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Volumn 7, Issue APR2016, 2016, Pages

The CRISPR/Cas genome-editing tool: Application in improvement of crops

Author keywords

Cas9 sgRNA; CRISPR; DCas9; GE crops; NPBTs; Plant genome editing; RGENs

Indexed keywords


EID: 84964310738     PISSN: None     EISSN: 1664462X     Source Type: Journal    
DOI: 10.3389/fpls.2016.00506     Document Type: Review
Times cited : (207)

References (120)
  • 3
    • 84949935802 scopus 로고    scopus 로고
    • Activity and specificity of TRV-mediated gene editing in plants
    • Ali, Z., Abul-Faraj, A., Piatek, M., and Mahfouz, M. M. (2015b). Activity and specificity of TRV-mediated gene editing in plants. Plant Signal. Behav. 10: e1044191. doi: 10. 1080/15592324. 2015. 1044191
    • (2015) Plant Signal. Behav , vol.10
    • Ali, Z.1    Abul-Faraj, A.2    Piatek, M.3    Mahfouz, M.M.4
  • 4
    • 84908508061 scopus 로고    scopus 로고
    • Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
    • Anders, C., Niewoehner, O., Duerst, A., and Jinek, M. (2014). Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease. Nature 513, 569-573. doi: 10. 1038/nature13579
    • (2014) Nature , vol.513 , pp. 569-573
    • Anders, C.1    Niewoehner, O.2    Duerst, A.3    Jinek, M.4
  • 5
    • 84897532001 scopus 로고    scopus 로고
    • Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system
    • Anton, T., Bultmann, S., Leonhardt, H., and Markaki, Y. (2014). Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system. Nucleus 5, 163-172. doi: 10. 4161/nucl. 28488
    • (2014) Nucleus , vol.5 , pp. 163-172
    • Anton, T.1    Bultmann, S.2    Leonhardt, H.3    Markaki, Y.4
  • 6
    • 84924057826 scopus 로고    scopus 로고
    • Towards social acceptance of plant breeding by genome editing
    • Araki, M., and Ishii, T. (2015). Towards social acceptance of plant breeding by genome editing. Trends Plant Sci. 20, 145-149. doi: 10. 1016/j. tplants. 2015. 01. 010
    • (2015) Trends Plant Sci , vol.20 , pp. 145-149
    • Araki, M.1    Ishii, T.2
  • 8
    • 85009919974 scopus 로고    scopus 로고
    • Conferring resistance to geminiviruses with the CRISPR-Cas prokaryotic immune system
    • Baltes, N. J., Hummel, A. W., Konecna, E., Cegan, R., Bruns, A. N., Bisaro, D. M., et al. (2015). Conferring resistance to geminiviruses with the CRISPR-Cas prokaryotic immune system. Nat. Plants 1, 15145. doi: 10. 1038/nplants. 2015. 145
    • (2015) Nat. Plants , vol.1
    • Baltes, N.J.1    Hummel, A.W.2    Konecna, E.3    Cegan, R.4    Bruns, A.N.5    Bisaro, D.M.6
  • 9
    • 84876440888 scopus 로고    scopus 로고
    • CRISPR-Cas systems and RNA-guided interference
    • Barrangou, R. (2013). CRISPR-Cas systems and RNA-guided interference. Wiley Interdiscip. Rev. RNA 4, 267-278. doi: 10. 1002/wrna. 1159
    • (2013) Wiley Interdiscip. Rev. RNA , vol.4 , pp. 267-278
    • Barrangou, R.1
  • 10
    • 84885353478 scopus 로고    scopus 로고
    • Plant genome editing made easy: Targeted mutagenesis in model and crop plants using the CRISPR/Cas system
    • Belhaj, K., Chaparro-Garcia, A., Kamoun, S., and Nekrasov, V. (2013). Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system. Plant Methods 9, 39. doi: 10. 1186/1746-4811-9-39
    • (2013) Plant Methods , vol.9 , pp. 39
    • Belhaj, K.1    Chaparro-Garcia, A.2    Kamoun, S.3    Nekrasov, V.4
  • 12
    • 84920262090 scopus 로고    scopus 로고
    • The CRISPR/Cas9 system for plant genome editing and beyond
    • Bortesi, L., and Fischer, R. (2015). The CRISPR/Cas9 system for plant genome editing and beyond. Biotechnol. Adv. 33, 41-52. doi: 10. 1016/j. biotechadv. 2014. 12. 006
    • (2015) Biotechnol. Adv , vol.33 , pp. 41-52
    • Bortesi, L.1    Fischer, R.2
  • 13
    • 84893417192 scopus 로고    scopus 로고
    • Lignocellulosic feedstocks: Research progress and challenges in optimizing biomass quality and yield
    • Bosch, M., and Hazen, S. P. (2013). Lignocellulosic feedstocks: research progress and challenges in optimizing biomass quality and yield. Front. Plant Sci. 4: 474. doi: 10. 3389/fpls. 2013. 00474
    • (2013) Front. Plant Sci , vol.4 , pp. 474
    • Bosch, M.1    Hazen, S.P.2
  • 14
    • 84908584019 scopus 로고    scopus 로고
    • Efficient gene editing in tomato in the first generation using the CRISPR/Cas9 system
    • Brooks, C., Nekrasov, V., Lippman, Z., and Van Eck, J. (2014). Efficient gene editing in tomato in the first generation using the CRISPR/Cas9 system. Plant Physiol. 166, 1292-1297. doi: 10. 1104/pp. 114. 247577
    • (2014) Plant Physiol , vol.166 , pp. 1292-1297
    • Brooks, C.1    Nekrasov, V.2    Lippman, Z.3    Van Eck, J.4
  • 15
    • 84957112148 scopus 로고    scopus 로고
    • Generation and inheritance of targeted mutations in potato (Solanum tuberosum L.) Using the CRISPR/Cas System
    • Butler, N. M., Atkins, P. A., Voytas, D. F., and Douches, D. S. (2015). Generation and inheritance of targeted mutations in potato (Solanum tuberosum L.) Using the CRISPR/Cas System. PLoS ONE 10: e0144591. doi: 10. 1371/journal. pone. 0144591
    • (2015) PLoS ONE , vol.10
    • Butler, N.M.1    Atkins, P.A.2    Voytas, D.F.3    Douches, D.S.4
  • 16
    • 84942418558 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated genome editing in soybean hairy roots
    • Cai, Y., Chen, L., Liu, X., Sun, S., Wu, C., Jiang, B., et al. (2015). CRISPR/Cas9-mediated genome editing in soybean hairy roots. PLoS ONE 10: e0136064. doi: 10. 1371/journal. pone. 0136064
    • (2015) PLoS ONE , vol.10
    • Cai, Y.1    Chen, L.2    Liu, X.3    Sun, S.4    Wu, C.5    Jiang, B.6
  • 17
    • 84946416320 scopus 로고    scopus 로고
    • High-frequency, precise modification of the tomato genome
    • Cermak, T., Baltes, N. J., Cegan, R., Zhang, Y., and Voytas, D. F. (2015). High-frequency, precise modification of the tomato genome. Genome Biol. 16, 232. doi: 10. 1186/s13059-015-0796-9
    • (2015) Genome Biol , vol.16 , pp. 232
    • Cermak, T.1    Baltes, N.J.2    Cegan, R.3    Zhang, Y.4    Voytas, D.F.5
  • 18
    • 84947776272 scopus 로고    scopus 로고
    • Boosting plant immunity with CRISPR/Cas
    • Chaparro-Garcia, A., Kamoun, S., and Nekrasov, V. (2015). Boosting plant immunity with CRISPR/Cas. Genome Biol. 16, 254. doi: 10. 1186/s13059-015-0829-4
    • (2015) Genome Biol , vol.16 , pp. 254
    • Chaparro-Garcia, A.1    Kamoun, S.2    Nekrasov, V.3
  • 19
    • 84897964526 scopus 로고    scopus 로고
    • Targeted genome modification technologies and their applications in crop improvements
    • Chen, K., and Gao, C. (2014). Targeted genome modification technologies and their applications in crop improvements. Plant Cell Rep. 33, 575-583. doi: 10. 1007/s00299-013-1539-6
    • (2014) Plant Cell Rep , vol.33 , pp. 575-583
    • Chen, K.1    Gao, C.2
  • 20
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., et al. (2013). Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823. doi: 10. 1126/science. 1231143
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1    Ran, F.A.2    Cox, D.3    Lin, S.4    Barretto, R.5    Habib, N.6
  • 22
    • 84922664019 scopus 로고    scopus 로고
    • Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice
    • Endo, M., Mikami, M., and Toki, S. (2014). Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice. Plant Cell Physiol. 1, 1-7. doi: 10. 1093/pcp/pcu154
    • (2014) Plant Cell Physiol , vol.1 , pp. 1-7
    • Endo, M.1    Mikami, M.2    Toki, S.3
  • 23
    • 84937702694 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-mediated targeted mutagenesis in Populus in the first generation
    • Fan, D., Liu, T., Li, C., Jiao, B., Li, S., Hou, Y., et al. (2015). Efficient CRISPR/Cas9-mediated targeted mutagenesis in Populus in the first generation. Sci. Rep. 5, 12217. doi: 10. 1038/srep12217
    • (2015) Sci. Rep , vol.5
    • Fan, D.1    Liu, T.2    Li, C.3    Jiao, B.4    Li, S.5    Hou, Y.6
  • 24
    • 84904068340 scopus 로고    scopus 로고
    • Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana
    • Fauser, F., Schiml, S., and Puchta, H. (2014). Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana. Plant J. 79, 348-359. doi: 10. 1111/tpj. 12554
    • (2014) Plant J , vol.79 , pp. 348-359
    • Fauser, F.1    Schiml, S.2    Puchta, H.3
  • 25
    • 84896924524 scopus 로고    scopus 로고
    • Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis
    • Feng, Z., Mao, Y., Xu, N., Zhang, B., Wei, P., Yang, D.-L., et al. (2014). Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis. Proc. Natl. Acad. Sci. U. S. A. 111, 4632-4637. doi: 10. 1073/pnas. 1400822111
    • (2014) Proc. Natl. Acad. Sci. U. S. A , vol.111 , pp. 4632-4637
    • Feng, Z.1    Mao, Y.2    Xu, N.3    Zhang, B.4    Wei, P.5    Yang, D.-L.6
  • 26
    • 84885181396 scopus 로고    scopus 로고
    • Efficient genome editing in plants using a CRISPR/Cas system
    • Feng, Z., Zhang, B., Ding, W., Liu, X., Yang, D.-L., Wei, P., et al. (2013). Efficient genome editing in plants using a CRISPR/Cas system. Cell Res. 23, 1229-1232. doi: 10. 1038/cr. 2013. 114
    • (2013) Cell Res , vol.23 , pp. 1229-1232
    • Feng, Z.1    Zhang, B.2    Ding, W.3    Liu, X.4    Yang, D.-L.5    Wei, P.6
  • 27
    • 84896405585 scopus 로고    scopus 로고
    • Precision genetic modifications: A new era in molecular biology and crop improvement
    • Fichtner, F., Urrea Castellanos, R., and Ülker, B. (2014). Precision genetic modifications: a new era in molecular biology and crop improvement. Planta 239, 921-939. doi: 10. 1007/s00425-014-2029-y
    • (2014) Planta , vol.239 , pp. 921-939
    • Fichtner, F.1    Urrea Castellanos, R.2    Ülker, B.3
  • 28
    • 84896929630 scopus 로고    scopus 로고
    • Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
    • Fu, Y., Sander, J. D., Reyon, D., Cascio, V. M., and Joung, J. K. (2014). Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nat. Biotechnol. 32, 279-284. doi: 10. 1038/nbt. 2808
    • (2014) Nat. Biotechnol , vol.32 , pp. 279-284
    • Fu, Y.1    Sander, J.D.2    Reyon, D.3    Cascio, V.M.4    Joung, J.K.5
  • 29
    • 84879264708 scopus 로고    scopus 로고
    • ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
    • Gaj, T., Gersbach, C. A., and Barbas, C. F. (2013). ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol. 31, 397-405. doi: 10. 1016/j. tibtech. 2013. 04. 004
    • (2013) Trends Biotechnol , vol.31 , pp. 397-405
    • Gaj, T.1    Gersbach, C.A.2    Barbas, C.F.3
  • 30
    • 84919838986 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated targeted mutagenesis in Nicotiana tabacum
    • Gao, J., Wang, G., Ma, S., Xie, X., Wu, X., Zhang, X., et al. (2014). CRISPR/Cas9-mediated targeted mutagenesis in Nicotiana tabacum. Plant Mol. Biol. 87, 99-110. doi: 10. 1007/s11103-014-0263-0
    • (2014) Plant Mol. Biol , vol.87 , pp. 99-110
    • Gao, J.1    Wang, G.2    Ma, S.3    Xie, X.4    Wu, X.5    Zhang, X.6
  • 31
    • 84897546295 scopus 로고    scopus 로고
    • Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing
    • Gao, Y., and Zhao, Y. (2014a). Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing. J. Integr. Plant Biol. 56, 343-349. doi: 10. 1111/jipb. 12152
    • (2014) J. Integr. Plant Biol , vol.56 , pp. 343-349
    • Gao, Y.1    Zhao, Y.2
  • 32
    • 84896950755 scopus 로고    scopus 로고
    • Specific and heritable gene editing in Arabidopsis
    • Gao, Y., and Zhao, Y. (2014b). Specific and heritable gene editing in Arabidopsis. Proc. Natl. Acad. Sci. U. S. A. 111, 4357-4358. doi: 10. 1073/pnas. 1402295111
    • (2014) Proc. Natl. Acad. Sci. U. S. A , vol.111 , pp. 4357-4358
    • Gao, Y.1    Zhao, Y.2
  • 34
    • 84908352138 scopus 로고    scopus 로고
    • Genome-scale CRISPR-mediated control of gene repression and activation
    • Gilbert, L. A., Horlbeck, M. A., Adamson, B., Villalta, J. E., Chen, Y., Whitehead, E. H., et al. (2015). Genome-scale CRISPR-mediated control of gene repression and activation. Cell 159, 647-661. doi: 10. 1016/j. cell. 2014. 09. 029
    • (2015) Cell , vol.159 , pp. 647-661
    • Gilbert, L.A.1    Horlbeck, M.A.2    Adamson, B.3    Villalta, J.E.4    Chen, Y.5    Whitehead, E.H.6
  • 35
    • 84880571335 scopus 로고    scopus 로고
    • CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
    • Gilbert, L. A., Larson, M. H., Morsut, L., Liu, Z., Brar, G. A., Torres, S. E., et al. (2013). CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154, 442-451. doi: 10. 1016/j. cell. 2013. 06. 044
    • (2013) Cell , vol.154 , pp. 442-451
    • Gilbert, L.A.1    Larson, M.H.2    Morsut, L.3    Liu, Z.4    Brar, G.A.5    Torres, S.E.6
  • 36
    • 84901594468 scopus 로고    scopus 로고
    • Precise plant breeding using new genome editing techniques: Opportunities, safety and regulation in the EU
    • Hartung, F., and Schiemann, J. (2014). Precise plant breeding using new genome editing techniques: opportunities, safety and regulation in the EU. Plant J. 78, 742-752. doi: 10. 1111/tpj. 12413
    • (2014) Plant J , vol.78 , pp. 742-752
    • Hartung, F.1    Schiemann, J.2
  • 37
    • 84885398906 scopus 로고    scopus 로고
    • A CRISPR/Cas for high-throughput silencing
    • Heintze, J., Luft, C., and Ketteler, R. (2013). A CRISPR/Cas for high-throughput silencing. Front. Genet. 4: 193. doi: 10. 3389/fgene. 2013. 00193
    • (2013) Front. Genet , vol.4 , pp. 193
    • Heintze, J.1    Luft, C.2    Ketteler, R.3
  • 38
    • 84910126816 scopus 로고    scopus 로고
    • Progress of cereal transformation technology mediated by Agrobacterium tumefaciens
    • Hiei, Y., Ishida, Y., and Komari, T. (2014). Progress of cereal transformation technology mediated by Agrobacterium tumefaciens. Front. Plant Sci. 5: 628. doi: 10. 3389/fpls. 2014. 00628
    • (2014) Front. Plant Sci , vol.5 , pp. 628
    • Hiei, Y.1    Ishida, Y.2    Komari, T.3
  • 39
    • 79958243028 scopus 로고    scopus 로고
    • Environmental risk assessment of genetically modified plants-concepts and controversies
    • Hilbeck, A., Meier, M., Römbke, J., Jänsch, S., Teichmann, H., and Tappeser, B. (2011). Environmental risk assessment of genetically modified plants-concepts and controversies. Environ. Sci. Eur. 23, 1-12. doi: 10. 1186/2190-4715-23-13
    • (2011) Environ. Sci. Eur , vol.23 , pp. 1-12
    • Hilbeck, A.1    Meier, M.2    Römbke, J.3    Jänsch, S.4    Teichmann, H.5    Tappeser, B.6
  • 40
    • 84920435758 scopus 로고    scopus 로고
    • Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles
    • Hyun, Y., Kim, J., Cho, S. W., Choi, Y., Kim, J.-S., and Coupland, G. (2015). Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles. Planta 241, 271-284. doi: 10. 1007/s00425-014-2180-5
    • (2015) Planta , vol.241 , pp. 271-284
    • Hyun, Y.1    Kim, J.2    Cho, S.W.3    Choi, Y.4    Kim, J.-S.5    Coupland, G.6
  • 41
    • 84944937432 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening
    • Ito, Y., Nishizawa-Yokoi, A., Endo, M., Mikami, M., and Toki, S. (2015). CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening. Biochem. Biophy. Res. Commun. 467, 76-82. doi: 10. 1016/j. bbrc. 2015. 09. 117
    • (2015) Biochem. Biophy. Res. Commun , vol.467 , pp. 76-82
    • Ito, Y.1    Nishizawa-Yokoi, A.2    Endo, M.3    Mikami, M.4    Toki, S.5
  • 42
    • 84928261737 scopus 로고    scopus 로고
    • Targeted genome modifications in soybean with CRISPR/Cas9
    • Jacobs, T. B., LaFayette, P. R., Schmitz, R. J., and Parrott, W. A. (2015). Targeted genome modifications in soybean with CRISPR/Cas9. BMC Biotechnol. 15: 16. doi: 10. 1186/s12896-015-0131-2
    • (2015) BMC Biotechnol , vol.15 , pp. 16
    • Jacobs, T.B.1    LaFayette, P.R.2    Schmitz, R.J.3    Parrott, W.A.4
  • 43
    • 84934878723 scopus 로고    scopus 로고
    • Function genomics of abiotic stress tolerance in plants: A CRISPR approach
    • Jain, M. (2015). Function genomics of abiotic stress tolerance in plants: a CRISPR approach. Front. Plant Sci. 6: 375. doi: 10. 3389/fpls. 2015. 00375
    • (2015) Front. Plant Sci , vol.6 , pp. 375
    • Jain, M.1
  • 44
    • 84947775797 scopus 로고    scopus 로고
    • Establishing a CRISPR-Cas-like immune system conferring DNA virus resistance in plants
    • Ji, X., Zhang, H., Zhang, Y., Wang, Y., and Gao, C. (2015). Establishing a CRISPR-Cas-like immune system conferring DNA virus resistance in plants. Nat. Plants 1, 15144. doi: 10. 1038/nplants. 2015. 144
    • (2015) Nat. Plants , vol.1
    • Ji, X.1    Zhang, H.2    Zhang, Y.3    Wang, Y.4    Gao, C.5
  • 45
    • 84899556051 scopus 로고    scopus 로고
    • Targeted genome editing of sweet orange using Cas9/sgRNA
    • Jia, H., and Wang, N. (2014). Targeted genome editing of sweet orange using Cas9/sgRNA. PLoS ONE 9: e93806. doi: 10. 1371/journal. pone. 0093806
    • (2014) PLoS ONE , vol.9
    • Jia, H.1    Wang, N.2
  • 46
    • 84903398817 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-mediated gene editing in Arabidopsis thaliana and inheritance of modified genes in the T2 and T3 generations
    • Jiang, W., Yang, B., and Weeks, D. P. (2014). Efficient CRISPR/Cas9-mediated gene editing in Arabidopsis thaliana and inheritance of modified genes in the T2 and T3 generations. PLoS ONE 9: e99225. doi: 10. 1371/journal. pone. 0099225
    • (2014) PLoS ONE , vol.9
    • Jiang, W.1    Yang, B.2    Weeks, D.P.3
  • 47
    • 84886926151 scopus 로고    scopus 로고
    • Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice
    • Jiang, W., Zhou, H., Bi, H., Fromm, M., Yang, B., and Weeks, D. P. (2013). Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice. Nucleic Acids Res. 41: e188. doi: 10. 1093/nar/gkt780
    • (2013) Nucleic Acids Res , vol.41
    • Jiang, W.1    Zhou, H.2    Bi, H.3    Fromm, M.4    Yang, B.5    Weeks, D.P.6
  • 48
    • 84876567971 scopus 로고    scopus 로고
    • RNA-programmed genome editing in human cells
    • Jinek, M., East, A., Cheng, A., and Li, S. (2013). RNA-programmed genome editing in human cells. Elife 2: e00471. doi: 10. 7554/eLife. 00471
    • (2013) Elife , vol.2
    • Jinek, M.1    East, A.2    Cheng, A.3    Li, S.4
  • 49
    • 84893157352 scopus 로고    scopus 로고
    • Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
    • Jinek, M., Jiang, F., Taylor, D. W., Sternberg, S. H., Kaya, E., Ma, E., et al. (2014). Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science 343: 1247997. doi: 10. 1126/science. 1247997
    • (2014) Science , vol.343
    • Jinek, M.1    Jiang, F.2    Taylor, D.W.3    Sternberg, S.H.4    Kaya, E.5    Ma, E.6
  • 50
    • 85027948074 scopus 로고    scopus 로고
    • Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta
    • Johnson, R. A., Gurevich, V., Filler, S., Samach, A., and Levy, A. (2015). Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta. Plant Mol. Biol. 87, 143-156. doi: 10. 1007/s11103-014-0266-x
    • (2015) Plant Mol. Biol , vol.87 , pp. 143-156
    • Johnson, R.A.1    Gurevich, V.2    Filler, S.3    Samach, A.4    Levy, A.5
  • 51
    • 84928825287 scopus 로고    scopus 로고
    • Regulatory uncertainty over genome editing
    • Jones, H. D. (2015). Regulatory uncertainty over genome editing. Nat Plants 1, 14011. doi: 10. 1038/nplants. 2014. 11
    • (2015) Nat Plants , vol.1
    • Jones, H.D.1
  • 53
    • 84964198529 scopus 로고    scopus 로고
    • Development and characterization of transgenic chickpea (Cicer arietinum L.) plants with cry1Ac gene using tissue culture independent protocol
    • Khatodia, S., Kharb, P., Batra, P., and Chowdhury, V. K. (2014). Development and characterization of transgenic chickpea (Cicer arietinum L.) plants with cry1Ac gene using tissue culture independent protocol. Int. J. Adv. Res. 2, 323-331.
    • (2014) Int. J. Adv. Res , vol.2 , pp. 323-331
    • Khatodia, S.1    Kharb, P.2    Batra, P.3    Chowdhury, V.K.4
  • 54
    • 84964205879 scopus 로고    scopus 로고
    • Trending: The Cas nuclease mediated genome editing technique
    • Khatodia, S., and Khurana, S. M. P. (2014). Trending: the Cas nuclease mediated genome editing technique. Biotech Today 4, 46-49. doi: 10. 5958/2322-0996. 2014. 00019. 2
    • (2014) Biotech Today , vol.4 , pp. 46-49
    • Khatodia, S.1    Khurana, S.M.P.2
  • 55
    • 84898778301 scopus 로고    scopus 로고
    • A guide to genome engineering with programmable nucleases
    • Kim, H., and Kim, J. S. (2014). A guide to genome engineering with programmable nucleases. Nat. Rev. Genet. 15, 321-334. doi: 10. 1038/nrg3686
    • (2014) Nat. Rev. Genet , vol.15 , pp. 321-334
    • Kim, H.1    Kim, J.S.2
  • 56
    • 84902299964 scopus 로고    scopus 로고
    • Enhancing crop resilience to combined abiotic and biotic stress through the dissection of physiological and molecular crosstalk
    • Kissoudis, C., van de Wiel, C., Visser, R. G. F., and van der Linden, G. (2014). Enhancing crop resilience to combined abiotic and biotic stress through the dissection of physiological and molecular crosstalk. Front. Plant Sci. 5: 207. doi: 10. 3389/fpls. 2014. 00207
    • (2014) Front. Plant Sci , vol.5 , pp. 207
    • Kissoudis, C.1    van de Wiel, C.2    Visser, R.G.F.3    van der Linden, G.4
  • 57
    • 84922522034 scopus 로고    scopus 로고
    • The CRISPR-Cas system for plant genome editing: Advances and opportunities
    • Kumar, V., and Jain, M. (2014). The CRISPR-Cas system for plant genome editing: advances and opportunities. J. Exp. Bot. 66, 47-57. doi: 10. 1093/jxb/eru429
    • (2014) J. Exp. Bot , vol.66 , pp. 47-57
    • Kumar, V.1    Jain, M.2
  • 58
    • 84929000302 scopus 로고    scopus 로고
    • The genome of cultivated sweet potato contains Agrobacterium T-DNAs with expressed genes: An example of a naturally transgenic food crop
    • Kyndt, T., Quispe, D., Zhai, H., Jarret, R., Ghislain, M., Liu, Q., et al. (2015). The genome of cultivated sweet potato contains Agrobacterium T-DNAs with expressed genes: an example of a naturally transgenic food crop. Proc. Natl. Acad. Sci. U. S. A. 112, 5844-5849. doi: 10. 1073/pnas. 1419685112
    • (2015) Proc. Natl. Acad. Sci. U. S. A , vol.112 , pp. 5844-5849
    • Kyndt, T.1    Quispe, D.2    Zhai, H.3    Jarret, R.4    Ghislain, M.5    Liu, Q.6
  • 59
    • 84929701098 scopus 로고    scopus 로고
    • Synthetic RNAs for gene regulation: Design principles and computational tools
    • Laganà, A., Shasha, D., and Croce, C. M. (2014). Synthetic RNAs for gene regulation: design principles and computational tools. Front. Bioeng. Biotechnol. 2: 65. doi: 10. 3389/fbioe. 2014. 00065
    • (2014) Front. Bioeng. Biotechnol , vol.2 , pp. 65
    • Laganà, A.1    Shasha, D.2    Croce, C.M.3
  • 60
    • 84886993480 scopus 로고    scopus 로고
    • CRISPR interference (CRISPRi) for sequence-specific control of gene expression
    • Larson, M. H., Gilbert, L. A., Wang, X., Lim, W. A., Weissman, J. S., and Qi, L. S. (2013). CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat. Protoc. 8, 2180-2196. doi: 10. 1038/nprot. 2013. 132
    • (2013) Nat. Protoc , vol.8 , pp. 2180-2196
    • Larson, M.H.1    Gilbert, L.A.2    Wang, X.3    Lim, W.A.4    Weissman, J.S.5    Qi, L.S.6
  • 61
    • 84903312241 scopus 로고    scopus 로고
    • Key applications of plant metabolic engineering
    • Lau, W., Fischbach, M. A., Osbourn, A., and Sattely, E. S. (2014). Key applications of plant metabolic engineering. PLoS Biol. 12: e1001879. doi: 10. 1371/journal. pbio. 1001879
    • (2014) PLoS Biol , vol.12
    • Lau, W.1    Fischbach, M.A.2    Osbourn, A.3    Sattely, E.S.4
  • 62
    • 84883785822 scopus 로고    scopus 로고
    • Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
    • Li, J. F., Norville, J. E., Aach, J., McCormack, M., Zhang, D., Bush, J., et al. (2013). Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat. Biotechnol. 31, 688-691. doi: 10. 1038/nbt. 2654
    • (2013) Nat. Biotechnol , vol.31 , pp. 688-691
    • Li, J.F.1    Norville, J.E.2    Aach, J.3    McCormack, M.4    Zhang, D.5    Bush, J.6
  • 63
    • 84953342474 scopus 로고    scopus 로고
    • The molecular mechanism of CRISPR/Cas9 system and its application in gene therapy of human diseases
    • Liang, Q., Huashan, L., Yunhan, J., and Chunsheng, D. (2015). The molecular mechanism of CRISPR/Cas9 system and its application in gene therapy of human diseases. Yi Chuan 37, 974-982. doi: 10. 16288/j. yczz. 15-109
    • (2015) Yi Chuan , vol.37 , pp. 974-982
    • Liang, Q.1    Huashan, L.2    Yunhan, J.3    Chunsheng, D.4
  • 64
    • 84894321885 scopus 로고    scopus 로고
    • Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system
    • Liang, Z., Zhang, K., Chen, K., and Gao, C. (2014). Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system. J. Genet. Genomics 41, 63-68. doi: 10. 1016/j. jgg. 2013. 12. 001
    • (2014) J. Genet. Genomics , vol.41 , pp. 63-68
    • Liang, Z.1    Zhang, K.2    Chen, K.3    Gao, C.4
  • 65
    • 84900852939 scopus 로고    scopus 로고
    • CRISPR-Cas system: A powerful tool for genome engineering
    • Liu, L., and Fan, X. D. (2014). CRISPR-Cas system: a powerful tool for genome engineering. Plant Mol. Biol. 85, 209-218. doi: 10. 1007/s11103-014-0188-7
    • (2014) Plant Mol. Biol , vol.85 , pp. 209-218
    • Liu, L.1    Fan, X.D.2
  • 66
    • 84886092842 scopus 로고    scopus 로고
    • Advanced genetic tools for plant biotechnology
    • Liu, W., Yuan, J. S., and Stewart, C. N. (2013). Advanced genetic tools for plant biotechnology. Nat. Rev. Genet. 14, 781-793. doi: 10. 1038/nrg3583
    • (2013) Nat. Rev. Genet , vol.14 , pp. 781-793
    • Liu, W.1    Yuan, J.S.2    Stewart, C.N.3
  • 67
    • 84942931752 scopus 로고    scopus 로고
    • A CRISPR/Cas9 toolbox for multiplexed plant genome editing and transcriptional regulation
    • Lowder, L. G., Zhang, D., Baltes, N. J., Paul, J. W. III, Tang, X., Zheng, X., et al. (2015). A CRISPR/Cas9 toolbox for multiplexed plant genome editing and transcriptional regulation. Plant Physiol. 169, 971-985. doi: 10. 1104/pp. 15. 00636
    • (2015) Plant Physiol , vol.169 , pp. 971-985
    • Lowder, L.G.1    Zhang, D.2    Baltes, N.J.3    Paul, J.W.4    Tang, X.5    Zheng, X.6
  • 68
    • 84899929404 scopus 로고    scopus 로고
    • Plant genome engineering in full bloom
    • Lozano-Juste, J., and Cutler, S. R. (2014). Plant genome engineering in full bloom. Trends Plant Sci. 19, 284-287. doi: 10. 1016/j. tplants. 2014. 02. 014
    • (2014) Trends Plant Sci , vol.19 , pp. 284-287
    • Lozano-Juste, J.1    Cutler, S.R.2
  • 69
    • 84857925027 scopus 로고    scopus 로고
    • Deployment of new biotechnologies in plant breeding
    • Lusser, M., Parisi, C., Plan, D., and Rodríguez-Cerezo, E. (2012). Deployment of new biotechnologies in plant breeding. Nat. Biotechnol. 30, 231-239. doi: 10. 1038/nbt. 2142
    • (2012) Nat. Biotechnol , vol.30 , pp. 231-239
    • Lusser, M.1    Parisi, C.2    Plan, D.3    Rodríguez-Cerezo, E.4
  • 70
    • 84938748218 scopus 로고    scopus 로고
    • A robust CRISPR/Cas9 system for convenient, high-efficiency multiplex genome editing in monocot and dicot plants
    • Ma, X., Zhang, Q., Zhu, Q., Liu, W., Chen, Y., Qiu, R., et al. (2015). A robust CRISPR/Cas9 system for convenient, high-efficiency multiplex genome editing in monocot and dicot plants. Mol. Plant 8, 1274-1284. doi: 10. 1016/j. molp. 2015. 04. 007
    • (2015) Mol. Plant , vol.8 , pp. 1274-1284
    • Ma, X.1    Zhang, Q.2    Zhu, Q.3    Liu, W.4    Chen, Y.5    Qiu, R.6
  • 72
    • 84921467997 scopus 로고    scopus 로고
    • Genome engineering via TALENs and CRISPR/Cas9 systems: Challenges and perspectives
    • Mahfouz, M. M., Piatek, A., and Stewart, C. N. (2014). Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives. Plant Biotechnol. J. 12, 1006-1014. doi: 10. 1111/pbi. 12256
    • (2014) Plant Biotechnol. J , vol.12 , pp. 1006-1014
    • Mahfouz, M.M.1    Piatek, A.2    Stewart, C.N.3
  • 73
    • 84884160273 scopus 로고    scopus 로고
    • CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
    • Mali, P., Aach, J., Stranges, P. B., Esvelt, K. M., Moosburner, M., Kosuri, S., et al. (2013). CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol. 31, 833-838. doi: 10. 1038/nbt. 2675
    • (2013) Nat. Biotechnol , vol.31 , pp. 833-838
    • Mali, P.1    Aach, J.2    Stranges, P.B.3    Esvelt, K.M.4    Moosburner, M.5    Kosuri, S.6
  • 74
    • 84891932593 scopus 로고    scopus 로고
    • Application of the CRISPR-Cas system for efficient genome engineering in plants
    • Mao, Y., Zhang, H., Xu, N., Zhang, B., Gou, F., and Zhu, J.-K. (2013). Application of the CRISPR-Cas system for efficient genome engineering in plants. Mol. Plant 6, 2008-2011. doi: 10. 1093/mp/sst121
    • (2013) Mol. Plant , vol.6 , pp. 2008-2011
    • Mao, Y.1    Zhang, H.2    Xu, N.3    Zhang, B.4    Gou, F.5    Zhu, J.-K.6
  • 75
    • 84885180177 scopus 로고    scopus 로고
    • Targeted mutagenesis in rice using CRISPR-Cas system
    • Miao, J., Guo, D., Zhang, J., Huang, Q., Qin, G., Zhang, X., et al. (2013). Targeted mutagenesis in rice using CRISPR-Cas system. Cell Res. 23, 1233-1236. doi: 10. 1038/cr. 2013. 123
    • (2013) Cell Res , vol.23 , pp. 1233-1236
    • Miao, J.1    Guo, D.2    Zhang, J.3    Huang, Q.4    Qin, G.5    Zhang, X.6
  • 76
    • 85013017478 scopus 로고    scopus 로고
    • CRISPR/Cas mutagenesis of soybean and Medicago truncatula using a new web-tool and a modified Cas9 enzyme
    • Michno, J. M., Wang, X., Liu, J., Curtin, S. J., Kono, T. J., and Stupar, R. M. (2015). CRISPR/Cas mutagenesis of soybean and Medicago truncatula using a new web-tool and a modified Cas9 enzyme. GM Crops Food 6, 243-252. doi: 10. 1080/21645698. 2015. 1106063
    • (2015) GM Crops Food , vol.6 , pp. 243-252
    • Michno, J.M.1    Wang, X.2    Liu, J.3    Curtin, S.J.4    Kono, T.J.5    Stupar, R.M.6
  • 77
    • 84883828590 scopus 로고    scopus 로고
    • Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
    • Nekrasov, V., Staskawicz, B., Weigel, D., Jones, J. D. G., and Kamoun, S. (2013). Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31, 691-693. doi: 10. 1038/nbt. 2655
    • (2013) Nat. Biotechnol , vol.31 , pp. 691-693
    • Nekrasov, V.1    Staskawicz, B.2    Weigel, D.3    Jones, J.D.G.4    Kamoun, S.5
  • 78
    • 84914671859 scopus 로고    scopus 로고
    • Plant-Agrobacterium interaction mediated by ethylene and super-Agrobacterium conferring efficient gene transfer
    • Nonaka, S., and Ezura, H. (2014). Plant-Agrobacterium interaction mediated by ethylene and super-Agrobacterium conferring efficient gene transfer. Front. Plant Sci. 5: 681. doi: 10. 3389/fpls. 2014. 00681
    • (2014) Front. Plant Sci , vol.5 , pp. 681
    • Nonaka, S.1    Ezura, H.2
  • 79
    • 84938521400 scopus 로고    scopus 로고
    • Genome editing with engineered nucleases in plants
    • Osakabe, Y., and Osakabe, K. (2015). Genome editing with engineered nucleases in plants. Plant Cell Physiol. 56, 389-400. doi: 10. 1093/pcp/pcu170
    • (2015) Plant Cell Physiol , vol.56 , pp. 389-400
    • Osakabe, Y.1    Osakabe, K.2
  • 80
    • 84928212884 scopus 로고    scopus 로고
    • RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors
    • Piatek, A., Ali, Z., Baazim, H., Li, L., Abulfaraj, A., Al-Shareef, S., et al. (2014). RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors. Plant Biotechnol. J. 13, 578-589. doi: 10. 1111/pbi. 12284
    • (2014) Plant Biotechnol. J , vol.13 , pp. 578-589
    • Piatek, A.1    Ali, Z.2    Baazim, H.3    Li, L.4    Abulfaraj, A.5    Al-Shareef, S.6
  • 81
    • 84870601200 scopus 로고    scopus 로고
    • Transgenic or not? No simple answer! New biotechnology-based plant breeding techniques and the regulatory landscape
    • Podevin, N., Devos, Y., Davies, H. V., and Nielsen, K. M. (2012). Transgenic or not? No simple answer! New biotechnology-based plant breeding techniques and the regulatory landscape. EMBO Rep. 13, 1057-1061. doi: 10. 1038/embor. 2012. 168
    • (2012) EMBO Rep , vol.13 , pp. 1057-1061
    • Podevin, N.1    Devos, Y.2    Davies, H.V.3    Nielsen, K.M.4
  • 82
    • 84925534357 scopus 로고    scopus 로고
    • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation
    • Polstein, L. R., and Gersbach, C. A. (2015). A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nat. Chem. Biol. 11, 198-200. doi: 10. 1038/nchembio. 1753
    • (2015) Nat. Chem. Biol , vol.11 , pp. 198-200
    • Polstein, L.R.1    Gersbach, C.A.2
  • 83
    • 85027953332 scopus 로고    scopus 로고
    • Using CRISPR/Cas in three dimensions: Towards synthetic plant genomes, transcriptomes and epigenomes
    • [Epub ahead of print]
    • Puchta, H. (2016). Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes. Plant J. doi: 10. 1111/tpj. 13100 [Epub ahead of print].
    • (2016) Plant J
    • Puchta, H.1
  • 84
    • 84874687019 scopus 로고    scopus 로고
    • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
    • Qi, L. S., Larson, M. H., Gilbert, L. A., Doudna, J. A., Weissman, J. S., Arkin, A. P., et al. (2013). Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152, 1173-1183. doi: 10. 1016/j. cell. 2013. 02. 022
    • (2013) Cell , vol.152 , pp. 1173-1183
    • Qi, L.S.1    Larson, M.H.2    Gilbert, L.A.3    Doudna, J.A.4    Weissman, J.S.5    Arkin, A.P.6
  • 85
    • 84947024957 scopus 로고    scopus 로고
    • The CRISPR-Cas9 technology: Closer to the ultimate toolkit for targeted genome editing
    • Quétier, F. (2016). The CRISPR-Cas9 technology: closer to the ultimate toolkit for targeted genome editing. Plant Sci. 242, 65-76. doi: 10. 1016/j. plantsci. 2015. 09. 003
    • (2016) Plant Sci , vol.242 , pp. 65-76
    • Quétier, F.1
  • 86
    • 84901843996 scopus 로고    scopus 로고
    • Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
    • Ramakrishna, S., Kwaku Dad, A. B., Beloor, J., Gopalappa, R., Lee, S. K., and Kim, H. (2014). Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA. Genome Res. 24, 1020-1027. doi: 10. 1101/gr. 171264. 113
    • (2014) Genome Res , vol.24 , pp. 1020-1027
    • Ramakrishna, S.1    Kwaku Dad, A.B.2    Beloor, J.3    Gopalappa, R.4    Lee, S.K.5    Kim, H.6
  • 87
    • 84884288934 scopus 로고    scopus 로고
    • Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
    • Ran, F. A., Hsu, P. D., Lin, C.-Y., Gootenberg, J. S., Konermann, S., Trevino, A. E., et al. (2013). Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154, 1380-1389. doi: 10. 1016/j. cell. 2013. 08. 021
    • (2013) Cell , vol.154 , pp. 1380-1389
    • Ran, F.A.1    Hsu, P.D.2    Lin, C.-Y.3    Gootenberg, J.S.4    Konermann, S.5    Trevino, A.E.6
  • 88
    • 84907731269 scopus 로고    scopus 로고
    • Hairy root transformation using Agrobacterium rhizogenes as a tool for exploring cell type-specific gene expression and function using tomato as a model
    • Ron, M., Kajala, K., Pauluzzi, G., Wang, D., Reynoso, M. A., Zumstein, K., et al. (2014). Hairy root transformation using Agrobacterium rhizogenes as a tool for exploring cell type-specific gene expression and function using tomato as a model. Plant Physiol. 166, 455-469. doi: 10. 1104/pp. 114. 239392
    • (2014) Plant Physiol , vol.166 , pp. 455-469
    • Ron, M.1    Kajala, K.2    Pauluzzi, G.3    Wang, D.4    Reynoso, M.A.5    Zumstein, K.6
  • 89
    • 84908015428 scopus 로고    scopus 로고
    • The non-homologous end-joining pathway is involved in stable transformation in rice
    • Saika, H., Nishizawa-Yokoi, A., and Toki, S. (2014). The non-homologous end-joining pathway is involved in stable transformation in rice. Front. Plant Sci. 5: 560. doi: 10. 3389/fpls. 2014. 00560
    • (2014) Front. Plant Sci , vol.5 , pp. 560
    • Saika, H.1    Nishizawa-Yokoi, A.2    Toki, S.3
  • 90
    • 84900314611 scopus 로고    scopus 로고
    • CRISPR-Cas systems for editing, regulating and targeting genomes
    • Sander, J. D., and Joung, J. K. (2014). CRISPR-Cas systems for editing, regulating and targeting genomes. Nat. Biotechnol. 32, 347-355. doi: 10. 1038/nbt. 2842
    • (2014) Nat. Biotechnol , vol.32 , pp. 347-355
    • Sander, J.D.1    Joung, J.K.2
  • 91
    • 84957656529 scopus 로고    scopus 로고
    • Opportunities for products of new plant breeding techniques
    • [Epub ahead of print]
    • Schaart, J. G., van de Wiel, C. C. M., Lotz, L. A. P., and Smulders, M. J. M. (2015). Opportunities for products of new plant breeding techniques. Trends Plant Sci. doi: 10. 1016/j. tplants. 2015. 11. 006 [Epub ahead of print].
    • (2015) Trends Plant Sci
    • Schaart, J.G.1    van de Wiel, C.C.M.2    Lotz, L.A.P.3    Smulders, M.J.M.4
  • 92
    • 84916624400 scopus 로고    scopus 로고
    • The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny
    • Schiml, S., Fauser, F., and Puchta, H. (2014). The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny. Plant J. 80, 1139-1150. doi: 10. 1111/tpj. 12704
    • (2014) Plant J , vol.80 , pp. 1139-1150
    • Schiml, S.1    Fauser, F.2    Puchta, H.3
  • 93
    • 85042815594 scopus 로고    scopus 로고
    • Targeted genome modification of crop plants using a CRISPR-Cas system
    • Shan, Q., Wang, Y., Li, J., Zhang, Y., Chen, K., Liang, Z., et al. (2013). Targeted genome modification of crop plants using a CRISPR-Cas system. Nat. Biotechnol. 31, 686-688. doi: 10. 1038/nbt. 2650
    • (2013) Nat. Biotechnol , vol.31 , pp. 686-688
    • Shan, Q.1    Wang, Y.2    Li, J.3    Zhang, Y.4    Chen, K.5    Liang, Z.6
  • 94
    • 84922264247 scopus 로고    scopus 로고
    • Positive-negative-selection-mediated gene targeting in rice
    • Shimatani, Z., Nishizawa-Yokoi, A., Endo, M., Toki, S., and Terada, R. (2015). Positive-negative-selection-mediated gene targeting in rice. Front. Plant Sci. 5: 748. doi: 10. 3389/fpls. 2014. 00748
    • (2015) Front. Plant Sci , vol.5 , pp. 748
    • Shimatani, Z.1    Nishizawa-Yokoi, A.2    Endo, M.3    Toki, S.4    Terada, R.5
  • 95
    • 35348890199 scopus 로고    scopus 로고
    • Bacterial DNA repair by non-homologous end joining
    • Shuman, S., and Glickman, M. S. (2007). Bacterial DNA repair by non-homologous end joining. Nat. Rev. Microbiol. 5, 852-861. doi: 10. 1038/nrmicro1768
    • (2007) Nat. Rev. Microbiol , vol.5 , pp. 852-861
    • Shuman, S.1    Glickman, M.S.2
  • 96
    • 84899120939 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated targeted mutagenesis in the liverwort Marchantia polymorpha L
    • Sugano, S. S., Shirakawa, M., Takagi, J., Matsuda, Y., Shimada, T., Hara-Nishimura, I., et al. (2014). CRISPR/Cas9-mediated targeted mutagenesis in the liverwort Marchantia polymorpha L. Plant Cell Physiol. 55, 475-481. doi: 10. 1093/pcp/pcu014
    • (2014) Plant Cell Physiol , vol.55 , pp. 475-481
    • Sugano, S.S.1    Shirakawa, M.2    Takagi, J.3    Matsuda, Y.4    Shimada, T.5    Hara-Nishimura, I.6
  • 97
    • 84930651072 scopus 로고    scopus 로고
    • Targeted mutagenesis in soybean using the CRISPR-Cas9 system
    • Sun, X., Hu, Z., Chen, R., Jiang, Q., Song, G., Zhang, H., et al. (2015). Targeted mutagenesis in soybean using the CRISPR-Cas9 system. Sci. Rep. 5, 10342. doi: 10. 1038/srep10342
    • (2015) Sci. Rep , vol.5
    • Sun, X.1    Hu, Z.2    Chen, R.3    Jiang, Q.4    Song, G.5    Zhang, H.6
  • 98
    • 84942901283 scopus 로고    scopus 로고
    • Targeted mutagenesis, precise gene editing, and site-specific gene insertion in maize using Cas9 and guide RNA
    • Svitashev, S., Young, J. K., Schwartz, C., Gao, H., Falco, S. C., and Cigan, A. M. (2015). Targeted mutagenesis, precise gene editing, and site-specific gene insertion in maize using Cas9 and guide RNA. Plant Physiol. 169, 931-945. doi: 10. 1104/pp. 15. 00793
    • (2015) Plant Physiol , vol.169 , pp. 931-945
    • Svitashev, S.1    Young, J.K.2    Schwartz, C.3    Gao, H.4    Falco, S.C.5    Cigan, A.M.6
  • 99
    • 84908328232 scopus 로고    scopus 로고
    • A protein-tagging system for signal amplification in gene expression and fluorescence imaging
    • Tanenbaum, M. E., Gilbert, L. A., Qi, L. S., Weissman, J. S., and Vale, R. D. (2014). A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell 159, 635-646. doi: 10. 1016/j. cell. 2014. 09. 039
    • (2014) Cell , vol.159 , pp. 635-646
    • Tanenbaum, M.E.1    Gilbert, L.A.2    Qi, L.S.3    Weissman, J.S.4    Vale, R.D.5
  • 100
    • 84953344352 scopus 로고    scopus 로고
    • Highly efficient CRISPR/Cas9-mediated targeted mutagenesis of multiple genes in Populus
    • Tingting, L., Di, F., Lingyu, R., Yuanzhong, J., Rui, L., and Keming, L. (2015). Highly efficient CRISPR/Cas9-mediated targeted mutagenesis of multiple genes in Populus. Yi Chuan 37, 1044-1052. doi: 10. 16288/j. yczz. 15-303
    • (2015) Yi Chuan , vol.37 , pp. 1044-1052
    • Tingting, L.1    Di, F.2    Lingyu, R.3    Yuanzhong, J.4    Rui, L.5    Keming, L.6
  • 101
    • 84902204289 scopus 로고    scopus 로고
    • Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
    • Tsai, S. Q., Wyvekens, N., Khayter, C., Foden, J. A., Thapar, V., Reyon, D., et al. (2014). Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Nat. Biotechnol. 32, 569-576. doi: 10. 1038/nbt. 2908
    • (2014) Nat. Biotechnol , vol.32 , pp. 569-576
    • Tsai, S.Q.1    Wyvekens, N.2    Khayter, C.3    Foden, J.A.4    Thapar, V.5    Reyon, D.6
  • 102
    • 84890831873 scopus 로고    scopus 로고
    • RNA-guided genome editing for target gene mutations in wheat
    • Upadhyay, S. K., Kumar, J., Alok, A., and Tuli, R. (2013). RNA-guided genome editing for target gene mutations in wheat. G3 (Bethesda) 3, 2233-2238. doi: 10. 1534/g3. 113. 008847
    • (2013) G3 (Bethesda) , vol.3 , pp. 2233-2238
    • Upadhyay, S.K.1    Kumar, J.2    Alok, A.3    Tuli, R.4
  • 103
    • 84903317244 scopus 로고    scopus 로고
    • Precision genome engineering and agriculture: Opportunities and regulatory challenges
    • Voytas, D. F., and Gao, C. (2014). Precision genome engineering and agriculture: opportunities and regulatory challenges. PLoS Biol. 12: e1001877. doi: 10. 1371/journal. pbio. 1001877
    • (2014) PLoS Biol , vol.12
    • Voytas, D.F.1    Gao, C.2
  • 104
    • 84938988571 scopus 로고    scopus 로고
    • Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system
    • Wang, S., Zhang, S., Wang, W., Xiong, X., Meng, F., and Cui, X. (2015). Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system. Plant Cell Rep. 34, 1473-1476. doi: 10. 1007/s00299-015-1816-7
    • (2015) Plant Cell Rep , vol.34 , pp. 1473-1476
    • Wang, S.1    Zhang, S.2    Wang, W.3    Xiong, X.4    Meng, F.5    Cui, X.6
  • 105
    • 84921934205 scopus 로고    scopus 로고
    • Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
    • Wang, Y., Cheng, X., Shan, Q., Zhang, Y., Liu, J., Gao, C., et al. (2014). Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nat. Biotechnol. 32, 947-951. doi: 10. 1038/nbt. 2969
    • (2014) Nat. Biotechnol , vol.32 , pp. 947-951
    • Wang, Y.1    Cheng, X.2    Shan, Q.3    Zhang, Y.4    Liu, J.5    Gao, C.6
  • 106
    • 84938709908 scopus 로고    scopus 로고
    • The regulatory status of genome-edited crops
    • Wolt, J. D., Wang, K., and Yang, B. (2015). The regulatory status of genome-edited crops. Plant Biotechnol. J. 14, 510-518. doi: 10. 1111/pbi. 12444
    • (2015) Plant Biotechnol. J , vol.14 , pp. 510-518
    • Wolt, J.D.1    Wang, K.2    Yang, B.3
  • 107
    • 84947255513 scopus 로고    scopus 로고
    • DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
    • Woo, J. W., Kim, J., Kwon, S. I., Corvalan, C., Cho, S. W., Kim, H., et al. (2015). DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins. Nat. Biotechnol. 33, 1162-1164. doi: 10. 1038/nbt. 3389
    • (2015) Nat. Biotechnol , vol.33 , pp. 1162-1164
    • Woo, J.W.1    Kim, J.2    Kwon, S.I.3    Corvalan, C.4    Cho, S.W.5    Kim, H.6
  • 108
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: All's well that ends well
    • Wyman, C., and Kanaar, R. (2006). DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40, 363-383. doi: 10. 1146/annurev. genet. 40. 110405. 090451
    • (2006) Annu. Rev. Genet , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 109
    • 84925262435 scopus 로고    scopus 로고
    • Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system
    • Xie, K., Minkenberg, B., and Yang, Y. (2015). Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system. Proc. Natl. Acad. Sci. U. S. A. 112, 3570-3575. doi: 10. 1073/pnas. 1420294112
    • (2015) Proc. Natl. Acad. Sci. U. S. A , vol.112 , pp. 3570-3575
    • Xie, K.1    Minkenberg, B.2    Yang, Y.3
  • 110
    • 84884962826 scopus 로고    scopus 로고
    • RNA-guided genome editing in plants using a CRISPR-Cas system
    • Xie, K., and Yang, Y. (2013). RNA-guided genome editing in plants using a CRISPR-Cas system. Mol. Plant 6, 1975-1983. doi: 10. 1093/mp/sst119
    • (2013) Mol. Plant , vol.6 , pp. 1975-1983
    • Xie, K.1    Yang, Y.2
  • 111
    • 84964313841 scopus 로고    scopus 로고
    • A CRISPR/Cas9 toolkit for multiplex genome editing in plants
    • Xing, H.-L., Dong, L., Wang, Z.-P., Zhang, H.-Y., Han, C.-Y., Liu, B., et al. (2014). A CRISPR/Cas9 toolkit for multiplex genome editing in plants. BMC Plant Biol. 14: 327. doi: 10. 1186/s12870-014-0327-y
    • (2014) BMC Plant Biol , vol.14 , pp. 327
    • Xing, H.-L.1    Dong, L.2    Wang, Z.-P.3    Zhang, H.-Y.4    Han, C.-Y.5    Liu, B.6
  • 112
    • 84935033103 scopus 로고    scopus 로고
    • Generation of inheritable and "transgene clean" targeted genome-modified rice in later generations using the CRISPR/Cas9 system
    • Xu, R. F., Li, H., Qin, R. Y., Li, J., Qiu, C. H., Yang, Y. C., et al. (2015). Generation of inheritable and "transgene clean" targeted genome-modified rice in later generations using the CRISPR/Cas9 system. Sci. Rep. 5, 11491. doi: 10. 1038/srep11491
    • (2015) Sci. Rep , vol.5
    • Xu, R.F.1    Li, H.2    Qin, R.Y.3    Li, J.4    Qiu, C.H.5    Yang, Y.C.6
  • 113
    • 84894081804 scopus 로고    scopus 로고
    • Cas9-based tools for targeted genome editing and transcriptional control
    • Xu, T., Li, Y., Van Nostrand, J. D., He, Z., and Zhou, J. (2014). Cas9-based tools for targeted genome editing and transcriptional control. Appl. Environ. Microbiol. 80, 1544-1552. doi: 10. 1128/AEM. 03786-13
    • (2014) Appl. Environ. Microbiol , vol.80 , pp. 1544-1552
    • Xu, T.1    Li, Y.2    Van Nostrand, J.D.3    He, Z.4    Zhou, J.5
  • 114
    • 84943602335 scopus 로고    scopus 로고
    • A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing
    • Yin, K., Han, T., Liu, G., Chen, T., Wang, Y., Yu, A. Y., et al. (2015). A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing. Sci. Rep. 5, 14926. doi: 10. 1038/srep14926
    • (2015) Sci. Rep , vol.5
    • Yin, K.1    Han, T.2    Liu, G.3    Chen, T.4    Wang, Y.5    Yu, A.Y.6
  • 115
    • 84923297110 scopus 로고    scopus 로고
    • A split-Cas9 architecture for inducible genome editing and transcription modulation
    • Zetsche, B., Volz, S. E., and Zhang, F. (2015). A split-Cas9 architecture for inducible genome editing and transcription modulation. Nat. Biotechnol. 33, 139-142. doi: 10. 1038/nbt. 3149
    • (2015) Nat. Biotechnol , vol.33 , pp. 139-142
    • Zetsche, B.1    Volz, S.E.2    Zhang, F.3
  • 116
    • 84904639258 scopus 로고    scopus 로고
    • The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation
    • Zhang, H., Zhang, J., Wei, P., Zhang, B., Gou, F., Feng, Z., et al. (2014). The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation. Plant Biotechnol. J. 12, 797-807. doi: 10. 1111/pbi. 12200
    • (2014) Plant Biotechnol. J , vol.12 , pp. 797-807
    • Zhang, H.1    Zhang, J.2    Wei, P.3    Zhang, B.4    Gou, F.5    Feng, Z.6
  • 117
    • 84902002231 scopus 로고    scopus 로고
    • CRISPR/Cas technology: A revolutionary approach for genome engineering
    • Zhang, L., and Zhou, Q. (2014). CRISPR/Cas technology: a revolutionary approach for genome engineering. Sci. China Life Sci. 57, 639-640. doi: 10. 1007/s11427-014-4670-x
    • (2014) Sci. China Life Sci , vol.57 , pp. 639-640
    • Zhang, L.1    Zhou, Q.2
  • 118
    • 84949557262 scopus 로고    scopus 로고
    • A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis
    • Zhang, Z., Mao, Y., Ha, S., Liu, W., Botella, J. R., and Zhu, J. K. (2015). A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis. Plant Cell Rep. 1-5. doi: 10. 1007/s00299-015-1900-z
    • (2015) Plant Cell Rep , pp. 1-5
    • Zhang, Z.1    Mao, Y.2    Ha, S.3    Liu, W.4    Botella, J.R.5    Zhu, J.K.6
  • 119
    • 84921549293 scopus 로고    scopus 로고
    • Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice
    • Zhou, H., Liu, B., Weeks, D. P., Spalding, M. H., and Yang, B. (2014). Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice. Nucleic Acids Res. 42, 10903-10914. doi: 10. 1093/nar/gku806
    • (2014) Nucleic Acids Res , vol.42 , pp. 10903-10914
    • Zhou, H.1    Liu, B.2    Weeks, D.P.3    Spalding, M.H.4    Yang, B.5
  • 120
    • 84942827085 scopus 로고    scopus 로고
    • Exploiting SNPs for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4-coumarate: CoA ligase specificity and redundancy
    • Zhou, X., Jacobs, T. B., Xue, L.-J., Harding, S. A., and Tsai, C. J. (2015). Exploiting SNPs for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4-coumarate: CoA ligase specificity and redundancy. New Phytol. 208, 298-301. doi: 10. 1111/nph. 13470
    • (2015) New Phytol , vol.208 , pp. 298-301
    • Zhou, X.1    Jacobs, T.B.2    Xue, L.-J.3    Harding, S.A.4    Tsai, C.J.5


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