Gender Differences in Cardiac Dysfunction and Remodeling due to Volume Overload

Journal of Cardiac Failure

Volumn 16, Issue 5, 2010, Pages 439-449

  Dent, Melissa R ^a   Tappia, Paramjit S ^b   Dhalla, Naranjan S ^a  

^a ST BONIFACE GENERAL HOSPITAL RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Arteriovenous shunt; estrogen therapy; heart dysfunction; sex differences; ventricular remodeling

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; CATECHOLAMINE; DIPEPTIDYL CARBOXYPEPTIDASE; ESTRADIOL; ESTROGEN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOVENOUS SHUNT; ARTICLE; CATECHOLAMINE BLOOD LEVEL; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FEMALE; GENE EXPRESSION; HEART CONTRACTION; HEART DISEASE; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART OUTPUT; HEART VENTRICLE OVERLOAD; HEART VENTRICLE REMODELING; HEMODYNAMICS; MALE; MUSCLE MASS; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

ACETYLCHOLINESTERASE; ANIMALS; ARTERIOVENOUS SHUNT, SURGICAL; BIOLOGICAL MARKERS; BLOOD VOLUME; CARDIAC OUTPUT; CATECHOLAMINES; ESTROGENS; FEMALE; HEART FAILURE; HEART VENTRICLES; HEMODYNAMICS; HYPERTROPHY, LEFT VENTRICULAR; MALE; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RENIN-ANGIOTENSIN SYSTEM; RISK FACTORS; RNA, MESSENGER; SEX FACTORS; VENTRICULAR REMODELING; WATER INTOXICATION; WATER-ELECTROLYTE BALANCE;

EID: 77951665428     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2009.12.017     Document Type: Article

References (50)

1. Hasenfuss G. Animal models of human cardiovascular disease, heart failure and hypertrophy. Cardiovasc Res 39 (1998) 60-76
2. Hunter J.J., and Chien K.R. Signaling pathways for cardiac hypertrophy and failure. N Engl J Med 341 (1999) 1276-1283
3. Safar M.E., and Smulyan H. Hypertension in women. Am J Hypertens 17 (2004) 82-87
4. Regitz-Zagrosek V., and Lehmkuhl E. Heart failure and its treatment in women: role of hypertension, diabetes and estrogen. Herz 30 (2005) 356-367
5. Bello N., and Mosca L. Epidemiology of coronary heart disease in Women. Prog Cardiovasc Dis 4 (2004) 287-295
6. Hoppe B.L., and Hermann D.D. Sex differences in the causes and natural history of heart failure. Curr Cardiol Rep 5 (2003) 193-199
7. Jessup M., and Pina I.L. Is it important to examine gender differences in the epidemiology and outcome of severe heart failure?. J Thor Cardiovasc Surg 127 (2004) 1247-1252
8. Stromberg A., and Martensson J. Gender differences in patients with heart failure. Eur J Cardiovasc Nurs 2 (2003) 7-18
9. Schonfelder G. The biological impact of estrogens on gender differences in congestive heart failure. Cardiovasc Res 67 (2005) 573-574
10. Biondi-Zoccai G.G.L., Baldi A., Biasucci L.M., and Abbate A. Female gender, myocardial remodeling and cardiac failure: are women protected from increased myocardiocyte apoptosis?. Ital Heart J 5 (2004) 498-504
11. Douglas P.S., Katz S.E., Weinberg E.O., Chen M.H., Bishop S.P., and Lorell B.H. Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. J Am Coll Cardiol 32 (1998) 1118-1125
12. Skavdahl M., Steenbergen C., Clark J., Myers P., Demianenko T., Mao L., et al. Estrogen receptor-β mediates male-female differences in the development of pressure overload hypertrophy. Am J Physiol Heart Circ Physiol 288 (2005) H469-H476
13. Litwin S.E., Katz S.E., Litwin C.M., Morgan J.P., and Douglas P.S. Gender differences in postinfarction left ventricular remodeling. Cardiology 91 (1999) 173-183
14. Alyono D., Ring W.S., Anderson M.R., and Anderson R.W. Left ventricular adaptation to volume overload from large aortocaval fistula. Surgery 96 (1984) 360-367
15. Flaim S.F., Minteer W.J., Nellis S.H., and Clark D.P. Chronic arteriovenous shunt: evaluation of a model for heart failure in rat. Am J Physiol Heart Circ Physiol 236 (1979) H698-H704
16. Flaim S.F., Minteer W.J., and Zelis R. Acute effects of arterio-venous shunt on cardiovascular hemodynamics in rat. Pflügers Arch 385 (1980) 203-209
17. Gerdes A.M., Clark L.C., and Capasso J.M. Regression of cardiac hypertrophy after closing an aortocaval fistula in rats. Am J Physiol Heart Circ Physiol 268 (1995) H2345-H2351
18. Hatt P.Y., Rakusan K., Gastineau P., Laplace M., and Cluzeaud F. Aorto-caval fistula in the rat. An experimental model of heart volume overloading. Basic Res Cardiol 75 (1980) 105-108
19. Huang M., Hester R.L., and Guyton A.C. Hemodynamic changes in rats after opening an arteriovenous fistula. Am J Physiol Heart Circ Physiol 262 (1992) H846-H851
20. Liu Z., Hilbelink D.R., Crockett W.B., and Gerdes A.M. Regional changes in hemodynamics and cardiac myocyte size in rats with aortocaval fistulas. 1. Developing and established hypertrophy. Circ Res 69 (1991) 52-58
21. Liu Z., Hilbelink D.R., and Gerdes A.M. Regional changes in hemodynamics and cardiac myocyte size in rats with aortocaval fistulas. 2. Long-term effects. Circ Res 69 (1991) 59-65
22. Wang X., Ren B., Liu S., Sentex E., Tappia P.S., and Dhalla N.S. Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat. J Appl Physiol 94 (2003) 752-763
23. Gardner J.D., Brower G.L., and Janicki J.S. Gender differences in cardiac remodeling secondary to volume overload. J Card Fail 8 (2002) 101-107
24. Brower G.L., Gardner J.D., and Janicki J.S. Gender mediated cardiac protection from adverse ventricular remodeling is abolished by ovariectomy. Mol Cell Biochem 251 (2003) 89-95
25. Brower G.L., and Janicki J.S. Contribution of ventricular remodeling to pathogenesis of heart failure in rats. Am J Physiol Heart Circ Physiol 280 (2001) H674-H683
26. Dent M.R., Das S., and Dhalla N.S. Alterations in both death and survival signals for apoptosis in heart failure due to volume overload. J Mol Cell Cardiol 43 (2007) 726-732
27. Nekooeian A.A., and Pang C.C.Y. Effects of estrogen on venous function in rats with chronic heart failure. Am J Physiol Heart Circ Physiol 278 (2000) H1941-H1947
28. Yang X.P., Liu Y.H., Rhaleb N.E., Kurihara N., Kim H.E., and Carretero O.A. Echocardiographic assessment of cardiac function in conscious and anesthetized mice. Am J Physiol 277 (1999) H1967-H1974
29. Dent M.R., Dhalla N.S., and Tappia P.S. Phospholipase C gene expression, protein contents and activities in cardiac hypertrophy and heart failure due to volume overload. Am J Physiol Heart Circ Physiol 287 (2004) H719-H727
30. Sethi R., Adameova A., Dhalla K.S., Khan M., Elimban V., and Dhalla N.S. Modification of epinephrine-induced arrhythmias by N-acteyl-L-cysteine and vitamin E. J Cardiovasc Pharmacol Therap 14 (2009) 134-142
31. Grossman W., Jones D., and McLaurin L.P. Wall stress and patterns of hypertrophy in human left ventricle. J Clin Invest 56 (1975) 56-64
32. Rosano G.M., Sarrel P.M., Poole-Wilson P.A., and Collins P. Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet 342 (1993) 133-136
33. Huang A., Sun D., Koller A., and Kaley G. Gender difference in flow-induced dilation and regulation of shear stress: role of estrogen and nitric oxide. Am J Physiol Regulatory Integrative Comp Physiol 275 (1998) R1571-R1577
34. Briest W., Homagk L., Rabler B., Ziegelhoffer-Mihalovicova B., Meier H., Tannapfel A., et al. Norepinephrine-induced changes in cardiac transforming growth factor-β isoforms expression pattern of female and male rats. Hypertens 44 (2004) 410-418
35. Dunlay S.M., Weston S.A., Redfield M.M., Killian J.M., and Roger V.L. Tumor necrosis factor-α and mortality in heart failure: a community study. Circulation 118 (2008) 625-631
36. Rosenkranz-Weiss P., Tomek R.J., Matthew J., and Eghbali M. Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium. J Mol Cell Cardiol 26 (1994) 261-270
37. Modena M.G., Molinari R., Muia Jr. N., Castelli A., Pala F., and Rossi R. Double-blind randomized placebo-controlled study of transdermal estrogen replacement therapy on hypertensive postmenopausal women. Am J Hypertens 12 (1999) 1000-1008
38. Rossouw J.E., Anderson G.L., Prentice R.L., LaCroix A.Z., Kooperberg C., Stefanick M.L., et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. J Am Med Assoc 288 (2002) 221-232
39. Rossouw J.E., Prentice R.L., Manson J.E., Wu L., Barad D., Barnabei V.M., et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. J Am Med Assoc 297 (2007) 1465-1477
40. Mendelsohn M.E., and Karas R.H. The protective effects of estrogen on the cardiovascular system. N Engl J Med 340 (1999) 1801-1811
41. Nordmeyer J., Eder S., Mahmoodzadeh S., Martus P., Fielitz J., Bass J., et al. Upregulation of myocardial estrogen receptors in human aortic stenosis. Circulation 110 (2004) 3270-3275
42. Grohe C., Kahlert S., Lobbert K., and Vetter H. Expression of oestrogen receptor α and β in rat heart: role of local oestrogen synthesis. J Endocrinol 156 (1998) R1-R7
43. Mahmoodzadeh S., Eder S., Nordmeyer J., Ehler E., Huber O., Martus P., et al. Estrogen receptor α up-regulation and redistribution in human heart failure. FASEB J 20 (2006) 926-934
44. Donaldson C., Eder S., Baker C., Aronovitz M.J., Weiss A.D., Hall-Porter M., et al. Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation. Circ Res 104 (2009) 265-275
45. Lind J.M., Chiu C., Ingles J., Yeates L., Humphries S.E., Heather A.K., et al. Sex hormone receptor gene variation associated with phenotype in male hypertrophic cardiomyopathy patients. J Mol Cell Cardiol 45 (2008) 217-222
46. Gardner J.D., Brower G.L., and Janicki J.S. Effects of dietary phytoestrogens on cardiac remodeling secondary to chronic volume overload in female rats. J Appl Physiol 99 (2005) 1378-1383
47. Drolet M.C., Lachance D., Plante E., Roussel E., Couet J., and Arsenault M. Gender-related differences in left ventricular remodeling in chronic severe aortic valve regurgitation in rats. J Heart Valve Dis 15 (2006) 345-351
48. Patten R.D., Pourati I., Aronovitz M.J., Alsheikh-Ali A., Eder S., Force T., et al. 17 β-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload. J Card Fail 14 (2008) 245-253
49. Cavasin M.A., Sankey S.S., Yu A.L., Menon S., and Yang X.P. Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction. Am J Physiol Heart Circ Physiol 284 (2003) H1560-H1569
50. van Eickels M., Grohe C., Cleutjens J.P., Janssen B.J., Wellens H.J., and Doevendans P.A. 17 β-estradiol attenuates the development of pressure-overload hypertrophy. Circulation 104 (2001) 1419-1423