Revealing G-protein-coupled receptor oligomerization at the single-molecule level through a nanoscopic lens: Methods, dynamics and biological function

FEBS Journal

Volumn 283, Issue 7, 2016, Pages 1197-1217

  Scarselli, Marco ^a   Annibale, Paolo ^b   McCormick, Peter J ^c   Kolachalam, Shivakumar ^a   Aringhieri, Stefano ^a   Radenovic, Aleksandra ^b   Corsini, Giovanni U ^a   Maggio, Roberto ^d  

^a UNIVERSITY OF PISA   (Italy)

^b EPFL   (Switzerland)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

actin cytoskeleton; G protein coupled receptor; oligomerization; photoactivated localization microscopy; single molecule microscopy; 2 adrenergic receptor

Indexed keywords

DIMER; G PROTEIN COUPLED RECEPTOR; OLIGOMER; PROTEIN BINDING;

ACTIN FILAMENT; ANALYTIC METHOD; BIOLOGICAL ACTIVITY; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; DIMERIZATION; DISSOCIATION; FLUORESCENCE CORRELATION SPECTROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTERMETHOD COMPARISON; MICROSCOPY; MOLECULAR DYNAMICS; NONHUMAN; OLIGOMERIZATION; PHOTOACTIVATED LOCALIZATION MICROSCOPY; PRIORITY JOURNAL; REVIEW; SINGLE MOLECULE TRACKING; STEADY STATE; ANIMAL; CHEMISTRY; DEVICES; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; NANOTECHNOLOGY; PROCEDURES; PROTEIN MULTIMERIZATION; REPRODUCIBILITY;

ACTIN CYTOSKELETON; ANIMALS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR DYNAMICS SIMULATION; NANOTECHNOLOGY; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECEPTORS, G-PROTEIN-COUPLED; REPRODUCIBILITY OF RESULTS;

EID: 84962960723     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13577     Document Type: Review

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