Ageing-related cardiomyocyte functional decline is sex and angiotensin II dependent

Age

Volumn 36, Issue 3, 2014, Pages 1155-1167

  Mellor, Kimberley M ^a,d   Curl, Claire L ^a   Chandramouli, Chanchal ^a   Pedrazzini, Thierry ^b   Wendt, Igor R ^c   Delbridge, Lea M D ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Ageing; Angiotensin overexpression; Arrhythmogenesis; Calcium; Excitation contraction coupling; Failure; Hypertrophy

Indexed keywords

ANGIOTENSIN II; CALCIUM ION; RNA;

ADULT; AGE; AGED; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CYTOSOL; FEMALE; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; JUVENILE ANIMAL; MALE; MOUSE; MUSCLE TWITCH; MYOFILAMENT; NONHUMAN; SEX DIFFERENCE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

AGING; ANGIOTENSIN II; ANIMALS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RENIN-ANGIOTENSIN SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 84905368161     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-014-9630-7     Document Type: Article

References (50)

1. Ahmed A (2003) American College of Cardiology/American Heart Association Chronic Heart Failure Evaluation and Management guidelines: relevance to the geriatric practice. J Am Geriatr Soc 51:123-126
2. Asp ML, Martindale JJ, Heinis FI, Wang W, Metzger JM (2012) Calcium mishandling in diastolic dysfunction: mechanisms and potential therapies. Biochim Biophys Acta
3. Baker KM, Chernin MI, Schreiber T, Sanghi S, Haiderzaidi S, Booz GW, Dostal DE, Kumar R (2004) Evidence of a novel intracrine mechanism in angiotensin II-induced cardiac hypertrophy. Regul Pept 120:5-13 (Pubitemid 38726186)
4. Barsheshet A, Brenyo A, Goldenberg I, Moss AJ (2012) Sex-related differences in patients' responses to heart failure therapy. Nat Rev Cardiol 9:234-242
5. Bell JR, Bernasochi GB, Varma U, Raaijmakers AJ, Delbridge LM (2013) Sex and sex hormones in cardiac stress-mechanistic insights. J Steroid Biochem Mol Biol
6. Bers DM (2001) Excitation-contraction coupling and cardiac contractile force, 2nd edn. Kluwer Academic, Dordrecht
7. Bhatnagar GM, Walford GD, Beard ES, Humphreys S, Lakatta EG (1984) ATPase activity and force production in myofibrils and twitch characteristics in intact muscle from neonatal, adult, and senescent rat myocardium. J Mol Cell Cardiol 16:203-218 (Pubitemid 14168012)
8. Brown RD, Hilliard LM, Head GA, Jones ES, Widdop RE, Denton KM (2012) Sex differences in the pressor and tubuloglomerular feedback response to angiotensin II. Hypertension 59:129-135
9. Bupha-Intr T, Laosiripisan J, Wattanapermpool J (2009) Moderate intensity of regular exercise improves cardiac SR Ca2+ uptake activity in ovariectomized rats. J Appl Physiol 107:1105-1112
10. Bupha-Intr T, Wattanapermpool J (2006) Regulatory role of ovarian sex hormones in calcium uptake activity of cardiac sarcoplasmic reticulum. Am J Physiol Heart Circ Physiol 291:H1101-H1108 (Pubitemid 44343653)
11. Ceylan-Isik AF, Li Q, Ren J (2011) Insulin-like growth factor I (IGF-1) deficiency ameliorates sex difference in cardiac contractile function and intracellular Ca(2+) homeostasis. Toxicol Lett 206:130-138
12. de Giuli F, Khaw KT, Cowie MR, Sutton GC, Ferrari R, Poole-Wilson PA (2005) Incidence and outcome of persons with a clinical diagnosis of heart failure in a general practice population of 696,884 in the United Kingdom. Eur J Heart Fail 7:295-302 (Pubitemid 40249521)
13. Domenighetti AA, Boixel C, Cefai D, Abriel H, Pedrazzini T (2007) Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation. J Mol Cell Cardiol 42:63-70 (Pubitemid 44958628)
14. Domenighetti AA, Pedrazzini T, Delbridge LMD (2001) Abnormal contractile function in cardiomyocytes from transgenic mice overexpressing AngII in the heart. Proc. Renin Angiotensin-Aldosterone System Satellite of the XXXIV. Congress of the International Union of Physiological Science, Melbourne
15. Domenighetti AA, Wang Q, Egger M, Richards SM, Pedrazzini T, Delbridge LM (2005) Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure. Hypertension 46:426-432 (Pubitemid 41099180)
16. Dostal DE, Baker KM (1993) Evidence for a role of an intracardiac renin-angiotensin system in normal and failing hearts. Trends Cardiovasc Med 3:67-74 (Pubitemid 23131044)
17. Durand JB (2002) Current guidelines in heart failure management. Ethn Dis 12:S1-3-11
18. Feldmer M, Kaling M, Takahashi S, Mullins JJ, Ganten D (1991) Glucocorticoid- and estrogen-responsive elements in the 5′-flanking region of the rat angiotensinogen gene. J Hypertens 9:1005-1012
19. Gomez AM, Richard S (2004) Mutant cardiac ryanodine receptors and ventricular arrhythmias: is 'gain-of-function' obligatory? Cardiovasc Res 64:3-5 (Pubitemid 39208916)
20. Gusev K, Domenighetti AA, Delbridge LM, Pedrazzini T, Niggli E, Egger M (2009) Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling. Circ Res 105:42-50
21. Heymes C, Silvestre JS, Llorens-Cortes C, Chevalier B, Marotte F, Levy BI, Swynghedauw B, Samuel JL (1998) Cardiac senescence is associated with enhanced expression of angiotensin II receptor subtypes. Endocrinology 139:2579-2587 (Pubitemid 28513788)
22. Heymes C, Swynghedauw B, Chevalier B (1994) Activation of angiotensinogen and angiotensin-converting enzyme gene expression in the left ventricle of senescent rats. Circulation 90:1328-1333 (Pubitemid 24284454)
23. Howlett SE (2010) Age-associated changes in excitation-contraction coupling are more prominent in ventricular myocytes from male rats than in myocytes from female rats. Am J Physiol Heart Circ Physiol 298:H659-H670
24. Huggins CE, Curl CL, Patel R, McLennan PL, Theiss ML, Pedrazzini T, Pepe S, Delbridge LM (2009) Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice. Am J Physiol Heart Circ Physiol 296:H957-H966
25. Huggins CE, Domenighetti AA, Pedrazzini T, Pepe S, Delbridge LM (2003) Elevated intracardiac angiotensin II leads to cardiac hypertrophy and mechanical dysfunction in normotensive mice. J Renin Angiotensin Aldosterone Syst 4:186-190 (Pubitemid 37407167)
26. Ikenouchi H, Barry WH, Bridge JH, Weinberg EO, Apstein CS, Lorell BH (1994) Effects of angiotensin II on intracellular Ca2+ and pH in isolated beating rabbit hearts and myocytes loaded with the indicator indo-1. J Physiol 480(Pt 2):203-215 (Pubitemid 24340927)
27. Kannel WB, Wilson PW, D'Agostino RB, Cobb J (1998) Sudden coronary death in women. Am Heart J 136:205-212 (Pubitemid 28368840)
28. Kockskamper J, Zima AV, Blatter LA (2005) Modulation of sarcoplasmic reticulum Ca2+ release by glycolysis in cat atrial myocytes. J Physiol 564:697-714 (Pubitemid 40704138)
29. Kunstyr I, Leuenberger HG (1975) Gerontological data of C57BL/6 J mice. I. Sex differences in survival curves. J Gerontol 30:157-162
30. Larson MG (1995) Assessment of cardiovascular risk factors in the elderly: the Framingham Heart Study. Stat Med 14:1745-1756
31. Lindpaintner K, Ganten D (1991) The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence. Circ Res 68:905-921
32. Liu CG, Xu KQ, Xu X, Huang JJ, Xiao JC, Zhang JP, Song HP (2007) 17Beta-oestradiol regulates the expression of Na+/K+-ATPase beta1-subunit, sarcoplasmic reticulum Ca2+-ATPase and carbonic anhydrase iv in H9C2 cells. Clin Exp Pharmacol Physiol 34:998-1004 (Pubitemid 47274551)
33. Malhotra A, Kang BP, Cheung S, Opawumi D, Meggs LG (2001) Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I. Diabetes 50:1918-1926 (Pubitemid 33641614)
34. Maric C (2005) Sex differences in cardiovascular disease and hypertension: involvement of the renin-angiotensin system. Hypertension 46:475-476
35. Mattiazzi A (1997) Positive inotropic effect of angiotensin II. Increases in intracellular Ca2+ or changes in myofilament Ca2+ responsiveness? J Pharmacol Toxicol Methods 37:205-214
36. Mazzolai L, Nussberger J, Aubert JF, Brunner DB, Gabbiani G, Brunner HR, Pedrazzini T (1998) Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension 31:1324-1330 (Pubitemid 28248835)
37. Mazzolai L, Pedrazzini T, Nicoud F, Gabbiani G, Brunner HR, Nussberger J (2000) Increased cardiac angiotensin II levels induce right and left ventricular hypertrophy in normotensive mice. Hypertension 35:985-991 (Pubitemid 30303962)
38. Mellor KM, Wendt IR, Ritchie RH, Delbridge LM (2012) Fructose diet treatment in mice induces fundamental disturbance of cardiomyocyte Ca2+ handling and myofilament responsiveness. Am J Physiol Heart Circ Physiol 302:H964-H972
39. Parks RJ, Howlett SE (2013) Sex differences in mechanisms of cardiac excitation-contraction coupling. Pflugers Arch 465:747-763
40. Pellieux C, Aasum E, Larsen TS, Montessuit C, Papageorgiou I, Pedrazzini T, Lerch R (2006) Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway. JMol Cell Cardiol 41:459-466 (Pubitemid 44344282)
41. Pellieux C, Sauthier T, Aubert JF, Brunner HR, Pedrazzini T (2000) Angiotensin II-induced cardiac hypertrophy is associated with different mitogen-activated protein kinase activation in normotensive and hypertensive mice. J Hypertens 18:1307-1317
42. Rabi DM, Khan N, Vallee M, Hladunewich MA, Tobe SW, Pilote L (2008) Reporting on sex-based analysis in clinical trials of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker efficacy. Can J Cardiol 24:491-496
43. Regitz-Zagrosek V, Lehmkuhl E (2005) Heart failure and its treatment in women. Role of hypertension, diabetes, and estrogen. Herz 30:356-367 (Pubitemid 41238953)
44. Rivard K, Grandy SA, Douillette A, Paradis P, Nemer M, Allen BG, Fiset C (2011) Overexpression of type 1 angiotensin II receptors impairs excitation-contraction coupling in the mouse heart. Am J Physiol Heart Circ Physiol 301:H2018-H2027
45. Roger VL, Weston SA, Redfield MM, Hellermann-Homan JP, Killian J, Yawn BP, Jacobsen SJ (2004) Trends in heart failure incidence and survival in a community-based population. Jama 292:344-350 (Pubitemid 38944258)
46. Seeland U and Regitz-Zagrosek V (2012) Sex and gender differences in cardiovascular drug therapy. Handb Exp Pharmacol 211-236
47. Shekelle PG, Rich MW, Morton SC, Atkinson CS, Tu W, Maglione M, Rhodes S, Barrett M, Fonarow GC, Greenberg B, Heidenreich PA, Knabel T, Konstam MA, Steimle A, Warner Stevenson L (2003) Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status: a meta-analysis of major clinical trials. J Am Coll Cardiol 41:1529-1538 (Pubitemid 36543372)
48. Spurgeon HA, duBell WH, Stern MD, Sollott SJ, Ziman BD, Silverman HS, Capogrossi MC, Talo A, Lakatta EG (1992) Cytosolic calcium and myofilaments in single rat cardiac myocytes achieve a dynamic equilibrium during twitch relaxation. J Physiol 447:83-102
49. Sullivan JC (2008) Sex and the renin-angiotensin system: inequality between the sexes in response to RAS stimulation and inhibition. Am J Physiol Regul Integr Comp Physiol 294:R1220-R1226
50. Unger T, Li J (2004) The role of the renin-angiotensin-aldosterone systemin heart failure. J Renin Angiotensin Aldosterone Syst 5(Suppl 1):S7-S10 (Pubitemid 39406441)