The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

Journal of Hepatology

Volumn 57, Issue 5, 2012, Pages 1052-1060

  D'Alessio, Flavia ^a,b   Hentze, Matthias W ^b,c   Muckenthaler, Martina U ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Molecular Medicine Partnership Unit (MMPU)   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

BMP SMAD pathway; Hereditary hemochromatosis; Iron sensing

Indexed keywords

AMINO ACID; BONE MORPHOGENETIC PROTEIN; HEPCIDIN; HFE PROTEIN; IRON; MEMBRANE PROTEIN; PROTEIN HJV; PROTEIN TFR2; SMAD PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BINDING COMPETITION; CELL SURFACE; CENTRAL NERVOUS SYSTEM; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; GLYCEROL GRADIENT SEDIMENTATION ASSAY; HEMOCHROMATOSIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIVER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMINO ACIDS; ANTIMICROBIAL CATIONIC PEPTIDES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; GPI-LINKED PROTEINS; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LIVER NEOPLASMS; MEMBRANE PROTEINS; MULTIPROTEIN COMPLEXES; NERVE TISSUE PROTEINS; PROTEIN BINDING; RECEPTORS, TRANSFERRIN; SIGNAL TRANSDUCTION;

EID: 84867578495     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.06.015     Document Type: Article

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