Rescue of glaucomatous neurodegeneration by differentially modulating neuronal endoplasmic reticulum stress molecules

Journal of Neuroscience

Volumn 36, Issue 21, 2016, Pages 5891-5903

  Yang, Liu ^a   Li, Shaohua ^a,c   Miao, Linqing ^a   Huang, Haoliang ^a   Liang, Feisi ^a   Teng, Xiuyin ^a   Xu, Lin ^a,d   Wang, Qizhao ^b   Xiao, Weidong ^b   Ridder, William H ^e   Ferguson, Toby A ^f   Chen, Dong Feng ^g   Kaufman, Randal J ^h   Hu, Yang ^a,b  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d QINGDAO UNIVERSITY   (China)

^e SOUTHERN CALIFORNIA COLLEGE OF OPTOMETRY   (United States)

^f BIOGEN   (United States)

^g SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^h BURNHAM INSTITUTE   (United States)

Author keywords

Axon degeneration; ER stress; Glaucoma; Neuroprotection; Optic nerve; Retinal ganglion cell

Indexed keywords

HEAT SHOCK PROTEIN; INITIATION FACTOR 2; NERVE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONAL INJURY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE TARGETING; GLAUCOMA; GLAUCOMATOUS OPTIC NEUROPATHY; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL NECROSIS; NERVE FIBER DEGENERATION; NEUROPROTECTION; NONHUMAN; OPTIC NERVE INJURY; PHOSPHORYLATION; PRIORITY JOURNAL; RETINA GANGLION CELL; VISUAL CORTEX; VISUAL EVOKED POTENTIAL; VISUAL SYSTEM FUNCTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DEGENERATIVE DISEASE; FEMALE; MALE; METABOLISM; RETINA DEGENERATION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; ENDOPLASMIC RETICULUM STRESS; FEMALE; GLAUCOMA; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; RETINAL DEGENERATION; RETINAL GANGLION CELLS; UNFOLDED PROTEIN RESPONSE;

EID: 84969849520     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3709-15.2016     Document Type: Article

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