Lactate does not activate NF-κB in oxidative tumor cells

Frontiers in Pharmacology

Volumn 6, Issue OCT, 2015, Pages 228-

  Van Hée, Vincent F ^a   Pérez Escuredo, Jhudit ^a   Cacace, Andrea ^a   Copetti, Tamara ^a   Sonveaux, Pierre ^a  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

Cancer metabolism; Lactate signaling; Malate aspartate shuttle; Mitochondria; NAD(P)H oxidases (Nox); NADH; Nuclear factor B; Oxidative phosphorylation (OXPHOS)

Indexed keywords

ASPARTIC ACID; DIETHYL PYROCARBONATE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYDROGEN PEROXIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE 1; LACTIC ACID; MALIC ACID; NITRATE REDUCTASE (NADH); PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PYRUVATE KINASE; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; ROTENONE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ARTICLE; CONTROLLED STUDY; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TUMOR CELL;

EID: 84949659668     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00228     Document Type: Article

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