메뉴 건너뛰기




Volumn 89, Issue , 2016, Pages 1064-1070

Impact of chlorogenic acids from coffee on urine metabolome in healthy human subjects

Author keywords

Biomarkers; Chlorogenic acids; Coffee; Metabolomics; Multilevel PLS DA; NMR

Indexed keywords

BEVERAGES; BIOMARKERS; BODY FLUIDS; CAFFEINE; DISCRIMINANT ANALYSIS; LEAST SQUARES APPROXIMATIONS; NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; PROPIONIC ACID;

EID: 84964265442     PISSN: 09639969     EISSN: 18737145     Source Type: Journal    
DOI: 10.1016/j.foodres.2016.03.038     Document Type: Article
Times cited : (27)

References (53)
  • 1
    • 79955630021 scopus 로고    scopus 로고
    • Antioxidant-rich coffee reduces DNA damage, elevates glutathione status and contributes to weight control: Results from an intervention study
    • Bakuradze, T., Boehm, N., Janzowski, C., Lang, R., Hofmann, T., Stockis, J.-P.,.. Eisenbrand, G., Antioxidant-rich coffee reduces DNA damage, elevates glutathione status and contributes to weight control: Results from an intervention study. Molecular Nutrition & Food Research 55:5 (2011), 793–797, 10.1002/mnfr.201100093.
    • (2011) Molecular Nutrition & Food Research , vol.55 , Issue.5 , pp. 793-797
    • Bakuradze, T.1    Boehm, N.2    Janzowski, C.3    Lang, R.4    Hofmann, T.5    Stockis, J.-P.6    Eisenbrand, G.7
  • 2
    • 70349308395 scopus 로고    scopus 로고
    • Trigonelline is a novel phytoestrogen in
    • Beans, C., Allred, K.F., Yackley, K.M., Vanamala, J., Allred, C.D., Trigonelline is a novel phytoestrogen in. 2009, 1833–1838, 10.3945/jn.109.108001.1833.
    • (2009) , pp. 1833-1838
    • Beans, C.1    Allred, K.F.2    Yackley, K.M.3    Vanamala, J.4    Allred, C.D.5
  • 3
    • 22644435735 scopus 로고    scopus 로고
    • Investigation of aromatic compounds in roasted cocoa powder
    • Bonvehí, J.S., Investigation of aromatic compounds in roasted cocoa powder. European Food Research and Technology 221:1–2 (2005), 19–29, 10.1007/s00217-005-1147-y.
    • (2005) European Food Research and Technology , vol.221 , Issue.1-2 , pp. 19-29
    • Bonvehí, J.S.1
  • 4
    • 84908507885 scopus 로고    scopus 로고
    • NMR-based metabolomics: From sample preparation to applications in nutrition research
    • Brennan, L., NMR-based metabolomics: From sample preparation to applications in nutrition research. Progress in Nuclear Magnetic Resonance Spectroscopy 83 (2014), 42–49, 10.1016/j.pnmrs.2014.09.001.
    • (2014) Progress in Nuclear Magnetic Resonance Spectroscopy , vol.83 , pp. 42-49
    • Brennan, L.1
  • 5
    • 0034657786 scopus 로고    scopus 로고
    • Chlorogenic acids and other cinnamates — Nature, occurrence, dietary burden, absorption and metabolism.
    • (< 1033::AID-JSFA595 > 3.0.CO;2-T)
    • Clifford, M.N., Chlorogenic acids and other cinnamates — Nature, occurrence, dietary burden, absorption and metabolism. Journal of the Science of Food and Agriculture 1043:October 1999 (2000), 1033–1043 (http://doi.org/ http://dx.doi.org/10.1002/(SICI)1097-0010(20000515)80:7 < 1033::AID-JSFA595 > 3.0.CO;2-T).
    • (2000) Journal of the Science of Food and Agriculture , vol.1043 , Issue.October 1999 , pp. 1033-1043
    • Clifford, M.N.1
  • 7
    • 84893039492 scopus 로고    scopus 로고
    • Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: A systematic review and a dose–response meta-analysis
    • Ding, M., Bhupathiraju, S.N., Chen, M., van Dam, R.M., Hu, F.B., Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: A systematic review and a dose–response meta-analysis. Diabetes Care 37:2 (2014), 569–586, 10.2337/dc13-1203.
    • (2014) Diabetes Care , vol.37 , Issue.2 , pp. 569-586
    • Ding, M.1    Bhupathiraju, S.N.2    Chen, M.3    van Dam, R.M.4    Hu, F.B.5
  • 8
    • 84922749373 scopus 로고    scopus 로고
    • A metabolomics-driven approach to predict cocoa product consumption by designing a multimetabolite biomarker model in free-living subjects from the PREDIMED study
    • Garcia-Aloy, M., Llorach, R., Urpi-Sarda, M., Auregui, O., Corella, D., Ruiz-Canela, M.,.. Andres-Lacueva, C., A metabolomics-driven approach to predict cocoa product consumption by designing a multimetabolite biomarker model in free-living subjects from the PREDIMED study. Mol. Nutr. Food Research 59 (2015), 212–220, 10.1002/mnfr.201400434.
    • (2015) Mol. Nutr. Food Research , vol.59 , pp. 212-220
    • Garcia-Aloy, M.1    Llorach, R.2    Urpi-Sarda, M.3    Auregui, O.4    Corella, D.5    Ruiz-Canela, M.6    Andres-Lacueva, C.7
  • 9
    • 0033863295 scopus 로고    scopus 로고
    • Identification of proline-based diketopiperazines in roasted coffee
    • Ginz, M., Engelhardt, U.H., Identification of proline-based diketopiperazines in roasted coffee. Journal of Agricultural and Food Chemistry 48:8 (2000), 3528–3532, 10.1021/jf991256v.
    • (2000) Journal of Agricultural and Food Chemistry , vol.48 , Issue.8 , pp. 3528-3532
    • Ginz, M.1    Engelhardt, U.H.2
  • 10
    • 33751004148 scopus 로고    scopus 로고
    • Microbial metabolism of caffeic acid and its esters chlorogenic and caftaric acids by human faecal microbiota in vitro
    • Gonthier, M.P., Remesy, C., Scalbert, a, Cheynier, V., Souquet, J.M., Poutanen, K., Aura, a M., Microbial metabolism of caffeic acid and its esters chlorogenic and caftaric acids by human faecal microbiota in vitro. Biomedicine and Pharmacotherapy 60:9 (2006), 536–540, 10.1016/j.biopha.2006.07.084.
    • (2006) Biomedicine and Pharmacotherapy , vol.60 , Issue.9 , pp. 536-540
    • Gonthier, M.P.1    Remesy, C.2    Scalbert, A.3    Cheynier, V.4    Souquet, J.M.5    Poutanen, K.6    Aura, A.M.7
  • 11
    • 0038653491 scopus 로고    scopus 로고
    • Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats
    • Gonthier, M.-P., Verny, M.-A., Besson, C., Rémésy, C., Scalbert, A., Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats. The Journal of Nutrition 133:6 (2003), 1853–1859.
    • (2003) The Journal of Nutrition , vol.133 , Issue.6 , pp. 1853-1859
    • Gonthier, M.-P.1    Verny, M.-A.2    Besson, C.3    Rémésy, C.4    Scalbert, A.5
  • 12
    • 84996803137 scopus 로고    scopus 로고
    • Serum biomarkers of habitual coffee consumption may provide insight into the mechanism underlying the association between coffee consumption and colorectal cancer
    • Guertin, K. a, Loftfield, E., Boca, S.M., Sampson, J.N., Moore, S.C., Xiao, Q.,.. Sinha, R., Serum biomarkers of habitual coffee consumption may provide insight into the mechanism underlying the association between coffee consumption and colorectal cancer. Vols. 1 – 5, (C), 2015, 1–12, 10.3945/ajcn.114.096099.
    • (2015) , vol.5C , pp. 1-12
    • Guertin, K.A.1    Loftfield, E.2    Boca, S.M.3    Sampson, J.N.4    Moore, S.C.5    Xiao, Q.6    Sinha, R.7
  • 13
    • 84903535630 scopus 로고    scopus 로고
    • Metabolomics in nutritional epidemiology: Identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations
    • Guertin, K.A., Moore, S.C., Sampson, J.N., Huang, W.-Y., Xiao, Q., Stolzenberg-Solomon, R.Z.,.. Cross, A.J., Metabolomics in nutritional epidemiology: Identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations. The American Journal of Clinical Nutrition 100 (2014), 208–217, 10.3945/ajcn.113.078758.
    • (2014) The American Journal of Clinical Nutrition , vol.100 , pp. 208-217
    • Guertin, K.A.1    Moore, S.C.2    Sampson, J.N.3    Huang, W.-Y.4    Xiao, Q.5    Stolzenberg-Solomon, R.Z.6    Cross, A.J.7
  • 15
    • 79951817432 scopus 로고    scopus 로고
    • Dietary polyphenols and human gut microbiota: A review
    • Hervert-Hernández, D., Goñi, I., Dietary polyphenols and human gut microbiota: A review. Food Reviews International 27:2 (2011), 154–169, 10.1080/87559129.2010.535233.
    • (2011) Food Reviews International , vol.27 , Issue.2 , pp. 154-169
    • Hervert-Hernández, D.1    Goñi, I.2
  • 16
    • 33644631621 scopus 로고    scopus 로고
    • Coffee and health: A review of recent human research
    • Higdon, J., Frei, B., Coffee and health: A review of recent human research. Critical Reviews in Food Science and Nutrition 46:2 (2006), 101–123, 10.1080/10408390500400009.
    • (2006) Critical Reviews in Food Science and Nutrition , vol.46 , Issue.2 , pp. 101-123
    • Higdon, J.1    Frei, B.2
  • 17
    • 20344396621 scopus 로고    scopus 로고
    • Branched-chain amino acid metabolism: Implications for establishing safe intakes
    • Retrieved from
    • Hutson, S.M., Sweatt, A.J., LaNoue, K.F., Branched-chain amino acid metabolism: Implications for establishing safe intakes. The Journal of Nutrition 135:6 (2005), 1557S–11564 Retrieved from http://jn.nutrition.org/cgi/content/long/135/6/1557S.
    • (2005) The Journal of Nutrition , vol.135 , Issue.6 , pp. 1557S-11564
    • Hutson, S.M.1    Sweatt, A.J.2    LaNoue, K.F.3
  • 18
    • 73149107237 scopus 로고    scopus 로고
    • Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: A systematic review with meta-analysis
    • Huxley, R., Lee, C.M.Y., Barzi, F., Timmermeister, L., Czernichow, S., Perkovic, V.,.. Woodward, M., Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: A systematic review with meta-analysis. Archives of Internal Medicine 169:22 (2009), 2053–2063, 10.1001/archinternmed.2009.439.
    • (2009) Archives of Internal Medicine , vol.169 , Issue.22 , pp. 2053-2063
    • Huxley, R.1    Lee, C.M.Y.2    Barzi, F.3    Timmermeister, L.4    Czernichow, S.5    Perkovic, V.6    Woodward, M.7
  • 20
    • 0142120181 scopus 로고    scopus 로고
    • Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: Glycemic effects of chlorogenic acid and caffeine
    • Johnston, K.L., Clifford, M.N., Morgan, L.M., Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: Glycemic effects of chlorogenic acid and caffeine. American Journal of Clinical Nutrition 78:4 (2003), 728–733, 10.1021/jf980737w.
    • (2003) American Journal of Clinical Nutrition , vol.78 , Issue.4 , pp. 728-733
    • Johnston, K.L.1    Clifford, M.N.2    Morgan, L.M.3
  • 21
    • 0003619146 scopus 로고    scopus 로고
    • Design and analysis of cross-over trials
    • 3rd ed. CRC Press Retrieved from
    • Jones, B., Kenward, M.G., Design and analysis of cross-over trials. 3rd ed., 2014, CRC Press Retrieved from https://books.google.com/books?id=aErNBQAAQBAJ&pgis=1.
    • (2014)
    • Jones, B.1    Kenward, M.G.2
  • 22
    • 14844282069 scopus 로고    scopus 로고
    • Coffee, liver enzymes, cirrhosis and liver cancer
    • La Vecchia, C., Coffee, liver enzymes, cirrhosis and liver cancer. Journal of Hepatology 42:4 (2005), 444–446, 10.1016/j.jhep.2005.01.004.
    • (2005) Journal of Hepatology , vol.42 , Issue.4 , pp. 444-446
    • La Vecchia, C.1
  • 23
    • 80155186901 scopus 로고    scopus 로고
    • Urinary N-methylpyridinium and trigonelline as candidate dietary biomarkers of coffee consumption
    • Lang, R., Wahl, A., Stark, T., Hofmann, T., Urinary N-methylpyridinium and trigonelline as candidate dietary biomarkers of coffee consumption. Molecular Nutrition and Food Research 55:11 (2011), 1613–1623, 10.1002/mnfr.201000656.
    • (2011) Molecular Nutrition and Food Research , vol.55 , Issue.11 , pp. 1613-1623
    • Lang, R.1    Wahl, A.2    Stark, T.3    Hofmann, T.4
  • 24
    • 70350694448 scopus 로고    scopus 로고
    • integrOmics: An R package to unravel relationships between two omics datasets
    • Lê Cao, K.-A., González, I., Déjean, S., integrOmics: An R package to unravel relationships between two omics datasets. Bioinformatics (Oxford, England) 25:21 (2009), 2855–2856, 10.1093/bioinformatics/btp515.
    • (2009) Bioinformatics (Oxford, England) , vol.25 , Issue.21 , pp. 2855-2856
    • Lê Cao, K.-A.1    González, I.2    Déjean, S.3
  • 25
    • 84873350824 scopus 로고    scopus 로고
    • Data-driven strategy for the discovery of potential urinary biomarkers of habitual dietary exposure
    • Lloyd, A.J., Beckmann, M., Haldar, S., Seal, C., Brandt, K., Draper, J., Data-driven strategy for the discovery of potential urinary biomarkers of habitual dietary exposure. American Journal of Clinical Nutrition 97:C (2013), 377–389, 10.3945/ajcn.112.048033.
    • (2013) American Journal of Clinical Nutrition , vol.97 , Issue.100 , pp. 377-389
    • Lloyd, A.J.1    Beckmann, M.2    Haldar, S.3    Seal, C.4    Brandt, K.5    Draper, J.6
  • 26
    • 84888135487 scopus 로고    scopus 로고
    • Catabolism of coffee chlorogenic acids by human colonic microbiota
    • Ludwig, I.a., Paz de Peña, M., Concepción, C., Alan, C., Catabolism of coffee chlorogenic acids by human colonic microbiota. BioFactors 39:6 (2013), 623–632, 10.1002/biof.1124.
    • (2013) BioFactors , vol.39 , Issue.6 , pp. 623-632
    • Ludwig, I.A.1    Paz de Peña, M.2    Concepción, C.3    Alan, C.4
  • 27
    • 67649844515 scopus 로고    scopus 로고
    • Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans.
    • Retrieved from
    • Moon, J.-K., Shibamoto, T., Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans. Journal of Agricultural and Food Chemistry 57:13 (2009), 5823–5831 Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/19579294.
    • (2009) Journal of Agricultural and Food Chemistry , vol.57 , Issue.13 , pp. 5823-5831
    • Moon, J.-K.1    Shibamoto, T.2
  • 28
    • 84936773598 scopus 로고    scopus 로고
    • Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: A Mendelian randomization study
    • Nordestgaard, a.T., Thomsen, M., Nordestgaard, B.G., Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: A Mendelian randomization study. International Journal of Epidemiology 01 (2015), 1–15, 10.1093/ije/dyv083.
    • (2015) International Journal of Epidemiology , vol.1 , pp. 1-15
    • Nordestgaard, A.T.1    Thomsen, M.2    Nordestgaard, B.G.3
  • 29
    • 0015408508 scopus 로고
    • The identification and metabolic origin of 2-furoylglycine and 2.5-furandicarboxylic acid in human urine.
    • Retrieved from
    • Pettersen, J.E., Jellum, E., The identification and metabolic origin of 2-furoylglycine and 2.5-furandicarboxylic acid in human urine. Clinica Chimica Acta; International Journal of Clinical Chemistry 41 (1972), 199–207 Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/4630229.
    • (1972) Clinica Chimica Acta; International Journal of Clinical Chemistry , vol.41 , pp. 199-207
    • Pettersen, J.E.1    Jellum, E.2
  • 31
    • 84947808557 scopus 로고    scopus 로고
    • Metabolome responses to physiological and nutritional challenges
    • Puiggròs, F., Canela, N., Arola, L., Metabolome responses to physiological and nutritional challenges. Current opinion in food science, 2015, 10.1016/j.cofs.2015.06.001.
    • (2015) Current opinion in food science
    • Puiggròs, F.1    Canela, N.2    Arola, L.3
  • 34
    • 84899500823 scopus 로고    scopus 로고
    • New biomarkers of coffee consumption identified by the non-targeted metabolomic profiling of cohort study subjects
    • Rothwell, J.A., Fillâtre, Y., Martin, J.-F., Lyan, B., Pujos-Guillot, E., Fezeu, L.,.. Manach, C., New biomarkers of coffee consumption identified by the non-targeted metabolomic profiling of cohort study subjects. PloS One, 9(4), 2014, e93474, 10.1371/journal.pone.0093474.
    • (2014) PloS One , vol.9 , Issue.4
    • Rothwell, J.A.1    Fillâtre, Y.2    Martin, J.-F.3    Lyan, B.4    Pujos-Guillot, E.5    Fezeu, L.6    Manach, C.7
  • 35
    • 84906317305 scopus 로고    scopus 로고
    • Metabolomic analysis of amino acid and energy metabolism in rats supplemented with chlorogenic acid
    • Ruan, Z., Yang, Y., Zhou, Y., Wen, Y., Sheng, D.,.. Yin, Y., Metabolomic analysis of amino acid and energy metabolism in rats supplemented with chlorogenic acid. 2014, 10.1007/s00726-014-1762-7.
    • (2014)
    • Ruan, Z.1    Yang, Y.2    Zhou, Y.3    Wen, Y.4    Sheng, D.5    Yin, Y.6
  • 38
    • 84903138131 scopus 로고    scopus 로고
    • Cross-over trials in clinical research.
    • Retrieved from
    • Senn, S., Cross-over trials in clinical research.., 2002 Retrieved from https://books.google.com/books?hl=es&lr=&id=MWbHzwpPTgEC&pgis=1.
    • (2002)
    • Senn, S.1
  • 39
    • 84891097521 scopus 로고    scopus 로고
    • Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging
    • Shukitt-Hale, B., Miller, M.G., Chu, Y.F., Lyle, B.J., Joseph, J.a., Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging. Age 35:6 (2013), 2183–2192, 10.1007/s11357-012-9509-4.
    • (2013) Age , vol.35 , Issue.6 , pp. 2183-2192
    • Shukitt-Hale, B.1    Miller, M.G.2    Chu, Y.F.3    Lyle, B.J.4    Joseph, J.A.5
  • 41
    • 67650802353 scopus 로고    scopus 로고
    • Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: Identification of biomarkers of coffee consumption
    • Stalmach, A., Mullen, W., Barron, D., Uchida, K., Yokota, T., Cavin, C.,.. Crozier, A., Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: Identification of biomarkers of coffee consumption. Drug Metabolism and Disposition 37:8 (2009), 1749–1758, 10.1124/dmd.109.028019.
    • (2009) Drug Metabolism and Disposition , vol.37 , Issue.8 , pp. 1749-1758
    • Stalmach, A.1    Mullen, W.2    Barron, D.3    Uchida, K.4    Yokota, T.5    Cavin, C.6    Crozier, A.7
  • 42
    • 0030752316 scopus 로고    scopus 로고
    • The cholesterol-raising factor from coffee beans
    • Urgert, R., Katan, M.B., The cholesterol-raising factor from coffee beans. Annual Review of Nutrition 17 (1997), 305–324, 10.1146/annurev.nutr.17.1.305.
    • (1997) Annual Review of Nutrition , vol.17 , pp. 305-324
    • Urgert, R.1    Katan, M.B.2
  • 43
    • 0037048946 scopus 로고    scopus 로고
    • Coffee consumption and risk of type 2 diabetes mellitus treatment of active Crohn's disease with recombinant human
    • van Dam, R.M., Feskens, E.J.M., Coffee consumption and risk of type 2 diabetes mellitus treatment of active Crohn's disease with recombinant human. Vol. 360, 2002, 1477–1478.
    • (2002) , vol.360 , pp. 1477-1478
    • van Dam, R.M.1    Feskens, E.J.M.2
  • 44
    • 21444448910 scopus 로고    scopus 로고
    • Coffee consumption and risk of type 2 diabetes: A systematic review
    • Van Dam, R.M., Hu, F.B., Coffee consumption and risk of type 2 diabetes: A systematic review. JAMA 294:1 (2005), 97–104, 10.1001/jama.294.1.97.
    • (2005) JAMA , vol.294 , Issue.1 , pp. 97-104
    • Van Dam, R.M.1    Hu, F.B.2
  • 46
    • 84864910045 scopus 로고    scopus 로고
    • (1)H-NMR-based metabolomic analysis of the effect of moderate wine consumption on subjects with cardiovascular risk factors
    • Vázquez-Fresno, R., Llorach, R., Alcaro, F., Rodríguez, M.Á, Vinaixa, M., Chiva-Blanch, G.,.. Andrés-Lacueva, C., (1)H-NMR-based metabolomic analysis of the effect of moderate wine consumption on subjects with cardiovascular risk factors. Electrophoresis 33:15 (2012), 2345–2354, 10.1002/elps.201100646.
    • (2012) Electrophoresis , vol.33 , Issue.15 , pp. 2345-2354
    • Vázquez-Fresno, R.1    Llorach, R.2    Alcaro, F.3    Rodríguez, M.Á.4    Vinaixa, M.5    Chiva-Blanch, G.6    Andrés-Lacueva, C.7
  • 47
    • 80052685589 scopus 로고    scopus 로고
    • Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: A randomized controlled trial
    • Wedick, N.M., Brennan, A.M., Sun, Q., Hu, F.B., Mantzoros, C.S., Van Dam, R.M., Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: A randomized controlled trial. Nutrition Journal, 10, 2011, 93, 10.1186/1475-2891-10-93.
    • (2011) Nutrition Journal , vol.10 , pp. 93
    • Wedick, N.M.1    Brennan, A.M.2    Sun, Q.3    Hu, F.B.4    Mantzoros, C.S.5    Van Dam, R.M.6
  • 48
    • 84856516171 scopus 로고    scopus 로고
    • Roasting process of coffee beans as studied by nuclear magnetic resonance: Time course of changes in composition
    • Wei, F., Furihata, K., Koda, M., Hu, F., Miyakawa, T., Tanokura, M., Roasting process of coffee beans as studied by nuclear magnetic resonance: Time course of changes in composition. Journal of Agricultural and Food Chemistry 60:4 (2012), 1005–1012, 10.1021/jf205315r.
    • (2012) Journal of Agricultural and Food Chemistry , vol.60 , Issue.4 , pp. 1005-1012
    • Wei, F.1    Furihata, K.2    Koda, M.3    Hu, F.4    Miyakawa, T.5    Tanokura, M.6
  • 49
    • 78049432112 scopus 로고    scopus 로고
    • Colonic metabolites of berry polyphenols: The missing link to biological activity?
    • Williamson, G., Clifford, M.N., Colonic metabolites of berry polyphenols: The missing link to biological activity?. The British Journal of Nutrition 104 Suppl (2010), S48–S66, 10.1017/S0007114510003946.
    • (2010) The British Journal of Nutrition , vol.104 Suppl , pp. S48-S66
    • Williamson, G.1    Clifford, M.N.2
  • 50
    • 48949118698 scopus 로고    scopus 로고
    • Metabolomics: Applications to food science and nutrition research
    • Wishart, D.S., Metabolomics: Applications to food science and nutrition research. Trends in Food Science & Technology 19:9 (2008), 482–493, 10.1016/j.tifs.2008.03.003.
    • (2008) Trends in Food Science & Technology , vol.19 , Issue.9 , pp. 482-493
    • Wishart, D.S.1
  • 52
    • 84896288057 scopus 로고    scopus 로고
    • Recent developments and applications of metabolomics in microbiological investigations
    • Xu, Y.-J., Wang, C., Ho, W.E., Ong, C.N., Recent developments and applications of metabolomics in microbiological investigations. TrAC Trends in Analytical Chemistry 56 (2014), 37–48, 10.1016/j.trac.2013.12.009.
    • (2014) TrAC Trends in Analytical Chemistry , vol.56 , pp. 37-48
    • Xu, Y.-J.1    Wang, C.2    Ho, W.E.3    Ong, C.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.