-
1
-
-
77954249308
-
Two to tango: Regulation of Mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, Galy B, Camaschella C. Two to tango: regulation of Mammalian iron metabolism. Cell. 2010;142(1):24-38.
-
(2010)
Cell
, vol.142
, Issue.1
, pp. 24-38
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Galy, B.3
Camaschella, C.4
-
2
-
-
0034284595
-
LEAP-1, a novel highly disulfidebonded human peptide, exhibits antimicrobial activity
-
Krause A, et al. LEAP-1, a novel highly disulfidebonded human peptide, exhibits antimicrobial activity. FEBS Lett. 2000;480(2-3):147-150.
-
(2000)
FEBS Lett
, vol.480
, Issue.2-3
, pp. 147-150
-
-
Krause, A.1
-
3
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem. 2001;276(11):7806-7810.
-
(2001)
J Biol Chem
, vol.276
, Issue.11
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
4
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
DOI 10.1126/science.1104742
-
Nemeth E, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306(5704):2090-2093. (Pubitemid 40007660)
-
(2004)
Science
, vol.306
, Issue.5704
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.D.4
Donovan, A.5
Ward, D.M.6
Ganz, T.7
Kaplan, J.8
-
5
-
-
42649118442
-
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
-
DOI 10.1038/ng.130, PII NG130
-
Finberg KE, et al. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet. 2008;40(5):569-571. (Pubitemid 351601217)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 569-571
-
-
Finberg, K.E.1
Heeney, M.M.2
Campagna, D.R.3
Aydinok, Y.4
Pearson, H.A.5
Hartman, K.R.6
Mayo, M.M.7
Samuel, S.M.8
Strouse, J.J.9
Markianos, K.10
Andrews, N.C.11
Fleming, M.D.12
-
7
-
-
34447306076
-
Liver iron concentrations and urinary hepcidin in beta-thalassemia
-
DOI 10.3324/haematol.10842
-
Origa R, et al. Liver iron concentrations and urinary hepcidin in beta-thalassemia. Haematologica. 2007;92(5):583-588. (Pubitemid 350144260)
-
(2007)
Haematologica
, vol.92
, Issue.5
, pp. 583-588
-
-
Origa, R.1
Galanello, R.2
Ganz, T.3
Giagu, N.4
Maccioni, L.5
Faa, G.6
Nemeth, E.7
-
8
-
-
0037509928
-
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
-
DOI 10.1038/ng1152
-
Muckenthaler M, et al. Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nat Genet. 2003;34(1):102-107. (Pubitemid 36548799)
-
(2003)
Nature Genetics
, vol.34
, Issue.1
, pp. 102-107
-
-
Muckenthaler, M.1
Roy, C.N.2
Custodio, A.O.3
Minana, B.4
DeGraaf, J.5
Montross, L.K.6
Andrews, N.C.7
Hentze, M.W.8
-
9
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
DOI 10.1016/S0140-6736(03)12602-5
-
Bridle KR, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet. 2003;361(9358):669-673. (Pubitemid 36246550)
-
(2003)
Lancet
, vol.361
, Issue.9358
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
Dixon, J.L.4
Purdie, D.M.5
Crawford, D.H.G.6
Subramaniam, V.N.7
Powell, L.W.8
Anderson, G.J.9
Ramm, G.A.10
-
10
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
DOI 10.1038/ng1274
-
Papanikolaou G, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet. 2004;36(1):77-82. (Pubitemid 38056211)
-
(2004)
Nature Genetics
, vol.36
, Issue.1
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
MacDonald, M.L.E.4
Franchini, P.L.5
Dube, M.-P.6
Andres, L.7
MacFarlane, J.8
Sakellaropoulos, N.9
Politou, M.10
Nemeth, E.11
Thompson, J.12
Risler, J.K.13
Zaborowska, C.14
Babakaiff, R.15
Radomski, C.C.16
Pape, T.D.17
Davidas, O.18
Christakis, J.19
Brissot, P.20
Lockitch, G.21
Ganz, T.22
Hayden, M.R.23
Goldberg, Y.P.24
more..
-
11
-
-
23644460325
-
A mouse model of juvenile hemochromatosis
-
DOI 10.1172/JCI25049
-
Huang FW, Pinkus JL, Pinkus GS, Fleming MD, Andrews NC. A mouse model of juvenile hemochromatosis. J Clin Invest. 2005;115(8):2187-2191. (Pubitemid 41134160)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2187-2191
-
-
Huang, F.W.1
Pinkus, J.L.2
Pinkus, G.S.3
Fleming, M.D.4
Andrews, N.C.5
-
12
-
-
23644444316
-
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
-
DOI 10.1172/JCI25683
-
Niederkofler V, Salie R, Arber S. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J Clin Invest. 2005;115(8):2180-2186. (Pubitemid 41134159)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2180-2186
-
-
Niederkofler, V.1
Salie, R.2
Arber, S.3
-
13
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
DOI 10.1038/75534
-
Camaschella C, et al. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat Genet. 2000;25(1):14-15. (Pubitemid 30257027)
-
(2000)
Nature Genetics
, vol.25
, Issue.1
, pp. 14-15
-
-
Camaschella, C.1
Roetto, A.2
Cali, A.3
De Gobbi, M.4
Garozzo, G.5
Carella, M.6
Majorano, N.7
Totaro, A.8
Gasparini, P.9
-
14
-
-
0036678091
-
Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis
-
Fleming RE, et al. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis. Proc Natl Acad Sci U S A. 2002; 99(16):10653-10658.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.16
, pp. 10653-10658
-
-
Fleming, R.E.1
-
15
-
-
63449103712
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
-
Andriopoulos B Jr, et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41(4):482-487.
-
(2009)
Nat Genet
, vol.41
, Issue.4
, pp. 482-487
-
-
Andriopoulos Jr., B.1
-
16
-
-
63449122819
-
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
-
Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP. Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet. 2009;41(4):478-481.
-
(2009)
Nat Genet
, vol.41
, Issue.4
, pp. 478-481
-
-
Meynard, D.1
Kautz, L.2
Darnaud, V.3
Canonne-Hergaux, F.4
Coppin, H.5
Roth, M.P.6
-
17
-
-
67349204418
-
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
-
Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU. Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. J Mol Med. 2009;87(5):471-480.
-
(2009)
J Mol Med
, vol.87
, Issue.5
, pp. 471-480
-
-
Casanovas, G.1
Mleczko-Sanecka, K.2
Altamura, S.3
Hentze, M.W.4
Muckenthaler, M.U.5
-
18
-
-
33644876815
-
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
-
Wang RH, et al. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab. 2005;2(6):399-409.
-
(2005)
Cell Metab
, vol.2
, Issue.6
, pp. 399-409
-
-
Wang, R.H.1
-
19
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
DOI 10.1172/JCI200420945
-
Nemeth E, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113(9):1271-1276. (Pubitemid 39069926)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.9
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
Keller, C.4
Taudorf, S.5
Pedersen, B.K.6
Ganz, T.7
-
20
-
-
33745338485
-
MicroRNAs: A new class of regulatory genes affecting metabolism
-
DOI 10.1016/j.cmet.2006.05.009, PII S1550413106002002
-
Krutzfeldt J, Stoffel M. MicroRNAs: a new class of regulatory genes affecting metabolism. Cell Metab. 2006;4(1):9-12. (Pubitemid 43942256)
-
(2006)
Cell Metabolism
, vol.4
, Issue.1
, pp. 9-12
-
-
Krutzfeldt, J.1
Stoffel, M.2
-
21
-
-
34848837296
-
miRNAs Get an Early Start on Translational Silencing
-
Meister G. miRNAs Get an Early Start on Translational Silencing. Cell. 2007;131(1):25-28.
-
(2007)
Cell
, vol.131
, Issue.1
, pp. 25-28
-
-
Meister, G.1
-
22
-
-
33645119514
-
MicroRNAs direct rapid deadenylation of mRNA
-
Wu L, Fan J, Belasco JG. MicroRNAs direct rapid deadenylation of mRNA. Proc Natl Acad Sci U S A. 2006;103(11):4034-4039.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.11
, pp. 4034-4039
-
-
Wu, L.1
Fan, J.2
Belasco, J.G.3
-
23
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15-20. (Pubitemid 40094598)
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
24
-
-
31044444975
-
TarBase: A comprehensive database of experimentally supported animal microRNA targets
-
DOI 10.1261/rna.2239606
-
Sethupathy P, Corda B, Hatzigeorgiou AG. Tar- Base: A comprehensive database of experimentally supported animal microRNA targets. Rna. 2006;12(2):192-197. (Pubitemid 43121923)
-
(2006)
RNA
, vol.12
, Issue.2
, pp. 192-197
-
-
Sethupathy, P.1
Corda, B.2
Hatzigeorgiou, A.G.3
-
25
-
-
0037197803
-
Identification of tissue-specific MicroRNAs from mouse
-
DOI 10.1016/S0960-9822(02)00809-6, PII S0960982202008096
-
Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T. Identification of tissue- specific microRNAs from mouse. Curr Biol. 2002;12(9):735-739. (Pubitemid 34455427)
-
(2002)
Current Biology
, vol.12
, Issue.9
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
26
-
-
34250877841
-
A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
-
DOI 10.1016/j.cell.2007.04.040, PII S0092867407006046
-
Landgraf P, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell. 2007;129(7):1401-1414. (Pubitemid 46970709)
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1401-1414
-
-
Landgraf, P.1
Rusu, M.2
Sheridan, R.3
Sewer, A.4
Iovino, N.5
Aravin, A.6
Pfeffer, S.7
Rice, A.8
Kamphorst, A.O.9
Landthaler, M.10
Lin, C.11
Socci, N.D.12
Hermida, L.13
Fulci, V.14
Chiaretti, S.15
Foa, R.16
Schliwka, J.17
Fuchs, U.18
Novosel, A.19
Muller, R.-U.20
Schermer, B.21
Bissels, U.22
Inman, J.23
Phan, Q.24
Chien, M.25
Weir, D.B.26
Choksi, R.27
De Vita, G.28
Frezzetti, D.29
Trompeter, H.-I.30
Hornung, V.31
Teng, G.32
Hartmann, G.33
Palkovits, M.34
Di, L.R.35
Wernet, P.36
Macino, G.37
Rogler, C.E.38
Nagle, J.W.39
Ju, J.40
Papavasiliou, F.N.41
Benzing, T.42
Lichter, P.43
Tam, W.44
Brownstein, M.J.45
Bosio, A.46
Borkhardt, A.47
Russo, J.J.48
Sander, C.49
Zavolan, M.50
Tuschl, T.51
more..
-
27
-
-
67349240835
-
Primary biliary cirrhosis is associated with altered hepatic microRNA expression
-
Padgett KA, et al. Primary biliary cirrhosis is associated with altered hepatic microRNA expression. J Autoimmun. 2009;32(3-4):246-253.
-
(2009)
J Autoimmun
, vol.32
, Issue.3-4
, pp. 246-253
-
-
Padgett, K.A.1
-
28
-
-
33749479908
-
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
-
DOI 10.1002/jcb.20982
-
Kutay H, et al. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem. 2006;99(3):671-678. (Pubitemid 44521987)
-
(2006)
Journal of Cellular Biochemistry
, vol.99
, Issue.3
, pp. 671-678
-
-
Kutay, H.1
Bai, S.2
Datta, J.3
Motiwala, T.4
Pogribny, I.5
Frankel, W.6
Jacob, S.T.7
Ghoshal, K.8
-
29
-
-
39849108178
-
miR-122, a paradigm for the role of microRNAs in the liver
-
Girard M, Jacquemin E, Munnich A, Lyonnet S, Henrion-Caude A. miR-122, a paradigm for the role of microRNAs in the liver. J Hepatol. 2008;48(4):648-656.
-
(2008)
J Hepatol
, vol.48
, Issue.4
, pp. 648-656
-
-
Girard, M.1
Jacquemin, E.2
Munnich, A.3
Lyonnet, S.4
Henrion-Caude, A.5
-
30
-
-
33645075443
-
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau C, et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab. 2006;3(2):87-98.
-
(2006)
Cell Metab
, vol.3
, Issue.2
, pp. 87-98
-
-
Esau, C.1
-
31
-
-
40249106014
-
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
-
DOI 10.1093/nar/gkm1113
-
Elmen J, et al. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 2008;36(4):1153-1162. (Pubitemid 351330933)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.4
, pp. 1153-1162
-
-
Elmen, J.1
Lindow, M.2
Silahtaroglu, A.3
Bak, M.4
Christensen, M.5
Lind-Thomsen, A.6
Hedtjarn, M.7
Hansen, J.B.8
Hansen, H.F.9
Straarup, E.M.10
McCullagh, K.11
Kearney, P.12
Kauppinen, S.13
-
32
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt J, et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature. 2005;438(7068):685-689.
-
(2005)
Nature
, vol.438
, Issue.7068
, pp. 685-689
-
-
Krutzfeldt, J.1
-
33
-
-
34250645857
-
Positive and negative modulation of viral and cellular mRNAs by liver-specific microRNA miR-122
-
Jopling CL, Norman KL, Sarnow P. Positive and negative modulation of viral and cellular mRNAs by liver-specific microRNA miR-122. Cold Spring Harb Symp Quant Biol. 2006;71:369-376.
-
(2006)
Cold Spring Harb Symp Quant Biol
, vol.71
, pp. 369-376
-
-
Jopling, C.L.1
Norman, K.L.2
Sarnow, P.3
-
34
-
-
59149102171
-
Regulation of hepatitis C virus by microRNA- 122
-
Jopling CL. Regulation of hepatitis C virus by microRNA- 122. Biochem Soc Trans. 2008;36(pt 6):1220-1223.
-
(2008)
Biochem Soc Trans
, vol.36
, Issue.PART 6
, pp. 1220-1223
-
-
Jopling, C.L.1
-
35
-
-
58149333128
-
Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy
-
Sarasin-Filipowicz M, Krol J, Markiewicz I, Heim MH, Filipowicz W. Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat Med. 2009;15(1):31-33.
-
(2009)
Nat Med
, vol.15
, Issue.1
, pp. 31-33
-
-
Sarasin-Filipowicz, M.1
Krol, J.2
Markiewicz, I.3
Heim, M.H.4
Filipowicz, W.5
-
36
-
-
38649128515
-
Hfe Acts in Hepatocytes to Prevent Hemochromatosis
-
DOI 10.1016/j.cmet.2007.11.014, PII S1550413107003713
-
Vujic Spasic M, et al. Hfe acts in hepatocytes to prevent hemochromatosis. Cell Metab. 2008; 7(2):173-178. (Pubitemid 351168556)
-
(2008)
Cell Metabolism
, vol.7
, Issue.2
, pp. 173-178
-
-
Vujic, S.M.1
Kiss, J.2
Herrmann, T.3
Galy, B.4
Martinache, S.5
Stolte, J.6
Grone, H.-J.7
Stremmel, W.8
Hentze, M.W.9
Muckenthaler, M.U.10
-
37
-
-
33646178285
-
A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)
-
Castoldi M, et al. A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). Rna. 2006;12(5):913-920.
-
(2006)
Rna
, vol.12
, Issue.5
, pp. 913-920
-
-
Castoldi, M.1
-
38
-
-
34548668636
-
MiChip: A microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes
-
DOI 10.1016/j.ymeth.2007.04.009, PII S1046202307000990
-
Castoldi M, Benes V, Hentze MW, Muckenthaler MU. miChip: A microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes. Methods. 2007;43(2):146-152. (Pubitemid 47419363)
-
(2007)
Methods
, vol.43
, Issue.2
, pp. 146-152
-
-
Castoldi, M.1
Benes, V.2
Hentze, M.W.3
Muckenthaler, M.U.4
-
39
-
-
39449096929
-
MiChip: An array-based method for microRNA expression profiling using locked nucleic acid capture probes
-
DOI 10.1038/nprot.2008.4, PII NPROT.2008.4
-
Castoldi M, Schmidt S, Benes V, Hentze MW, Muckenthaler MU. miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes. Nat Protoc. 2008;3(2):321-329. (Pubitemid 351266516)
-
(2008)
Nature Protocols
, vol.3
, Issue.2
, pp. 321-329
-
-
Castoldi, M.1
Schmidt, S.2
Benes, V.3
Hentze, M.W.4
Muckenthaler, M.U.5
-
40
-
-
67651250539
-
Enigma of primary aortoduodenal fistula
-
Bala M, Sosna J, Appelbaum L, Israeli E, Rivkind AI. Enigma of primary aortoduodenal fistula. World J Gastroenterol. 2009;15(25):3191-3193.
-
(2009)
World J Gastroenterol
, vol.15
, Issue.25
, pp. 3191-3193
-
-
Bala, M.1
Sosna, J.2
Appelbaum, L.3
Israeli, E.4
Rivkind, A.I.5
-
41
-
-
0034254752
-
The molecular defect in hypotransferrinemic mice
-
Trenor CC 3rd, Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice. Blood. 2000;96(3):1113-1118. (Pubitemid 30616881)
-
(2000)
Blood
, vol.96
, Issue.3
, pp. 1113-1118
-
-
Trenor III, C.C.1
Campagna, D.R.2
Sellers, V.M.3
Andrews, N.C.4
Fleming, M.D.5
-
42
-
-
33748997056
-
Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states
-
DOI 10.1111/j.1365-2257.2006.00812.x
-
Brugnara C, Schiller B, Moran J. Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states. Clin Lab Haematol. 2006; 28(5):303-308. (Pubitemid 44453675)
-
(2006)
Clinical and Laboratory Haematology
, vol.28
, Issue.5
, pp. 303-308
-
-
Brugnara, C.1
Schiller, B.2
Moran, J.3
-
43
-
-
0030801517
-
Molecular Probe Data Base (MPDB)
-
DOI 10.1093/nar/25.1.92
-
Campi MG, et al. Molecular Probe Data Base (MPDB). Nucleic Acids Res. 1997;25(1):92-95. (Pubitemid 27303156)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.1
, pp. 92-95
-
-
Campi, M.G.1
Castoldi, M.2
Romano, P.3
Thuroff, E.4
Manniello, M.A.5
Iannotta, B.6
Rondanina, G.7
Ruzzon, T.8
Santi, L.9
-
44
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
Babitt JL, et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38(5):531-539.
-
(2006)
Nat Genet
, vol.38
, Issue.5
, pp. 531-539
-
-
Babitt, J.L.1
-
45
-
-
70349494083
-
Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis
-
Corradini E, et al. Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis. Gastroenterology. 2009;137(4):1489-1497.
-
(2009)
Gastroenterology
, vol.137
, Issue.4
, pp. 1489-1497
-
-
Corradini, E.1
-
46
-
-
70350494274
-
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression
-
Kautz L, et al. BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression. Blood. 2009;114(12):2515-2520.
-
(2009)
Blood
, vol.114
, Issue.12
, pp. 2515-2520
-
-
Kautz, L.1
-
47
-
-
73149083742
-
Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload
-
Wallace DF, Summerville L, Crampton EM, Frazer DM, Anderson GJ, Subramaniam VN. Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. Hepatology. 2009;50(6):1992-2000.
-
(2009)
Hepatology
, vol.50
, Issue.6
, pp. 1992-2000
-
-
Wallace, D.F.1
Summerville, L.2
Crampton, E.M.3
Frazer, D.M.4
Anderson, G.J.5
Subramaniam, V.N.6
-
48
-
-
51649096725
-
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
-
Kautz L, et al. Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver. Blood. 2008;112(4):1503-1509.
-
(2008)
Blood
, vol.112
, Issue.4
, pp. 1503-1509
-
-
Kautz, L.1
-
49
-
-
14044251458
-
Human MicroRNA targets
-
John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Human MicroRNA targets. PLoS Biol. 2004;2(11):e363.
-
(2004)
PLoS Biol
, vol.2
, Issue.11
-
-
John, B.1
Enright, A.J.2
Aravin, A.3
Tuschl, T.4
Sander, C.5
Marks, D.S.6
-
50
-
-
20944450160
-
Combinatorial microRNA target predictions
-
DOI 10.1038/ng1536
-
Krek A, et al. Combinatorial microRNA target predictions. Nat Genet. 2005;37(5):495-500. (Pubitemid 40617277)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
MacMenamin, P.7
Da, P.I.8
Gunsalus, K.C.9
Stoffel, M.10
Rajewsky, N.11
-
51
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
Friedman JM, et al. The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res. 2009;69(6):2623-2629.
-
(2009)
Cancer Res
, vol.69
, Issue.6
, pp. 2623-2629
-
-
Friedman, J.M.1
-
52
-
-
33748587841
-
A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
-
DOI 10.1016/j.cell.2006.07.031, PII S0092867406010993
-
Miranda KC, et al. A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell. 2006;126(6):1203-1217. (Pubitemid 44380294)
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1203-1217
-
-
Miranda, K.C.1
Huynh, T.2
Tay, Y.3
Ang, Y.-S.4
Tam, W.-L.5
Thomson, A.M.6
Lim, B.7
Rigoutsos, I.8
-
53
-
-
42149179897
-
A GATA-1-regulated microRNA locus essential for erythropoiesis
-
DOI 10.1073/pnas.0712312105
-
Dore LC, et al. A GATA-1-regulated microRNA locus essential for erythropoiesis. Proc Natl Acad Sci U S A. 2008;105(9):3333-3338. (Pubitemid 351723553)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.9
, pp. 3333-3338
-
-
Dore, L.C.1
Amigo, J.D.2
Dos, S.C.O.3
Zhang, Z.4
Gai, X.5
Tobias, J.W.6
Yu, D.7
Klein, A.M.8
Dorman, C.9
Wu, W.10
Hardison, R.C.11
Paw, B.H.12
Weiss, M.J.13
-
54
-
-
61849183018
-
miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2
-
Pase L, Layton JE, Kloosterman WP, Carradice D, Waterhouse PM, Lieschke GJ. miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2. Blood. 2009;113(8):1794-1804.
-
(2009)
Blood
, vol.113
, Issue.8
, pp. 1794-1804
-
-
Pase, L.1
Layton, J.E.2
Kloosterman, W.P.3
Carradice, D.4
Waterhouse, P.M.5
Lieschke, G.J.6
-
55
-
-
77954408884
-
The miR-144/451 locus is required for erythroid homeostasis
-
Rasmussen KD, et al. The miR-144/451 locus is required for erythroid homeostasis. J Exp Med. 2010;207(7):1351-1358.
-
(2010)
J Exp Med
, vol.207
, Issue.7
, pp. 1351-1358
-
-
Rasmussen, K.D.1
-
56
-
-
33845985236
-
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
-
DOI 10.1182/blood-2006-07-033969
-
Verga Falzacappa MV, Vujic Spasic M, Kessler R, Stolte J, Hentze MW, Muckenthaler MU. STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. Blood. 2007;109(1):353-358. (Pubitemid 46053077)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 353-358
-
-
Verga, F.M.V.1
Spasic, M.V.2
Kessler, R.3
Stolte, J.4
Hentze, M.W.5
Muckenthaler, M.U.6
-
57
-
-
33751175421
-
Interleukin-6 induces hepcidin expression through STAT3
-
Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood. 2006;108(9):3204-3209.
-
(2006)
Blood
, vol.108
, Issue.9
, pp. 3204-3209
-
-
Wrighting, D.M.1
Andrews, N.C.2
-
58
-
-
56449096622
-
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
-
Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C. The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metab. 2008; 8(6):502-511.
-
(2008)
Cell Metab
, vol.8
, Issue.6
, pp. 502-511
-
-
Silvestri, L.1
Pagani, A.2
Nai, A.3
De Domenico, I.4
Kaplan, J.5
Camaschella, C.6
-
59
-
-
77950979752
-
SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
-
Mleczko-Sanecka K, et al. SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression. Blood. 2010;115(13):2657-2665.
-
(2010)
Blood
, vol.115
, Issue.13
, pp. 2657-2665
-
-
Mleczko-Sanecka, K.1
-
60
-
-
66149167562
-
Integration of microRNA miR- 122 in hepatic circadian gene expression
-
Gatfield D, et al. Integration of microRNA miR- 122 in hepatic circadian gene expression. Genes Dev. 2009;23(11):1313-1326.
-
(2009)
Genes Dev
, vol.23
, Issue.11
, pp. 1313-1326
-
-
Gatfield, D.1
-
61
-
-
77953713414
-
Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ ARE sequence motif at position -7007 of the FPN1 promoter
-
Marro S, et al. Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ ARE sequence motif at position -7007 of the FPN1 promoter. Haematologica. 2010;95(8):1261-1268.
-
(2010)
Haematologica
, vol.95
, Issue.8
, pp. 1261-1268
-
-
Marro, S.1
-
62
-
-
65249105959
-
Mechanisms controlling anaemia in Trypanosoma congolense infected mice
-
Noyes HA, et al. Mechanisms controlling anaemia in Trypanosoma congolense infected mice. PLoS One. 2009;4(4):e5170.
-
(2009)
PLoS One
, vol.4
, Issue.4
-
-
Noyes, H.A.1
-
63
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
DOI 10.1038/nature06783, PII NATURE06783
-
Elmen J, et al. LNA-mediated microRNA silencing in non-human primates. Nature. 2008; 452(7189):896-899. (Pubitemid 351550859)
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjarn, M.8
Hansen, H.F.9
Berger, U.10
Gullans, S.11
Kearney, P.12
Sarnow, P.13
Straarup, E.M.14
Kauppinen, S.15
-
64
-
-
74249112787
-
Therapeutic silencing of microRNA- 122 in primates with chronic hepatitis C virus infection
-
Lanford RE, et al. Therapeutic silencing of microRNA- 122 in primates with chronic hepatitis C virus infection. Science. 2010;327(5962):198-201.
-
(2010)
Science
, vol.327
, Issue.5962
, pp. 198-201
-
-
Lanford, R.E.1
-
65
-
-
34848878881
-
Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes
-
Shan Y, Zheng J, Lambrecht RW, Bonkovsky HL. Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes. Gastroenterology. 2007;133(4):1166-1174.
-
(2007)
Gastroenterology
, vol.133
, Issue.4
, pp. 1166-1174
-
-
Shan, Y.1
Zheng, J.2
Lambrecht, R.W.3
Bonkovsky, H.L.4
-
66
-
-
39649115776
-
The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression
-
DOI 10.1016/j.cmet.2007.11.016, PII S1550413107003737
-
Schmidt PJ, Toran PT, Giannetti AM, Bjorkman PJ, Andrews NC. The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. Cell Metab. 2008;7(3):205-214. (Pubitemid 351285524)
-
(2008)
Cell Metabolism
, vol.7
, Issue.3
, pp. 205-214
-
-
Schmidt, P.J.1
Toran, P.T.2
Giannetti, A.M.3
Bjorkman, P.J.4
Andrews, N.C.5
-
67
-
-
70349644493
-
Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum
-
Rodriguez A, Luukkaala T, Fleming RE, Britton RS, Bacon BR, Parkkila S. Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum. PLoS One. 2009;4(9):e7212.
-
(2009)
PLoS One
, vol.4
, Issue.9
-
-
Rodriguez, A.1
Luukkaala, T.2
Fleming, R.E.3
Britton, R.S.4
Bacon, B.R.5
Parkkila, S.6
-
68
-
-
0014267781
-
A simple technique for measuring storage iron concentrations in formalinised liver samples
-
Torrance JD, Bothwell TH. A simple technique for measuring storage iron concentrations in formalinised liver samples. S Afr J Med Sci. 1968;33(1):9-11.
-
(1968)
S Afr J Med Sci
, vol.33
, Issue.1
, pp. 9-11
-
-
Torrance, J.D.1
Bothwell, T.H.2
-
69
-
-
34248374866
-
Physiologic systemic iron metabolism in mice deficient for duodenal Hfe
-
Vujic Spasic M, et al. Physiologic systemic iron metabolism in mice deficient for duodenal Hfe. Blood. 2007;109(10):4511-4517.
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4511-4517
-
-
Vujic Spasic, M.1
-
70
-
-
45449087921
-
qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
-
Hellemans J, Mortier G, De Paepe A, Speleman F, Vandesompele J. qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol. 2007;8(2):R19.
-
(2007)
Genome Biol
, vol.8
, Issue.2
-
-
Hellemans, J.1
Mortier, G.2
De Paepe, A.3
Speleman, F.4
Vandesompele, J.5
-
71
-
-
0035710746
-
-DeltaDeltaCT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402-408. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
72
-
-
0037939676
-
Relationships and distinctions in iron-regulatory networks responding to interrelated signals
-
DOI 10.1182/blood-2002-07-2140
-
Muckenthaler M, et al. Relationships and distinctions in iron-regulatory networks responding to interrelated signals. Blood. 2003;101(9):3690-3698. (Pubitemid 36857961)
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3690-3698
-
-
Muckenthaler, M.1
Richter, A.2
Gunkel, N.3
Riedel, D.4
Polycarpou-Schwarz, M.5
Hentze, S.6
Falkenhahn, M.7
Stremmel, W.8
Ansorge, W.9
Hentze, M.W.10
-
73
-
-
33747884345
-
[19] Gene Expression Omnibus: Microarray Data Storage, Submission, Retrieval, and Analysis
-
DOI 10.1016/S0076-6879(06)11019-8, PII S0076687906110198, DNA Microarrays, Part B: Databases and Statistics
-
Barrett T, Edgar R. Gene expression omnibus: microarray data storage, submission, retrieval, and analysis. Methods Enzymol. 2006;411:352-369. (Pubitemid 44291435)
-
(2006)
Methods in Enzymology
, vol.411
, pp. 352-369
-
-
Barrett, T.1
Edgar, R.2
-
74
-
-
33750795440
-
Primary mouse hepatocytes for systems biology approaches: A standardized in vitro system for modelling of signal transduction pathways
-
DOI 10.1049/ip-syb:20050067
-
Klingmuller U, et al. Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways. Syst Biol (Stevenage). 2006;153(6):433-447. (Pubitemid 44712259)
-
(2006)
IEE Proceedings: Systems Biology
, vol.153
, Issue.6
, pp. 433-447
-
-
Klingmuller, U.1
Bauer, A.2
Bohl, S.3
Nickel, P.J.4
Breitkopf, K.5
Dooley, S.6
Zellmer, S.7
Kern, C.8
Merfort, I.9
Sparna, T.10
Donauer, J.11
Walz, G.12
Geyer, M.13
Kreutz, C.14
Hermes, M.15
Gotschel, F.16
Hecht, A.17
Walter, D.18
Egger, L.19
Neubert, K.20
Borner, C.21
Brulport, M.22
Schormann, W.23
Sauer, C.24
Baumann, F.25
Preiss, R.26
MacNelly, S.27
Godoy, P.28
Wiercinska, E.29
Ciuclan, L.30
Edelmann, J.31
Zeilinger, K.32
Heinrich, M.33
Zanger, U.M.34
Gebhardt, R.35
Maiwald, T.36
Heinrich, R.37
Timmer, J.38
Von, W.F.39
Hengstler, J.G.40
more..
|