Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis

Biochemical Journal

Volumn 450, Issue 1, 2013, Pages 127-139

  Dutta, Debajyoti ^a,b   Bhattacharyya, Sudipta ^a   Roychowdhury, Amlan ^a   Biswas, Rupam ^a   Das, Amit Kumar ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY   (India)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

oxoacyl reductase; Co operativity; Hexanoyl CoA; Mycobacterium tuberculosis; Short chain dehydrogenase reductase

Indexed keywords

ACYL COENZYME A; ARGININE; BACTERIAL ENZYME; COENZYME A; DIMER; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); FABG4 ENZYME; HEXANOYL COENZYME A; MONOMER; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; PANTETHEINE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TERNARY COMPLEX FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; COMPLEX FORMATION; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR MIMICRY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS;

ACYL COENZYME A; ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; ARGININE; BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; NAD; SUBSTRATE SPECIFICITY;

EID: 84873042433     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121107     Document Type: Article

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