Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Povero, Davide ^a   Eguchi, Akiko ^a   Li, Hongying ^b   Johnson, Casey D ^a   Papouchado, Bettina G ^c   Wree, Alexander ^a   Messer, Karen ^b   Feldstein, Ariel E ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; AMINO ACID DERIVATIVE; ASIALOGLYCOPROTEIN RECEPTOR; BIOLOGICAL MARKER; CALCEIN; CARBOXYLESTERASE; CD31 ANTIGEN; CD63 ANTIGEN; CD81 ANTIGEN; CHOLINE DEFICIENT AMINO ACID; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6 RECEPTOR; LIPOCORTIN 5; MICRORNA 122; MICRORNA 192; PROTEOME; TRANSFORMING GROWTH FACTOR; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN A; MICRORNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MONITORING; BLOOD ANALYSIS; CELL DEATH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIET RESTRICTION; DIETARY INTAKE; DISEASE COURSE; DISEASE MARKER; EXOSOME; EXTRACELLULAR VESICLE; FLUORESCENCE ACTIVATED CELL SORTING; GENE LOCATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIPID DIET; LIVER; LIVER CELL DAMAGE; LIVER FIBROSIS; LIVER INJURY; LIVER LEVEL; MALE; MEMBRANE MICROPARTICLE; MEMBRANE VESICLE; MOUSE; MOUSE MODEL; NEOVASCULARIZATION (PATHOLOGY); NONALCOHOLIC FATTY LIVER; NONHUMAN; OBSERVATIONAL STUDY; PATHOPHYSIOLOGY; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; RNA ANALYSIS; RNA ISOLATION; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; UPREGULATION; ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; VITAMIN DEFICIENCY;

ANIMALS; BIOMARKERS; CELL-DERIVED MICROPARTICLES; CHOLINE DEFICIENCY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; EXOSOMES; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; NON-ALCOHOLIC FATTY LIVER DISEASE; PROTEOME;

EID: 84956620363     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113651     Document Type: Article

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