Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents

European Journal of Medicinal Chemistry

Volumn 119, Issue , 2016, Pages 132-140

  Belmonte Reche, Efres ^a   Martínez García, Marta ^a   Peñalver, Pablo ^a,b   Gómez Pérez, Verónica ^a   Lucas, Ricardo ^a,b   Gamarro, Francisco ^a   Pérez Victoria, José María ^a   Morales, Juan Carlos ^a,b  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Antileishmanial; Antitrypanosomal; Hydroxytyrosol; Tyrosol

Indexed keywords

(3,4 BIS((4 METHOXYBENZYL)OXY) PHENETHYL)(DODECYL)SULFANE; (3,4 BIS(BENZYLOXY)PHENETHYL)(DODECYL) SULFANE; 1 (3,4 DIHYDROXYPHENETHYL) 3 DECYLTHIOUREA; 1 (3,4 DIHYDROXYPHENETHYL) 3 DODECYLTHIOUREA; 1,2 BIS((4,4' METHOXYBENZYL)OXY) 4 (2 (DECYLOXY)ETHYL)BENZENE; 2 (3,4 BIS(4 METHOXYBENZYLOXY)PHENYL) ETHAN 1 OL; 2 (3,4 BIS(BENZYLOXY)PHENYL)ETHAN 1 OL; 2 (BENZO[D][1,3]DIOXOL 5 YL)ETHYL DECANOATE; 2 (BENZO[D][1,3]DIOXOL 5 YL)ETHYL DODECANOATE; 3,4 BIS((4 METHOXYBENZYL)OXY)PHENETHYL 4 METHYLBENZENESULFONATE; 3,4 BIS(BENZYLOXY)PHENETHYL 4 METHYLBENZENESULFONATE; 4 (2 ISOTHIOCYANATOETHYL)BENZENE 1,2 DIOL; AMPHOTERICIN B; ANTILEISHMANIAL AGENT; ANTITRYPANOSOMAL AGENT; DECANOIC ACID; EFLORNITHINE; ESTER; ETHER DERIVATIVE; FATTY ACID ESTER; HYDROXYTYROSOL; PHENOL; SURAMIN; THIOUREA DERIVATIVE; TYROSOL; UNCLASSIFIED DRUG; 3,4-DIHYDROXYPHENYLETHANOL; 4-HYDROXYPHENYLETHANOL; PHENETHYL ALCOHOL;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC50; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; SELECTIVITY INDEX; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; ANALOGS AND DERIVATIVES; CELL LINE; CHEMISTRY; DRUG EFFECTS; TRYPANOSOMA BRUCEI BRUCEI;

CELL LINE; HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; PHENYLETHYL ALCOHOL; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84968645234     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2016.04.047     Document Type: Article

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