-
1
-
-
84864920004
-
Comparison of next-generation sequencing systems
-
251364
-
Liu L, Li Y, Li S, Hu N, He Y, Pong R, Lin D, Lu L, Law M. 2012. Comparison of next-generation sequencing systems. J. Biomed. Biotechnol. 2012:251364. http://dx.doi.org/10.1155/2012/251364.
-
(2012)
J. Biomed. Biotechnol.
, vol.2012
-
-
Liu, L.1
Li, Y.2
Li, S.3
Hu, N.4
He, Y.5
Pong, R.6
Lin, D.7
Lu, L.8
Law, M.9
-
2
-
-
84873800970
-
Genome-scale engineering for systems and synthetic biology
-
Esvelt KM, Wang HH. 2013. Genome-scale engineering for systems and synthetic biology. Mol. Syst. Biol. 9:641. http://dx.doi.org/10.1038/msb.2012.66.
-
(2013)
Mol. Syst. Biol.
, vol.9
, pp. 641
-
-
Esvelt, K.M.1
Wang, H.H.2
-
3
-
-
84879264708
-
ZFN, TALEN, and CRISPR/Casbased methods for genome engineering
-
Gaj T, Gersbach CA, Barbas CF. 2013. ZFN, TALEN, and CRISPR/Casbased methods for genome engineering. Trends Biotechnol. 31:397-405. http://dx.doi.org/10.1016/j.tibtech.2013.04.004.
-
(2013)
Trends Biotechnol.
, vol.31
, pp. 397-405
-
-
Gaj, T.1
Gersbach, C.A.2
Barbas, C.F.3
-
4
-
-
77249170201
-
CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea
-
Marraffini LA, Sontheimer EJ. 2010. CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea. Nat. Rev. Genet. 11:181-190. http://dx.doi.org/10.1038/nrg2749.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 181-190
-
-
Marraffini, L.A.1
Sontheimer, E.J.2
-
5
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. 2012. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337:816-821. http://dx.doi.org/10.1126/science.1225829.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
6
-
-
84866983297
-
A CRISPR approach to gene targeting
-
Carroll D. 2012. A CRISPR approach to gene targeting. Mol. Ther. 20: 1658-1660. http://dx.doi.org/10.1038/mt.2012.171.
-
(2012)
Mol. Ther.
, vol.20
, pp. 1658-1660
-
-
Carroll, D.1
-
7
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
-
Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, Jaenisch R. 2013. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154:1370-1379. http://dx.doi.org/10.1016/j.cell.2013.08.022.
-
(2013)
Cell
, vol.154
, pp. 1370-1379
-
-
Yang, H.1
Wang, H.2
Shivalila, C.S.3
Cheng, A.W.4
Shi, L.5
Jaenisch, R.6
-
8
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang HY, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. 2013. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153: 910-918. http://dx.doi.org/10.1016/j.cell.2013.04.025.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.Y.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
9
-
-
84884288934
-
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
-
Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. 2013. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154:1380-1389. http://dx.doi.org/10.1016/j.cell.2013.08.021.
-
(2013)
Cell
, vol.154
, pp. 1380-1389
-
-
Ran, F.A.1
Hsu, P.D.2
Lin, C.Y.3
Gootenberg, J.S.4
Konermann, S.5
Trevino, A.E.6
Scott, D.A.7
Inoue, A.8
Matoba, S.9
Zhang, Y.10
Zhang, F.11
-
10
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. 2013. RNA-guided human genome engineering via Cas9. Science 339:823-826. http://dx.doi.org/10.1126/science.1232033.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
11
-
-
84884160273
-
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
-
Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM. 2013. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol. 31:833-838. http://dx.doi.org/10.1038/nbt.2675.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 833-838
-
-
Mali, P.1
Aach, J.2
Stranges, P.B.3
Esvelt, K.M.4
Moosburner, M.5
Kosuri, S.6
Yang, L.7
Church, G.M.8
-
12
-
-
84883785822
-
Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guideRNAand Cas9
-
Li JF, Norville JE, Aach J, McCormack M, Zhang D, Bush J, Church GM, Sheen J. 2013. Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guideRNAand Cas9. Nat. Biotechnol. 31:688-691. http://dx.doi.org/10.1038/nbt.2654.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 688-691
-
-
Li, J.F.1
Norville, J.E.2
Aach, J.3
McCormack, M.4
Zhang, D.5
Bush, J.6
Church, G.M.7
Sheen, J.8
-
13
-
-
84874608929
-
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
-
Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA. 2013. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat. Biotechnol. 31:233-239. http://dx.doi.org/10.1038/nbt.2508.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 233-239
-
-
Jiang, W.1
Bikard, D.2
Cox, D.3
Zhang, F.4
Marraffini, L.A.5
-
14
-
-
84876575031
-
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
-
DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM. 2013. Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Res. 41:4336-4343. http://dx.doi.org/10.1093/nar/gkt135.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 4336-4343
-
-
DiCarlo, J.E.1
Norville, J.E.2
Mali, P.3
Rios, X.4
Aach, J.5
Church, G.M.6
-
15
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho SW, Kim S, Kim JM, Kim JS. 2013. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31:230-232. http://dx.doi.org/10.1038/nbt.2507.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.S.4
-
16
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. 2013. Multiplex genome engineering using CRISPR/Cas systems. Science 339:819-823. http://dx.doi.org/10.1126/science.1231143.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
17
-
-
84874687019
-
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
-
Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. 2013. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152:1173-1183. http://dx.doi.org/10.1016/j.cell.2013.02.022.
-
(2013)
Cell
, vol.152
, pp. 1173-1183
-
-
Qi, L.S.1
Larson, M.H.2
Gilbert, L.A.3
Doudna, J.A.4
Weissman, J.S.5
Arkin, A.P.6
Lim, W.A.7
-
18
-
-
84880571335
-
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
-
Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. 2013. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154:442-451. http://dx.doi.org/10.1016/j.cell.2013.06.044.
-
(2013)
Cell
, vol.154
, pp. 442-451
-
-
Gilbert, L.A.1
Larson, M.H.2
Morsut, L.3
Liu, Z.4
Brar, G.A.5
Torres, S.E.6
Stern-Ginossar, N.7
Brandman, O.8
Whitehead, E.H.9
Doudna, J.A.10
Lim, W.A.11
Weissman, J.S.12
Qi, L.S.13
-
19
-
-
84882986957
-
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
-
Bikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA. 2013. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res. 41: 7429-7437. http://dx.doi.org/10.1093/nar/gkt520.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 7429-7437
-
-
Bikard, D.1
Jiang, W.2
Samai, P.3
Hochschild, A.4
Zhang, F.5
Marraffini, L.A.6
-
20
-
-
0034923498
-
Design and selection of novel Cys(2)His(2) zinc finger proteins
-
Pabo CO, Peisach E, Grant RA. 2001. Design and selection of novel Cys(2)His(2) zinc finger proteins. Annu. Rev. Biochem. 70:313-340. http://dx.doi.org/10.1146/annurev.biochem.70.1.313.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 313-340
-
-
Pabo, C.O.1
Peisach, E.2
Grant, R.A.3
-
21
-
-
84865513069
-
TALE nucleases: tailored genome engineering made easy
-
Mussolino C, Cathomen T. 2012. TALE nucleases: tailored genome engineering made easy. Curr. Opin. Biotechnol. 23:644-650. http://dx.doi.org/10.1016/j.copbio.2012.01.013.
-
(2012)
Curr. Opin. Biotechnol.
, vol.23
, pp. 644-650
-
-
Mussolino, C.1
Cathomen, T.2
-
22
-
-
74249095519
-
CRISPR/Cas, the immune system of bacteria and archaea
-
Horvath P, Barrangou R. 2010. CRISPR/Cas, the immune system of bacteria and archaea. Science 327:167-170. http://dx.doi.org/10.1126/science.1179555.
-
(2010)
Science
, vol.327
, pp. 167-170
-
-
Horvath, P.1
Barrangou, R.2
-
23
-
-
79960554003
-
Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems
-
Makarova KS, Aravind L, Wolf YI, Koonin EV. 2011. Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems. Biol. Direct 6:38. http://dx.doi.org/10.1186/1745-6150-6-38.
-
(2011)
Biol. Direct
, vol.6
, pp. 38
-
-
Makarova, K.S.1
Aravind, L.2
Wolf, Y.I.3
Koonin, E.V.4
-
24
-
-
79956157571
-
Evolution and classification of the CRISPR-Cas systems
-
Makarova KS, Haft DH, Barrangou R, Brouns SJ, Charpentier E, Horvath P, Moineau S, Mojica FJ, Wolf YI, Yakunin AF, van der Oost J, Koonin EV. 2011 Evolution and classification of the CRISPR-Cas systems. Nat. Rev. Microbiol. 9:467-477. http://dx.doi.org/10.1038/nrmicro2577.
-
(2011)
Nat. Rev. Microbiol.
, vol.9
, pp. 467-477
-
-
Makarova, K.S.1
Haft, D.H.2
Barrangou, R.3
Brouns, S.J.4
Charpentier, E.5
Horvath, P.6
Moineau, S.7
Mojica, F.J.8
Wolf, Y.I.9
Yakunin, A.F.10
van der Oost, J.11
Koonin, E.V.12
-
25
-
-
84873571066
-
In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus
-
Sinkunas T, Gasiunas G, Waghmare SP, Dickman MJ, Barrangou R, Horvath P, Siksnys V. 2013. In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus. EMBO J. 32:385-394. http://dx.doi.org/10.1038/emboj.2012.352.
-
(2013)
EMBO J.
, vol.32
, pp. 385-394
-
-
Sinkunas, T.1
Gasiunas, G.2
Waghmare, S.P.3
Dickman, M.J.4
Barrangou, R.5
Horvath, P.6
Siksnys, V.7
-
26
-
-
84856778250
-
Structure and mechanism of the CMR complex for CRISPRmediated antiviral immunity
-
Zhang J, Rouillon C, Kerou M, Reeks J, Brugger K, Graham S, Reimann J, Cannone G, Liu H, Albers SV, Naismith JH, Spagnolo L, White MF. 2012. Structure and mechanism of the CMR complex for CRISPRmediated antiviral immunity. Mol. Cell 45:303-313. http://dx.doi.org/10.1016/j.molcel.2011.12.013.
-
(2012)
Mol. Cell
, vol.45
, pp. 303-313
-
-
Zhang, J.1
Rouillon, C.2
Kerou, M.3
Reeks, J.4
Brugger, K.5
Graham, S.6
Reimann, J.7
Cannone, G.8
Liu, H.9
Albers, S.V.10
Naismith, J.H.11
Spagnolo, L.12
White, M.F.13
-
27
-
-
79953250082
-
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
-
Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E. 2011. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471:602-607. http://dx.doi.org/10.1038/nature09886.
-
(2011)
Nature
, vol.471
, pp. 602-607
-
-
Deltcheva, E.1
Chylinski, K.2
Sharma, C.M.3
Gonzales, K.4
Chao, Y.5
Pirzada, Z.A.6
Eckert, M.R.7
Vogel, J.8
Charpentier, E.9
-
28
-
-
80755145195
-
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
-
Sapranauskas R, Gasiunas G, Fremaux C, Barrangou R, Horvath P, Siksnys V. 2011. The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli. Nucleic Acids Res. 39:9275-9282. http://dx.doi.org/10.1093/nar/gkr606.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 9275-9282
-
-
Sapranauskas, R.1
Gasiunas, G.2
Fremaux, C.3
Barrangou, R.4
Horvath, P.5
Siksnys, V.6
-
29
-
-
84866859751
-
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
-
Gasiunas G, Barrangou R, Horvath P, Siksnys V. 2012. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. U. S. A. 109:E2579-E2586. http://dx.doi.org/10.1073/pnas.1208507109.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
-
-
Gasiunas, G.1
Barrangou, R.2
Horvath, P.3
Siksnys, V.4
-
30
-
-
84878193178
-
Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis
-
Zhang Y, Heidrich N, Ampattu BJ, Gunderson CW, Seifert HS, Schoen C, Vogel J, Sontheimer EJ. 2013. Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis. Mol. Cell 50:488-503. http://dx.doi.org/10.1016/j.molcel.2013.05.001.
-
(2013)
Mol. Cell
, vol.50
, pp. 488-503
-
-
Zhang, Y.1
Heidrich, N.2
Ampattu, B.J.3
Gunderson, C.W.4
Seifert, H.S.5
Schoen, C.6
Vogel, J.7
Sontheimer, E.J.8
-
31
-
-
84887104139
-
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
-
Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. 2013. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nat. Methods 10:1116-1121. http://dx.doi.org/10.1038/nmeth.2681.
-
(2013)
Nat. Methods
, vol.10
, pp. 1116-1121
-
-
Esvelt, K.M.1
Mali, P.2
Braff, J.L.3
Moosburner, M.4
Yaung, S.J.5
Church, G.M.6
-
32
-
-
67650756698
-
Analysis of CRISPR in Streptococcus mutans suggests frequent occurrence of acquired immunity against infection by M102-like bacteriophages
-
van der Ploeg JR. 2009. Analysis of CRISPR in Streptococcus mutans suggests frequent occurrence of acquired immunity against infection by M102-like bacteriophages. Microbiology 155:1966-1976. http://dx.doi.org/10.1099/mic.0.027508-0.
-
(2009)
Microbiology
, vol.155
, pp. 1966-1976
-
-
van der Ploeg, J.R.1
-
33
-
-
38949123143
-
Phage response to CRISPRencoded resistance in Streptococcus thermophilus
-
Deveau H, Barrangou R, Garneau JE, Labonte J, Fremaux C, Boyaval P, Romero DA, Horvath P, Moineau S. 2008. Phage response to CRISPRencoded resistance in Streptococcus thermophilus. J. Bacteriol. 190:1390-1400. http://dx.doi.org/10.1128/JB.01412-07.
-
(2008)
J. Bacteriol.
, vol.190
, pp. 1390-1400
-
-
Deveau, H.1
Barrangou, R.2
Garneau, J.E.3
Labonte, J.4
Fremaux, C.5
Boyaval, P.6
Romero, D.A.7
Horvath, P.8
Moineau, S.9
-
34
-
-
80755187812
-
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation
-
Bhaya D, Davison M, Barrangou R. 2011. CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation. Annu. Rev. Genet. 45:273-297. http://dx.doi.org/10.1146/annurev-genet-110410-132430.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 273-297
-
-
Bhaya, D.1
Davison, M.2
Barrangou, R.3
-
35
-
-
84879016248
-
crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
-
Karvelis T, Gasiunas G, Miksys A, Barrangou R, Horvath P, Siksnys V. 2013. crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus. RNA Biol. 10:841-851. http://dx.doi.org/10.4161/rna.24203.
-
(2013)
RNA Biol.
, vol.10
, pp. 841-851
-
-
Karvelis, T.1
Gasiunas, G.2
Miksys, A.3
Barrangou, R.4
Horvath, P.5
Siksnys, V.6
-
36
-
-
84878211288
-
The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
-
Chylinski K, Le Rhun A, Charpentier E. 2013. The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems. RNA Biol. 10:726-737. http://dx.doi.org/10.4161/rna.24321.
-
(2013)
RNA Biol.
, vol.10
, pp. 726-737
-
-
Chylinski, K.1
Le Rhun, A.2
Charpentier, E.3
-
37
-
-
84878936806
-
CRISPR-mediated adaptive immune systems in bacteria and archaea
-
Sorek R, Lawrence CM, Wiedenheft B. 2013. CRISPR-mediated adaptive immune systems in bacteria and archaea. Annu. Rev. Biochem. 82:237-266. http://dx.doi.org/10.1146/annurev-biochem-072911-172315.
-
(2013)
Annu. Rev. Biochem.
, vol.82
, pp. 237-266
-
-
Sorek, R.1
Lawrence, C.M.2
Wiedenheft, B.3
-
38
-
-
84884962826
-
RNA-guided genome editing in plants using a CRISPR-Cas system
-
Xie K, Yang Y. 2013. RNA-guided genome editing in plants using a CRISPR-Cas system. Mol. Plant 6:1975-1983. http://dx.doi.org/10.1093/mp/sst119.
-
(2013)
Mol. Plant
, vol.6
, pp. 1975-1983
-
-
Xie, K.1
Yang, Y.2
-
39
-
-
84877103949
-
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
-
Shen B, Zhang J, Wu H, Wang J, Ma K, Li Z, Zhang X, Zhang P, Huang X. 2013. Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 23:720-723. http://dx.doi.org/10.1038/cr.2013.46.
-
(2013)
Cell Res.
, vol.23
, pp. 720-723
-
-
Shen, B.1
Zhang, J.2
Wu, H.3
Wang, J.4
Ma, K.5
Li, Z.6
Zhang, X.7
Zhang, P.8
Huang, X.9
-
40
-
-
84874617789
-
Efficient genome editing in zebrafish using a CRISPR-Cas system
-
Hwang WY, Fu YF, Reyon D, Maeder ML, Tsai SQ, Sander JD, Peterson RT, Yeh JRJ, Joung JK. 2013. Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31:227-229. http://dx.doi.org/10.1038/nbt.2501.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 227-229
-
-
Hwang, W.Y.1
Fu, Y.F.2
Reyon, D.3
Maeder, M.L.4
Tsai, S.Q.5
Sander, J.D.6
Peterson, R.T.7
Yeh, J.R.J.8
Joung, J.K.9
-
41
-
-
84880088705
-
Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease
-
Gratz SJ, Cummings AM, Nguyen JN, Hamm DC, Donohue LK, Harrison MM, Wildonger J, O'Connor-Giles KM. 2013. Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease. Genetics 113:152710. http://dx.doi.org/10.1534/genetics.113.152710.
-
(2013)
Genetics
, vol.113
, pp. 152710
-
-
Gratz, S.J.1
Cummings, A.M.2
Nguyen, J.N.3
Hamm, D.C.4
Donohue, L.K.5
Harrison, M.M.6
Wildonger, J.7
O'Connor-Giles, K.M.8
-
42
-
-
84876409836
-
Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos
-
Chang N, Sun C, Gao L, Zhu D, Xu X, Zhu X, Xiong JW, Xi JJ. 2013. Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos. Cell Res. 23:465-472. http://dx.doi.org/10.1038/cr.2013.45.
-
(2013)
Cell Res.
, vol.23
, pp. 465-472
-
-
Chang, N.1
Sun, C.2
Gao, L.3
Zhu, D.4
Xu, X.5
Zhu, X.6
Xiong, J.W.7
Xi, J.J.8
-
43
-
-
33845604556
-
DNA double-strand break repair: all's well that ends well
-
Wyman C, Kanaar R. 2006. DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40:363-383. http://dx.doi.org/10.1146/annurev.genet.40.110405.090451.
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
44
-
-
35348890199
-
Bacterial DNA repair by nonhomologous end joining
-
Shuman S, Glickman MS. 2007. Bacterial DNA repair by nonhomologous end joining. Nat. Rev. Microbiol. 5:852-861. http://dx.doi.org/10.1038/nrmicro1768.
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 852-861
-
-
Shuman, S.1
Glickman, M.S.2
-
45
-
-
0035671854
-
Homologous recombination near and far from DNA breaks: alternative roles and contrasting views
-
Smith GR. 2001. Homologous recombination near and far from DNA breaks: alternative roles and contrasting views. Annu. Rev. Genet. 35:243-274. http://dx.doi.org/10.1146/annurev.genet.35.102401.090509.
-
(2001)
Annu. Rev. Genet.
, vol.35
, pp. 243-274
-
-
Smith, G.R.1
-
46
-
-
84886926151
-
Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice
-
Jiang W, Zhou H, Bi H, Fromm M, Yang B, Weeks DP. 2013. Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice. Nucleic Acids Res. 41:e188. http://dx.doi.org/10.1093/nar/gkt780.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Jiang, W.1
Zhou, H.2
Bi, H.3
Fromm, M.4
Yang, B.5
Weeks, D.P.6
-
47
-
-
84883828590
-
Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
-
Nekrasov V, Staskawicz B, Weigel D, Jones JD, Kamoun S. 2013. Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31:691-693. http://dx.doi.org/10.1038/nbt.2655.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 691-693
-
-
Nekrasov, V.1
Staskawicz, B.2
Weigel, D.3
Jones, J.D.4
Kamoun, S.5
-
48
-
-
85042815594
-
Targeted genome modification of crop plants using a CRISPR-Cas system
-
Shan Q, Wang Y, Li J, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi JJ, Qiu JL, Gao C. 2013. Targeted genome modification of crop plants using a CRISPR-Cas system. Nat. Biotechnol. 31:686-688. http://dx.doi.org/10.1038/nbt.2650.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 686-688
-
-
Shan, Q.1
Wang, Y.2
Li, J.3
Zhang, Y.4
Chen, K.5
Liang, Z.6
Zhang, K.7
Liu, J.8
Xi, J.J.9
Qiu, J.L.10
Gao, C.11
-
49
-
-
84884904381
-
Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination
-
Dickinson DJ, Ward JD, Reiner DJ, Goldstein B. 2013. Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. Nat. Methods 10:1028-1034. http://dx.doi.org/10.1038/nmeth.2641.
-
(2013)
Nat. Methods
, vol.10
, pp. 1028-1034
-
-
Dickinson, D.J.1
Ward, J.D.2
Reiner, D.J.3
Goldstein, B.4
-
50
-
-
84876016461
-
Mammalian base excision repair: the forgotten archangel
-
Dianov GL, Hubscher U. 2013. Mammalian base excision repair: the forgotten archangel. Nucleic Acids Res. 41:3483-3490. http://dx.doi.org/10.1093/nar/gkt076.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 3483-3490
-
-
Dianov, G.L.1
Hubscher, U.2
-
51
-
-
84877766936
-
Molecular mechanisms of RNA interference
-
Wilson RC, Doudna JA. 2013. Molecular mechanisms of RNA interference. Annu. Rev. Biophys. 42:217-239. http://dx.doi.org/10.1146/annurev-biophys-083012-130404.
-
(2013)
Annu. Rev. Biophys.
, vol.42
, pp. 217-239
-
-
Wilson, R.C.1
Doudna, J.A.2
-
52
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller JC, Tan SY, Qiao GJ, Barlow KA, Wang JB, Xia DF, Meng XD, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ. 2011. A TALE nuclease architecture for efficient genome editing. Nat. Biotechnol. 29:143-148. http://dx.doi.org/10.1038/nbt.1755.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.Y.2
Qiao, G.J.3
Barlow, K.A.4
Wang, J.B.5
Xia, D.F.6
Meng, X.D.7
Paschon, D.E.8
Leung, E.9
Hinkley, S.J.10
Dulay, G.P.11
Hua, K.L.12
Ankoudinova, I.13
Cost, G.J.14
Urnov, F.D.15
Zhang, H.S.16
Holmes, M.C.17
Zhang, L.18
Gregory, P.D.19
Rebar, E.J.20
more..
-
53
-
-
33845916259
-
Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase
-
Minczuk M, Papworth MA, Kolasinska P, Murphy MP, Klug A. 2006. Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase. Proc. Natl. Acad. Sci. U. S. A. 103:19689-19694. http://dx.doi.org/10.1073/pnas.0609502103.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 19689-19694
-
-
Minczuk, M.1
Papworth, M.A.2
Kolasinska, P.3
Murphy, M.P.4
Klug, A.5
-
54
-
-
33846686888
-
Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes
-
Li FY, Papworth M, Minczuk M, Rohde C, Zhang YY, Ragozin S, Jeltsch A. 2007. Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes. Nucleic Acids Res. 35:100-112. http://dx.doi.org/10.1093/nar/gkl1035.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 100-112
-
-
Li, F.Y.1
Papworth, M.2
Minczuk, M.3
Rohde, C.4
Zhang, Y.Y.5
Ragozin, S.6
Jeltsch, A.7
-
55
-
-
84884856342
-
Cas9 as a versatile tool for engineering biology
-
Mali P, Esvelt KM, Church GM. 2013. Cas9 as a versatile tool for engineering biology. Nat. Methods 10:957-963. http://dx.doi.org/10.1038/nmeth.2649.
-
(2013)
Nat. Methods
, vol.10
, pp. 957-963
-
-
Mali, P.1
Esvelt, K.M.2
Church, G.M.3
-
56
-
-
84886993480
-
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
-
Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. 2013. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat. Protoc. 8:2180-2196. http://dx.doi.org/10.1038/nprot.2013.132.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2180-2196
-
-
Larson, M.H.1
Gilbert, L.A.2
Wang, X.3
Lim, W.A.4
Weissman, J.S.5
Qi, L.S.6
-
57
-
-
84892765883
-
Genome-scale CRISPR-Cas9 knockout screening in human cells
-
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelson T, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. 2013. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343:84-87. http://dx.doi.org/10.1126/science.1247005.
-
(2013)
Science
, vol.343
, pp. 84-87
-
-
Shalem, O.1
Sanjana, N.E.2
Hartenian, E.3
Shi, X.4
Scott, D.A.5
Mikkelson, T.6
Heckl, D.7
Ebert, B.L.8
Root, D.E.9
Doench, J.G.10
Zhang, F.11
-
58
-
-
84892749369
-
Genetic screens in human cells using the CRISPR/Cas9 system
-
Wang T, Wei JJ, Sabatini DM, Lander ES. 2013. Genetic screens in human cells using the CRISPR/Cas9 system. Science 343:80-84. http://dx.doi.org/10.1126/science.1246981.
-
(2013)
Science
, vol.343
, pp. 80-84
-
-
Wang, T.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
59
-
-
84876567971
-
RNAprogrammed genome editing in human cells
-
Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J. 2013. RNAprogrammed genome editing in human cells. eLife 2:e00471. doi:http://dx.doi.org/10.7554/eLife.00471.
-
(2013)
eLife
, vol.2
-
-
Jinek, M.1
East, A.2
Cheng, A.3
Lin, S.4
Ma, E.5
Doudna, J.6
-
60
-
-
84890787845
-
Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis
-
Nakayama T, Fish MB, Fisher M, Oomen-Hajagos J, Thomsen GH, Grainger RM. 2013. Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis. Genesis 51:835-843. http://dx.doi.org/10.1002/dvg.22720.
-
(2013)
Genesis
, vol.51
, pp. 835-843
-
-
Nakayama, T.1
Fish, M.B.2
Fisher, M.3
Oomen-Hajagos, J.4
Thomsen, G.H.5
Grainger, R.M.6
-
61
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD. 2013. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 31:822-826. http://dx.doi.org/10.1038/nbt.2623.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
Joung, J.K.6
Sander, J.D.7
-
62
-
-
84885180177
-
Targeted mutagenesis in rice using CRISPR-Cas system
-
Miao J, Guo D, Zhang J, Huang Q, Qin G, Zhang X, Wan J, Gu H, Qu LJ. 2013. Targeted mutagenesis in rice using CRISPR-Cas system. Cell Res. 23:1233-1236. http://dx.doi.org/10.1038/cr.2013.123.
-
(2013)
Cell Res.
, vol.23
, pp. 1233-1236
-
-
Miao, J.1
Guo, D.2
Zhang, J.3
Huang, Q.4
Qin, G.5
Zhang, X.6
Wan, J.7
Gu, H.8
Qu, L.J.9
-
63
-
-
79959963663
-
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
-
Semenova E, Jore MM, Datsenko KA, Semenova A, Westra ER, Wanner B, van der Oost J, Brouns SJ, Severinov K. 2011. Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence. Proc. Natl. Acad. Sci. U. S. A. 108:10098-10103. http://dx.doi.org/10.1073/pnas.1104144108.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 10098-10103
-
-
Semenova, E.1
Jore, M.M.2
Datsenko, K.A.3
Semenova, A.4
Westra, E.R.5
Wanner, B.6
van der Oost, J.7
Brouns, S.J.8
Severinov, K.9
-
64
-
-
79751538119
-
Recombinase technology: applications and possibilities
-
Wang Y, Yau YY, Perkins-Balding D, Thomson JG. 2011. Recombinase technology: applications and possibilities. Plant Cell Rep. 30:267-285. http://dx.doi.org/10.1007/s00299-010-0938-1.
-
(2011)
Plant Cell Rep.
, vol.30
, pp. 267-285
-
-
Wang, Y.1
Yau, Y.Y.2
Perkins-Balding, D.3
Thomson, J.G.4
-
65
-
-
1542397137
-
Phage integrases: biology and applications
-
Groth AC, Calos MP. 2004. Phage integrases: biology and applications. J. Mol. Biol. 335:667-678. http://dx.doi.org/10.1016/j.jmb.2003.09.082.
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 667-678
-
-
Groth, A.C.1
Calos, M.P.2
-
66
-
-
77955867185
-
Genome editing with engineered zinc finger nucleases
-
Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD. 2010. Genome editing with engineered zinc finger nucleases. Nat. Rev. Genet. 11:636-646. http://dx.doi.org/10.1038/nrg2842.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 636-646
-
-
Urnov, F.D.1
Rebar, E.J.2
Holmes, M.C.3
Zhang, H.S.4
Gregory, P.D.5
-
68
-
-
84877323295
-
Off-target effect of endogenous siRNA derived from RMRP in human cells
-
Maida Y, Kyo S, Lassmann T, Hayashizaki Y, Masutomi K. 2013. Off-target effect of endogenous siRNA derived from RMRP in human cells. Int. J. Mol. Sci. 14:9305-9318. http://dx.doi.org/10.3390/ijms14059305.
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 9305-9318
-
-
Maida, Y.1
Kyo, S.2
Lassmann, T.3
Hayashizaki, Y.4
Masutomi, K.5
-
69
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. 2003. Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21:635-637. http://dx.doi.org/10.1038/nbt831.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
70
-
-
84884930591
-
CRISPR/Cas9-targeted mutagenesis in Caenorhabditis elegans
-
Waaijers S, Portegijs V, Kerver J, Lemmens BB, Tijsterman M, van den Heuvel S, Boxem M. 2013. CRISPR/Cas9-targeted mutagenesis in Caenorhabditis elegans. Genetics 195:1187-1191. http://dx.doi.org/10.1534/genetics.113.156299.
-
(2013)
Genetics
, vol.195
, pp. 1187-1191
-
-
Waaijers, S.1
Portegijs, V.2
Kerver, J.3
Lemmens, B.B.4
Tijsterman, M.5
van den Heuvel, S.6
Boxem, M.7
-
71
-
-
80053039555
-
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
-
Mussolino C, Morbitzer R, Lutge F, Dannemann N, Lahaye T, Cathomen T. 2011. A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Nucleic Acids Res. 39: 9283-9293. http://dx.doi.org/10.1093/nar/gkr597.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 9283-9293
-
-
Mussolino, C.1
Morbitzer, R.2
Lutge, F.3
Dannemann, N.4
Lahaye, T.5
Cathomen, T.6
|