An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases

Chemistry and Biology

Volumn 11, Issue 9, 2004, Pages 1179-1194

  Austin, Michael B ^a,b   Bowman, Marianne E ^a   Ferrer, Jean Luc ^c   Schröder, Joachim ^d   Noel, Joseph P ^a,b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CHALCONE SYNTHASE; RESVERATROL; STILBENE DERIVATIVE; STILBENE SYNTHASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ACYLTRANSFERASES; AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; STILBENES; SUBSTRATE SPECIFICITY;

MEDICAGO SATIVA;

EID: 4644270018     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.05.024     Document Type: Article

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