Macrophage-derived hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni

Liver International

Volumn 33, Issue 1, 2013, Pages 149-161

  Pereira, Thiago A ^a,b   Xie, Guanhua ^a   Choi, Steve S ^a,c   Syn, Wing Kin ^a,d   Voieta, Izabela ^e   Lu, Jiuyi ^a   Chan, Isaac S ^a   Swiderska, Marzena ^a   Amaral, Kirsten B ^f   Antunes, Carlos M ^e   Secor, William E ^f   Witek, Rafal P ^g   Lambertucci, José R ^e   Pereira, Fausto L ^h   Diehl, Anna Mae ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c DURHAM VA MEDICAL CENTER   (United States)

^d INSTITUTE OF HEPATOLOGY   (United Kingdom)

^e FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^f CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^g Life Technologies   (United States)

^h FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

Author keywords

Alternative activation of macrophages; Fibrosis; Hedgehog pathway; Schistosomiasis mansoni; Vascular remodelling

Indexed keywords

ANTIGEN; MESSENGER RNA; SCHISTOSOME EGG ANTIGEN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANGIOGENESIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIUM CELL; FEMALE; FIBROGENESIS; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER BIOPSY; LIVER FIBROSIS; LIVER INJURY; MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE MIGRATION; MALE; MYOFIBROBLAST; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHISTOSOMIASIS; SCHISTOSOMIASIS MANSONI; ULTRASOUND; UPREGULATION;

ADULT; ANIMALS; BIOPSY; CELL LINE; ENDOTHELIAL CELLS; FEMALE; GENES, REPORTER; HEDGEHOG PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; KUPFFER CELLS; LIGANDS; LIVER; LIVER CIRRHOSIS; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MIDDLE AGED; MYOFIBROBLASTS; NEOVASCULARIZATION, PATHOLOGIC; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; TRANSFECTION; YOUNG ADULT;

EID: 84870825988     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12016     Document Type: Article

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