Synthetic Polyketide Enzymology: Platform for Biosynthesis of Antimicrobial Polyketides

ACS Catalysis

Volumn 5, Issue 7, 2015, Pages 4033-4042

  Go, Maybelle Kho ^a,b   Wongsantichon, Jantana ^c   Cheung, Vivian Wing Ngar ^a,b   Chow, Jeng Yeong ^a   Robinson, Robert C ^a,c   Yew, Wen Shan ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

anti microbials; platform for synthetic biology; polyketides; precursor directed combinatorial biosynthesis; synthetic enzymology; therapeutics development

Indexed keywords

BACTERIA; BIOCHEMISTRY; BIOLOGY; BIOSYNTHESIS; ENZYMES; MICROORGANISMS; MOLECULAR BIOLOGY; PLANTS (BOTANY);

COMBINATORIAL BIOSYNTHESIS; MICROBIALS; POLYKETIDES; SYNTHETIC BIOLOGY; SYNTHETIC ENZYMOLOGY; THERAPEUTICS DEVELOPMENT;

KETONES;

EID: 84946150258     PISSN: 21555435     EISSN: None     Source Type: Journal    
DOI: 10.1021/acscatal.5b00477     Document Type: Article

References (19)

1. Dixon, R. A. Nature 2001, 411, 843 10.1038/35081178
2. Staunton, J.; Weissman, K. J. Nat. Prod. Rep. 2001, 18, 380 10.1039/a909079g
3. Yu, D.; Xu, F.; Zeng, J.; Zhan, J. IUBMB Life 2012, 64, 285 10.1002/iub.1005
4. Go, M. K.; Chow, J. Y.; Cheung, V. W. N.; Lim, Y. P.; Yew, W. S. Biochemistry 2012, 51, 4568 10.1021/bi300425j
5. Kim, M. I.; Kwon, S. J.; Dordick, J. S. Org. Lett. 2009, 11, 3806 10.1021/ol901243e
6. Ferrer, J. L.; Jez, J. M.; Bowman, M. E.; Dixon, R. A.; Noel, J. P. Nat. Struct. Biol. 1999, 6, 775 10.1038/11553
7. Abe, I.; Morita, H. Nat. Prod. Rep. 2010, 27, 809 10.1039/b909988n
8. Beuerle, T.; Pichersky, E. Anal. Biochem. 2002, 302, 305 10.1006/abio.2001.5574
9. Egland, P. G.; Gibson, J.; Harwood, C. S. Journal of bacteriology 1995, 177, 6545
10. Katsuyama, Y.; Funa, N.; Miyahisa, I.; Horinouchi, S. Chem. Biol. 2007, 14, 613 10.1016/j.chembiol.2007.05.004
11. McCoy, A. J.; Grosse-Kunstleve, R. W.; Adams, P. D.; Winn, M. D.; Storoni, L. C.; Read, R. J. J. Appl. Crystallogr. 2007, 40, 658 10.1107/S0021889807021206
12. Murshudov, G. N.; Vagin, A. A.; Dodson, E. J. Acta Crystallogr., Sect. D: Biol. Crystallogr. 1997, 53, 240 10.1107/S0907444996012255
13. Emsley, P.; Lohkamp, B.; Scott, W. G.; Cowtan, K. Acta Crystallogr., Sect. D: Biol. Crystallogr. 2010, 66, 486 10.1107/S0907444910007493
14. Abe, I.; Watanabe, T.; Morita, H.; Kohno, T.; Noguchi, H. Org. Lett. 2006, 8, 499 10.1021/ol052912h
15. Benedict, R. G.; Brady, L. R. J. Pharm. Sci. 1972, 61, 1820 10.1002/jps.2600611130
16. Cueva, C.; Moreno-Arribas, M. V.; Martin-Alvarez, P. J.; Bills, G.; Vicente, M. F.; Basilio, A.; Rivas, C. L.; Requena, T.; Rodriguez, J. M.; Bartolome, B. Res. Microbiol. 2010, 161, 372 10.1016/j.resmic.2010.04.006
17. Keweloh, H.; Weyrauch, G.; Rehm, H. J. Appl. Microbiol. Biotechnol. 1990, 33, 66 10.1007/BF00170572
18. Choi, S. H.; Gu, M. B. Environ. Toxicol. Chem. 2001, 20, 248 10.1002/etc.5620200204
19. Vattem, D. A.; Lin, Y. T.; Ghaedian, R.; Shetty, K. Process Biochem. 2005, 40, 1583 10.1016/j.procbio.2004.06.024