Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity

Natural Product Communications

Volumn 7, Issue 6, 2012, Pages 753-755

  Moradi Afrapoli, Fahimeh ^a,b   Yassa, Nargues ^a   Zimmermann, Stefanie ^c,d   Saeidnia, Soodabeh ^a   Hadjiakhoondi, Abbas ^a   Ebrahimi, Samad N ^c   Hamburger, Matthias ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c UNIVERSITY OF BASEL   (Switzerland)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Cinnamoylphenethyl amide; Polygonaceae; Polygonum hyrcanicum; Trypanosoma brucei rhodesiense

Indexed keywords

ANTITRYPANOSOMAL AGENT; CANNABISIN B; CINNAMOYLPHENETHYL AMIDE DERIVATIVE; FERULIC ACID; MELARSOPROL; METHANOL; N 3,4 DIMETHOXYCINNAMOYLDOPAMINE; N 4 COUMAROYLTYRAMINE; N CAFFEOYLTYRAMINE; N FERULOYLTYRAMINE; PARA COUMARIC ACID; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PODOPHYLLOTOXIN; POLYGONUM HYRCANICUM EXTRACT; TYROSOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTI TRYPANOSOMAL ACTIVITY; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; FRACTIONATION; IC 50; IRAN; NONHUMAN; PHYTOCHEMISTRY; POLYGONUM; POLYGONUM HYRCANICUM; RAT; TRYPANOSOMA RHODESIENSE;

POLYGONACEAE; POLYGONUM; TRYPANOSOMA BRUCEI RHODESIENSE;

EID: 84864695644     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1200700616     Document Type: Article

References (22)

1. Kennedy PGE. (2004) Human African trypanosomiasis of the CNS: current issues and challenges. Journal of Clinical Investigation, 113, 496-504.
2. Mozaffarian V. (2007) A dictionary of Iranian plant names. Farhang Moaser, Tehran, 423.
3. Ghorbani A. (2005) Studies on pharmaceutical ethnobotany in the region of Turkmen Sahra, north of Iran (part 1): General results. Journal of Ethnopharmacology, 102, 58-68.
4. Pedersen HA, Steffensen SK, Christophersen C. (2010) Cinnamoylphenethylamine 1H-NMR chemical shifts: a concise reference for ubiquitous compounds. Natural Product Communications, 5, 1259-1262.
5. Pedersen HA, Steffensen SK, Christophersen C, Mortensen AG, Jorgensen LN, Niveyro S, de Trolani RM, Rodriguez-Enriquez RJ, Barba de la Rosa AP, Fomsgaard IS.(2010) Synthesis and quantitation of six phenolic amides in Amaranthus spp. Journal of Agricultural and Food Chemistry, 58, 6306-6311.
6. Martin-Tanguy J, Cabanne F, Perdrizet E, Martin C. (1978) The distribution of hydroxycinnamic acid amides in flowering plants. Phytochemistry, 17, 1927-1928.
7. Sakakibara I, Ikeya Y, Hayashi K, Mitsuhashi H. (1992) Three phenyldihydronaphtalene lignanamides from fruits of Cannabis sativa. Phytochemistry, 31, 3219-3223.
8. Ma CY, Liu WK, Che CT. (2002) Lignanamides and nonalkaloidal components of Hyoscyamus niger seeds. Journal of Natural Products, 65, 206-209. (Pubitemid 34171184)
9. Lajide L, Escoubas P, Mizutani J. (1995) Termite antifeedant activity from tropical plants. 1. Termite antifeedant activity in Xylopia aethiopica. Phytochemistry, 40, 1105-1112.
10. Ge F, Tang CP, Ye Y. (2008) Lignanamides and sesquiterpenoids from stems of Mitrephora thorelii. Helvetica Chimica Acta, 91, 1023-1030.
11. Tomosaka H, Chin YW, Salim AA, Keller WJ, Chai H, Kinghorn AD. (2008) Antioxidant and cytoprotective compounds from Berberis vulgaris (Barberry). Phytotherapy Research, 22, 979-981.
12. Li Y, He X, Liu Z, Zhou W, Lan Y, Wang A, Wang Y. (2010) Chemical constituents of flowers of Polygonum orientale. Shizhen Guoyi Guoyao, 21, 14-15.
13. Fan P, Terrier L, Hay AE, Marston A, Hostettmann K. (2010) Antioxidant and enzyme inhibition activities and chemical profiles of Polygonum sachalinensis F.Schmidt ex Maxim (Polygonaceae). Fitoterapia, 81, 124-131.
14. Michalet S, Cartier G, David B, Mariotte AM, Dijoux-franca MG, Kaatz GW, Stavri M, Gibbons S. (2007) N-caffeoylamide derivatives as bacterial efflux pump inhibitors. Bioorganic & Medicinal Chemistry Letters, 17, 1755-1758.
15. Tang GH, Chen DM, Qiu BY, Sheng L, Wang YH, Hu GW, Zhao FW, Ma LJ, Wang H, Huang QQ, Xu JJ, Long CL, Li J. (2011) Cytotoxic amide alkaloids from Piper boehmeriaefolium. Journal of Natural Products, 74, 45-49.
16. Pan PC, Cheng MJ, Peng CF, Huang HY, Chen JJ, Chen IS. (2010) Secondary metabolites from the roots of Litsea hypophaea and their antitubercular activity. Journal of Natural Products, 73, 890-896.
17. Song S, Li Y, Feng Z, Jiang J, Zhang P. (2010) Hepatoprotective constituents from the roots and stems of Erycibe hainanensis. Journal of Natural Products, 73, 177-184.
18. Okombi S, Rival D, Bonnet S, Mariotte AM, Perrier E, Boumendjel A. (2006) Analogues of N-hydroxycinnamoylphenalkylamides as inhibitors of human melanocyte-tyrosinase. Bioorganic & Medicinal Chemistry Letters, 16, 2252-2255. (Pubitemid 43351089)
19. Park JB. (2007) Caffedymine from Cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P selectin. Journal of Agricultural and Food Chemistry, 55, 2171-2175.
20. Park JB, Schoene N. (2006) Clovamide-type phenylpropenoic acid amides, N-coumaroyldopamine and N-caffeoyldopamine, inhibit platelet-leukocyte interactions via suppressing P-selectin expression. Journal of Pharmacology and Experimental Therapeutics, 317, 813-819.
21. Baltz T, Baltz D, Giroud C, Crockett J. (1985) Cultivation in a semi-defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense. EMBO Journal, 4, 1273-1277.
22. Julianti T, Hata Y, Zimmermann S, Kaiser M, Hamburger M, Adams M. (2011) Antitrypanosomal sesquiterpene lactones from Saussurea costus. Fitoterapia, 82, 955-959.