Aging reduces the efficacy of estrogen substitution to attenuate cardiac hypertrophy in female spontaneously hypertensive rats

Hypertension

Volumn 48, Issue 4, 2006, Pages 579-586

  Jazbutyte, Virginija ^a   Hu, Kai ^a   Kruchten, Patricia ^b   Bey, Emmanuel ^b   Maier, Sebastian K G ^a   Fritzemeier, Karl Heinrich ^c   Prelle, Katja ^c   Hegele Hartung, Christa ^c   Hartmann, Rolf W ^b   Neyses, Ludwig ^d   Ertl, Georg ^a   Pelzer, Theo ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c BAYER PHARMA AG   (Germany)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Aging; Cardiac hypertrophy; Estrogen receptors; Hypertension

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; TESTOSTERONE 17BETA DEHYDROGENASE; TESTOSTERONE 17BETA DEHYDROGENASE 1; HYDROXYSTEROID DEHYDROGENASE; ISOENZYME; MUSCLE PROTEIN; MYOSIN HEAVY CHAIN; SEX HORMONE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENDOMETRIUM ATROPHY; ENZYME ACTIVITY; ESTRADIOL BLOOD LEVEL; ESTROGEN METABOLISM; ESTROGEN THERAPY; ESTRONE BLOOD LEVEL; FEMALE; GENE EXPRESSION; HEART VENTRICLE HYPERTROPHY; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SENESCENCE; SPONTANEOUSLY HYPERTENSIVE RAT; SUBSTITUTION THERAPY; ANIMAL; BLOOD; BLOOD PRESSURE; CARDIOMEGALY; DRUG EFFECT; HEART MUSCLE; HEMODYNAMICS; HYPERTENSION; METABOLISM; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; TELEMETRY;

17-HYDROXYSTEROID DEHYDROGENASES; AGING; ANIMALS; BLOOD PRESSURE; CARDIOMEGALY; ESTRADIOL; FEMALE; GONADAL STEROID HORMONES; HEMODYNAMIC PROCESSES; HYPERTENSION; ISOENZYMES; MUSCLE PROTEINS; MYOCARDIUM; MYOSIN HEAVY CHAINS; ORGAN SIZE; RATS; RATS, INBRED SHR; TELEMETRY;

EID: 33750593096     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000240053.48517.c7     Document Type: Article

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