Lactate promotes glutamine uptake and metabolism in oxidative cancer cells

Cell Cycle

Volumn 15, Issue 1, 2016, Pages 72-83

  Pérez Escuredo, Jhudit ^a   Dadhich, Rajesh K ^a   Dhup, Suveera ^a   Cacace, Andrea ^a   Van Hée, Vincent F ^a   De Saedeleer, Christophe J ^a   Sboarina, Martina ^a   Rodriguez, Fabien ^a   Fontenille, Marie Joséphine ^a   Brisson, Lucie ^a   Porporato, Paolo E ^a   Sonveaux, Pierre ^a  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

C Myc; Cancer; Glutamine; Glutaminolysis; Hypoxia inducible factor (HIF); Hypoxiainducible factor 2 (HIF 2); Lactate signaling; Monocarboxylate transporter 1 (MCT1); Tumor metabolism

Indexed keywords

GLUTAMINASE; GLUTAMINE; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; MYC PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; COTRANSPORTER; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; GLS1 PROTEIN, HUMAN; MONOCARBOXYLATE TRANSPORT PROTEIN 1; MONOCARBOXYLATE TRANSPORTER;

AEROBIC METABOLISM; AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ARTICLE; CANCER CELL; CATABOLISM; CELL METABOLISM; CONTROLLED STUDY; HELA CELL LINE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; OXYGEN CONSUMPTION; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; MALE; METABOLISM; MOUSE; NEOPLASM; NUDE MOUSE; OXIDATION REDUCTION REACTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; GLUTAMINASE; GLUTAMINE; HELA CELLS; HUMANS; LACTIC ACID; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MONOCARBOXYLIC ACID TRANSPORTERS; NEOPLASMS; OXIDATION-REDUCTION; SYMPORTERS;

EID: 84964300029     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1120930     Document Type: Article

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