Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate

Journal of Hepatology

Volumn 64, Issue 1, 2016, Pages 60-68

  Nojima, Hiroyuki ^a   Freeman, Christopher M ^a   Schuster, Rebecca M ^a   Japtok, Lukasz ^b   Kleuser, Burkhard ^b   Edwards, Michael J ^a   Gulbins, Erich ^a,c   Lentsch, Alex B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF POTSDAM   (Germany)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Ischemia reperfusion; Liver injury; Sphingolipids; Sphingosine kinase; Transplantation

Indexed keywords

CD63 ANTIGEN; CD81 ANTIGEN; EARLY ENDOSOME ANTIGEN 1; GLUCOSE REGULATED PROTEIN 78; NEUTRAL CERAMIDASE; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE; SPHINGOSINE KINASE 2; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE 2, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELL PROLIFERATION; CELL SHAPE; CELL SIZE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; EXOSOME; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER INJURY; LIVER ISCHEMIA; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; PHYSIOLOGY;

ANIMALS; CELL PROLIFERATION; EXOSOMES; HEPATOCYTES; LIVER REGENERATION; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, INBRED C57BL; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SPHINGOSINE;

EID: 84961844659     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.07.030     Document Type: Article

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