The SIRT1/HIF2α axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy

Cancer Research

Volumn 74, Issue 19, 2014, Pages 5507-5519

  Corbet, Cyril ^a   Draoui, Nihed ^a   Polet, Florence ^a   Pinto, Adan ^a   Drozak, Xavier ^a   Riant, Olivier ^a   Feron, Olivier ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; GLUCOSE; GLUTAMINE; SIRT1 PROTEIN, HUMAN; SIRTUIN 1;

ACIDOSIS; CHRONIC DISEASE; GLYCOLYSIS; HUMAN; METABOLISM; NEOPLASMS; PHYSIOLOGY; TUMOR CELL LINE;

ACIDOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; CHRONIC DISEASE; GLUCOSE; GLUTAMINE; GLYCOLYSIS; HUMANS; NEOPLASMS; SIRTUIN 1;

EID: 84907485996     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0705     Document Type: Article

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