, S.5
Kato, R.6
Sugio, S.7
Kohno, T.8
Abe, I.9
-
106
-
-
0036844888
-
Alteration of reaction and substrate specificity of a bacterial type III polyketide synthase by site-directed mutagenesis
-
Funa, N.; Ohnishi, Y.; Ebizuka, Y.; Horinouchi, S. Alteration of reaction and substrate specificity of a bacterial type III polyketide synthase by site-directed mutagenesis. Biochem. J. 2002, 367, 781-789.
-
(2002)
Biochem. J.
, vol.367
, pp. 781-789
-
-
Funa, N.1
Ohnishi, Y.2
Ebizuka, Y.3
Horinouchi, S.4
-
107
-
-
34250325921
-
Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor rppa, a bacterial type III polyketide synthase
-
Li, S.; Gruschow, S.; Dordick, J.S.; Sherman, D.H. Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor rppa, a bacterial type III polyketide synthase. J. Biol. Chem. 2007, 282, 12765-12772.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12765-12772
-
-
Li, S.1
Gruschow, S.2
Dordick, J.S.3
Sherman, D.H.4
|