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Volumn 118, Issue 8, 2016, Pages 1294-1312

The importance of biological sex and estrogen in rodent models of cardiovascular health and disease

Author keywords

cardiovascular diseases; estrogens; gonadal steroid hormones; heart failure; sex characteristics

Indexed keywords

ESTROGEN; HORMONE; ION CHANNEL; N(G) NITROARGININE METHYL ESTER;

EID: 84963825556     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.307509     Document Type: Review
Times cited : (141)

References (202)
  • 1
    • 77649126524 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2010 update: A report from the American Heart Association
    • Writing Group Members; American Heart Association Statistics Committee and Stroke Statistics Subcommittee Writing Group Members; American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D, Adams RJ, Brown TM, Writing Group Members; American Heart Association Statistics Committee and Stroke Statistics Subcommittee Writing Group Members; American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 2010 121 e46 e215. doi: 10.1161/CIRCULATIONAHA.109.192667
    • (2010) Circulation , vol.121 , pp. e46-e215
    • Lloyd-Jones, D.1    Adams, R.J.2    Brown, T.M.3
  • 2
    • 79952901484 scopus 로고    scopus 로고
    • Effectiveness-based guidelines for the prevention of cardiovascular disease in women-2011 update: A guideline from the American Heart Association
    • American Heart Association American Heart Association
    • Mosca L, Benjamin EJ, Berra K, American Heart Association American Heart Association Effectiveness-based guidelines for the prevention of cardiovascular disease in women-2011 update: a guideline from the American Heart Association. J Am Coll Cardiol 2011 57 1404 1423. doi: 10.1016/j.jacc.2011.02.005
    • (2011) J Am Coll Cardiol , vol.57 , pp. 1404-1423
    • Mosca, L.1    Benjamin, E.J.2    Berra, K.3
  • 3
    • 0027477440 scopus 로고
    • Results of percutaneous transluminal coronary angioplasty in women. 1985-1986 National Heart, Lung, and Blood Institute's Coronary Angioplasty Registry
    • Kelsey SF, James M, Holubkov AL, Holubkov R, Cowley MJ, Detre KM, Results of percutaneous transluminal coronary angioplasty in women. 1985-1986 National Heart, Lung, and Blood Institute's Coronary Angioplasty Registry. Circulation 1993 87 720 727
    • (1993) Circulation , vol.87 , pp. 720-727
    • Kelsey, S.F.1    James, M.2    Holubkov, A.L.3    Holubkov, R.4    Cowley, M.J.5    Detre, K.M.6
  • 4
    • 33847410075 scopus 로고    scopus 로고
    • Sex and the cardiovascular system: The intriguing tale of how women and men regulate cardiovascular function differently
    • Huxley VH, Sex and the cardiovascular system: the intriguing tale of how women and men regulate cardiovascular function differently. Adv Physiol Educ 2007 31 17 22. doi: 10.1152/advan.00099.2006
    • (2007) Adv Physiol Educ , vol.31 , pp. 17-22
    • Huxley, V.H.1
  • 5
    • 31644443751 scopus 로고    scopus 로고
    • Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part I: Gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies
    • WISE Investigators WISE Investigators
    • Shaw LJ, Bairey Merz CN, Pepine CJ, WISE Investigators WISE Investigators Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies. J Am Coll Cardiol 2006 47 S4 S20. doi: 10.1016/j.jacc.2005.01.072
    • (2006) J Am Coll Cardiol , vol.47 , pp. S4-S20
    • Shaw, L.J.1    Bairey Merz, C.N.2    Pepine, C.J.3
  • 10
    • 84900526349 scopus 로고    scopus 로고
    • Policy: NIH to balance sex in cell and animal studies
    • Clayton JA, Collins FS, Policy: NIH to balance sex in cell and animal studies. Nature 2014 509 282 283
    • (2014) Nature , vol.509 , pp. 282-283
    • Clayton, J.A.1    Collins, F.S.2
  • 11
    • 0037139248 scopus 로고    scopus 로고
    • Gender differences and normal left ventricular anatomy in an adult population free of hypertension. A cardiovascular magnetic resonance study of the Framingham Heart Study Offspring cohort
    • Salton CJ, Chuang ML, O'Donnell CJ, Kupka MJ, Larson MG, Kissinger KV, Edelman RR, Levy D, Manning WJ, Gender differences and normal left ventricular anatomy in an adult population free of hypertension. A cardiovascular magnetic resonance study of the Framingham Heart Study Offspring cohort. J Am Coll Cardiol 2002 39 1055 1060
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1055-1060
    • Salton, C.J.1    Chuang, M.L.2    O'Donnell, C.J.3    Kupka, M.J.4    Larson, M.G.5    Kissinger, K.V.6    Edelman, R.R.7    Levy, D.8    Manning, W.J.9
  • 12
    • 0034020315 scopus 로고    scopus 로고
    • Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging
    • Sandstede J, Lipke C, Beer M, Hofmann S, Pabst T, Kenn W, Neubauer S, Hahn D, Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol 2000 10 438 442. doi: 10.1007/s003300050072
    • (2000) Eur Radiol , vol.10 , pp. 438-442
    • Sandstede, J.1    Lipke, C.2    Beer, M.3    Hofmann, S.4    Pabst, T.5    Kenn, W.6    Neubauer, S.7    Hahn, D.8
  • 13
    • 63549139570 scopus 로고    scopus 로고
    • Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: A cross sectional study
    • Cain PA, Ahl R, Hedstrom E, Ugander M, Allansdotter-Johnsson A, Friberg P, Arheden H, Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: a cross sectional study. BMC Med Imaging 2009 9 2. doi: 10.1186/1471-2342-9-2
    • (2009) BMC Med Imaging , vol.9 , pp. 2
    • Cain, P.A.1    Ahl, R.2    Hedstrom, E.3    Ugander, M.4    Allansdotter-Johnsson, A.5    Friberg, P.6    Arheden, H.7
  • 16
    • 0042889028 scopus 로고    scopus 로고
    • Sex is a potent modifier of the cardiovascular system
    • Leinwand LA, Sex is a potent modifier of the cardiovascular system. J Clin Invest 2003 112 302 307. doi: 10.1172/JCI19429
    • (2003) J Clin Invest , vol.112 , pp. 302-307
    • Leinwand, L.A.1
  • 17
    • 67651165572 scopus 로고    scopus 로고
    • Sex-based cardiac physiology
    • Luczak ED, Leinwand LA, Sex-based cardiac physiology. Annu Rev Physiol 2009 71 1 18. doi: 10.1146/annurev.physiol.010908.163156
    • (2009) Annu Rev Physiol , vol.71 , pp. 1-18
    • Luczak, E.D.1    Leinwand, L.A.2
  • 18
    • 80052567031 scopus 로고    scopus 로고
    • Estrogen signaling and cardiovascular disease
    • Murphy E, Estrogen signaling and cardiovascular disease. Circ Res 2011 109 687 696. doi: 10.1161/CIRCRESAHA.110.236687
    • (2011) Circ Res , vol.109 , pp. 687-696
    • Murphy, E.1
  • 19
    • 33751185765 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice
    • Grandy SA, Howlett SE, Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice. Am J Physiol Heart Circ Physiol 2006 291 H2362 H2370. doi: 10.1152/ajpheart.00070.2006
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H2362-H2370
    • Grandy, S.A.1    Howlett, S.E.2
  • 20
    • 74949128544 scopus 로고    scopus 로고
    • Age-associated changes in excitation-contraction coupling are more prominent in ventricular myocytes from male rats than in myocytes from female rats
    • Howlett SE, Age-associated changes in excitation-contraction coupling are more prominent in ventricular myocytes from male rats than in myocytes from female rats. Am J Physiol Heart Circ Physiol 2010 298 H659 H670. doi: 10.1152/ajpheart.00214.2009
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , pp. H659-H670
    • Howlett, S.E.1
  • 21
    • 84878013172 scopus 로고    scopus 로고
    • Sex differences in mechanisms of cardiac excitation-contraction coupling
    • Parks RJ, Howlett SE, Sex differences in mechanisms of cardiac excitation-contraction coupling. Pflugers Arch 2013 465 747 763. doi: 10.1007/s00424-013-1233-0
    • (2013) Pflugers Arch , vol.465 , pp. 747-763
    • Parks, R.J.1    Howlett, S.E.2
  • 22
    • 77953764849 scopus 로고    scopus 로고
    • Sex differences in mechanisms of cardiac excitation-contraction coupling in rat ventricular myocytes
    • Farrell SR, Ross JL, Howlett SE, Sex differences in mechanisms of cardiac excitation-contraction coupling in rat ventricular myocytes. Am J Physiol Heart Circ Physiol 2010 299 H36 H45. doi: 10.1152/ajpheart.00299.2010
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. H36-H45
    • Farrell, S.R.1    Ross, J.L.2    Howlett, S.E.3
  • 23
    • 31044434071 scopus 로고    scopus 로고
    • The L-type calcium channel in the heart: The beat goes on
    • Bodi I, Mikala G, Koch SE, Akhter SA, Schwartz A, The L-type calcium channel in the heart: the beat goes on. J Clin Invest 2005 115 3306 3317. doi: 10.1172/JCI27167
    • (2005) J Clin Invest , vol.115 , pp. 3306-3317
    • Bodi, I.1    Mikala, G.2    Koch, S.E.3    Akhter, S.A.4    Schwartz, A.5
  • 24
    • 57649180480 scopus 로고    scopus 로고
    • Delayed-rectifier potassium currents and the control of cardiac repolarization: Noble and Tsien 40 years after
    • Nattel S, Delayed-rectifier potassium currents and the control of cardiac repolarization: Noble and Tsien 40 years after. J Physiol 2008 586 5849 5852. doi: 10.1113/jphysiol.2008.163089
    • (2008) J Physiol , vol.586 , pp. 5849-5852
    • Nattel, S.1
  • 25
    • 84900431873 scopus 로고    scopus 로고
    • Cardiac potassium channel subtypes: New roles in repolarization and arrhythmia
    • Schmitt N, Grunnet M, Olesen SP, Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia. Physiol Rev 2014 94 609 653. doi: 10.1152/physrev.00022.2013
    • (2014) Physiol Rev , vol.94 , pp. 609-653
    • Schmitt, N.1    Grunnet, M.2    Olesen, S.P.3
  • 28
    • 77956178351 scopus 로고    scopus 로고
    • Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts
    • Gaborit N, Varro A, Le Bouter S, Szuts V, Escande D, Nattel S, Demolombe S, Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts. J Mol Cell Cardiol 2010 49 639 646. doi: 10.1016/j.yjmcc.2010.06.005
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 639-646
    • Gaborit, N.1    Varro, A.2    Le Bouter, S.3    Szuts, V.4    Escande, D.5    Nattel, S.6    Demolombe, S.7
  • 30
    • 2342566988 scopus 로고    scopus 로고
    • Studying cardiac arrhythmias in the mouse- A reasonable model for probing mechanisms?
    • Nerbonne JM, Studying cardiac arrhythmias in the mouse- A reasonable model for probing mechanisms? Trends Cardiovasc Med 2004 14 83 93. doi: 10.1016/j.tcm.2003.12.006
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 83-93
    • Nerbonne, J.M.1
  • 31
    • 84963827404 scopus 로고    scopus 로고
    • Molecular diversity of ion channels in the mouse heart; A suitable model for cardiac drug development?
    • Totowa, NJ Humana Press In
    • Nerbonne JM, Pugsley MK, Molecular diversity of ion channels in the mouse heart; a suitable model for cardiac drug development? Methods in Pharmacology and Toxicology: Cardiac Drug Development Guide 2003 Totowa, NJ Humana Press 245 269. In
    • (2003) Methods in Pharmacology and Toxicology: Cardiac Drug Development Guide , pp. 245-269
    • Nerbonne, J.M.1    Pugsley, M.K.2
  • 33
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers DM, Cardiac excitation-contraction coupling. Nature 2002 415 198 205. doi: 10.1038/415198a
    • (2002) Nature , vol.415 , pp. 198-205
    • Bers, D.M.1
  • 34
    • 0027340357 scopus 로고
    • Sarcoplasmic reticulum Ca2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes
    • Hove-Madsen L, Bers DM, Sarcoplasmic reticulum Ca2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes. Circ Res 1993 73 820 828
    • (1993) Circ Res , vol.73 , pp. 820-828
    • Hove-Madsen, L.1    Bers, D.M.2
  • 35
    • 33746861904 scopus 로고    scopus 로고
    • Sex-based transmural differences in cardiac repolarization and ionic-current properties in canine left ventricles
    • Xiao L, Zhang L, Han W, Wang Z, Nattel S, Sex-based transmural differences in cardiac repolarization and ionic-current properties in canine left ventricles. Am J Physiol Heart Circ Physiol 2006 291 H570 H580. doi: 10.1152/ajpheart.01288.2005
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H570-H580
    • Xiao, L.1    Zhang, L.2    Han, W.3    Wang, Z.4    Nattel, S.5
  • 37
    • 33746912380 scopus 로고    scopus 로고
    • Effect of estrogen on calcium-handling proteins, beta-adrenergic receptors, and function in rat heart
    • Chu SH, Goldspink P, Kowalski J, Beck J, Schwertz DW, Effect of estrogen on calcium-handling proteins, beta-adrenergic receptors, and function in rat heart. Life Sci 2006 79 1257 1267. doi: 10.1016/j.lfs.2006.03.037
    • (2006) Life Sci , vol.79 , pp. 1257-1267
    • Chu, S.H.1    Goldspink, P.2    Kowalski, J.3    Beck, J.4    Schwertz, D.W.5
  • 38
    • 4644291113 scopus 로고    scopus 로고
    • Sodium calcium exchange in the heart: Necessity or luxury?
    • Eisner DA, Sipido KR, Sodium calcium exchange in the heart: necessity or luxury? Circ Res 2004 95 549 551. doi: 10.1161/01.RES.0000143419.87518.9e
    • (2004) Circ Res , vol.95 , pp. 549-551
    • Eisner, D.A.1    Sipido, K.R.2
  • 39
    • 25444510359 scopus 로고    scopus 로고
    • Nontranscriptional regulation of cardiac repolarization currents by testosterone
    • Bai CX, Kurokawa J, Tamagawa M, Nakaya H, Furukawa T, Nontranscriptional regulation of cardiac repolarization currents by testosterone. Circulation 2005 112 1701 1710. doi: 10.1161/CIRCULATIONAHA.104.523217
    • (2005) Circulation , vol.112 , pp. 1701-1710
    • Bai, C.X.1    Kurokawa, J.2    Tamagawa, M.3    Nakaya, H.4    Furukawa, T.5
  • 40
    • 0030608780 scopus 로고    scopus 로고
    • Effects of 17beta-estradiol on action potentials and ionic currents in male rat ventricular myocytes
    • Berger F, Borchard U, Hafner D, Pütz I, Weis TM, Effects of 17beta-estradiol on action potentials and ionic currents in male rat ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol 1997 356 788 796
    • (1997) Naunyn Schmiedebergs Arch Pharmacol , vol.356 , pp. 788-796
    • Berger, F.1    Borchard, U.2    Hafner, D.3    Pütz, I.4    Weis, T.M.5
  • 41
    • 0032988406 scopus 로고    scopus 로고
    • Antiarrhythmic effect and its underlying ionic mechanism of 17beta-estradiol in cardiac myocytes
    • Nakajima T, Iwasawa K, Oonuma H, Morita T, Goto A, Wang Y, Hazama H, Antiarrhythmic effect and its underlying ionic mechanism of 17beta-estradiol in cardiac myocytes. Br J Pharmacol 1999 127 429 440. doi: 10.1038/sj.bjp.0702576
    • (1999) Br J Pharmacol , vol.127 , pp. 429-440
    • Nakajima, T.1    Iwasawa, K.2    Oonuma, H.3    Morita, T.4    Goto, A.5    Wang, Y.6    Hazama, H.7
  • 44
    • 84905252629 scopus 로고    scopus 로고
    • Sex differences in myosin heavy chain isoforms of human failing and nonfailing atria
    • Reiser PJ, Moravec CS, Sex differences in myosin heavy chain isoforms of human failing and nonfailing atria. Am J Physiol Heart Circ Physiol 2014 307 H265 H272. doi: 10.1152/ajpheart.00810.2013
    • (2014) Am J Physiol Heart Circ Physiol , vol.307 , pp. H265-H272
    • Reiser, P.J.1    Moravec, C.S.2
  • 45
    • 0034599128 scopus 로고    scopus 로고
    • Myosin heavy chain isoform expression in the failing and nonfailing human heart
    • Miyata S, Minobe W, Bristow MR, Leinwand LA, Myosin heavy chain isoform expression in the failing and nonfailing human heart. Circ Res 2000 86 386 390
    • (2000) Circ Res , vol.86 , pp. 386-390
    • Miyata, S.1    Minobe, W.2    Bristow, M.R.3    Leinwand, L.A.4
  • 48
    • 0021339867 scopus 로고
    • The effects of gonadectomy on left ventricular function and cardiac contractile proteins in male and female rats
    • Schaible TF, Malhotra A, Ciambrone G, Scheuer J, The effects of gonadectomy on left ventricular function and cardiac contractile proteins in male and female rats. Circ Res 1984 54 38 49
    • (1984) Circ Res , vol.54 , pp. 38-49
    • Schaible, T.F.1    Malhotra, A.2    Ciambrone, G.3    Scheuer, J.4
  • 49
    • 0029131129 scopus 로고
    • Steroid-hormone regulation of myosin subunit expression in smooth and cardiac muscle
    • Calovini T, Haase H, Morano I, Steroid-hormone regulation of myosin subunit expression in smooth and cardiac muscle. J Cell Biochem 1995 59 69 78. doi: 10.1002/jcb.240590109
    • (1995) J Cell Biochem , vol.59 , pp. 69-78
    • Calovini, T.1    Haase, H.2    Morano, I.3
  • 50
    • 0023189442 scopus 로고
    • Effects of gonadectomy and hormonal replacement on rat hearts
    • Scheuer J, Malhotra A, Schaible TF, Capasso J, Effects of gonadectomy and hormonal replacement on rat hearts. Circ Res 1987 61 12 19
    • (1987) Circ Res , vol.61 , pp. 12-19
    • Scheuer, J.1    Malhotra, A.2    Schaible, T.F.3    Capasso, J.4
  • 51
    • 0028314560 scopus 로고
    • Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium
    • Rosenkranz-Weiss P, Tomek RJ, Mathew J, Eghbali M, Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium. J Mol Cell Cardiol 1994 26 261 270
    • (1994) J Mol Cell Cardiol , vol.26 , pp. 261-270
    • Rosenkranz-Weiss, P.1    Tomek, R.J.2    Mathew, J.3    Eghbali, M.4
  • 52
    • 84876898162 scopus 로고    scopus 로고
    • Sexually dimorphic myofilament function and cardiac troponin i phosphospecies distribution in hypertrophic cardiomyopathy mice
    • McKee LA, Chen H, Regan JA, Behunin SM, Walker JW, Walker JS, Konhilas JP, Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice. Arch Biochem Biophys 2013 535 39 48. doi: 10.1016/j.abb.2012.12.023
    • (2013) Arch Biochem Biophys , vol.535 , pp. 39-48
    • McKee, L.A.1    Chen, H.2    Regan, J.A.3    Behunin, S.M.4    Walker, J.W.5    Walker, J.S.6    Konhilas, J.P.7
  • 53
    • 84875072973 scopus 로고    scopus 로고
    • Hormonal regulation of β-myosin heavy chain expression in the mouse left ventricle
    • Patrizio M, Musumeci M, Piccone A, Raggi C, Mattei E, Marano G, Hormonal regulation of β-myosin heavy chain expression in the mouse left ventricle. J Endocrinol 2013 216 287 296. doi: 10.1530/JOE-12-0201
    • (2013) J Endocrinol , vol.216 , pp. 287-296
    • Patrizio, M.1    Musumeci, M.2    Piccone, A.3    Raggi, C.4    Mattei, E.5    Marano, G.6
  • 56
    • 7444251178 scopus 로고    scopus 로고
    • Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts
    • Yan L, Ge H, Li H, Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts. J Mol Cell Cardiol 2004 37 921 929. doi: 10.1016/j.yjmcc.2004.06.012
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 921-929
    • Yan, L.1    Ge, H.2    Li, H.3
  • 57
    • 84921824794 scopus 로고    scopus 로고
    • Sexual dimorphism in the expression of mitochondria-related genes in rat heart at different ages
    • Vijay V, Han T, Moland CL, Kwekel JC, Fuscoe JC, Desai VG, Sexual dimorphism in the expression of mitochondria-related genes in rat heart at different ages. PLoS One 2015 10 e0117047. doi: 10.1371/journal.pone.0117047
    • (2015) PLoS One , vol.10 , pp. e0117047
    • Vijay, V.1    Han, T.2    Moland, C.L.3    Kwekel, J.C.4    Fuscoe, J.C.5    Desai, V.G.6
  • 58
    • 34247873129 scopus 로고    scopus 로고
    • Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage
    • Colom B, Oliver J, Roca P, Garcia-Palmer FJ, Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage. Cardiovasc Res 2007 74 456 465. doi: 10.1016/j.cardiores.2007.02.001
    • (2007) Cardiovasc Res , vol.74 , pp. 456-465
    • Colom, B.1    Oliver, J.2    Roca, P.3    Garcia-Palmer, F.J.4
  • 59
    • 77953811756 scopus 로고    scopus 로고
    • Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females
    • Lagranha CJ, Deschamps A, Aponte A, Steenbergen C, Murphy E, Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females. Circ Res 2010 106 1681 1691. doi: 10.1161/CIRCRESAHA.109.213645
    • (2010) Circ Res , vol.106 , pp. 1681-1691
    • Lagranha, C.J.1    Deschamps, A.2    Aponte, A.3    Steenbergen, C.4    Murphy, E.5
  • 60
    • 0033566952 scopus 로고    scopus 로고
    • 17 Beta-estradiol stimulates expression of endothelial and inducible NO synthase in rat myocardium in-vitro and in-vivo
    • Nuedling S, Kahlert S, Loebbert K, Doevendans PA, Meyer R, Vetter H, Grohé C, 17 Beta-estradiol stimulates expression of endothelial and inducible NO synthase in rat myocardium in-vitro and in-vivo. Cardiovasc Res 1999 43 666 674
    • (1999) Cardiovasc Res , vol.43 , pp. 666-674
    • Nuedling, S.1    Kahlert, S.2    Loebbert, K.3    Doevendans, P.A.4    Meyer, R.5    Vetter, H.6    Grohé, C.7
  • 61
    • 77956090193 scopus 로고    scopus 로고
    • Mitochondrial protein import: From proteomics to functional mechanisms
    • Schmidt O, Pfanner N, Meisinger C, Mitochondrial protein import: from proteomics to functional mechanisms. Nat Rev Mol Cell Biol 2010 11 655 667. doi: 10.1038/nrm2959
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 655-667
    • Schmidt, O.1    Pfanner, N.2    Meisinger, C.3
  • 62
    • 20444398494 scopus 로고    scopus 로고
    • Molecular and cellular basis of cardiovascular gender differences
    • Mendelsohn ME, Karas RH, Molecular and cellular basis of cardiovascular gender differences. Science 2005 308 1583 1587. doi: 10.1126/science.1112062
    • (2005) Science , vol.308 , pp. 1583-1587
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 63
    • 0023613947 scopus 로고
    • The "one and only" step model of estrogen action
    • Gorski J, Hansen JC, The "one and only" step model of estrogen action. Steroids 1987 49 461 475
    • (1987) Steroids , vol.49 , pp. 461-475
    • Gorski, J.1    Hansen, J.C.2
  • 64
    • 77950407928 scopus 로고    scopus 로고
    • Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling
    • 0317
    • Kang L, Zhang X, Xie Y, Tu Y, Wang D, Liu Z, Wang ZY, Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling. Mol Endocrinol 2010 24 709 721. doi: 10.1210/me.2009-0317
    • (2010) Mol Endocrinol , vol.24 , pp. 709-721
    • Kang, L.1    Zhang, X.2    Xie, Y.3    Tu, Y.4    Wang, D.5    Liu, Z.6    Wang, Z.Y.7
  • 65
    • 84901500355 scopus 로고    scopus 로고
    • Estrogen and the female heart
    • Knowlton AA, Korzick DH, Estrogen and the female heart. Mol Cell Endocrinol 2014 389 31 39. doi: 10.1016/j.mce.2014.01.002
    • (2014) Mol Cell Endocrinol , vol.389 , pp. 31-39
    • Knowlton, A.A.1    Korzick, D.H.2
  • 66
    • 84876128831 scopus 로고    scopus 로고
    • GPER: A novel target for non-genomic estrogen action in the cardiovascular system
    • Han G, Li F, Yu X, White RE, GPER: a novel target for non-genomic estrogen action in the cardiovascular system. Pharmacol Res 2013 71 53 60. doi: 10.1016/j.phrs.2013.02.008
    • (2013) Pharmacol Res , vol.71 , pp. 53-60
    • Han, G.1    Li, F.2    Yu, X.3    White, R.E.4
  • 67
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group
    • Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E, Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 1998 280 605 613
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3    Furberg, C.4    Herrington, D.5    Riggs, B.6    Vittinghoff, E.7
  • 68
    • 84907348536 scopus 로고    scopus 로고
    • Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: A randomized trial
    • Harman SM, Black DM, Naftolin F, Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial. Ann Intern Med 2014 161 249 260. doi: 10.7326/M14-0353
    • (2014) Ann Intern Med , vol.161 , pp. 249-260
    • Harman, S.M.1    Black, D.M.2    Naftolin, F.3
  • 69
    • 0025099451 scopus 로고
    • Steroid hormones and the cardiovascular system: Direct actions of estradiol, progesterone, testosterone, gluco- and mineralcorticoids, and soltriol [Vitamin D] on central nervous regulatory and peripheral tissues
    • Stumpf WE, Steroid hormones and the cardiovascular system: direct actions of estradiol, progesterone, testosterone, gluco- and mineralcorticoids, and soltriol [vitamin D] on central nervous regulatory and peripheral tissues. Experientia 1990 46 13 25
    • (1990) Experientia , vol.46 , pp. 13-25
    • Stumpf, W.E.1
  • 70
    • 77951218481 scopus 로고    scopus 로고
    • Influence of sex hormones and phytoestrogens on heart disease in men and women
    • Bhupathy P, Haines CD, Leinwand LA, Influence of sex hormones and phytoestrogens on heart disease in men and women. Womens Health (Lond Engl) 2010 6 77 95. doi: 10.2217/whe.09.80
    • (2010) Womens Health (Lond Engl) , vol.6 , pp. 77-95
    • Bhupathy, P.1    Haines, C.D.2    Leinwand, L.A.3
  • 71
    • 33746792472 scopus 로고    scopus 로고
    • Soy protein, isoflavones, and cardiovascular health: A summary of a statement for professionals from the American Heart Association nutrition committee
    • Sacks FM, Lichtenstein A, Van Horn L, Harris W, Kris-Etherton P, Winston M, Soy protein, isoflavones, and cardiovascular health: a summary of a statement for professionals from the american heart association nutrition committee. Arterioscler Thromb Vasc Biol 2006 26 1689 1692. doi: 10.1161/01.ATV.0000227471.00284.ef
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1689-1692
    • Sacks, F.M.1    Lichtenstein, A.2    Van Horn, L.3    Harris, W.4    Kris-Etherton, P.5    Winston, M.6
  • 72
    • 0037371577 scopus 로고    scopus 로고
    • Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes
    • Liew R, Williams JK, Collins P, MacLeod KT, Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes. J Pharmacol Exp Ther 2003 304 985 993. doi: 10.1124/jpet.102.042986
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 985-993
    • Liew, R.1    Williams, J.K.2    Collins, P.3    MacLeod, K.T.4
  • 75
    • 0020380035 scopus 로고
    • A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I Cycle frequency, length and vaginal cytology
    • Nelson JF, Felicio LS, Randall PK, Sims C, Finch CE, A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology. Biol Reprod 1982 27 327 339
    • (1982) Biol Reprod , vol.27 , pp. 327-339
    • Nelson, J.F.1    Felicio, L.S.2    Randall, P.K.3    Sims, C.4    Finch, C.E.5
  • 76
    • 0019451971 scopus 로고
    • Altered profiles of estradiol and progesterone associated with prolonged estrous cycles and persistent vaginal cornification in aging C57BL/6J mice
    • Nelson JF, Felicio LS, Osterburg HH, Finch CE, Altered profiles of estradiol and progesterone associated with prolonged estrous cycles and persistent vaginal cornification in aging C57BL/6J mice. Biol Reprod 1981 24 784 794
    • (1981) Biol Reprod , vol.24 , pp. 784-794
    • Nelson, J.F.1    Felicio, L.S.2    Osterburg, H.H.3    Finch, C.E.4
  • 77
    • 77954856291 scopus 로고    scopus 로고
    • Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography-tandem mass spectrometry
    • McNamara KM, Harwood DT, Simanainen U, Walters KA, Jimenez M, Handelsman DJ, Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography-tandem mass spectrometry. J Steroid Biochem Mol Biol 2010 121 611 618. doi: 10.1016/j.jsbmb.2010.02.001
    • (2010) J Steroid Biochem Mol Biol , vol.121 , pp. 611-618
    • McNamara, K.M.1    Harwood, D.T.2    Simanainen, U.3    Walters, K.A.4    Jimenez, M.5    Handelsman, D.J.6
  • 78
    • 24144437357 scopus 로고    scopus 로고
    • Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause
    • Mayer LP, Dyer CA, Eastgard RL, Hoyer PB, Banka CL, Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause. Arterioscler Thromb Vasc Biol 2005 25 1910 1916. doi: 10.1161/01.ATV.0000175767.46520.6a
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1910-1916
    • Mayer, L.P.1    Dyer, C.A.2    Eastgard, R.L.3    Hoyer, P.B.4    Banka, C.L.5
  • 79
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD, Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006 7 589 600. doi: 10.1038/nrm1983
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 80
    • 33846966331 scopus 로고    scopus 로고
    • Differences between pathological and physiological cardiac hypertrophy: Novel therapeutic strategies to treat heart failure
    • 1681.2007.04585.x
    • McMullen JR, Jennings GL, Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure. Clin Exp Pharmacol Physiol 2007 34 255 262. doi: 10.1111/j.1440-1681.2007.04585.x
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 255-262
    • McMullen, J.R.1    Jennings, G.L.2
  • 83
    • 0034711753 scopus 로고    scopus 로고
    • Essential hypertension. Part I: Definition and etiology
    • Carretero OA, Oparil S, Essential hypertension. Part I: definition and etiology. Circulation 2000 101 329 335
    • (2000) Circulation , vol.101 , pp. 329-335
    • Carretero, O.A.1    Oparil, S.2
  • 84
    • 84892478542 scopus 로고
    • Blood pressure readings of 75,258 university students
    • Boynton RE, Todd RL, Blood pressure readings of 75,258 university students. Arch Intern Med (Chic) 1947 80 454 462
    • (1947) Arch Intern Med (Chic) , vol.80 , pp. 454-462
    • Boynton, R.E.1    Todd, R.L.2
  • 85
    • 0017565967 scopus 로고
    • Blood pressure levels of persons 6-74 years. United States, 1971-1974
    • i-v
    • Roberts J, Maurer K, Blood pressure levels of persons 6-74 years. United States, 1971-1974. Vital Health Stat 11 1977 203 i-v, 1-103
    • (1977) Vital Health Stat , vol.11 , pp. 203
    • Roberts, J.1    Maurer, K.2
  • 86
    • 84892420254 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: Basis of sex differences in incidence and treatment response
    • Mair KM, Johansen AK, Wright AF, Wallace E, MacLean MR, Pulmonary arterial hypertension: basis of sex differences in incidence and treatment response. Br J Pharmacol 2014 171 567 579. doi: 10.1111/bph.12281
    • (2014) Br J Pharmacol , vol.171 , pp. 567-579
    • Mair, K.M.1    Johansen, A.K.2    Wright, A.F.3    Wallace, E.4    MacLean, M.R.5
  • 89
    • 0347418917 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and evidence from new hypertension trials
    • Jones DW, Hall JE, Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and evidence from new hypertension trials. Hypertension 2004 43 1 3. doi: 10.1161/01.HYP.0000110061.06674.ca
    • (2004) Hypertension , vol.43 , pp. 1-3
    • Jones, D.W.1    Hall, J.E.2
  • 90
    • 0011879431 scopus 로고
    • Definitions and characteristics of sodium sensitivity and blood pressure resistance
    • Weinberger MH, Miller JZ, Luft FC, Grim CE, Fineberg NS, Definitions and characteristics of sodium sensitivity and blood pressure resistance. Hypertension 1986 8 II127 II134
    • (1986) Hypertension , vol.8 , pp. II127-II134
    • Weinberger, M.H.1    Miller, J.Z.2    Luft, F.C.3    Grim, C.E.4    Fineberg, N.S.5
  • 91
    • 0029661428 scopus 로고    scopus 로고
    • P22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
    • Ushio-Fukai M, Zafari AM, Fukui T, Ishizaka N, Griendling KK, p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem 1996 271 23317 23321
    • (1996) J Biol Chem , vol.271 , pp. 23317-23321
    • Ushio-Fukai, M.1    Zafari, A.M.2    Fukui, T.3    Ishizaka, N.4    Griendling, K.K.5
  • 92
    • 5444230084 scopus 로고    scopus 로고
    • Female sex hormones, salt, and blood pressure regulation
    • Pechère-Bertschi A, Burnier M, Female sex hormones, salt, and blood pressure regulation. Am J Hypertens 2004 17 994 1001. doi: 10.1016/j.amjhyper.2004.08.009
    • (2004) Am J Hypertens , vol.17 , pp. 994-1001
    • Pechère-Bertschi, A.1    Burnier, M.2
  • 93
    • 0011910306 scopus 로고
    • Development of a strain of spontaneously hypertensive rats
    • Okamoto K, Aoki K, Development of a strain of spontaneously hypertensive rats. Jpn Circ J 1963 27 282 293
    • (1963) Jpn Circ J , vol.27 , pp. 282-293
    • Okamoto, K.1    Aoki, K.2
  • 94
    • 20144377218 scopus 로고    scopus 로고
    • Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
    • Hubner N, Wallace CA, Zimdahl H, Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet 2005 37 243 253. doi: 10.1038/ng1522
    • (2005) Nat Genet , vol.37 , pp. 243-253
    • Hubner, N.1    Wallace, C.A.2    Zimdahl, H.3
  • 95
    • 33750202275 scopus 로고    scopus 로고
    • The genetic dissection of essential hypertension
    • Cowley AW Jr, The genetic dissection of essential hypertension. Nat Rev Genet 2006 7 829 840. doi: 10.1038/nrg1967
    • (2006) Nat Rev Genet , vol.7 , pp. 829-840
    • Cowley, A.W.1
  • 96
    • 0031611277 scopus 로고    scopus 로고
    • Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats
    • Reckelhoff JF, Zhang H, Granger JP, Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats. Hypertension 1998 31 435 439
    • (1998) Hypertension , vol.31 , pp. 435-439
    • Reckelhoff, J.F.1    Zhang, H.2    Granger, J.P.3
  • 98
    • 33644800896 scopus 로고    scopus 로고
    • Cardiomyocyte function associated with hyperactivity and/or hypertension in genetic models of LV hypertrophy
    • Palmer BM, Chen Z, Lachapelle RR, Hendley ED, LeWinter MM, Cardiomyocyte function associated with hyperactivity and/or hypertension in genetic models of LV hypertrophy. Am J Physiol Heart Circ Physiol 2006 290 H463 H473. doi: 10.1152/ajpheart.00310.2005
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H463-H473
    • Palmer, B.M.1    Chen, Z.2    Lachapelle, R.R.3    Hendley, E.D.4    LeWinter, M.M.5
  • 99
    • 0032127809 scopus 로고    scopus 로고
    • Rat models of hypertension, cardiac hypertrophy and failure
    • Doggrell SA, Brown L, Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res 1998 39 89 105
    • (1998) Cardiovasc Res , vol.39 , pp. 89-105
    • Doggrell, S.A.1    Brown, L.2
  • 100
    • 84904297635 scopus 로고    scopus 로고
    • Female sex hormones protect against salt-sensitive hypertension but not essential hypertension
    • Brinson KN, Rafikova O, Sullivan JC, Female sex hormones protect against salt-sensitive hypertension but not essential hypertension. Am J Physiol Regul Integr Comp Physiol 2014 307 R149 R157. doi: 10.1152/ajpregu.00061.2014
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.307 , pp. R149-R157
    • Brinson, K.N.1    Rafikova, O.2    Sullivan, J.C.3
  • 102
    • 0033977726 scopus 로고    scopus 로고
    • Gender differences in development of hypertension in spontaneously hypertensive rats: Role of the renin-angiotensin system
    • Reckelhoff JF, Zhang H, Srivastava K, Gender differences in development of hypertension in spontaneously hypertensive rats: role of the renin-angiotensin system. Hypertension 2000 35 480 483
    • (2000) Hypertension , vol.35 , pp. 480-483
    • Reckelhoff, J.F.1    Zhang, H.2    Srivastava, K.3
  • 104
    • 84876295580 scopus 로고    scopus 로고
    • Sex differences in salt-sensitivity risk approximated from ambulatory blood pressure monitoring and mortality
    • b013e32835f29f4
    • Bursztyn M, Ben-Dov IZ, Sex differences in salt-sensitivity risk approximated from ambulatory blood pressure monitoring and mortality. J Hypertens 2013 31 900 905. doi: 10.1097/HJH.0b013e32835f29f4
    • (2013) J Hypertens , vol.31 , pp. 900-905
    • Bursztyn, M.1    Ben-Dov, I.Z.2
  • 105
    • 0021858418 scopus 로고
    • Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats
    • Rapp JP, Dene H, Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats. Hypertension 1985 7 340 349
    • (1985) Hypertension , vol.7 , pp. 340-349
    • Rapp, J.P.1    Dene, H.2
  • 107
    • 0033979882 scopus 로고    scopus 로고
    • Role of female sex hormones in the development and reversal of dahl hypertension
    • Hinojosa-Laborde C, Lange DL, Haywood JR, Role of female sex hormones in the development and reversal of dahl hypertension. Hypertension 2000 35 484 489
    • (2000) Hypertension , vol.35 , pp. 484-489
    • Hinojosa-Laborde, C.1    Lange, D.L.2    Haywood, J.R.3
  • 111
    • 0034979296 scopus 로고    scopus 로고
    • Gender-specific compensation for the lack of NO in the mediation of flow-induced arteriolar dilation
    • Wu Y, Huang A, Sun D, Falck JR, Koller A, Kaley G, Gender-specific compensation for the lack of NO in the mediation of flow-induced arteriolar dilation. Am J Physiol Heart Circ Physiol 2001 280 H2456 H2461
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , pp. H2456-H2461
    • Wu, Y.1    Huang, A.2    Sun, D.3    Falck, J.R.4    Koller, A.5    Kaley, G.6
  • 112
    • 0038082994 scopus 로고    scopus 로고
    • Gender-dependent response in blood pressure changes following the inhibition of nitric oxide synthase
    • Wang YR, Yen CH, Sun YF, Laun YT, Gender-dependent response in blood pressure changes following the inhibition of nitric oxide synthase. Chin J Physiol 2003 46 91 94
    • (2003) Chin J Physiol , vol.46 , pp. 91-94
    • Wang, Y.R.1    Yen, C.H.2    Sun, Y.F.3    Laun, Y.T.4
  • 115
    • 0032127132 scopus 로고    scopus 로고
    • Lessons from rat models of hypertension: From Goldblatt to genetic engineering
    • Pinto YM, Paul M, Ganten D, Lessons from rat models of hypertension: from Goldblatt to genetic engineering. Cardiovasc Res 1998 39 77 88
    • (1998) Cardiovasc Res , vol.39 , pp. 77-88
    • Pinto, Y.M.1    Paul, M.2    Ganten, D.3
  • 116
    • 57149133410 scopus 로고    scopus 로고
    • Heart failure after acute myocardial infarction: A lost battle in the war on heart failure?
    • Jhund PS, McMurray JJ, Heart failure after acute myocardial infarction: a lost battle in the war on heart failure? Circulation 2008 118 2019 2021. doi: 10.1161/CIRCULATIONAHA.108.813493
    • (2008) Circulation , vol.118 , pp. 2019-2021
    • Jhund, P.S.1    McMurray, J.J.2
  • 117
    • 84922381210 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2015 update: A report from the American Heart Association
    • American Heart Association Statistics Committee and Stroke Statistics Subcommittee American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Mozaffarian D, Benjamin EJ, Go AS, American Heart Association Statistics Committee and Stroke Statistics Subcommittee American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics-2015 update: a report from the American Heart Association. Circulation 2015 131 e29 322. doi: 10.1161/CIR.0000000000000152
    • (2015) Circulation , vol.131 , pp. e29-322
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 119
    • 84862796031 scopus 로고    scopus 로고
    • Age-specific gender differences in in-hospital mortality by type of acute myocardial infarction
    • Zhang Z, Fang J, Gillespie C, Wang G, Hong Y, Yoon PW, Age-specific gender differences in in-hospital mortality by type of acute myocardial infarction. Am J Cardiol 2012 109 1097 1103. doi: 10.1016/j.amjcard.2011.12.001
    • (2012) Am J Cardiol , vol.109 , pp. 1097-1103
    • Zhang, Z.1    Fang, J.2    Gillespie, C.3    Wang, G.4    Hong, Y.5    Yoon, P.W.6
  • 120
    • 0028095125 scopus 로고
    • Prognosis in myocardial infarction in relation to gender
    • Karlson BW, Herlitz J, Hartford M, Prognosis in myocardial infarction in relation to gender. Am Heart J 1994 128 477 483
    • (1994) Am Heart J , vol.128 , pp. 477-483
    • Karlson, B.W.1    Herlitz, J.2    Hartford, M.3
  • 121
    • 84883252000 scopus 로고    scopus 로고
    • Pathological ventricular remodeling: Therapies: Part 2 of 2
    • Xie M, Burchfield JS, Hill JA, Pathological ventricular remodeling: therapies: part 2 of 2. Circulation 2013 128 1021 1030. doi: 10.1161/CIRCULATIONAHA.113.001879
    • (2013) Circulation , vol.128 , pp. 1021-1030
    • Xie, M.1    Burchfield, J.S.2    Hill, J.A.3
  • 122
    • 0029797497 scopus 로고    scopus 로고
    • Cellular and ionic basis of arrhythmias in postinfarction remodeled ventricular myocardium
    • Qin D, Zhang ZH, Caref EB, Boutjdir M, Jain P, el-Sherif N, Cellular and ionic basis of arrhythmias in postinfarction remodeled ventricular myocardium. Circ Res 1996 79 461 473
    • (1996) Circ Res , vol.79 , pp. 461-473
    • Qin, D.1    Zhang, Z.H.2    Caref, E.B.3    Boutjdir, M.4    Jain, P.5    El-Sherif, N.6
  • 123
    • 0032979720 scopus 로고    scopus 로고
    • Electrophysiological remodeling in hypertrophy and heart failure
    • Tomaselli GF, Marbán E, Electrophysiological remodeling in hypertrophy and heart failure. Cardiovasc Res 1999 42 270 283
    • (1999) Cardiovasc Res , vol.42 , pp. 270-283
    • Tomaselli, G.F.1    Marbán, E.2
  • 125
    • 4344583643 scopus 로고    scopus 로고
    • Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice
    • Cavasin MA, Tao Z, Menon S, Yang XP, Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice. Life Sci 2004 75 2181 2192. doi: 10.1016/j.lfs.2004.04.024
    • (2004) Life Sci , vol.75 , pp. 2181-2192
    • Cavasin, M.A.1    Tao, Z.2    Menon, S.3    Yang, X.P.4
  • 126
    • 35349001680 scopus 로고    scopus 로고
    • Differences in inflammation, MMP activation and collagen damage account for gender difference in murine cardiac rupture following myocardial infarction
    • Fang L, Gao XM, Moore XL, Kiriazis H, Su Y, Ming Z, Lim YL, Dart AM, Du XJ, Differences in inflammation, MMP activation and collagen damage account for gender difference in murine cardiac rupture following myocardial infarction. J Mol Cell Cardiol 2007 43 535 544. doi: 10.1016/j.yjmcc.2007.06.011
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 535-544
    • Fang, L.1    Gao, X.M.2    Moore, X.L.3    Kiriazis, H.4    Su, Y.5    Ming, Z.6    Lim, Y.L.7    Dart, A.M.8    Du, X.J.9
  • 127
    • 77957245096 scopus 로고    scopus 로고
    • An association between gene expression and better survival in female mice following myocardial infarction
    • Chen Q, Williams R, Healy CL, Wright CD, Wu SC, O'Connell TD, An association between gene expression and better survival in female mice following myocardial infarction. J Mol Cell Cardiol 2010 49 801 811. doi: 10.1016/j.yjmcc.2010.08.002
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 801-811
    • Chen, Q.1    Williams, R.2    Healy, C.L.3    Wright, C.D.4    Wu, S.C.5    O'Connell, T.D.6
  • 128
    • 51149119097 scopus 로고    scopus 로고
    • Sex-related changes in cardiac function following myocardial infarction in mice
    • Shioura KM, Geenen DL, Goldspink PH, Sex-related changes in cardiac function following myocardial infarction in mice. Am J Physiol Regul Integr Comp Physiol 2008 295 R528 R534. doi: 10.1152/ajpregu.90342.2008
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295 , pp. R528-R534
    • Shioura, K.M.1    Geenen, D.L.2    Goldspink, P.H.3
  • 130
  • 131
  • 132
    • 80052505366 scopus 로고    scopus 로고
    • Post-myocardial infarction left ventricular myocyte remodeling: Are there gender differences in rats?
    • Chen YF, Redetzke RA, Sivertson RM, Coburn TS, Cypher LR, Gerdes AM, Post-myocardial infarction left ventricular myocyte remodeling: are there gender differences in rats? Cardiovasc Pathol 2011 20 e189 e195. doi: 10.1016/j.carpath.2010.09.007
    • (2011) Cardiovasc Pathol , vol.20 , pp. e189-e195
    • Chen, Y.F.1    Redetzke, R.A.2    Sivertson, R.M.3    Coburn, T.S.4    Cypher, L.R.5    Gerdes, A.M.6
  • 133
    • 84887398818 scopus 로고    scopus 로고
    • Structural composition of myocardial infarction scar in middle-aged male and female rats: Does sex matter?
    • Bogatyryov Y, Tomanek RJ, Dedkov EI, Structural composition of myocardial infarction scar in middle-aged male and female rats: does sex matter? J Histochem Cytochem 2013 61 833 848. doi: 10.1369/0022155413499794
    • (2013) J Histochem Cytochem , vol.61 , pp. 833-848
    • Bogatyryov, Y.1    Tomanek, R.J.2    Dedkov, E.I.3
  • 134
    • 84927727517 scopus 로고    scopus 로고
    • Coronary vessels and cardiac myocytes of middle-aged rats demonstrate regional sex-specific adaptation in response to postmyocardial infarction remodeling
    • Dedkov EI, Oak K, Christensen LP, Tomanek RJ, Coronary vessels and cardiac myocytes of middle-aged rats demonstrate regional sex-specific adaptation in response to postmyocardial infarction remodeling. Biol Sex Differ 2014 5 1. doi: 10.1186/2042-6410-5-1
    • (2014) Biol Sex Differ , vol.5 , pp. 1
    • Dedkov, E.I.1    Oak, K.2    Christensen, L.P.3    Tomanek, R.J.4
  • 135
    • 20144389505 scopus 로고    scopus 로고
    • Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction
    • Pelzer T, Loza PA, Hu K, Bayer B, Dienesch C, Calvillo L, Couse JF, Korach KS, Neyses L, Ertl G, Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction. Circulation 2005 111 1492 1498. doi: 10.1161/01.CIR.0000159262.18512.46
    • (2005) Circulation , vol.111 , pp. 1492-1498
    • Pelzer, T.1    Loza, P.A.2    Hu, K.3    Bayer, B.4    Dienesch, C.5    Calvillo, L.6    Couse, J.F.7    Korach, K.S.8    Neyses, L.9    Ertl, G.10
  • 137
    • 0031171415 scopus 로고    scopus 로고
    • Estrogen receptor function as revealed by knockout studies: Neuroendocrine and behavioral aspects
    • Rissman EF, Wersinger SR, Taylor JA, Lubahn DB, Estrogen receptor function as revealed by knockout studies: neuroendocrine and behavioral aspects. Horm Behav 1997 31 232 243. doi: 10.1006/hbeh.1997.1390
    • (1997) Horm Behav , vol.31 , pp. 232-243
    • Rissman, E.F.1    Wersinger, S.R.2    Taylor, J.A.3    Lubahn, D.B.4
  • 138
    • 84890023038 scopus 로고    scopus 로고
    • Estrogen modulates cardiac growth through an estrogen receptor α-dependent mechanism in healthy ovariectomized mice
    • Kararigas G, Nguyen BT, Jarry H, Estrogen modulates cardiac growth through an estrogen receptor α-dependent mechanism in healthy ovariectomized mice. Mol Cell Endocrinol 2014 382 909 914. doi: 10.1016/j.mce.2013.11.011
    • (2014) Mol Cell Endocrinol , vol.382 , pp. 909-914
    • Kararigas, G.1    Nguyen, B.T.2    Jarry, H.3
  • 142
    • 74149089676 scopus 로고    scopus 로고
    • 17beta-Estradiol decreases vulnerability to ventricular arrhythmias by preserving connexin43 protein in infarcted rats
    • Chen CC, Lin CC, Lee TM, 17beta-Estradiol decreases vulnerability to ventricular arrhythmias by preserving connexin43 protein in infarcted rats. Eur J Pharmacol 2010 629 73 81. doi: 10.1016/j.ejphar.2009.11.050
    • (2010) Eur J Pharmacol , vol.629 , pp. 73-81
    • Chen, C.C.1    Lin, C.C.2    Lee, T.M.3
  • 143
    • 0345700665 scopus 로고    scopus 로고
    • Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction
    • Cavasin MA, Sankey SS, Yu AL, Menon S, Yang XP, Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction. Am J Physiol Heart Circ Physiol 2003 284 H1560 H1569. doi: 10.1152/ajpheart.01087.2002
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. H1560-H1569
    • Cavasin, M.A.1    Sankey, S.S.2    Yu, A.L.3    Menon, S.4    Yang, X.P.5
  • 144
    • 74049129003 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor
    • Van Rooij E, Fielitz J, Sutherland LB, Thijssen VL, Crijns HJ, Dimaio MJ, Shelton J, De Windt LJ, Hill JA, Olson EN, Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor. Circ Res 2010 106 155 165. doi: 10.1161/CIRCRESAHA.109.207084
    • (2010) Circ Res , vol.106 , pp. 155-165
    • Van Rooij, E.1    Fielitz, J.2    Sutherland, L.B.3    Thijssen, V.L.4    Crijns, H.J.5    Dimaio, M.J.6    Shelton, J.7    De Windt, L.J.8    Hill, J.A.9    Olson, E.N.10
  • 146
    • 0036073044 scopus 로고    scopus 로고
    • Ca(2+) loading and adrenergic stimulation reveal male/female differences in susceptibility to ischemia-reperfusion injury
    • Cross HR, Murphy E, Steenbergen C, Ca(2+) loading and adrenergic stimulation reveal male/female differences in susceptibility to ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 2002 283 H481 H489. doi: 10.1152/ajpheart.00790.2001
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H481-H489
    • Cross, H.R.1    Murphy, E.2    Steenbergen, C.3
  • 147
    • 0032576615 scopus 로고    scopus 로고
    • Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice
    • Cross HR, Lu L, Steenbergen C, Philipson KD, Murphy E, Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice. Circ Res 1998 83 1215 1223
    • (1998) Circ Res , vol.83 , pp. 1215-1223
    • Cross, H.R.1    Lu, L.2    Steenbergen, C.3    Philipson, K.D.4    Murphy, E.5
  • 148
    • 33646813330 scopus 로고    scopus 로고
    • Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury
    • Sun J, Picht E, Ginsburg KS, Bers DM, Steenbergen C, Murphy E, Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury. Circ Res 2006 98 403 411. doi: 10.1161/01.RES.0000202707.79018.0a
    • (2006) Circ Res , vol.98 , pp. 403-411
    • Sun, J.1    Picht, E.2    Ginsburg, K.S.3    Bers, D.M.4    Steenbergen, C.5    Murphy, E.6
  • 149
    • 4444315931 scopus 로고    scopus 로고
    • Male/female differences in intracellular Na+ regulation during ischemia/reperfusion in mouse heart
    • Imahashi K, London RE, Steenbergen C, Murphy E, Male/female differences in intracellular Na+ regulation during ischemia/reperfusion in mouse heart. J Mol Cell Cardiol 2004 37 747 753. doi: 10.1016/j.yjmcc.2004.06.010
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 747-753
    • Imahashi, K.1    London, R.E.2    Steenbergen, C.3    Murphy, E.4
  • 152
    • 33744942091 scopus 로고    scopus 로고
    • Sex differences in myocardial infarct size are abolished by sarcolemmal KATP channel blockade in rat
    • Johnson MS, Moore RL, Brown DA, Sex differences in myocardial infarct size are abolished by sarcolemmal KATP channel blockade in rat. Am J Physiol Heart Circ Physiol 2006 290 H2644 H2647. doi: 10.1152/ajpheart.01291.2005
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H2644-H2647
    • Johnson, M.S.1    Moore, R.L.2    Brown, D.A.3
  • 153
    • 17844377994 scopus 로고    scopus 로고
    • Susceptibility of the heart to ischaemia-reperfusion injury and exercise-induced cardioprotection are sex-dependent in the rat
    • Brown DA, Lynch JM, Armstrong CJ, Caruso NM, Ehlers LB, Johnson MS, Moore RL, Susceptibility of the heart to ischaemia-reperfusion injury and exercise-induced cardioprotection are sex-dependent in the rat. J Physiol 2005 564 619 630. doi: 10.1113/jphysiol.2004.081323
    • (2005) J Physiol , vol.564 , pp. 619-630
    • Brown, D.A.1    Lynch, J.M.2    Armstrong, C.J.3    Caruso, N.M.4    Ehlers, L.B.5    Johnson, M.S.6    Moore, R.L.7
  • 154
    • 12144265945 scopus 로고    scopus 로고
    • Sex differences in the myocardial inflammatory response to ischemia-reperfusion injury
    • Wang M, Baker L, Tsai BM, Meldrum KK, Meldrum DR, Sex differences in the myocardial inflammatory response to ischemia-reperfusion injury. Am J Physiol Endocrinol Metab 2005 288 E321 E326. doi: 10.1152/ajpendo.00278.2004
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E321-E326
    • Wang, M.1    Baker, L.2    Tsai, B.M.3    Meldrum, K.K.4    Meldrum, D.R.5
  • 155
    • 0035940388 scopus 로고    scopus 로고
    • Gender influences [Ca(2+)](i) during metabolic inhibition in myocytes overexpressing the Na(+)-Ca(2+) exchanger
    • Sugishita K, Su Z, Li F, Philipson KD, Barry WH, Gender influences [Ca(2+)](i) during metabolic inhibition in myocytes overexpressing the Na(+)-Ca(2+) exchanger. Circulation 2001 104 2101 2106
    • (2001) Circulation , vol.104 , pp. 2101-2106
    • Sugishita, K.1    Su, Z.2    Li, F.3    Philipson, K.D.4    Barry, W.H.5
  • 156
    • 77951499165 scopus 로고    scopus 로고
    • Female adult mouse cardiomyocytes are protected against oxidative stress
    • Wang F, He Q, Sun Y, Dai X, Yang XP, Female adult mouse cardiomyocytes are protected against oxidative stress. Hypertension 2010 55 1172 1178. doi: 10.1161/HYPERTENSIONAHA.110.150839
    • (2010) Hypertension , vol.55 , pp. 1172-1178
    • Wang, F.1    He, Q.2    Sun, Y.3    Dai, X.4    Yang, X.P.5
  • 157
    • 35848931483 scopus 로고    scopus 로고
    • Cardioprotection in females: A role for nitric oxide and altered gene expression
    • Murphy E, Steenbergen C, Cardioprotection in females: a role for nitric oxide and altered gene expression. Heart Fail Rev 2007 12 293 300. doi: 10.1007/s10741-007-9035-0
    • (2007) Heart Fail Rev , vol.12 , pp. 293-300
    • Murphy, E.1    Steenbergen, C.2
  • 159
    • 77649342305 scopus 로고    scopus 로고
    • Molecular targets and regulators of cardiac hypertrophy
    • Rohini A, Agrawal N, Koyani CN, Singh R, Molecular targets and regulators of cardiac hypertrophy. Pharmacol Res 2010 61 269 280. doi: 10.1016/j.phrs.2009.11.012
    • (2010) Pharmacol Res , vol.61 , pp. 269-280
    • Rohini, A.1    Agrawal, N.2    Koyani, C.N.3    Singh, R.4
  • 162
    • 0033493841 scopus 로고    scopus 로고
    • Hypertension: An important precursor of heart failure
    • Himmelmann A, Hypertension: an important precursor of heart failure. Blood Press 1999 8 253 260
    • (1999) Blood Press , vol.8 , pp. 253-260
    • Himmelmann, A.1
  • 164
    • 77953656472 scopus 로고    scopus 로고
    • Small animal models of heart failure: Development of novel therapies, past and present
    • Patten RD, Hall-Porter MR, Small animal models of heart failure: development of novel therapies, past and present. Circ Heart Fail 2009 2 138 144. doi: 10.1161/CIRCHEARTFAILURE.108.839761
    • (2009) Circ Heart Fail , vol.2 , pp. 138-144
    • Patten, R.D.1    Hall-Porter, M.R.2
  • 165
    • 0032192120 scopus 로고    scopus 로고
    • Hypertrophic remodeling: Gender differences in the early response to left ventricular pressure overload
    • Douglas PS, Katz SE, Weinberg EO, Chen MH, Bishop SP, Lorell BH, Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. J Am Coll Cardiol 1998 32 1118 1125
    • (1998) J Am Coll Cardiol , vol.32 , pp. 1118-1125
    • Douglas, P.S.1    Katz, S.E.2    Weinberg, E.O.3    Chen, M.H.4    Bishop, S.P.5    Lorell, B.H.6
  • 169
    • 84897511874 scopus 로고    scopus 로고
    • Gender-specific potential inhibitory role of Ca2+/calmodulin dependent protein kinase phosphatase (CaMKP) in pressure-overloaded mouse heart
    • Prévilon M, Pezet M, Vinet L, Mercadier JJ, Rouet-Benzineb P, Gender-specific potential inhibitory role of Ca2+/calmodulin dependent protein kinase phosphatase (CaMKP) in pressure-overloaded mouse heart. PLoS One 2014 9 e90822. doi: 10.1371/journal.pone.0090822
    • (2014) PLoS One , vol.9 , pp. e90822
    • Prévilon, M.1    Pezet, M.2    Vinet, L.3    Mercadier, J.J.4    Rouet-Benzineb, P.5
  • 172
    • 41149178733 scopus 로고    scopus 로고
    • 17 Beta-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload
    • Patten RD, Pourati I, Aronovitz MJ, Alsheikh-Ali A, Eder S, Force T, Mendelsohn ME, Karas RH, 17 Beta-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload. J Card Fail 2008 14 245 253. doi: 10.1016/j.cardfail.2007.10.024
    • (2008) J Card Fail , vol.14 , pp. 245-253
    • Patten, R.D.1    Pourati, I.2    Aronovitz, M.J.3    Alsheikh-Ali, A.4    Eder, S.5    Force, T.6    Mendelsohn, M.E.7    Karas, R.H.8
  • 177
    • 36148970420 scopus 로고    scopus 로고
    • Effects of sex differences on constitutive nitric oxide synthase expression and activity in response to pressure overload in rats
    • Loyer X, Oliviero P, Damy T, Robidel E, Marotte F, Heymes C, Samuel JL, Effects of sex differences on constitutive nitric oxide synthase expression and activity in response to pressure overload in rats. Am J Physiol Heart Circ Physiol 2007 293 H2650 H2658. doi: 10.1152/ajpheart.00883.2007
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H2650-H2658
    • Loyer, X.1    Oliviero, P.2    Damy, T.3    Robidel, E.4    Marotte, F.5    Heymes, C.6    Samuel, J.L.7
  • 178
    • 0034713820 scopus 로고    scopus 로고
    • Left ventricular hypertrophy: Pathogenesis, detection, and prognosis
    • Lorell BH, Carabello BA, Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 2000 102 470 479
    • (2000) Circulation , vol.102 , pp. 470-479
    • Lorell, B.H.1    Carabello, B.A.2
  • 179
    • 0036097942 scopus 로고    scopus 로고
    • Gender differences in cardiac remodeling secondary to chronic volume overload
    • Gardner JD, Brower GL, Janicki JS, Gender differences in cardiac remodeling secondary to chronic volume overload. J Card Fail 2002 8 101 107
    • (2002) J Card Fail , vol.8 , pp. 101-107
    • Gardner, J.D.1    Brower, G.L.2    Janicki, J.S.3
  • 180
    • 77951665428 scopus 로고    scopus 로고
    • Gender differences in cardiac dysfunction and remodeling due to volume overload
    • Dent MR, Tappia PS, Dhalla NS, Gender differences in cardiac dysfunction and remodeling due to volume overload. J Card Fail 2010 16 439 449. doi: 10.1016/j.cardfail.2009.12.017
    • (2010) J Card Fail , vol.16 , pp. 439-449
    • Dent, M.R.1    Tappia, P.S.2    Dhalla, N.S.3
  • 181
    • 77951666900 scopus 로고    scopus 로고
    • Gender differences in apoptotic signaling in heart failure due to volume overload
    • Dent MR, Tappia PS, Dhalla NS, Gender differences in apoptotic signaling in heart failure due to volume overload. Apoptosis 2010 15 499 510. doi: 10.1007/s10495-009-0441-8
    • (2010) Apoptosis , vol.15 , pp. 499-510
    • Dent, M.R.1    Tappia, P.S.2    Dhalla, N.S.3
  • 183
    • 78049289519 scopus 로고    scopus 로고
    • Gender differences in β-adrenoceptor system in cardiac hypertrophy due to arteriovenous fistula
    • Dent MR, Tappia PS, Dhalla NS, Gender differences in β-adrenoceptor system in cardiac hypertrophy due to arteriovenous fistula. J Cell Physiol 2011 226 181 186. doi: 10.1002/jcp.22321
    • (2011) J Cell Physiol , vol.226 , pp. 181-186
    • Dent, M.R.1    Tappia, P.S.2    Dhalla, N.S.3
  • 184
    • 84865405832 scopus 로고    scopus 로고
    • Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner
    • 1353
    • Haines CD, Harvey PA, Leinwand LA, Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner. Endocrinology 2012 153 4480 4490. doi: 10.1210/en.2012-1353
    • (2012) Endocrinology , vol.153 , pp. 4480-4490
    • Haines, C.D.1    Harvey, P.A.2    Leinwand, L.A.3
  • 189
    • 0033625214 scopus 로고    scopus 로고
    • Enhanced responses to 17beta-estradiol in rat hearts treated with isoproterenol: Involvement of a cyclic AMP-dependent pathway
    • Li HY, Bian JS, Kwan YW, Wong TM, Enhanced responses to 17beta-estradiol in rat hearts treated with isoproterenol: involvement of a cyclic AMP-dependent pathway. J Pharmacol Exp Ther 2000 293 592 598
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 592-598
    • Li, H.Y.1    Bian, J.S.2    Kwan, Y.W.3    Wong, T.M.4
  • 190
    • 17844404538 scopus 로고    scopus 로고
    • Increased PKA activity and its influence on isoprenaline-stimulated L-type Ca2+ channels in the heart from ovariectomized rats
    • Kam KW, Kravtsov GM, Liu J, Wong TM, Increased PKA activity and its influence on isoprenaline-stimulated L-type Ca2+ channels in the heart from ovariectomized rats. Br J Pharmacol 2005 144 972 981. doi: 10.1038/sj.bjp.0706123
    • (2005) Br J Pharmacol , vol.144 , pp. 972-981
    • Kam, K.W.1    Kravtsov, G.M.2    Liu, J.3    Wong, T.M.4
  • 191
    • 49749130437 scopus 로고    scopus 로고
    • Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia-reperfusion
    • Wu Q, Zhao Z, Sun H, Hao YL, Yan CD, Gu SL, Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia-reperfusion. Exp Physiol 2008 93 1034 1043. doi: 10.1113/expphysiol.2007.041939
    • (2008) Exp Physiol , vol.93 , pp. 1034-1043
    • Wu, Q.1    Zhao, Z.2    Sun, H.3    Hao, Y.L.4    Yan, C.D.5    Gu, S.L.6
  • 192
    • 46349084173 scopus 로고    scopus 로고
    • Estrogen inhibits cardiac hypertrophy: Role of estrogen receptor-beta to inhibit calcineurin
    • 0133
    • Pedram A, Razandi M, Lubahn D, Liu J, Vannan M, Levin ER, Estrogen inhibits cardiac hypertrophy: role of estrogen receptor-beta to inhibit calcineurin. Endocrinology 2008 149 3361 3369. doi: 10.1210/en.2008-0133
    • (2008) Endocrinology , vol.149 , pp. 3361-3369
    • Pedram, A.1    Razandi, M.2    Lubahn, D.3    Liu, J.4    Vannan, M.5    Levin, E.R.6
  • 193
    • 0034042102 scopus 로고    scopus 로고
    • Animal models of hypertrophic cardiomyopathy
    • Maass A, Leinwand LA, Animal models of hypertrophic cardiomyopathy. Curr Opin Cardiol 2000 15 189 196
    • (2000) Curr Opin Cardiol , vol.15 , pp. 189-196
    • Maass, A.1    Leinwand, L.A.2
  • 196
    • 33846997582 scopus 로고    scopus 로고
    • Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males
    • Luckey SW, Mansoori J, Fair K, Antos CL, Olson EN, Leinwand LA, Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males. Am J Physiol Heart Circ Physiol 2007 292 H838 H845. doi: 10.1152/ajpheart.00615.2006
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H838-H845
    • Luckey, S.W.1    Mansoori, J.2    Fair, K.3    Antos, C.L.4    Olson, E.N.5    Leinwand, L.A.6
  • 197
    • 5644261183 scopus 로고    scopus 로고
    • Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T
    • Maass AH, Ikeda K, Oberdorf-Maass S, Maier SK, Leinwand LA, Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. Circulation 2004 110 2102 2109. doi: 10.1161/01.CIR.0000144460.84795.E3
    • (2004) Circulation , vol.110 , pp. 2102-2109
    • Maass, A.H.1    Ikeda, K.2    Oberdorf-Maass, S.3    Maier, S.K.4    Leinwand, L.A.5
  • 198
    • 84920169941 scopus 로고    scopus 로고
    • 17β-estradiol prevents cardiac diastolic dysfunction by stimulating mitochondrial function: A preclinical study in a mouse model of a human hypertrophic cardiomyopathy mutation
    • Chen Y, Zhang Z, Hu F, Yang W, Yuan J, Cui J, Hao S, Hu J, Zhou Y, Qiao S, 17β-estradiol prevents cardiac diastolic dysfunction by stimulating mitochondrial function: a preclinical study in a mouse model of a human hypertrophic cardiomyopathy mutation. J Steroid Biochem Mol Biol 2015 147 92 102. doi: 10.1016/j.jsbmb.2014.12.011
    • (2015) J Steroid Biochem Mol Biol , vol.147 , pp. 92-102
    • Chen, Y.1    Zhang, Z.2    Hu, F.3    Yang, W.4    Yuan, J.5    Cui, J.6    Hao, S.7    Hu, J.8    Zhou, Y.9    Qiao, S.10
  • 200
    • 0036796263 scopus 로고    scopus 로고
    • Phenotypic diversity in hypertrophic cardiomyopathy
    • Arad M, Seidman JG, Seidman CE, Phenotypic diversity in hypertrophic cardiomyopathy. Hum Mol Genet 2002 11 2499 2506
    • (2002) Hum Mol Genet , vol.11 , pp. 2499-2506
    • Arad, M.1    Seidman, J.G.2    Seidman, C.E.3
  • 201
    • 78049424265 scopus 로고    scopus 로고
    • Gender-specific differences in the clinical features of hypertrophic cardiomyopathy in a community-based Japanese population: Results from Kochi RYOMA study
    • Kubo T, Kitaoka H, Okawa M, Hirota T, Hayato K, Yamasaki N, Matsumura Y, Yabe T, Doi YL, Gender-specific differences in the clinical features of hypertrophic cardiomyopathy in a community-based Japanese population: results from Kochi RYOMA study. J Cardiol 2010 56 314 319. doi: 10.1016/j.jjcc.2010.07.004
    • (2010) J Cardiol , vol.56 , pp. 314-319
    • Kubo, T.1    Kitaoka, H.2    Okawa, M.3    Hirota, T.4    Hayato, K.5    Yamasaki, N.6    Matsumura, Y.7    Yabe, T.8    Doi, Y.L.9


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