Transforming growth factor β1 (TGF-β1) activates hepcidin mRNA expression in hepatocytes

Journal of Biological Chemistry

Volumn 291, Issue 25, 2016, Pages 13160-13174

  Chen, Simeng ^a,b   Feng, Teng ^a   Spasić, Maja Vujiæ ^a   Altamura, Sandro ^b   Breitkopf Heinlein, Katja ^a,b   Altenö, Jutta ^a   Weiss, Thomas S ^a   Dooley, Steven ^c   Muckenthaler, Martina U ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Molecular Medicine Partnership Unit   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX NETWORKS; CROSSTALK; ENZYME INHIBITION; IRON; IRON COMPOUNDS; MAMMALS;

BONE MORPHOGENETIC PROTEINS; COMPLEX REGULATORY NETWORK; ECTOPIC EXPRESSIONS; HUMAN HEPATOCYTES; SIGNALING COMPONENTS; SIGNALING PROTEINS; TRANSFERRIN RECEPTORS; TRANSFORMING GROWTH FACTORS;

PROTEINS;

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 6; HEMOGLOBIN; HEMOJUVELIN; HEPCIDIN; MESSENGER RNA; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFERRIN RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; BMP6 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SMAD PROTEIN; TGF-BETA TYPE I RECEPTOR; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DOWN REGULATION; GENE LOCUS; HEMATOCRIT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IRON METABOLISM; IRON OVERLOAD; LIVER CELL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; FEMALE; GENE EXPRESSION; GENETICS; MALE; METABOLISM; PHYSIOLOGY; PRIMARY CELL CULTURE; TRANSCRIPTION INITIATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 6; CELLS, CULTURED; FEMALE; GENE EXPRESSION; HEPATOCYTES; HEPCIDINS; MALE; MICE; MICE, INBRED C57BL; PRIMARY CELL CULTURE; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSCRIPTIONAL ACTIVATION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84975068626     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.691543     Document Type: Article

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