Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells

FASEB Journal

Volumn 22, Issue 3, 2008, Pages 850-860

  Cordeaux, Y ^a,b   Briddon, S J ^a   Alexander, S P H ^a   Kellam, B ^a   Hill, S J ^a,c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

Confocal imaging; Fluorescence correlation spectroscopy; GPCRs

Indexed keywords

9 CHLORO 2 (2 FURYL) 5 PHENYLACETYLAMINO 1,2,4 TRIAZOLO[1,5 C]QUINAZOLINE; ADENOSINE A3 RECEPTOR AGONIST; CYCLIC AMP; FORSKOLIN; N ETHYL 3,4 DIHYDROXY 5 [6 [4 [6 [2 [4 [2 [4,4 DIFLUORO 4,4A DIHYDRO 5 (THIOPHEN 2 YL) 4 BORA 3A,4A DIAZA S INDACENE 3 YL]VINYL]PHENOXY]ACETAMIDO]HEXAN AMIDO]BUTYLAMINO] 9H PURIN 9 YL]TETRAHYDROFURAN 2 CARBOXAMIDE; PHOSPHATIDYLINOSITIDE; UNCLASSIFIED DRUG; ABEA X BY630; ABEA-X-BY630; ADENOSINE; ADENOSINE A3 RECEPTOR; BORON DERIVATIVE; DRUG DERIVATIVE; FLUORESCENT DYE; LIGAND;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHO CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIFFUSION COEFFICIENT; FLUORESCENCE CORRELATION SPECTROSCOPY; HUMAN; HUMAN CELL; HYDROLYSIS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; ANIMAL; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; CRICETULUS; DRUG POTENTIATION; FLUORESCENCE MICROSCOPY; HAMSTER; MACROMOLECULE; METABOLISM; METHODOLOGY;

CRICETULUS GRISEUS;

ADENOSINE; ANIMALS; BINDING, COMPETITIVE; BORON COMPOUNDS; CHO CELLS; CRICETINAE; CRICETULUS; FLUORESCENT DYES; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MEMBRANE MICRODOMAINS; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; RECEPTOR, ADENOSINE A3;

EID: 40449125151     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8180com     Document Type: Article

References (48)