Neuroprotective effect of alkyl hydroxytyrosyl ethers in rat brain slices subjected to a hypoxia-reoxygenation model

Food Chemistry

Volumn 134, Issue 4, 2012, Pages 2176-2183

  Guerrero, A ^a   De La Cruz, J P ^a   Munoz Marin J ^a   Lopez Villodres J A ^a   Madrona, A ^b   Espartero, J L ^b   Gonzalez Correa J A ^a  

^a UNIVERSITY OF MÁLAGA   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Hydroxytyrosol; Neuroprotection; Oxidative stress; Virgin olive oil

Indexed keywords

ANTIOXIDANT EFFECT; CARBON CHAINS; EXPERIMENTAL MODELS; FERROUS SALTS; GLUTATHIONE CONCENTRATION; HYDROXYTYROSOL; INHIBITORY CONCENTRATION; LIPID PEROXIDATION; NEUROPROTECTION; NEUROPROTECTIVE EFFECTS; RAT BRAIN; VIRGIN OLIVE OIL;

ETHERS; ORGANIC COMPOUNDS; RATS; VEGETABLE OILS;

OXIDATIVE STRESS;

ALKYL HYDROXYTYROSYL ETHER DERIVATIVE; ANTIOXIDANT; DIETHYLMALEATE; ETHER DERIVATIVE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROXYTYROSOL; HYDROXYTYROSYL BUTYL ETHER; HYDROXYTYROSYL DODECYL ETHER; HYDROXYTYROSYL ETHYL ETHER; HYDROXYTYROSYL HEXYL ETHER; HYDROXYTYROSYL OCTYL ETHER; MALEIC ACID; NEUROPROTECTIVE AGENT; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; HYPOXIA; IC 50; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; REOXYGENATION;

ANIMALS; ANOXIA; BRAIN; ETHERS; GLUTATHIONE; LIPID PEROXIDATION; MALE; MODELS, BIOLOGICAL; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; OXYGEN; PHENYLETHYL ALCOHOL; RATS; RATS, WISTAR;

RATTUS;

EID: 84861577169     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.04.022     Document Type: Article

References (44)

1. R. Agarwal, and G.L. Shukla Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat Neurochemical Research 24 1999 1507 1514
2. F. Barzi, M. Woodward, R.M. Marfisi, L. Tavazzi, F. Valagussa, and R. Marchioli GISSI-prevenzione investigators, Mediterranean diet and all-causes mortality after myocardial infarction: Results from the GISSI-prevenzione trial European Journal of Clinical Nutrition 57 2003 604 611 (Pubitemid 36559491)
3. A. Bendini, L. Cerretani, A. Carrasco-Pancorbo, and A.M. Gomez-Caravaca Phenolic molecules in virgin olive oils: A survey of their sensory properties, health effects, antioxidant activity and analytical methods. An overview of the last decade Molecules 12 2007 1679 1719
4. C.M. Bitler, T.M. Viale, B. Damaj, and R. Crea Hydrolyzed olive vegetation water in mice has anti-inflammatory activity Journal of Nutrition 135 2005 1475 1479 (Pubitemid 40799613)
5. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dyebinding Analytical Biochemistry 72 1976 248 254
6. M. Brenes, A. Garcia, P. Garcia, J.J. Rios, and A. Garrido Phenolic compounds in Spanish olive oils Journal of Agricultural and Food Chemistry 47 1999 3535 3540 (Pubitemid 29449465)
7. L. Craggs, and R.N. Kalaria Revisiting dietary antioxidants, neurodegeneration and dementia Neuroreport 22 2011 1 3
8. J.P. De La Cruz, S. Del Río, M.M. Arrebola, J.A. López-Villodres, N. Jebrouni, and J.A. González-Correa Effect of virgin olive oil plus acetylsalicylic acid on brain slices damage after hypoxia-reoxygenation in rats with type 1-like diabetes mellitus Neuroscience Letters 471 2010 89 93
9. J.P. De La Cruz, A. Guerrero, J.A. González-Correa, M.M. Arrebola, and F. Sánchez de la Cuesta Antioxidant effect of acetylsalicylic and salicylic acid in rat brain slices subjected to hypoxia Journal of Neuroscience Research 75 2004 280 290 (Pubitemid 38049399)
10. M. De Lorgril, P. Salen, J.L. Martin, N. Mamelle, I. Monjaud, and P. Touboul Effect of a Mediterranean type diet on the rate of cardiovascular complications in patients with coronary artery disease Journal of American College of Cardiology 28 1996 1103 1108
11. R. Fabiani, R. Fuccelli, F. Pieravanti, A. De Bartolomeo, and G. Morozzi Production of hydrogen peroxide is responsible for the induction of apoptosis by hydroxytyrosol on HL60 cells Molecular Nutrition and Food Resesearch 53 2009 887 896
12. E. Gimeno, K. de la Torre-Carbot, R.M. Lamuela-Raventós, A.I. Castellote, M. Fitó, and R. de la Torre Changes in the phenolic content of low density lipoprotein after olive oil consumption in men. A randomized crossover controlled trial British Journal of Nutrition 98 2007 1243 1250 (Pubitemid 350193792)
13. J.A. González-Correa, J.A. López-Villodres, R. Asensi, J.L. Espartero, G. Rodríguez-Gutiérez, and J.P. De La Cruz Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: Comparison with hydroxytyrosol and acetylsalicylic acid British Journal of Nutrition 101 2009 1157 1164
14. J.A. González-Correa, J. Muñoz-Marín, M.M. Arrebola, A. Guerrero, F. Narbona, and J.A. López-Villodres Dietary virgin olive oil reduces oxidative stress and cellular damage in rat brain slices subjected to hypoxia-reoxygenation Lipids 42 2007 921 929 (Pubitemid 47585727)
15. J.A. González-Correa, M.D. Navas, J.A. Lopez-Villodres, M. Trujillo, J.L. Espartero, and J.P. De La Cruz Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia-reoxygenation Neuroscience Letters 446 2008 143 146
16. J.A. González-Correa, M.D. Navas, J. Muñoz-Marín, M. Trujillo, J. Fernández-Bolaños, and J.P. De La Cruz Effects of hydroxytyrosol and hydroxytyrosol acetate administration to rats on platelet function compared to acetylsalicylic acid Journal of Agricultural and Food Chemistry 56 2008 7872 7876
17. L. Goya, R. Mateos, and L. Bravo Effect of the olive oil phenol hydroxytyrosol on human hepatoma HepG2 cells. Protection against oxidative stress induced by tert-butylhydroperoxide European Journal of Nutrition 46 2007 70 78 (Pubitemid 46295311)
18. C. Guichard, E. Pedruzzi, M. Fay, J.C. Marie, F. Braut-Boucher, and F. Daniel Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells Carcinogenesis 27 2006 1812 1827 (Pubitemid 44288663)
19. P.J. Hissin, and R. Hilf A fluorometric method for determination of oxidized and reduced glutathione in tissues Analytical Biochemistry 74 1976 214 226
20. C.D. Kamat, S. Gadal, M. Mhatre, K.S. Williamson, Q.N. Pye, and K. Hensley Antioxidants in central nervous system diseases: Preclinical promise and translational challenges Journal of Alzheimers Disease 15 2008 473 493
21. K.T. Knoops, L.C. De Groot, F. Fidanza, A. Alberti-Fidanza, D. Kromhout, and W.A. van Staveren Comparison of three different dietary scores in relation to 10-year mortality in elderly European subjects: The HALE project European Journal of Clinical Nutrition 60 2006 746 755 (Pubitemid 43842230)
22. M. Laguerre, L.J. López Giraldo, J. Lecomte, M.C. Figueroa-Espinoza, and B. Baréa Relationship between hydrophobicity and antioxidant ability of "phenolipids" in emulsion: A parabolic effect of the chain length of rosmarinate esters Journal of Agricultural and Food Chemistry 58 2010 2869 2876
23. P. Lorenz, M. Zeh, J. Martens-Lobenhoffer, H. Schmidt, G. Wolf, and T.F. Horn Natural and newly synthesized hydroxy-1-aryl-isochromans: A class of potential antioxidants and radical scavengers Free Radical Research 39 2005 535 545 (Pubitemid 40711887)
24. A. Madrona, G. Pereira-Caro, R. Mateos, G. Rodríguez, M. Trujillo, and J. Fernández-Bolaños Synthesis of hydroxytyrosyl alkyl ethers from olive oil waste waters Molecules 14 2009 1762 1772
25. M.A. Martinez-Gonzalez The SUN cohort study (Seguimiento University of Navarra) Public Health Nutrition 9 2006 127 131
26. G. Montedoro, M. Servili, M. Baldioli, R. Selvaggini, E. Miniati, and A. Macchioni Simple and hydrolyzable compounds in virgen olive oil. Spectroscopic characterizations of the secoiridoid derivatives Journal of Agricultural and Food Chemistry 41 1993 2228 2234
27. F. Paiva-Martins, J. Fernandes, V. Santos, L. Silva, F. Borges, and S. Rocha Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-induced hemolysis Journal of Agricultural and Food Chemistry 58 2010 135 140
28. G. Pereira-Caro, L. Bravo, A. Madrona, J.L. Espartero, and R. Mateos Uptake and metabolism of new synthetic lipophilic derivatives, hydroxytyrosyl ethers, by human hepatoma HepG2 cells Journal of Agricultural and Food Chemistry 58 2010 798 806
29. G. Pereira-Caro, A. Madrona, L. Bravo, J.L. Espartero, F. Alcudia, and A. Cert Antioxidant activity evaluation of alkyl hydroxytyrosyl ethers, a new class of hydroxytyrosol derivatives Food Chemistry 115 2009 86 91
30. G. Pereira-Caro, R. Mateos, S. Saha, A. Madrona, J.L. Espartero, and L. Bravo Transepithelial transport and metabolism of new lipophilic ether derivatives of hydroxytyrosol by enterocyte-like Caco-2/TC7 cells Journal of Agricultural and Food Chemistry 58 2010 11501 11509
31. G. Pereira-Caro, B. Sarriá, A. Madrona, J.L. Espartero, L. Goya, and L. Bravo Alkyl hydroxytyrosyl ethers show protective effects against oxidative stress in HepG2 cells Journal of Agricultural and Food Chemistry 59 2011 5964 5976
32. P. Sahota, and S.I. Savitz Investigational therapies for ischemic stroke: Neuroprotection and neurorecovery Neurotherapeutics 8 2001 434 451
33. S. Schaffer, W.E. Müller, and G.P. Eckert Cytoprotective effects of olive mill wastewater extract and its main constituent hydroxytyrosol in PC12 cells Pharmacological Research 62 2010 322 327
34. S. Schaffer, M. Podstawa, F. Visioli, P. Bogani, W.E. Müller, and G.P. Eckert Hydroxytyrosol-rich olive mill wastewater protects brain cells in vitro and ex vivo Journal of Agricultural and Food Chemistry 55 2007 5043 5049 (Pubitemid 47056055)
35. A. Serra, L. Rubió, X. Borrás, A. Macià, M.-P. Romeri, and M.J. Motilva Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake Molecular Nutrition 55 2011 1 11
36. A. Simonyi, Q. Wang, R.L. Miller, M. Yusof, P.B. Shelat, and A.Y. Sun Polyphenols in cerebral ischemia: Novel targets for neuroprotection Molecular Neurobiology 31 2005 135 147 (Pubitemid 41271199)
37. D. Tofani, V. Balducci, T. Gasperi, S. Incerpi, and A. Gambacorta Fatty acid hydroxytyrosyl esters: Structure/antioxidant activity relationship by ABTS and in cell-culture DCF assays Journal of Agricultural and Food Chemistry 58 2010 5292 5299
38. A. Trichopoulou, P. Orfanos, T. Norat, B. Bueno-de-Mesquita, M.C. Ocke, and P.H. Peeters Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study British Medical Journal 330 2005 991 998
39. E. Trípoli, M. Giammanco, G. Tabacchi, D. Di Majo, S. Giammanco, and M. La Guardia The phenolic compounds of olive oil: Structure, biological activity and beneficial effects on human health Nutrition Research Reviews 18 2005 98 112 (Pubitemid 40826917)
40. M. Trujillo, R. Mateos, L. Collantes de Teran, J.L. Espartero, R. Cert, and M. Jover Lipophilic hydroxytyrosyl esters. Antioxidant activity in lipid matrices and biological systems Journal of Agricultural and Food Chemistry 54 2006 3779 3785 (Pubitemid 44030555)
41. K.L. Tuck, and P.J. Hayball Major phenolic compounds in olive oil: Metabolism and health effects The Journal of Nutritional Biochemistry 13 2002 636 644 (Pubitemid 35341709)
42. X. Zhang, J. Cao, L. Jiang, and L. Zhong Suppressive effects of hydroxytyrosol on oxidative stress and nuclear factor-kappa B activation in THP-1 cells Biological & Pharmacological Bulletin 32 2009 578 582
43. X. Zhang, J. Cao, and L. Zhong Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells Naunyn Schmiedebergs Archives of Pharmacology 379 2009 581 586
44. X. Zhang, L. Jiang, C. Geng, J. Cao, and L. Zhong The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells Toxicon 54 2009 513 518