A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

Journal of Molecular Medicine

Volumn 86, Issue 5, 2008, Pages 531-540

  Verga Falzacappa, Maria Vittoria ^a   Casanovas, Guillem ^a,b   Hentze, Matthias W ^b   Muckenthaler, Martina U ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

BMP; Hepcidin; HFE2; IL 6; Promoter; STAT 3

Indexed keywords

BONE MORPHOGENETIC PROTEIN; HEMOJUVELIN; HEPCIDIN; INTERLEUKIN 6; LIVER PROTEIN; MESSENGER RNA;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIVER CELL; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA SYNTHESIS; SIGNAL TRANSDUCTION;

ANTIMICROBIAL CATIONIC PEPTIDES; BASE PAIRING; BASE SEQUENCE; BONE MORPHOGENETIC PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; LIVER; MEMBRANE PROTEINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; RESPONSE ELEMENTS; RNA, MESSENGER; RNA, SMALL INTERFERING; STAT3 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 43049132128     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0313-7     Document Type: Article

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