Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 10, 2013, Pages 4045-4050

  Welsbie, Derek S ^a,b   Yang, Zhiyong ^a   Ge, Yan ^a,c   Mitchell, Katherine L ^a   Zhou, Xinrong ^a,d   Martin, Scott E ^e   Berlinicke, Cynthia A ^a   Hackler, Laszlo ^a   Fuller, John ^a   Fu, Jie ^a,b   Cao, Li Hui ^a   Han, Bing ^a,b   Auld, Douglas ^e   Xue, Tian ^a   Hirai, Syu Ichi ^f   Germain, Lucie ^g,h   Simard Bisson, Caroline ^g,h   Blouin, Richard ⁱ   Nguyen, Judy V ^a   Davis, Chung Ha O ^j   Enke, Raymond A ^a   Boye, Sanford L ^k   Merbs, Shannath L ^a   Marsh Armstrong, Nicholas ^a,j   Hauswirth, William W ^k   Diantonio, Aaron ^l   Nickells, Robert W ^m   Inglese, James ^e,n   Hanes, Justin ^a,b   Yau, King Wai ^a   Quigley, Harry A ^a,b   Zack, Donald J ^a,b,o   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^d HARBIN MEDICAL UNIVERSITY   (China)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^g LAVAL UNIVERSITY   (Canada)

^h UNIVERSITÉ LAVAL   (Canada)

ⁱ UNIVERSITÉ DE SHERBROOKE   (Canada)

^j KENNEDY KRIEGER INSTITUTE   (United States)

^k UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^l WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m UNIVERSITY OF WISCONSIN MADISON   (United States)

ⁿ NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^o INSTITUT DE LA VISION   (France)

more..

Author keywords

Drug discovery; MAP3K12; Neuroprotection

Indexed keywords

AXITINIB; CRIZOTINIB; FORETINIB; IMATINIB; LESTAURTINIB; LEUCINE ZIPPER KINASE; NEUROPROTECTIVE AGENT; PROTEIN KINASE; RNA; SMALL INTERFERING RNA; SORAFENIB; TANDUTINIB; TOZASERTIB; UNCLASSIFIED DRUG; VANDETANIB; VATALANIB; [4 [2 (1H INDAZOL 3 YL)VINYL]PHENYL](1 PIPERAZINYL)METHANONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AXONAL INJURY; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; GENE DELIVERY SYSTEM; GENE TARGETING; GLAUCOMA; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; MALE; MEDIATOR; MOUSE; NONHUMAN; OPTIC NERVE DISEASE; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; RECEPTOR UPREGULATION; RETINA GANGLION CELL; RNA INTERFERENCE; RODENT; SIGNAL TRANSDUCTION;

EID: 84874629422     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211284110     Document Type: Article

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