-
1
-
-
0033038672
-
NAFLD: A spectrum of clinical and pathological severity
-
C.A. Matteoni, Z.M. Younossi, T. Gramlich, and et al. NAFLD: a spectrum of clinical and pathological severity Gastroenterology 116 1999 1413 1419
-
(1999)
Gastroenterology
, vol.116
, pp. 1413-1419
-
-
Matteoni, C.A.1
Younossi, Z.M.2
Gramlich, T.3
-
3
-
-
80555136061
-
Meta-analysis: Natural history of NAFLD and diagnostic accuracy of non-invasive tests for liver disease severity
-
G. Musso, R. Gambino, M. Cassader, and et al. Meta-analysis: natural history of NAFLD and diagnostic accuracy of non-invasive tests for liver disease severity Ann Med 43 2011 617 649
-
(2011)
Ann Med
, vol.43
, pp. 617-649
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
4
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human NASH
-
A.E. Feldstein, A. Canbay, P. Angulo, and et al. Hepatocyte apoptosis and fas expression are prominent features of human NASH Gastroenterology 125 2003 437 443
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
-
5
-
-
84859404868
-
Role of obesity and lipotoxicity in the development of NASH: Pathophysiology and clinical implications
-
e6
-
K. Cusi Role of obesity and lipotoxicity in the development of NASH: pathophysiology and clinical implications Gastroenterology 142 2012 711 725 e6
-
(2012)
Gastroenterology
, vol.142
, pp. 711-725
-
-
Cusi, K.1
-
7
-
-
20044374023
-
Design and validation of a histological scoring system for NAFLD
-
D.E. Kleiner, E.M. Brunt, M. Van Natta, and et al. Design and validation of a histological scoring system for NAFLD Hepatology 41 2005 1313 1321
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
-
9
-
-
36349024819
-
A lipidomic analysis of NAFLD
-
P. Puri, R.A. Baillie, M.M. Wiest, and et al. A lipidomic analysis of NAFLD Hepatology 46 2007 1081 1090
-
(2007)
Hepatology
, vol.46
, pp. 1081-1090
-
-
Puri, P.1
Baillie, R.A.2
Wiest, M.M.3
-
10
-
-
34250356015
-
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with NASH
-
K. Yamaguchi, L. Yang, S. McCall, and et al. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with NASH Hepatology 45 2007 1366 1374
-
(2007)
Hepatology
, vol.45
, pp. 1366-1374
-
-
Yamaguchi, K.1
Yang, L.2
McCall, S.3
-
11
-
-
84938057875
-
Liver fibrosis, but no other histologic features, associates with long-term outcomes of patients with NAFLD
-
P. Angulo, D.E. Kleiner, S. Dam-Larsen, and et al. Liver fibrosis, but no other histologic features, associates with long-term outcomes of patients with NAFLD Gastroenterology 149 2015 389 397
-
(2015)
Gastroenterology
, vol.149
, pp. 389-397
-
-
Angulo, P.1
Kleiner, D.E.2
Dam-Larsen, S.3
-
12
-
-
34447100647
-
Progressive fibrosis in NASH: Association with altered regeneration and a ductular reaction
-
M.M. Richardson, J.R. Jonsson, E.E. Powell, and et al. Progressive fibrosis in NASH: association with altered regeneration and a ductular reaction Gastroenterology 133 2007 80 90
-
(2007)
Gastroenterology
, vol.133
, pp. 80-90
-
-
Richardson, M.M.1
Jonsson, J.R.2
Powell, E.E.3
-
13
-
-
84939266502
-
NASH: Limited available treatment options but promising drugs in development and recent progress towards a regulatory approval pathway
-
C. Filozof, B.J. Goldstein, R.N. Williams, and et al. NASH: limited available treatment options but promising drugs in development and recent progress towards a regulatory approval pathway Drugs 75 2015 1373 1392
-
(2015)
Drugs
, vol.75
, pp. 1373-1392
-
-
Filozof, C.1
Goldstein, B.J.2
Williams, R.N.3
-
14
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with NAFLD
-
K.L. Donnelly, C.I. Smith, S.J. Schwarzenberg, and et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with NAFLD J Clin Invest 115 2005 1343 1351
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
-
15
-
-
84896414893
-
Adiposopathy, "sick fat," Ockham's razor, and resolution of the obesity paradox
-
H. Bays Adiposopathy, "sick fat," Ockham's razor, and resolution of the obesity paradox Curr Atheroscler Rep 16 2014 409
-
(2014)
Curr Atheroscler Rep
, vol.16
, pp. 409
-
-
Bays, H.1
-
16
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in NAFLD: Role of stearoyl-CoA desaturase
-
Z.Z. Li, M. Berk, T.M. McIntyre, and et al. Hepatic lipid partitioning and liver damage in NAFLD: role of stearoyl-CoA desaturase J Biol Chem 284 2009 5637 5644
-
(2009)
J Biol Chem
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
McIntyre, T.M.3
-
17
-
-
84884984539
-
Mitochondrial adaptations and dysfunctions in NAFLD
-
K. Begriche, J. Massart, M.A. Robin, and et al. Mitochondrial adaptations and dysfunctions in NAFLD Hepatology 58 2013 1497 1507
-
(2013)
Hepatology
, vol.58
, pp. 1497-1507
-
-
Begriche, K.1
Massart, J.2
Robin, M.A.3
-
18
-
-
0022007068
-
Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice
-
L.J. Brady, P.S. Brady, D.R. Romsos, and et al. Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice Biochem J 231 1985 439 444
-
(1985)
Biochem J
, vol.231
, pp. 439-444
-
-
Brady, L.J.1
Brady, P.S.2
Romsos, D.R.3
-
19
-
-
0033605261
-
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
-
K.D. Chavin, S. Yang, H.Z. Lin, and et al. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion J Biol Chem 274 1999 5692 5700
-
(1999)
J Biol Chem
, vol.274
, pp. 5692-5700
-
-
Chavin, K.D.1
Yang, S.2
Lin, H.Z.3
-
20
-
-
40749091283
-
Alterations of hepatic ATP homeostasis and respiratory chain during development of NASH in a rodent model
-
G. Serviddio, F. Bellanti, R. Tamborra, and et al. Alterations of hepatic ATP homeostasis and respiratory chain during development of NASH in a rodent model Eur J Clin Invest 38 2008 245 252
-
(2008)
Eur J Clin Invest
, vol.38
, pp. 245-252
-
-
Serviddio, G.1
Bellanti, F.2
Tamborra, R.3
-
21
-
-
0033520771
-
Alterations in liver ATP homeostasis in human NASH: A pilot study
-
H. Cortez-Pinto, J. Chatham, V.P. Chacko, and et al. Alterations in liver ATP homeostasis in human NASH: a pilot study JAMA 282 1999 1659 1664
-
(1999)
JAMA
, vol.282
, pp. 1659-1664
-
-
Cortez-Pinto, H.1
Chatham, J.2
Chacko, V.P.3
-
22
-
-
46349087273
-
Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of NASH liver to ischaemia-reperfusion injury
-
G. Serviddio, F. Bellanti, R. Tamborra, and et al. Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of NASH liver to ischaemia-reperfusion injury Gut 57 2008 957 965
-
(2008)
Gut
, vol.57
, pp. 957-965
-
-
Serviddio, G.1
Bellanti, F.2
Tamborra, R.3
-
23
-
-
84973121831
-
Programmed cell death and its role in inflammation
-
Y. Yang, G. Jiang, P. Zhang, and et al. Programmed cell death and its role in inflammation Mil Med Res 2 2015 12
-
(2015)
Mil Med Res
, vol.2
, pp. 12
-
-
Yang, Y.1
Jiang, G.2
Zhang, P.3
-
24
-
-
84937738375
-
Adaptation of hepatic mitochondrial function in humans with NAFL is lost in steatohepatitis
-
C. Koliaki, J. Szendroedi, K. Kaul, and et al. Adaptation of hepatic mitochondrial function in humans with NAFL is lost in steatohepatitis Cell Metab 21 2015 739 746
-
(2015)
Cell Metab
, vol.21
, pp. 739-746
-
-
Koliaki, C.1
Szendroedi, J.2
Kaul, K.3
-
25
-
-
84908430615
-
NAFLD: A main driver of insulin resistance or a dangerous liaison?
-
N. Gruben, R. Shiri-Sverdlov, D.P. Koonen, and et al. NAFLD: A main driver of insulin resistance or a dangerous liaison? Biochim Biophys Acta 1842 2014 2329 2343
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 2329-2343
-
-
Gruben, N.1
Shiri-Sverdlov, R.2
Koonen, D.P.3
-
26
-
-
84893051766
-
Insulin signaling, resistance, and the metabolic syndrome: Insights from mouse models into disease mechanisms
-
S. Guo Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms J Endocrinol 220 2014 T1 T23
-
(2014)
J Endocrinol
, vol.220
, pp. T1-T23
-
-
Guo, S.1
-
27
-
-
84863084237
-
FOXO1 involvement in insulin resistance-related pro-inflammatory cytokine production in hepatocytes
-
H. Miao, Y. Zhang, Z. Lu, and et al. FOXO1 involvement in insulin resistance-related pro-inflammatory cytokine production in hepatocytes Inflamm Res 61 2012 349 358
-
(2012)
Inflamm Res
, vol.61
, pp. 349-358
-
-
Miao, H.1
Zhang, Y.2
Lu, Z.3
-
28
-
-
0032994264
-
Insulin and insulin-like growth factor-1 stimulate proliferation and type i collagen accumulation by human hepatic stellate cells: Differential effects on signal transduction pathways
-
G. Svegliati-Baroni, F. Ridolfi, A. Di Sario, and et al. Insulin and insulin-like growth factor-1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: differential effects on signal transduction pathways Hepatology 29 1999 1743 1751
-
(1999)
Hepatology
, vol.29
, pp. 1743-1751
-
-
Svegliati-Baroni, G.1
Ridolfi, F.2
Di Sario, A.3
-
29
-
-
0036710140
-
Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids
-
G.B. Wisely, A.B. Miller, R.G. Davis, and et al. Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids Structure 10 2002 1225 1234
-
(2002)
Structure
, vol.10
, pp. 1225-1234
-
-
Wisely, G.B.1
Miller, A.B.2
Davis, R.G.3
-
30
-
-
84902657591
-
Role of gut microbiota and Toll-like receptors in NAFLD
-
K. Miura, and H. Ohnishi Role of gut microbiota and Toll-like receptors in NAFLD World J Gastroenterol 20 2014 7381 7391
-
(2014)
World J Gastroenterol
, vol.20
, pp. 7381-7391
-
-
Miura, K.1
Ohnishi, H.2
-
31
-
-
84946494125
-
Endoplasmic reticulum stress and oxidative stress in the pathogenesis of NAFLD
-
N.U. Ashraf, and T.A. Sheikh Endoplasmic reticulum stress and oxidative stress in the pathogenesis of NAFLD Free Radic Res 49 2015 1405 1418
-
(2015)
Free Radic Res
, vol.49
, pp. 1405-1418
-
-
Ashraf, N.U.1
Sheikh, T.A.2
-
34
-
-
84922424754
-
Dysregulation of iron and copper homeostasis in NAFL
-
E. Aigner, G. Weiss, and C. Datz Dysregulation of iron and copper homeostasis in NAFL World J Hepatol 7 2015 177 188
-
(2015)
World J Hepatol
, vol.7
, pp. 177-188
-
-
Aigner, E.1
Weiss, G.2
Datz, C.3
-
35
-
-
60549103890
-
Iron overload is associated with hepatic oxidative damage to DNA in NASH
-
N. Fujita, H. Miyachi, H. Tanaka, and et al. Iron overload is associated with hepatic oxidative damage to DNA in NASH Cancer Epidemiol Biomarkers Prev 18 2009 424 432
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 424-432
-
-
Fujita, N.1
Miyachi, H.2
Tanaka, H.3
-
36
-
-
34247171870
-
Normal iron metabolism and the pathophysiology of iron overload disorders
-
C.W. Siah, J. Ombiga, L.A. Adams, and et al. Normal iron metabolism and the pathophysiology of iron overload disorders Clin Biochem Rev 27 2006 5 16
-
(2006)
Clin Biochem Rev
, vol.27
, pp. 5-16
-
-
Siah, C.W.1
Ombiga, J.2
Adams, L.A.3
-
37
-
-
11144356355
-
Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in NASH
-
C. Namikawa, Z. Shu-Ping, J.R. Vyselaar, and et al. Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in NASH J Hepatol 40 2004 781 786
-
(2004)
J Hepatol
, vol.40
, pp. 781-786
-
-
Namikawa, C.1
Shu-Ping, Z.2
Vyselaar, J.R.3
-
38
-
-
84929313688
-
Fibrosis in NAFLD: Mechanisms and clinical implications
-
P. Angulo, M.V. Machado, and A.M. Diehl Fibrosis in NAFLD: mechanisms and clinical implications Semin Liver Dis 35 2015 132 145
-
(2015)
Semin Liver Dis
, vol.35
, pp. 132-145
-
-
Angulo, P.1
MacHado, M.V.2
Diehl, A.M.3
-
39
-
-
84893143662
-
Liver renewal: Detecting misrepair and optimizing regeneration
-
M.V. Machado, and A.M. Diehl Liver renewal: detecting misrepair and optimizing regeneration Mayo Clin Proc 89 2014 120 130
-
(2014)
Mayo Clin Proc
, vol.89
, pp. 120-130
-
-
MacHado, M.V.1
Diehl, A.M.2
-
41
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
J. Henao-Mejia, E. Elinav, C. Jin, and et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity Nature 482 2012 179 185
-
(2012)
Nature
, vol.482
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
-
42
-
-
84929841362
-
Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage
-
C. Mogler, M. Wieland, C. Konig, and et al. Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage EMBO Mol Med 7 2015 332 338
-
(2015)
EMBO Mol Med
, vol.7
, pp. 332-338
-
-
Mogler, C.1
Wieland, M.2
Konig, C.3
-
43
-
-
84892370936
-
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
-
B.S. Ding, Z. Cao, R. Lis, and et al. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis Nature 505 2014 97 102
-
(2014)
Nature
, vol.505
, pp. 97-102
-
-
Ding, B.S.1
Cao, Z.2
Lis, R.3
-
44
-
-
84946725758
-
Identifying novel targets for treatment of liver fibrosis: What can we learn from injured tissues which heal without a scar?
-
M.T. Pritchard, and J.M. McCracken Identifying novel targets for treatment of liver fibrosis: what can we learn from injured tissues which heal without a scar? Curr Drug Targets 16 2015 1332 1346
-
(2015)
Curr Drug Targets
, vol.16
, pp. 1332-1346
-
-
Pritchard, M.T.1
McCracken, J.M.2
-
45
-
-
77950350763
-
Expression of perilipin and adipophilin in NAFLD; Relevance to oxidative injury and hepatocyte ballooning
-
H. Fujii, Y. Ikura, J. Arimoto, and et al. Expression of perilipin and adipophilin in NAFLD; relevance to oxidative injury and hepatocyte ballooning J Atheroscler Thromb 16 2009 893 901
-
(2009)
J Atheroscler Thromb
, vol.16
, pp. 893-901
-
-
Fujii, H.1
Ikura, Y.2
Arimoto, J.3
-
46
-
-
84933039083
-
Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with NASH
-
M.V. Machado, G.A. Michelotti, T.D. Pereira, and et al. Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with NASH Gut 64 2015 1148 1157
-
(2015)
Gut
, vol.64
, pp. 1148-1157
-
-
MacHado, M.V.1
Michelotti, G.A.2
Pereira, T.D.3
-
47
-
-
79958229659
-
Increased production of sonic hedgehog by ballooned hepatocytes
-
F. Rangwala, C.D. Guy, J. Lu, and et al. Increased production of sonic hedgehog by ballooned hepatocytes J Pathol 224 2011 401 410
-
(2011)
J Pathol
, vol.224
, pp. 401-410
-
-
Rangwala, F.1
Guy, C.D.2
Lu, J.3
-
48
-
-
80055043169
-
Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of NAFLD in mice
-
L. Li, L. Chen, L. Hu, and et al. Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of NAFLD in mice Hepatology 54 2011 1620 1630
-
(2011)
Hepatology
, vol.54
, pp. 1620-1630
-
-
Li, L.1
Chen, L.2
Hu, L.3
-
49
-
-
84861573996
-
Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human NAFLD
-
C.D. Guy, A. Suzuki, M. Zdanowicz, and et al. Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human NAFLD Hepatology 55 2012 1711 1721
-
(2012)
Hepatology
, vol.55
, pp. 1711-1721
-
-
Guy, C.D.1
Suzuki, A.2
Zdanowicz, M.3
-
50
-
-
59849085125
-
Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells
-
e2
-
R.P. Witek, L. Yang, R. Liu, and et al. Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells Gastroenterology 136 2009 320 330 e2
-
(2009)
Gastroenterology
, vol.136
, pp. 320-330
-
-
Witek, R.P.1
Yang, L.2
Liu, R.3
-
51
-
-
84956620363
-
Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease
-
D. Povero, A. Eguchi, H. Li, and et al. Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease PLoS One 9 2014 e113651
-
(2014)
PLoS One
, vol.9
, pp. e113651
-
-
Povero, D.1
Eguchi, A.2
Li, H.3
-
52
-
-
84958835221
-
Alcohol stimulates macrophage activation through caspase dependent hepatocyte derived release of CD40L containing extracellular vesicles
-
V.K. Verma, H. Li, R. Wang, and et al. Alcohol stimulates macrophage activation through caspase dependent hepatocyte derived release of CD40L containing extracellular vesicles J Hepatol 64 2016 651 660
-
(2016)
J Hepatol
, vol.64
, pp. 651-660
-
-
Verma, V.K.1
Li, H.2
Wang, R.3
-
53
-
-
84961844659
-
Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate
-
H. Nojima, C.M. Freeman, R.M. Schuster, and et al. Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate J Hepatol 64 2016 60 68
-
(2016)
J Hepatol
, vol.64
, pp. 60-68
-
-
Nojima, H.1
Freeman, C.M.2
Schuster, R.M.3
-
54
-
-
84951754288
-
Exosome adherence and internalization by hepatic stellate cells triggers sphingosine 1-phosphate dependent migration
-
R. Wang, Q. Ding, U. Yaqoob, and et al. Exosome adherence and internalization by hepatic stellate cells triggers sphingosine 1-phosphate dependent migration J Biol Chem 290 2015 30684 30696
-
(2015)
J Biol Chem
, vol.290
, pp. 30684-30696
-
-
Wang, R.1
Ding, Q.2
Yaqoob, U.3
-
55
-
-
84904060793
-
Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy
-
M. Swiderska-Syn, W.K. Syn, G. Xie, and et al. Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy Gut 63 2014 1333 1344
-
(2014)
Gut
, vol.63
, pp. 1333-1344
-
-
Swiderska-Syn, M.1
Syn, W.K.2
Xie, G.3
-
56
-
-
78651426961
-
The role of Hedgehog signaling in fibrogenic liver repair
-
S.S. Choi, A. Omenetti, W.K. Syn, and et al. The role of Hedgehog signaling in fibrogenic liver repair Int J Biochem Cell Biol 43 2011 238 244
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 238-244
-
-
Choi, S.S.1
Omenetti, A.2
Syn, W.K.3
-
57
-
-
42049104913
-
The adventures of Shh in development and repair. III. Hedgehog processing and biological activity
-
S.F. Farzan, S. Singh, N.S. Schilling, and et al. The adventures of Shh in development and repair. III. Hedgehog processing and biological activity Am J Physiol Gastrointest Liver Physiol 294 2008 G844 G849
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
, pp. G844-G849
-
-
Farzan, S.F.1
Singh, S.2
Schilling, N.S.3
-
58
-
-
84879414522
-
The mechanisms of Hedgehog signalling and its roles in development and disease
-
J. Briscoe, and P.P. Therond The mechanisms of Hedgehog signalling and its roles in development and disease Nat Rev Mol Cell Biol 14 2013 416 429
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 416-429
-
-
Briscoe, J.1
Therond, P.P.2
-
59
-
-
77954949822
-
Role of lipid metabolism in smoothened derepression in hedgehog signaling
-
A. Yavari, R. Nagaraj, E. Owusu-Ansah, and et al. Role of lipid metabolism in smoothened derepression in hedgehog signaling Dev Cell 19 2010 54 65
-
(2010)
Dev Cell
, vol.19
, pp. 54-65
-
-
Yavari, A.1
Nagaraj, R.2
Owusu-Ansah, E.3
-
60
-
-
84856098531
-
Oxysterols are allosteric activators of the oncoprotein Smoothened
-
S. Nachtergaele, L.K. Mydock, K. Krishnan, and et al. Oxysterols are allosteric activators of the oncoprotein Smoothened Nat Chem Biol 8 2012 211 220
-
(2012)
Nat Chem Biol
, vol.8
, pp. 211-220
-
-
Nachtergaele, S.1
Mydock, L.K.2
Krishnan, K.3
-
61
-
-
77951722845
-
Signals from dying hepatocytes trigger growth of liver progenitors
-
Y. Jung, R.P. Witek, W.K. Syn, and et al. Signals from dying hepatocytes trigger growth of liver progenitors Gut 59 2010 655 665
-
(2010)
Gut
, vol.59
, pp. 655-665
-
-
Jung, Y.1
Witek, R.P.2
Syn, W.K.3
-
62
-
-
84875452685
-
Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals
-
W. Palm, M.M. Swierczynska, V. Kumari, and et al. Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals PLoS Biol 11 2013 e1001505
-
(2013)
PLoS Biol
, vol.11
, pp. e1001505
-
-
Palm, W.1
Swierczynska, M.M.2
Kumari, V.3
-
63
-
-
84901462346
-
The role of glypicans in Hedgehog signaling
-
J. Filmus, and M. Capurro The role of glypicans in Hedgehog signaling Matrix Biol 35 2014 248 252
-
(2014)
Matrix Biol
, vol.35
, pp. 248-252
-
-
Filmus, J.1
Capurro, M.2
-
64
-
-
84878527104
-
Smoothened is a master regulator of adult liver repair
-
G.A. Michelotti, G. Xie, M. Swiderska, and et al. Smoothened is a master regulator of adult liver repair J Clin Invest 123 2013 2380 2394
-
(2013)
J Clin Invest
, vol.123
, pp. 2380-2394
-
-
Michelotti, G.A.1
Xie, G.2
Swiderska, M.3
-
65
-
-
84872093661
-
Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation
-
G. Xie, S.S. Choi, W.K. Syn, and et al. Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation Gut 62 2013 299 309
-
(2013)
Gut
, vol.62
, pp. 299-309
-
-
Xie, G.1
Choi, S.S.2
Syn, W.K.3
-
66
-
-
84865041500
-
NKT-associated hedgehog and osteopontin drive fibrogenesis in NAFLD
-
W.K. Syn, K.M. Agboola, M. Swiderska, and et al. NKT-associated hedgehog and osteopontin drive fibrogenesis in NAFLD Gut 61 2012 1323 1329
-
(2012)
Gut
, vol.61
, pp. 1323-1329
-
-
Syn, W.K.1
Agboola, K.M.2
Swiderska, M.3
-
67
-
-
84870825988
-
Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni
-
T.A. Pereira, G. Xie, S.S. Choi, and et al. Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni Liver Int 33 2013 149 161
-
(2013)
Liver Int
, vol.33
, pp. 149-161
-
-
Pereira, T.A.1
Xie, G.2
Choi, S.S.3
-
68
-
-
33645823699
-
Hedgehog signaling maintains resident hepatic progenitors throughout life
-
J.K. Sicklick, Y.X. Li, A. Melhem, and et al. Hedgehog signaling maintains resident hepatic progenitors throughout life Am J Physiol Gastrointest Liver Physiol 290 2006 G859 G870
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, pp. G859-G870
-
-
Sicklick, J.K.1
Li, Y.X.2
Melhem, A.3
-
69
-
-
72749094687
-
Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis
-
S.S. Choi, A. Omenetti, R.P. Witek, and et al. Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis Am J Physiol Gastrointest Liver Physiol 297 2009 G1093 G1106
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, pp. G1093-G1106
-
-
Choi, S.S.1
Omenetti, A.2
Witek, R.P.3
-
70
-
-
84887015586
-
Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice
-
G. Xie, G. Karaca, M. Swiderska-Syn, and et al. Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice Hepatology 58 2013 1801 1813
-
(2013)
Hepatology
, vol.58
, pp. 1801-1813
-
-
Xie, G.1
Karaca, G.2
Swiderska-Syn, M.3
-
71
-
-
68949194359
-
Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production
-
A. Omenetti, W.K. Syn, Y. Jung, and et al. Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production Hepatology 50 2009 518 527
-
(2009)
Hepatology
, vol.50
, pp. 518-527
-
-
Omenetti, A.1
Syn, W.K.2
Jung, Y.3
-
72
-
-
84893092076
-
Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe NAFLD
-
C.A. Moylan, H. Pang, A. Dellinger, and et al. Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe NAFLD Hepatology 59 2014 471 482
-
(2014)
Hepatology
, vol.59
, pp. 471-482
-
-
Moylan, C.A.1
Pang, H.2
Dellinger, A.3
-
73
-
-
84885027595
-
Role of the Hedgehog pathway in hepatocellular carcinoma
-
X. Zheng, W. Zeng, X. Gai, and et al. Role of the Hedgehog pathway in hepatocellular carcinoma Oncol Rep 30 2013 2020 2026
-
(2013)
Oncol Rep
, vol.30
, pp. 2020-2026
-
-
Zheng, X.1
Zeng, W.2
Gai, X.3
-
74
-
-
84877092655
-
The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma
-
L. Tang, Y.X. Tan, B.G. Jiang, and et al. The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma Clin Cancer Res 19 2013 2014 2024
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2014-2024
-
-
Tang, L.1
Tan, Y.X.2
Jiang, B.G.3
-
75
-
-
84941935061
-
Accumulation of duct cells with activated YAP parallels fibrosis progression in NAFLD
-
M.V. Machado, G.A. Michelotti, A. Pereira Tde, and et al. Accumulation of duct cells with activated YAP parallels fibrosis progression in NAFLD J Hepatol 63 2015 962 970
-
(2015)
J Hepatol
, vol.63
, pp. 962-970
-
-
MacHado, M.V.1
Michelotti, G.A.2
Pereira Tde, A.3
-
76
-
-
84920984254
-
Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity
-
C.D. Guy, A. Suzuki, M.F. Abdelmalek, and et al. Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity Hepatology 61 2015 98 107
-
(2015)
Hepatology
, vol.61
, pp. 98-107
-
-
Guy, C.D.1
Suzuki, A.2
Abdelmalek, M.F.3
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