-
1
-
-
19944431275
-
A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses
-
Adalbert, R., T.H. Gillingwater, J.E. Haley, K. Bridge, B. Beirowski, L. Berek, D. Wagner, D. Grumme, D. Thomson, A. Celik, et al. 2005. A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses. Eur. J. Neurosci. 21:271-277. http://dx.doi.org/10.1111/j.1460-9568.2004.03833.x
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 271-277
-
-
Adalbert, R.1
Gillingwater, T.H.2
Haley, J.E.3
Bridge, K.4
Beirowski, B.5
Berek, L.6
Wagner, D.7
Grumme, D.8
Thomson, D.9
Celik, A.10
-
2
-
-
77649133016
-
NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death
-
Alano, C.C., P. Garnier, W. Ying, Y. Higashi, T.M. Kauppinen, and R.A. Swanson. 2010. NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J. Neurosci. 30:2967-2978. http://dx.doi.org/10.1523/JNEUROSCI.5552-09.2010
-
(2010)
J. Neurosci.
, vol.30
, pp. 2967-2978
-
-
Alano, C.C.1
Garnier, P.2
Ying, W.3
Higashi, Y.4
Kauppinen, T.M.5
Swanson, R.A.6
-
3
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki, T., Y. Sasaki, and J. Milbrandt. 2004. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science. 305: 1010-1013. http://dx.doi.org/10.1126/science.1098014
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
4
-
-
61449233205
-
Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration
-
Avery, M.A., A.E. Sheehan, K.S. Kerr, J. Wang, and M.R. Freeman. 2009. Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration. J. Cell Biol. 184:501-513. http://dx.doi.org/10.1083/jcb.200808042
-
(2009)
J. Cell Biol.
, vol.184
, pp. 501-513
-
-
Avery, M.A.1
Sheehan, A.E.2
Kerr, K.S.3
Wang, J.4
Freeman, M.R.5
-
5
-
-
77957740998
-
Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo
-
Babetto, E., B. Beirowski, L. Janeckova, R. Brown, J. Gilley, D. Thomson, R.R. Ribchester, and M.P. Coleman. 2010. Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo. J. Neurosci. 30:13291-13304. http://dx.doi.org/10.1523/JNEUROSCI.1189-10.2010
-
(2010)
J. Neurosci.
, vol.30
, pp. 13291-13304
-
-
Babetto, E.1
Beirowski, B.2
Janeckova, L.3
Brown, R.4
Gilley, J.5
Thomson, D.6
Ribchester, R.R.7
Coleman, M.P.8
-
6
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines, C.P., R.A. Kaiser, N.H. Purcell, N.S. Blair, H. Osinska, M.A. Hambleton, E.W. Brunskill, M.R. Sayen, R.A. Gottlieb, G.W. Dorn, et al. 2005. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature. 434:658-662. http://dx.doi.org/10.1038/nature03434
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn, G.W.10
-
7
-
-
78751565419
-
Axonal degeneration is mediated by the mitochondrial permeability transition pore
-
Barrientos, S.A., N.W. Martinez, S. Yoo, J.S. Jara, S. Zamorano, C. Hetz, J.L. Twiss, J. Alvarez, and F.A. Court. 2011. Axonal degeneration is mediated by the mitochondrial permeability transition pore. J. Neurosci. 31:966-978. http://dx.doi.org/10.1523/JNEUROSCI.4065-10.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 966-978
-
-
Barrientos, S.A.1
Martinez, N.W.2
Yoo, S.3
Jara, J.S.4
Zamorano, S.5
Hetz, C.6
Twiss, J.L.7
Alvarez, J.8
Court, F.A.9
-
8
-
-
1242328756
-
Quantitative and qualitative analysis of Wallerian degeneration using restricted axonal labelling in YFPH mice
-
Beirowski, B., L. Berek, R. Adalbert, D. Wagner, D.S. Grumme, K. Addicks, R.R. Ribchester, and M.P. Coleman. 2004. Quantitative and qualitative analysis of Wallerian degeneration using restricted axonal labelling in YFPH mice. J. Neurosci. Methods. 134:23-35. http://dx.doi.org/10.1016/j.jneumeth.2003.10.016
-
(2004)
J. Neurosci. Methods.
, vol.134
, pp. 23-35
-
-
Beirowski, B.1
Berek, L.2
Adalbert, R.3
Wagner, D.4
Grumme, D.S.5
Addicks, K.6
Ribchester, R.R.7
Coleman, M.P.8
-
9
-
-
24344506747
-
The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves
-
Beirowski, B., R. Adalbert, D. Wagner, D.S. Grumme, K. Addicks, R.R. Ribchester, and M.P. Coleman. 2005. The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves. BMC Neurosci. 6:6. http://dx.doi.org/10.1186/1471-2202-6-6
-
(2005)
BMC Neurosci
, vol.6
, pp. 6
-
-
Beirowski, B.1
Adalbert, R.2
Wagner, D.3
Grumme, D.S.4
Addicks, K.5
Ribchester, R.R.6
Coleman, M.P.7
-
10
-
-
58849126602
-
Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo
-
Beirowski, B., E. Babetto, J. Gilley, F. Mazzola, L. Conforti, L. Janeckova, G. Magni, R.R. Ribchester, and M.P. Coleman. 2009. Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo. J. Neurosci. 29:653-668. http://dx.doi.org/10.1523/JNEUROSCI.3814-08.2009
-
(2009)
J. Neurosci.
, vol.29
, pp. 653-668
-
-
Beirowski, B.1
Babetto, E.2
Gilley, J.3
Mazzola, F.4
Conforti, L.5
Janeckova, L.6
Magni, G.7
Ribchester, R.R.8
Coleman, M.P.9
-
11
-
-
27744501798
-
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
-
Berger, F., C. Lau, M. Dahlmann, and M. Ziegler. 2005. Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J. Biol. Chem. 280:36334-36341. http://dx.doi.org/10.1074/jbc.M508660200
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36334-36341
-
-
Berger, F.1
Lau, C.2
Dahlmann, M.3
Ziegler, M.4
-
12
-
-
0023931244
-
Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules
-
Billger, M., M. Wallin, and J.O. Karlsson. 1988. Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules. Cell Calcium. 9:33-44. http://dx.doi.org/10.1016/0143-4160(88)90036-X
-
(1988)
Cell Calcium
, vol.9
, pp. 33-44
-
-
Billger, M.1
Wallin, M.2
Karlsson, J.O.3
-
13
-
-
0345379310
-
Postinjury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury
-
Büki, A., D.O. Okonkwo, and J.T. Povlishock. 1999. Postinjury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury. J. Neurotrauma. 16:511-521. http://dx.doi.org/10.1089/neu.1999.16.511
-
(1999)
J. Neurotrauma.
, vol.16
, pp. 511-521
-
-
Büki, A.1
Okonkwo, D.O.2
Povlishock, J.T.3
-
14
-
-
38149129457
-
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function
-
Cahoy, J.D., B. Emery, A. Kaushal, L.C. Foo, J.L. Zamanian, K.S. Christopherson, Y. Xing, J.L. Lubischer, P.A. Krieg, S.A. Krupenko, et al. 2008. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J. Neurosci. 28:264-278. http://dx.doi.org/10.1523/JNEUROSCI.4178-07.2008
-
(2008)
J. Neurosci.
, vol.28
, pp. 264-278
-
-
Cahoy, J.D.1
Emery, B.2
Kaushal, A.3
Foo, L.C.4
Zamanian, J.L.5
Christopherson, K.S.6
Xing, Y.7
Lubischer, J.L.8
Krieg, P.A.9
Krupenko, S.A.10
-
15
-
-
0000494564
-
The significance of the "dying back" process in experimental and human neurological disease
-
Cavanagh, J.B. 1964. The significance of the "dying back" process in experimental and human neurological disease. Int. Rev. Exp. Pathol. 3:219-267.
-
(1964)
Int. Rev. Exp. Pathol.
, vol.3
, pp. 219-267
-
-
Cavanagh, J.B.1
-
16
-
-
79951531959
-
Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy
-
Cheng, H.C., S.R. Kim, T.F. Oo, T. Kareva, O. Yarygina, M. Rzhetskaya, C. Wang, M. During, Z. Talloczy, K. Tanaka, et al. 2011. Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy. J. Neurosci. 31:2125-2135. http://dx.doi.org/10.1523/JNEUROSCI.5519-10.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 2125-2135
-
-
Cheng, H.C.1
Kim, S.R.2
Oo, T.F.3
Kareva, T.4
Yarygina, O.5
Rzhetskaya, M.6
Wang, C.7
During, M.8
Talloczy, Z.9
Tanaka, K.10
-
17
-
-
27644591304
-
Axon degeneration mechanisms: commonality amid diversity
-
Coleman, M. 2005. Axon degeneration mechanisms: commonality amid diversity. Nat. Rev. Neurosci. 6:889-898. http://dx.doi.org/10.1038/nrn1788
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 889-898
-
-
Coleman, M.1
-
18
-
-
77957001346
-
Wallerian degeneration, wld(s), and nmnat
-
Coleman, M.P., and M.R. Freeman. 2010. Wallerian degeneration, wld(s), and nmnat. Annu. Rev. Neurosci. 33:245-267. http://dx.doi.org/10.1146/annurevneuro-060909-153248
-
(2010)
Annu. Rev. Neurosci.
, vol.33
, pp. 245-267
-
-
Coleman, M.P.1
Freeman, M.R.2
-
19
-
-
0034633627
-
A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse
-
Conforti, L., A. Tarlton, T.G. Mack, W. Mi, E.A. Buckmaster, D. Wagner, V.H. Perry, and M.P. Coleman. 2000. A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse. Proc. Natl. Acad. Sci. USA. 97:11377-11382. http://dx.doi.org/10.1073/pnas.97.21.11377
-
(2000)
Proc. Natl. Acad. Sci. USA.
, vol.97
, pp. 11377-11382
-
-
Conforti, L.1
Tarlton, A.2
Mack, T.G.3
Mi, W.4
Buckmaster, E.A.5
Wagner, D.6
Perry, V.H.7
Coleman, M.P.8
-
20
-
-
61449113031
-
Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice
-
Conforti, L., A. Wilbrey, G. Morreale, L. Janeckova, B. Beirowski, R. Adalbert, F. Mazzola, M. Di Stefano, R. Hartley, E. Babetto, et al. 2009. Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice. J. Cell Biol. 184:491-500. http://dx.doi.org/10.1083/jcb.200807175
-
(2009)
J. Cell Biol.
, vol.184
, pp. 491-500
-
-
Conforti, L.1
Wilbrey, A.2
Morreale, G.3
Janeckova, L.4
Beirowski, B.5
Adalbert, R.6
Mazzola, F.7
Di Stefano, M.8
Hartley, R.9
Babetto, E.10
-
21
-
-
0027956623
-
Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis)
-
Deckwerth, T.L., and E.M. Johnson Jr. 1994. Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis). Dev. Biol. 165:63-72. http://dx.doi.org/10.1006/dbio.1994.1234
-
(1994)
Dev. Biol.
, vol.165
, pp. 63-72
-
-
Deckwerth, T.L.1
Johnson Jr., E.M.2
-
22
-
-
0032101320
-
Endocytotic formation of vesicles and other membranous structures induced by Ca2+ and axolemmal injury
-
Eddleman, C.S., M.L. Ballinger, M.E. Smyers, H.M. Fishman, and G.D. Bittner. 1998. Endocytotic formation of vesicles and other membranous structures induced by Ca2+ and axolemmal injury. J. Neurosci. 18:4029-4041.
-
(1998)
J. Neurosci.
, vol.18
, pp. 4029-4041
-
-
Eddleman, C.S.1
Ballinger, M.L.2
Smyers, M.E.3
Fishman, H.M.4
Bittner, G.D.5
-
23
-
-
0019171269
-
Microtrabecular structure of the axoplasmic matrix: visualization of cross-linking structures and their distribution
-
Ellisman, M.H., and K.R. Porter. 1980. Microtrabecular structure of the axoplasmic matrix: visualization of cross-linking structures and their distribution. J. Cell Biol. 87:464-479. http://dx.doi.org/10.1083/jcb.87.2.464
-
(1980)
J. Cell Biol.
, vol.87
, pp. 464-479
-
-
Ellisman, M.H.1
Porter, K.R.2
-
24
-
-
0344950387
-
Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease
-
Ferri, A., J.R. Sanes, M.P. Coleman, J.M. Cunningham, and A.C. Kato. 2003. Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease. Curr. Biol. 13:669-673. http://dx.doi.org/10.1016/S0960-9822(03)00206-9
-
(2003)
Curr. Biol.
, vol.13
, pp. 669-673
-
-
Ferri, A.1
Sanes, J.R.2
Coleman, M.P.3
Cunningham, J.M.4
Kato, A.C.5
-
25
-
-
0034652278
-
Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases
-
Finn, J.T., M. Weil, F. Archer, R. Siman, A. Srinivasan, and M.C. Raff. 2000. Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases. J. Neurosci. 20:1333-1341.
-
(2000)
J. Neurosci.
, vol.20
, pp. 1333-1341
-
-
Finn, J.T.1
Weil, M.2
Archer, F.3
Siman, R.4
Srinivasan, A.5
Raff, M.C.6
-
26
-
-
1542489512
-
The relationship of body size, nerve cell size, axon length, and glial density in the cerebellum
-
Friede, R.L. 1963. The relationship of body size, nerve cell size, axon length, and glial density in the cerebellum. Proc. Natl. Acad. Sci. USA. 49:187-193. http://dx.doi.org/10.1073/pnas.49.2.187
-
(1963)
Proc. Natl. Acad. Sci. USA.
, vol.49
, pp. 187-193
-
-
Friede, R.L.1
-
27
-
-
0028793887
-
Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels
-
George, E.B., J.D. Glass, and J.W. Griffin. 1995. Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels. J. Neurosci. 15:6445-6452.
-
(1995)
J. Neurosci.
, vol.15
, pp. 6445-6452
-
-
George, E.B.1
Glass, J.D.2
Griffin, J.W.3
-
28
-
-
0027970246
-
Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model
-
George, R., and J.W. Griffin. 1994. Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model. Exp. Neurol. 129:225-236. http://dx.doi.org/10.1006/exnr.1994.1164
-
(1994)
Exp. Neurol.
, vol.129
, pp. 225-236
-
-
George, R.1
Griffin, J.W.2
-
29
-
-
80051519518
-
Image-based screening identifies novel roles for IKK and GSK3 in axonal degeneration
-
Gerdts, J., Y. Sasaki, B. Vohra, J. Marasa, and J. Milbrandt. 2011. Image-based screening identifies novel roles for IKK and GSK3 in axonal degeneration. J. Biol. Chem. 286:28011-28018. http://dx.doi.org/10.1074/jbc.M111.250472
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28011-28018
-
-
Gerdts, J.1
Sasaki, Y.2
Vohra, B.3
Marasa, J.4
Milbrandt, J.5
-
30
-
-
77954617977
-
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons
-
Gilley, J., and M.P. Coleman. 2010. Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons. PLoS Biol. 8:e1000300. http://dx.doi.org/10.1371/journal.pbio.1000300
-
(2010)
PLoS Biol
, vol.8
-
-
Gilley, J.1
Coleman, M.P.2
-
31
-
-
33745058436
-
Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion
-
Gillingwater, T.H., C.A. Ingham, K.E. Parry, A.K. Wright, J.E. Haley, T.M. Wishart, G.W. Arbuthnott, and R.R. Ribchester. 2006a. Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion. Brain. 129:1546-1556. http://dx.doi.org/10.1093/brain/awl101
-
(2006)
Brain
, vol.129
, pp. 1546-1556
-
-
Gillingwater, T.H.1
Ingham, C.A.2
Parry, K.E.3
Wright, A.K.4
Haley, J.E.5
Wishart, T.M.6
Arbuthnott, G.W.7
Ribchester, R.R.8
-
32
-
-
32144434891
-
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells
-
Gillingwater, T.H., T.M. Wishart, P.E. Chen, J.E. Haley, K. Robertson, S.H. MacDonald, S. Middleton, K. Wawrowski, M.J. Shipston, S. Melmed, et al. 2006b. The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Hum. Mol. Genet. 15:625-635. http://dx.doi.org/10.1093/hmg/ddi478
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 625-635
-
-
Gillingwater, T.H.1
Wishart, T.M.2
Chen, P.E.3
Haley, J.E.4
Robertson, K.5
MacDonald, S.H.6
Middleton, S.7
Wawrowski, K.8
Shipston, M.J.9
Melmed, S.10
-
33
-
-
0027225572
-
Prolonged survival of transected nerve fibres in C57BL/Ola mice is an intrinsic characteristic of the axon
-
Glass, J.D., T.M. Brushart, E.B. George, and J.W. Griffin. 1993. Prolonged survival of transected nerve fibres in C57BL/Ola mice is an intrinsic characteristic of the axon. J. Neurocytol. 22:311-321. http://dx.doi.org/10.1007/BF01195555
-
(1993)
J. Neurocytol.
, vol.22
, pp. 311-321
-
-
Glass, J.D.1
Brushart, T.M.2
George, E.B.3
Griffin, J.W.4
-
34
-
-
0028286279
-
Calcium-mediated degeneration of the axonal cytoskeleton in the Ola mouse
-
Glass, J.D., B.L. Schryer, and J.W. Griffin. 1994. Calcium-mediated degeneration of the axonal cytoskeleton in the Ola mouse. J. Neurochem. 62:2472-2475. http://dx.doi.org/10.1046/j.1471-4159.1994.62062472.x
-
(1994)
J. Neurochem.
, vol.62
, pp. 2472-2475
-
-
Glass, J.D.1
Schryer, B.L.2
Griffin, J.W.3
-
35
-
-
0037090434
-
Very early activation of m-calpain in peripheral nerve during Wallerian degeneration
-
Glass, J.D., D.G. Culver, A.I. Levey, and N.R. Nash. 2002. Very early activation of m-calpain in peripheral nerve during Wallerian degeneration. J. Neurol. Sci. 196:9-20. http://dx.doi.org/10.1016/S0022-510X(02)00013-8
-
(2002)
J. Neurol. Sci.
, vol.196
, pp. 9-20
-
-
Glass, J.D.1
Culver, D.G.2
Levey, A.I.3
Nash, N.R.4
-
36
-
-
0002367881
-
Axonal degeneration and disorders of the axonal cytoskeleton
-
S.G. Waxman, J. D. Kocsis, P. K. Sytys, editors. Oxford University Press, NY
-
Griffin, J.W., E.B. George, S.T. Hsiesh, and J.D. Glass. 1995. Axonal degeneration and disorders of the axonal cytoskeleton. In The Axon: Structure, Function and Pathophysiology. S.G. Waxman, J.D. Kocsis, P.K. Sytys, editors. Oxford University Press, NY. 3750-3790.
-
(1995)
The Axon: Structure, Function and Pathophysiology
, pp. 3750-3790
-
-
Griffin, J.W.1
George, E.B.2
Hsiesh, S.T.3
Glass, J.D.4
-
37
-
-
0018254261
-
Endoplasmic reticulum sequesters calcium in the squid giant axon
-
Henkart, M.P., T.S. Reese, and F.J. Brinley Jr. 1978. Endoplasmic reticulum sequesters calcium in the squid giant axon. Science. 202:1300-1303. http://dx.doi.org/10.1126/science.725607
-
(1978)
Science
, vol.202
, pp. 1300-1303
-
-
Henkart, M.P.1
Reese, T.S.2
Brinley Jr., F.J.3
-
38
-
-
33744922406
-
Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning
-
Hoopfer, E.D., T. McLaughlin, R.J. Watts, O. Schuldiner, D.D. O'Leary, and L. Luo. 2006. Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning. Neuron. 50:883-895. http://dx.doi.org/10.1016/j.neuron.2006.05.013
-
(2006)
Neuron
, vol.50
, pp. 883-895
-
-
Hoopfer, E.D.1
McLaughlin, T.2
Watts, R.J.3
Schuldiner, O.4
O'Leary, D.D.5
Luo, L.6
-
39
-
-
38049075806
-
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma
-
Howell, G.R., R.T. Libby, T.C. Jakobs, R.S. Smith, F.C. Phalan, J.W. Barter, J.M. Barbay, J.K. Marchant, N. Mahesh, V. Porciatti, et al. 2007. Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma. J. Cell Biol. 179:1523-1537. http://dx.doi.org/10.1083/jcb.200706181
-
(2007)
J. Cell Biol.
, vol.179
, pp. 1523-1537
-
-
Howell, G.R.1
Libby, R.T.2
Jakobs, T.C.3
Smith, R.S.4
Phalan, F.C.5
Barter, J.W.6
Barbay, J.M.7
Marchant, J.K.8
Mahesh, N.9
Porciatti, V.10
-
40
-
-
33846406104
-
Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axonprotective function
-
Jia, H., T. Yan, Y. Feng, C. Zeng, X. Shi, and Q. Zhai. 2007. Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axonprotective function. Neurosci. Lett. 413:46-51. http://dx.doi.org/10.1016/j.neulet.2006.11.067
-
(2007)
Neurosci. Lett.
, vol.413
, pp. 46-51
-
-
Jia, H.1
Yan, T.2
Feng, Y.3
Zeng, C.4
Shi, X.5
Zhai, Q.6
-
41
-
-
0025731595
-
Degradation of microtubuleassociated protein 2 and brain spectrin by calpain: a comparative study
-
Johnson, G.V., J.M. Litersky, and R.S. Jope. 1991. Degradation of microtubuleassociated protein 2 and brain spectrin by calpain: a comparative study. J. Neurochem. 56:1630-1638. http://dx.doi.org/10.1111/j.1471-4159.1991.tb02061.x
-
(1991)
J. Neurochem.
, vol.56
, pp. 1630-1638
-
-
Johnson, G.V.1
Litersky, J.M.2
Jope, R.S.3
-
42
-
-
0029788777
-
mu-calpain activation and calpain-mediated cytoskeletal proteolysis following traumatic brain injury
-
Kampfl, A., R. Posmantur, R. Nixon, F. Grynspan, X. Zhao, S.J. Liu, J.K. Newcomb, G.L. Clifton, and R.L. Hayes. 1996. mu-calpain activation and calpain-mediated cytoskeletal proteolysis following traumatic brain injury. J. Neurochem. 67:1575-1583. http://dx.doi.org/10.1046/j.1471-4159.1996.67041575.x
-
(1996)
J. Neurochem.
, vol.67
, pp. 1575-1583
-
-
Kampfl, A.1
Posmantur, R.2
Nixon, R.3
Grynspan, F.4
Zhao, X.5
Liu, S.J.6
Newcomb, J.K.7
Clifton, G.L.8
Hayes, R.L.9
-
43
-
-
33748908067
-
Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models
-
Kaneko, S., J. Wang, M. Kaneko, G. Yiu, J.M. Hurrell, T. Chitnis, S.J. Khoury, and Z. He. 2006. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J. Neurosci. 26:9794-9804. http://dx.doi.org/10.1523/JNEUROSCI.2116-06.2006
-
(2006)
J. Neurosci.
, vol.26
, pp. 9794-9804
-
-
Kaneko, S.1
Wang, J.2
Kaneko, M.3
Yiu, G.4
Hurrell, J.M.5
Chitnis, T.6
Khoury, S.J.7
He, Z.8
-
44
-
-
18844436224
-
In vivo imaging of axonal degeneration and regeneration in the injured spinal cord
-
Kerschensteiner, M., M.E. Schwab, J.W. Lichtman, and T. Misgeld. 2005. In vivo imaging of axonal degeneration and regeneration in the injured spinal cord. Nat. Med. 11:572-577. http://dx.doi.org/10.1038/nm1229
-
(2005)
Nat. Med.
, vol.11
, pp. 572-577
-
-
Kerschensteiner, M.1
Schwab, M.E.2
Lichtman, J.W.3
Misgeld, T.4
-
45
-
-
1642540210
-
The mitochondrial calcium uniporter is a highly selective ion channel
-
Kirichok, Y., G. Krapivinsky, and D.E. Clapham. 2004. The mitochondrial calcium uniporter is a highly selective ion channel. Nature. 427:360-364. http://dx.doi.org/10.1038/nature02246
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Clapham, D.E.3
-
46
-
-
77950534568
-
Mechanisms of acute axonal degeneration in the optic nerve in vivo
-
Knöferle, J., J.C. Koch, T. Ostendorf, U. Michel, V. Planchamp, P. Vutova, L. Tönges, C. Stadelmann, W. Brück, M. Bähr, and P. Lingor. 2010. Mechanisms of acute axonal degeneration in the optic nerve in vivo. Proc. Natl. Acad. Sci. USA. 107:6064-6069. http://dx.doi.org/10.1073/pnas.0909794107
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 6064-6069
-
-
Knöferle, J.1
Koch, J.C.2
Ostendorf, T.3
Michel, U.4
Planchamp, V.5
Vutova, P.6
Tönges, L.7
Stadelmann, C.8
Brück, W.9
Bähr, M.10
Lingor, P.11
-
47
-
-
33644850360
-
The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus
-
Laser, H., L. Conforti, G. Morreale, T.G. Mack, M. Heyer, J.E. Haley, T.M. Wishart, B. Beirowski, S.A. Walker, G. Haase, et al. 2006. The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Mol. Biol. Cell. 17:1075-1084. http://dx.doi.org/10.1091/mbc.E05-04-0375
-
(2006)
Mol. Biol. Cell.
, vol.17
, pp. 1075-1084
-
-
Laser, H.1
Conforti, L.2
Morreale, G.3
Mack, T.G.4
Heyer, M.5
Haley, J.E.6
Wishart, T.M.7
Beirowski, B.8
Walker, S.A.9
Haase, G.10
-
48
-
-
0022401384
-
The neuronal endomembrane system. III. The origins of the axoplasmic reticulum and discrete axonal cisternae at the axon hillock
-
Lindsey, J.D., and M.H. Ellisman. 1985. The neuronal endomembrane system. III. The origins of the axoplasmic reticulum and discrete axonal cisternae at the axon hillock. J. Neurosci. 5:3135-3144.
-
(1985)
J. Neurosci.
, vol.5
, pp. 3135-3144
-
-
Lindsey, J.D.1
Ellisman, M.H.2
-
49
-
-
0025191894
-
Effects of axotomy on distribution and concentration of elements in rat sciatic nerve
-
LoPachin, R.M. Jr., V.R. LoPachin, and A.J. Saubermann. 1990. Effects of axotomy on distribution and concentration of elements in rat sciatic nerve. J. Neurochem. 54:320-332. http://dx.doi.org/10.1111/j.1471-4159.1990.tb13317.x
-
(1990)
J. Neurochem.
, vol.54
, pp. 320-332
-
-
LoPachin Jr., R.M.1
LoPachin, V.R.2
Saubermann, A.J.3
-
50
-
-
25844511803
-
A little nip and tuck: axon refinement during development and axonal injury
-
Low, L.K., and H.J. Cheng. 2005. A little nip and tuck: axon refinement during development and axonal injury. Curr. Opin. Neurobiol. 15:549-556. http://dx.doi.org/10.1016/j.conb.2005.08.007
-
(2005)
Curr. Opin. Neurobiol.
, vol.15
, pp. 549-556
-
-
Low, L.K.1
Cheng, H.J.2
-
51
-
-
0017656426
-
Early course of Wallerian degeneration in myelinated fibres of the rat phrenic nerve
-
Lubińska, L. 1977. Early course of Wallerian degeneration in myelinated fibres of the rat phrenic nerve. Brain Res. 130:47-63. http://dx.doi.org/10.1016/0006-8993(77)90841-1
-
(1977)
Brain Res
, vol.130
, pp. 47-63
-
-
Lubińska, L.1
-
52
-
-
0020026030
-
Patterns of Wallerian degeneration of myelinated fibres in short and long peripheral stumps and in isolated segments of rat phrenic nerve. Interpretation of the role of axoplasmic flow of the trophic factor
-
Lubińska, L. 1982. Patterns of Wallerian degeneration of myelinated fibres in short and long peripheral stumps and in isolated segments of rat phrenic nerve. Interpretation of the role of axoplasmic flow of the trophic factor. Brain Res. 233:227-240. http://dx.doi.org/10.1016/0006-8993(82)91199-4
-
(1982)
Brain Res
, vol.233
, pp. 227-240
-
-
Lubińska, L.1
-
53
-
-
0026748618
-
Delayed wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study
-
Ludwin, S.K., and M.A. Bisby. 1992. Delayed wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study. J. Neurol. Sci. 109:140-147. http://dx.doi.org/10.1016/0022-510X(92)90160-M
-
(1992)
J. Neurol. Sci.
, vol.109
, pp. 140-147
-
-
Ludwin, S.K.1
Bisby, M.A.2
-
54
-
-
0024373441
-
Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve
-
Lunn, E.R., V.H. Perry, M.C. Brown, H. Rosen, and S. Gordon. 1989. Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve. Eur. J. Neurosci. 1:27-33. http://dx.doi.org/10.1111/j.1460-9568.1989.tb00771.x
-
(1989)
Eur. J. Neurosci.
, vol.1
, pp. 27-33
-
-
Lunn, E.R.1
Perry, V.H.2
Brown, M.C.3
Rosen, H.4
Gordon, S.5
-
55
-
-
23244436227
-
Axon retraction and degeneration in development and disease
-
Luo, L., and D.D. O'Leary. 2005. Axon retraction and degeneration in development and disease. Annu. Rev. Neurosci. 28:127-156. http://dx.doi.org/10.1146/annurev.neuro.28.061604.135632
-
(2005)
Annu. Rev. Neurosci.
, vol.28
, pp. 127-156
-
-
Luo, L.1
O'Leary, D.D.2
-
56
-
-
33744926927
-
The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons
-
MacDonald, J.M., M.G. Beach, E. Porpiglia, A.E. Sheehan, R.J. Watts, and M.R. Freeman. 2006. The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron. 50:869-881. http://dx.doi.org/10.1016/j.neuron.2006.04.028
-
(2006)
Neuron
, vol.50
, pp. 869-881
-
-
MacDonald, J.M.1
Beach, M.G.2
Porpiglia, E.3
Sheehan, A.E.4
Watts, R.J.5
Freeman, M.R.6
-
57
-
-
14644415960
-
Regulation of Wallerian degeneration and nerve growth factor withdrawal-induced pruning of axons of sympathetic neurons by the proteasome and the MEK/Erk pathway
-
MacInnis, B.L., and R.B. Campenot. 2005. Regulation of Wallerian degeneration and nerve growth factor withdrawal-induced pruning of axons of sympathetic neurons by the proteasome and the MEK/Erk pathway. Mol. Cell. Neurosci. 28:430-439. http://dx.doi.org/10.1016/j.mcn.2004.10.003
-
(2005)
Mol. Cell. Neurosci.
, vol.28
, pp. 430-439
-
-
MacInnis, B.L.1
Campenot, R.B.2
-
58
-
-
0035195636
-
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene
-
Mack, T.G., M. Reiner, B. Beirowski, W. Mi, M. Emanuelli, D. Wagner, D. Thomson, T. Gillingwater, F. Court, L. Conforti, et al. 2001. Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat. Neurosci. 4:1199-1206. http://dx.doi.org/10.1038/nn770
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 1199-1206
-
-
Mack, T.G.1
Reiner, M.2
Beirowski, B.3
Mi, W.4
Emanuelli, M.5
Wagner, D.6
Thomson, D.7
Gillingwater, T.8
Court, F.9
Conforti, L.10
-
59
-
-
0036842251
-
A missense mutation in Tbce causes progressive motor neuronopathy in mice
-
Martin, N., J. Jaubert, P. Gounon, E. Salido, G. Haase, M. Szatanik, and J.L. Guénet. 2002. A missense mutation in Tbce causes progressive motor neuronopathy in mice. Nat. Genet. 32:443-447. http://dx.doi.org/10.1038/ng1016
-
(2002)
Nat. Genet.
, vol.32
, pp. 443-447
-
-
Martin, N.1
Jaubert, J.2
Gounon, P.3
Salido, E.4
Haase, G.5
Szatanik, M.6
Guénet, J.L.7
-
60
-
-
59049099831
-
A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins
-
Merianda, T.T., A.C. Lin, J.S. Lam, D. Vuppalanchi, D.E. Willis, N. Karin, C.E. Holt, and J.L. Twiss. 2009. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol. Cell. Neurosci. 40:128-142. http://dx.doi.org/10.1016/j.mcn.2008.09.008
-
(2009)
Mol. Cell. Neurosci.
, vol.40
, pp. 128-142
-
-
Merianda, T.T.1
Lin, A.C.2
Lam, J.S.3
Vuppalanchi, D.4
Willis, D.E.5
Karin, N.6
Holt, C.E.7
Twiss, J.L.8
-
61
-
-
79751528889
-
The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration
-
Meyer zu Horste, G., T.A. Miesbach, J.I. Muller, R. Fledrich, R.M. Stassart, B.C. Kieseier, M.P. Coleman, and M.W. Sereda. 2011. The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration. Neurobiol. Dis. 42:1-8. http://dx.doi.org/10.1016/j.nbd.2010.12.006
-
(2011)
Neurobiol. Dis
, vol.42
, pp. 1-8
-
-
Meyer Zu Horste, G.1
Miesbach, T.A.2
Muller, J.I.3
Fledrich, R.4
Stassart, R.M.5
Kieseier, B.C.6
Coleman, M.P.7
Sereda, M.W.8
-
62
-
-
63649153518
-
A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration
-
Miller, B.R., C. Press, R.W. Daniels, Y. Sasaki, J. Milbrandt, and A. DiAntonio. 2009. A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration. Nat. Neurosci. 12:387-389. http://dx.doi.org/10.1038/nn.2290
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 387-389
-
-
Miller, B.R.1
Press, C.2
Daniels, R.W.3
Sasaki, Y.4
Milbrandt, J.5
DiAntonio, A.6
-
63
-
-
60149101523
-
Motor axon excitability during Wallerian degeneration
-
Moldovan, M., S. Alvarez, and C. Krarup. 2009. Motor axon excitability during Wallerian degeneration. Brain. 132:511-523. http://dx.doi.org/10.1093/brain/awn332
-
(2009)
Brain
, vol.132
, pp. 511-523
-
-
Moldovan, M.1
Alvarez, S.2
Krarup, C.3
-
64
-
-
60549089207
-
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
-
Nikolaev, A., T. McLaughlin, D.D. O'Leary, and M. Tessier-Lavigne. 2009. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature. 457:981-989. http://dx.doi.org/10.1038/nature07767
-
(2009)
Nature
, vol.457
, pp. 981-989
-
-
Nikolaev, A.1
McLaughlin, T.2
O'Leary, D.D.3
Tessier-Lavigne, M.4
-
65
-
-
27344452894
-
Na+-dependent sources of intra-axonal Ca2+ release in rat optic nerve during in vitro chemical ischemia
-
Nikolaeva, M.A., B. Mukherjee, and P.K. Stys. 2005. Na+-dependent sources of intra-axonal Ca2+ release in rat optic nerve during in vitro chemical ischemia. J. Neurosci. 25:9960-9967. http://dx.doi.org/10.1523/JNEUROSCI.2003-05.2005
-
(2005)
J. Neurosci.
, vol.25
, pp. 9960-9967
-
-
Nikolaeva, M.A.1
Mukherjee, B.2
Stys, P.K.3
-
66
-
-
0141750468
-
Depolarizationinduced Ca2+ release in ischemic spinal cord white matter involves L-type Ca2+ channel activation of ryanodine receptors
-
Ouardouz, M., M.A. Nikolaeva, E. Coderre, G.W. Zamponi, J.E. McRory, B.D. Trapp, X. Yin, W. Wang, J. Woulfe, and P.K. Stys. 2003. Depolarizationinduced Ca2+ release in ischemic spinal cord white matter involves L-type Ca2+ channel activation of ryanodine receptors. Neuron. 40:53-63. http://dx.doi.org/10.1016/j.neuron.2003.08.016
-
(2003)
Neuron
, vol.40
, pp. 53-63
-
-
Ouardouz, M.1
Nikolaeva, M.A.2
Coderre, E.3
Zamponi, G.W.4
McRory, J.E.5
Trapp, B.D.6
Yin, X.7
Wang, W.8
Woulfe, J.9
Stys, P.K.10
-
67
-
-
77956928316
-
MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake
-
Perocchi, F., V.M. Gohil, H.S. Girgis, X.R. Bao, J.E. McCombs, A.E. Palmer, and V.K. Mootha. 2010. MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature. 467:291-296. http://dx.doi.org/10.1038/nature09358
-
(2010)
Nature
, vol.467
, pp. 291-296
-
-
Perocchi, F.1
Gohil, V.M.2
Girgis, H.S.3
Bao, X.R.4
McCombs, J.E.5
Palmer, A.E.6
Mootha, V.K.7
-
68
-
-
0025974211
-
Very slow retrograde and Wallerian degeneration in the CNS of C57BL/Ola mice
-
Perry, V.H., M.C. Brown, and E.R. Lunn. 1991. Very slow retrograde and Wallerian degeneration in the CNS of C57BL/Ola mice. Eur. J. Neurosci. 3:102-105. http://dx.doi.org/10.1111/j.1460-9568.1991.tb00815.x
-
(1991)
Eur. J. Neurosci.
, vol.3
, pp. 102-105
-
-
Perry, V.H.1
Brown, M.C.2
Lunn, E.R.3
-
69
-
-
44949233176
-
Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress
-
Press, C., and J. Milbrandt. 2008. Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. J. Neurosci. 28:4861-4871. http://dx.doi.org/10.1523/JNEUROSCI.0525-08.2008
-
(2008)
J. Neurosci.
, vol.28
, pp. 4861-4871
-
-
Press, C.1
Milbrandt, J.2
-
70
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff, M.C., A.V. Whitmore, and J.T. Finn. 2002. Axonal self-destruction and neurodegeneration. Science. 296:868-871. http://dx.doi.org/10.1126/science.1068613
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
71
-
-
34247549679
-
The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis
-
Rasola, A., and P. Bernardi. 2007. The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis. Apoptosis. 12:815-833. http://dx.doi.org/10.1007/s10495-007-0723-y
-
(2007)
Apoptosis
, vol.12
, pp. 815-833
-
-
Rasola, A.1
Bernardi, P.2
-
72
-
-
68249154947
-
Axotomy depletes intracellular calcium stores in primary sensory neurons
-
Rigaud, M., G. Gemes, P.D. Weyker, J.M. Cruikshank, T. Kawano, H.E. Wu, and Q.H. Hogan. 2009. Axotomy depletes intracellular calcium stores in primary sensory neurons. Anesthesiology. 111:381-392. http://dx.doi.org/10.1097/ALN.0b013e3181ae6212
-
(2009)
Anesthesiology
, vol.111
, pp. 381-392
-
-
Rigaud, M.1
Gemes, G.2
Weyker, P.D.3
Cruikshank, J.M.4
Kawano, T.5
Wu, H.E.6
Hogan, Q.H.7
-
73
-
-
0032511112
-
Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses
-
Rizzuto, R., P. Pinton, W. Carrington, F.S. Fay, K.E. Fogarty, L.M. Lifshitz, R.A. Tuft, and T. Pozzan. 1998. Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Science. 280:1763-1766. http://dx.doi.org/10.1126/science.280.5370.1763
-
(1998)
Science
, vol.280
, pp. 1763-1766
-
-
Rizzuto, R.1
Pinton, P.2
Carrington, W.3
Fay, F.S.4
Fogarty, K.E.5
Lifshitz, L.M.6
Tuft, R.A.7
Pozzan, T.8
-
74
-
-
0028865136
-
Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease
-
Sagot, Y., M. Dubois-Dauphin, S.A. Tan, F. de Bilbao, P. Aebischer, J.C. Martinou, and A.C. Kato. 1995. Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease. J. Neurosci. 15:7727-7733.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7727-7733
-
-
Sagot, Y.1
Dubois-Dauphin, M.2
Tan, S.A.3
de Bilbao, F.4
Aebischer, P.5
Martinou, J.C.6
Kato, A.C.7
-
75
-
-
0037388411
-
The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy
-
Samsam, M., W. Mi, C. Wessig, J. Zielasek, K.V. Toyka, M.P. Coleman, and R. Martini. 2003. The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy. J. Neurosci. 23:2833-2839.
-
(2003)
J. Neurosci
, vol.23
, pp. 2833-2839
-
-
Samsam, M.1
Mi, W.2
Wessig, C.3
Zielasek, J.4
Toyka, K.V.5
Coleman, M.P.6
Martini, R.7
-
76
-
-
78650647681
-
Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons
-
Sasaki, Y., and J. Milbrandt. 2010. Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons. J. Biol. Chem. 285:41211-41215. http://dx.doi.org/10.1074/jbc.C110.193904
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 41211-41215
-
-
Sasaki, Y.1
Milbrandt, J.2
-
77
-
-
65649126738
-
Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide
-
Sasaki, Y., B.P. Vohra, F.E. Lund, and J. Milbrandt. 2009. Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. J. Neurosci. 29:5525-5535. http://dx.doi.org/10.1523/JNEUROSCI.5469-08.2009
-
(2009)
J. Neurosci.
, vol.29
, pp. 5525-5535
-
-
Sasaki, Y.1
Vohra, B.P.2
Lund, F.E.3
Milbrandt, J.4
-
78
-
-
34748819496
-
Mechanisms of axon degeneration: from development to disease
-
Saxena, S., and P. Caroni. 2007. Mechanisms of axon degeneration: from development to disease. Prog. Neurobiol. 83:174-191. http://dx.doi.org/10.1016/j.pneurobio.2007.07.007
-
(2007)
Prog. Neurobiol.
, vol.83
, pp. 174-191
-
-
Saxena, S.1
Caroni, P.2
-
79
-
-
0015900146
-
Effects of calcium ion concentration on the degeneration of amputated axons in tissue culture
-
Schlaepfer, W.W., and R.P. Bunge. 1973. Effects of calcium ion concentration on the degeneration of amputated axons in tissue culture. J. Cell Biol. 59:456-470. http://dx.doi.org/10.1083/jcb.59.2.456
-
(1973)
J. Cell Biol.
, vol.59
, pp. 456-470
-
-
Schlaepfer, W.W.1
Bunge, R.P.2
-
80
-
-
77951870448
-
Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals
-
Schoenmann, Z., E. Assa-Kunik, S. Tiomny, A. Minis, L. Haklai-Topper, E. Arama, and A. Yaron. 2010. Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals. J. Neurosci. 30:6375-6386. http://dx.doi.org/10.1523/JNEUROSCI.0922-10.2010
-
(2010)
J. Neurosci.
, vol.30
, pp. 6375-6386
-
-
Schoenmann, Z.1
Assa-Kunik, E.2
Tiomny, S.3
Minis, A.4
Haklai-Topper, L.5
Arama, E.6
Yaron, A.7
-
81
-
-
0037614919
-
Neurites undergoing Wallerian degeneration show an apoptotic-like process with Annexin V positive staining and loss of mitochondrial membrane potential
-
Sievers, C., N. Platt, V.H. Perry, M.P. Coleman, and L. Conforti. 2003. Neurites undergoing Wallerian degeneration show an apoptotic-like process with Annexin V positive staining and loss of mitochondrial membrane potential. Neurosci. Res. 46:161-169. http://dx.doi.org/10.1016/S0168-0102(03)00039-7
-
(2003)
Neurosci. Res.
, vol.46
, pp. 161-169
-
-
Sievers, C.1
Platt, N.2
Perry, V.H.3
Coleman, M.P.4
Conforti, L.5
-
82
-
-
0027213846
-
Persistence of axonal transport in isolated axons of the mouse
-
Smith, R.S., and M.A. Bisby. 1993. Persistence of axonal transport in isolated axons of the mouse. Eur. J. Neurosci. 5:1127-1135. http://dx.doi.org/10.1111/j.1460-9568.1993.tb00967.x
-
(1993)
Eur. J. Neurosci.
, vol.5
, pp. 1127-1135
-
-
Smith, R.S.1
Bisby, M.A.2
-
83
-
-
34247500849
-
Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis
-
Sorci, L., F. Cimadamore, S. Scotti, R. Petrelli, L. Cappellacci, P. Franchetti, G. Orsomando, and G. Magni. 2007. Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. Biochemistry. 46:4912-4922. http://dx.doi.org/10.1021/bi6023379
-
(2007)
Biochemistry
, vol.46
, pp. 4912-4922
-
-
Sorci, L.1
Cimadamore, F.2
Scotti, S.3
Petrelli, R.4
Cappellacci, L.5
Franchetti, P.6
Orsomando, G.7
Magni, G.8
-
84
-
-
0037430098
-
Critical calpaindependent ultrastructural alterations underlie the transformation of an axonal segment into a growth cone after axotomy of cultured Aplysia neurons
-
Spira, M.E., R. Oren, A. Dormann, and D. Gitler. 2003. Critical calpaindependent ultrastructural alterations underlie the transformation of an axonal segment into a growth cone after axotomy of cultured Aplysia neurons. J. Comp. Neurol. 457:293-312. http://dx.doi.org/10.1002/cne.10569
-
(2003)
J. Comp. Neurol.
, vol.457
, pp. 293-312
-
-
Spira, M.E.1
Oren, R.2
Dormann, A.3
Gitler, D.4
-
85
-
-
77950518136
-
Mechanisms of axonal injury: internodal nanocomplexes and calcium deregulation
-
Stirling, D.P., and P.K. Stys. 2010. Mechanisms of axonal injury: internodal nanocomplexes and calcium deregulation. Trends Mol. Med. 16:160-170. http://dx.doi.org/10.1016/j.molmed.2010.02.002
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 160-170
-
-
Stirling, D.P.1
Stys, P.K.2
-
86
-
-
65549152473
-
NAD+ activates KNa channels in dorsal root ganglion neurons
-
Tamsett, T.J., K.E. Picchione, and A. Bhattacharjee. 2009. NAD+ activates KNa channels in dorsal root ganglion neurons. J. Neurosci. 29:5127-5134. http://dx.doi.org/10.1523/JNEUROSCI.0859-09.2009
-
(2009)
J. Neurosci.
, vol.29
, pp. 5127-5134
-
-
Tamsett, T.J.1
Picchione, K.E.2
Bhattacharjee, A.3
-
87
-
-
79955723836
-
Dendrites have a rapid program of injuryinduced degeneration that is molecularly distinct from developmental pruning
-
Tao, J., and M.M. Rolls. 2011. Dendrites have a rapid program of injuryinduced degeneration that is molecularly distinct from developmental pruning. J. Neurosci. 31:5398-5405. http://dx.doi.org/10.1523/JNEUROSCI.3826-10.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 5398-5405
-
-
Tao, J.1
Rolls, M.M.2
-
88
-
-
0028353605
-
Loss of the compound action potential: an electrophysiological, biochemical and morphological study of early events in axonal degeneration in the C57BL/Ola mouse
-
Tsao, J.W., M.C. Brown, M.J. Carden, W.G. McLean, and V.H. Perry. 1994. Loss of the compound action potential: an electrophysiological, biochemical and morphological study of early events in axonal degeneration in the C57BL/Ola mouse. Eur. J. Neurosci. 6:516-524. http://dx.doi.org/10.1111/j.1460-9568.1994.tb00295.x
-
(1994)
Eur. J. Neurosci.
, vol.6
, pp. 516-524
-
-
Tsao, J.W.1
Brown, M.C.2
Carden, M.J.3
McLean, W.G.4
Perry, V.H.5
-
89
-
-
0033564778
-
Temperature modulation reveals three distinct stages of Wallerian degeneration
-
Tsao, J.W., E.B. George, and J.W. Griffin. 1999. Temperature modulation reveals three distinct stages of Wallerian degeneration. J. Neurosci. 19:4718-4726.
-
(1999)
J. Neurosci.
, vol.19
, pp. 4718-4726
-
-
Tsao, J.W.1
George, E.B.2
Griffin, J.W.3
-
90
-
-
34547652325
-
Why is Wallerian degeneration in the CNS so slow?
-
Vargas, M.E., and B.A. Barres. 2007. Why is Wallerian degeneration in the CNS so slow? Annu. Rev. Neurosci. 30:153-179. http://dx.doi.org/10.1146/annurev.neuro.30.051606.094354
-
(2007)
Annu. Rev. Neurosci.
, vol.30
, pp. 153-179
-
-
Vargas, M.E.1
Barres, B.A.2
-
91
-
-
82755168795
-
Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxicnecrotic cell death
-
Verghese, P.B., Y. Sasaki, D. Yang, F. Stewart, F. Sabar, M.B. Finn, C.M. Wroge, S. Mennerick, J.J. Neil, J. Milbrandt, and D.M. Holtzman. 2011. Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxicnecrotic cell death. Proc. Natl. Acad. Sci. USA. 108:19054-19059. http://dx.doi.org/10.1073/pnas.1107325108
-
(2011)
Proc. Natl. Acad. Sci. USA.
, vol.108
, pp. 19054-19059
-
-
Verghese, P.B.1
Sasaki, Y.2
Yang, D.3
Stewart, F.4
Sabar, F.5
Finn, M.B.6
Wroge, C.M.7
Mennerick, S.8
Neil, J.J.9
Milbrandt, J.10
Holtzman, D.M.11
-
92
-
-
12944314765
-
Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons
-
Verkhratsky, A. 2005. Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol. Rev. 85:201-279. http://dx.doi.org/10.1152/physrev.00004.2004
-
(2005)
Physiol. Rev.
, vol.85
, pp. 201-279
-
-
Verkhratsky, A.1
-
93
-
-
77958026084
-
Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway
-
Vohra, B.P., Y. Sasaki, B.R. Miller, J. Chang, A. DiAntonio, and J. Milbrandt. 2010. Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway. J. Neurosci. 30:13729-13738. http://dx.doi.org/10.1523/JNEUROSCI.2939-10.2010
-
(2010)
J. Neurosci.
, vol.30
, pp. 13729-13738
-
-
Vohra, B.P.1
Sasaki, Y.2
Miller, B.R.3
Chang, J.4
DiAntonio, A.5
Milbrandt, J.6
-
94
-
-
0001754953
-
Experiments on the section of the glossopharyngeal and hypoglossal nerves of the frog, and observations of the alterations produced thereby in the structure of their primitive fibres
-
Waller, A. 1850. Experiments on the section of the glossopharyngeal and hypoglossal nerves of the frog, and observations of the alterations produced thereby in the structure of their primitive fibres. Philos. Trans. R. Soc. Lond. 140:423-429. http://dx.doi.org/10.1098/rstl.1850.0021
-
(1850)
Philos. Trans. R. Soc. Lond.
, vol.140
, pp. 423-429
-
-
Waller, A.1
-
95
-
-
0033922514
-
Pathogenesis of axonal degeneration: parallels between Wallerian degeneration and vincristine neuropathy
-
Wang, M.S., Y. Wu, D.G. Culver, and J.D. Glass. 2000. Pathogenesis of axonal degeneration: parallels between Wallerian degeneration and vincristine neuropathy. J. Neuropathol. Exp. Neurol. 59:599-606.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 599-606
-
-
Wang, M.S.1
Wu, Y.2
Culver, D.G.3
Glass, J.D.4
-
96
-
-
0034747230
-
The WldS protein protects against axonal degeneration: a model of gene therapy for peripheral neuropathy
-
Wang, M.S., G. Fang, D.G. Culver, A.A. Davis, M.M. Rich, and J.D. Glass. 2001. The WldS protein protects against axonal degeneration: a model of gene therapy for peripheral neuropathy. Ann. Neurol. 50:773-779. http://dx.doi.org/10.1002/ana.10039
-
(2001)
Ann. Neurol
, vol.50
, pp. 773-779
-
-
Wang, M.S.1
Fang, G.2
Culver, D.G.3
Davis, A.A.4
Rich, M.M.5
Glass, J.D.6
-
97
-
-
1642309633
-
Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions
-
Wang, Q., C. Song, and C.C. Li. 2004. Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions. J. Struct. Biol. 146:44-57. http://dx.doi.org/10.1016/j.jsb.2003.11.014
-
(2004)
J. Struct. Biol.
, vol.146
, pp. 44-57
-
-
Wang, Q.1
Song, C.2
Li, C.C.3
-
98
-
-
23744474976
-
A local mechanism mediates NAD-dependent protection of axon degeneration
-
Wang, J., Q. Zhai, Y. Chen, E. Lin, W. Gu, M.W. McBurney, and Z. He. 2005. A local mechanism mediates NAD-dependent protection of axon degeneration. J. Cell Biol. 170:349-355. http://dx.doi.org/10.1083/jcb.200504028
-
(2005)
J. Cell Biol.
, vol.170
, pp. 349-355
-
-
Wang, J.1
Zhai, Q.2
Chen, Y.3
Lin, E.4
Gu, W.5
McBurney, M.W.6
He, Z.7
-
99
-
-
0038198738
-
Axon pruning during Drosophila metamorphosis: evidence for local degeneration and requirement of the ubiquitin-proteasome system
-
Watts, R.J., E.D. Hoopfer, and L. Luo. 2003. Axon pruning during Drosophila metamorphosis: evidence for local degeneration and requirement of the ubiquitin-proteasome system. Neuron. 38:871-885. http://dx.doi.org/10.1016/S0896-6273(03)00295-2
-
(2003)
Neuron
, vol.38
, pp. 871-885
-
-
Watts, R.J.1
Hoopfer, E.D.2
Luo, L.3
-
100
-
-
0035869473
-
Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels
-
Wolf, J.A., P.K. Stys, T. Lusardi, D. Meaney, and D.H. Smith. 2001. Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels. J. Neurosci. 21:1923-1930.
-
(2001)
J. Neurosci.
, vol.21
, pp. 1923-1930
-
-
Wolf, J.A.1
Stys, P.K.2
Lusardi, T.3
Meaney, D.4
Smith, D.H.5
-
101
-
-
78649729117
-
Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose
-
Wright, A.K., T.M. Wishart, C.A. Ingham, and T.H. Gillingwater. 2010. Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose. PLoS ONE. 5:e15108. http://dx.doi.org/10.1371/journal.pone.0015108
-
(2010)
PLoS ONE
, vol.5
-
-
Wright, A.K.1
Wishart, T.M.2
Ingham, C.A.3
Gillingwater, T.H.4
-
102
-
-
66049102890
-
Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration
-
Yahata, N., S. Yuasa, and T. Araki. 2009. Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration. J. Neurosci. 29:6276-6284. http://dx.doi.org/10.1523/JNEUROSCI.4304-08.2009
-
(2009)
J. Neurosci.
, vol.29
, pp. 6276-6284
-
-
Yahata, N.1
Yuasa, S.2
Araki, T.3
-
103
-
-
73449100102
-
Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity
-
Yan, T., Y. Feng, J. Zheng, X. Ge, Y. Zhang, D. Wu, J. Zhao, and Q. Zhai. 2010. Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity. Neurochem. Int. 56:101-106. http://dx.doi.org/10.1016/j.neuint.2009.09.007
-
(2010)
Neurochem. Int.
, vol.56
, pp. 101-106
-
-
Yan, T.1
Feng, Y.2
Zheng, J.3
Ge, X.4
Zhang, Y.5
Wu, D.6
Zhao, J.7
Zhai, Q.8
-
104
-
-
33845477523
-
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity
-
Zhai, R.G., Y. Cao, P.R. Hiesinger, Y. Zhou, S.Q. Mehta, K.L. Schulze, P. Verstreken, and H.J. Bellen. 2006. Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PLoS Biol. 4:e416. http://dx.doi.org/10.1371/journal.pbio.0040416
-
(2006)
PLoS Biol
, vol.4
-
-
Zhai, R.G.1
Cao, Y.2
Hiesinger, P.R.3
Zhou, Y.4
Mehta, S.Q.5
Schulze, K.L.6
Verstreken, P.7
Bellen, H.J.8
-
105
-
-
42249103603
-
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
-
Zhai, R.G., F. Zhang, P.R. Hiesinger, Y. Cao, C.M. Haueter, and H.J. Bellen. 2008. NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature. 452:887-891. http://dx.doi.org/10.1038/nature06721
-
(2008)
Nature
, vol.452
, pp. 887-891
-
-
Zhai, R.G.1
Zhang, F.2
Hiesinger, P.R.3
Cao, Y.4
Haueter, C.M.5
Bellen, H.J.6
-
106
-
-
0042848910
-
Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration
-
Zhai, Q., J. Wang, A. Kim, Q. Liu, R. Watts, E. Hoopfer, T. Mitchison, L. Luo, and Z. He. 2003. Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration. Neuron. 39:217-225. http://dx.doi.org/10.1016/S0896-6273(03)00429-X
-
(2003)
Neuron
, vol.39
, pp. 217-225
-
-
Zhai, Q.1
Wang, J.2
Kim, A.3
Liu, Q.4
Watts, R.5
Hoopfer, E.6
Mitchison, T.7
Luo, L.8
He, Z.9
-
107
-
-
0027330011
-
Spatiotemporal distribution of Ca2+ following axotomy and throughout the recovery process of cultured Aplysia neurons
-
Ziv, N.E., and M.E. Spira. 1993. Spatiotemporal distribution of Ca2+ following axotomy and throughout the recovery process of cultured Aplysia neurons. Eur. J. Neurosci. 5:657-668. http://dx.doi.org/10.1111/j.1460-9568.1993.tb00531.x
-
(1993)
Eur. J. Neurosci.
, vol.5
, pp. 657-668
-
-
Ziv, N.E.1
Spira, M.E.2
|