Urinary N-methylpyridinium and trigonelline as candidate dietary biomarkers of coffee consumption

Molecular Nutrition and Food Research

Volumn 55, Issue 11, 2011, Pages 1613-1623

  Lang, Roman ^a   Wahl, Anika ^a   Stark, Timo ^a   Hofmann, Thomas ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Coffee; Compliance; Dietary biomarker; N Methylpyridinium; Trigonelline

Indexed keywords

1 METHYLPYRIDINIUM; 1-METHYLPYRIDINIUM; ALKALOID; BIOLOGICAL MARKER; PYRIDINIUM DERIVATIVE; TRIGONELLINE;

ADULT; ARTICLE; CALIBRATION; CHEMICAL STRUCTURE; CHEMISTRY; COFFEE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; PATIENT COMPLIANCE; PILOT STUDY; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY; TIME; URINE;

ADULT; ALKALOIDS; BIOLOGICAL MARKERS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COFFEE; FEMALE; HUMANS; MALE; MOLECULAR STRUCTURE; PATIENT COMPLIANCE; PILOT PROJECTS; PYRIDINIUM COMPOUNDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TIME FACTORS; YOUNG ADULT;

EID: 80155186901     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201000656     Document Type: Article

References (23)

1. Lindsay, J., Laurin, D., Verreault, R. et al., Risk for Alzheimer's disease: a prospective analysis from the Canadian study of health and aging. Am. J. Epidemiol. 2002, 56, 445-453.
2. Hu, G., Bidel, S., Jousilahti, P., Antikainen, R., Tuomilehte, J., Coffee and tea consumption and the risk of Parkinson's Disease. Mov. Disord. 2007, 22, 2242-2248.
3. van Dam, R. M., Hu, F. B., Coffee consumption and risk of type 2 diabetes: a systematic review. J Am. Med. Assoc. 2005, 294, 97-104.
4. Smith, B., Wingard, D. L., Smith, T. C., Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose? Diabetes Care 2006, 29, 2385-2390.
5. Klastsky, A. L., Morton, C., Udaltsova, N., Friedman, G. D., Coffee, cirrhosis, and transaminase enzymes. Arch. Intern. Med. 2006, 166, 1190-1195.
6. Glade, M. J., Caffeine - not just a stimulant. Nutrition 2010, 932-938.
7. Stalmach, A., Mullen, W., Barron, D. et al., Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption. Drug Metab. Dispos. 2009, 37, 1749-1758.
8. Monteiro, M., Farah, A., Perrone, D., Trugo, L. C., Donangelo, C., Chlorogenic acid compounds from coffee are differentially absorbed and metabolized in humans. J. Nutr. 2007, 137, 2196-2201.
9. Viani, R., Horman, I., Thermal behaviour of trigonelline. J. Food Sci. 1974, 39, 1216-1217.
10. Smith, R. F., Niacin content in coffee. Nature 1963, 197, 1321.
11. Yoshinari, O., Sato, H., Igarashi, K., Anti-diabetic effects of pumpkin and its components, trigonelline and nicotinic acid, on Goto Kakizaki rats. Biosci. Biotechnol. Biochem. 2009, 73, 103-1041.
12. van Dijk, A. E., Olthoff, M. R., Meeuse, J. C., Seebus, E., Heine, R. J., van Dam, R. M., Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. Diabetes Care 2009, 32, 1023-1025.
13. Stadler, R. H., Varga, N., Hau, J., Vera, F. A., Welti, D., Alkylpyridiniums. 1. Formation in model systems via thermal degradation of trigonelline. J. Agric. Food Chem. 2002, 50, 1192-1199.
14. Somoza, V., Lindenmeier, M., Wenzel, E., Frank, O., Erbersdobler, H. F., Hofmann, T., Activity guided identification of a chemopreventive compound in coffee beverage using in vitro and in vivo techniques. J. Agric. Food Chem. 2003, 51, 6861-6869.
15. Fehlau, R., Netter, K. J., Einfluss von unbehandeltem und reizarm veredeltem Kaffee und Carbonsäure-5-hydroxytryptamiden auf die Magenschleimhaut der Ratte (in German). Z. Gastroenterol. 1990, 28, 234-238.
16. van Cruchten, S. T. J., de Haan, L. H. J., Mulder, P. P. J. et al., The role of epoxidation and electrophile responsive element regulated gene transcription in the potentially beneficial and harmful effects of the coffee components cafestol and kahweol. J. Nutr. Biochem. 2010, 21, 757-763.
17. Aggett, P. J., Antoine, J.-M., Aps, N.-G. et al., Consensus on criteria. Eur. J. Nutr. 2005, 44, I/5-I/30.
18. Landberg, R., Kamal-Eldin, A., Andersson, A., Vessby, B., Aman, P., Alkylresorcinols as biomarkers of whole grain wheat and rye intake: plasma concentration and intake estimated from dietary records. Am. J. Nutr. 2008, 87, 832-838.
19. Clifford, M. N., Chlorogenic acids and other cinnamates - nature, occurrence and dietary burden. J. Sci. Food Agric. 1999, 79, 362-372.
20. Lang, R., Wahl, A., Skurk, T. et al., Development of a hydrophilic liquid interaction chromatography - tandem mass spectroscopy based stable isotope dilution analysis and pharmacokinetic studies on bioactives pyridines in human plasma and urine after coffee consumption. Anal. Chem. 2010, 82, 1486-1497.
21. Brooks, T., Keevil, C. W., A simple artificial urine for the growth of urinary pathogens. Lett. Appl. Microbiol. 1997, 24, 203-206.
22. D'Souza, J., Caldwell, J., Smith, R. L., Species variations in the N-methylation and quaternization of 14C Pyridine. Xenobiotica 1980, 10, 151-157.
23. Sarett, H. P., Perlzweig, W. A., Levy, E. D., Synthesis and excretion of trigonelline. J. Biol. Chem. 1940, 135, 483-485.